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BIO 3N: Views of a Changing Sea: Literature & Science

The state of a changing world ocean, particularly in the eastern Pacific, will be examined through historical and contemporary fiction, non-fiction and scientific publications. Issues will include harvest and mariculture fisheries, land-sea interactions and oceanic climate change in both surface and deep waters.
Terms: Spr | Units: 3 | UG Reqs: GER: DB-NatSci
Instructors: ; Gilly, W. (PI)

BIO 30: Ecology for Everyone (EARTHSYS 30)

Everything is connected, but how? Ecology is the science of interactions and the changes they generate. This project-based course links individual behavior, population growth, species interactions, and ecosystem function. Introduction to measurement, observation, experimental design and hypothesis testing in field projects, mostly done in groups. The goal is to learn to think analytically about everyday ecological processes involving bacteria, fungi, plants, animals and humans. The course uses basic statistics to analyze data; there are no math prerequisites except arithmetic. Open to everyone, including those who may be headed for more advanced courses in ecology and environmental science.
Terms: Spr | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Gordon, D. (PI)

BIO 43: Plant Biology, Evolution, and Ecology

Principles of evolution: macro- and microevolution and population genetics. Ecology: the principles underlying the exchanges of mass and energy between organisms and their environments; population, community, and ecosystem ecology; populations, evolution, and global change. Equivalent to BIOHOPK 43. Prerequisites: CHEM 31X (or 31A,B), 33. Recommended: BIO 41, 42; CHEM 35; MATH 19, 20, 21 or 41, 42.
Terms: Spr | Units: 5 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIO 43A: Bio Solve-It

Students enrolled in Bio43 lecture and regular discussion sections attend an additional 75 min section. The objective of the course is to help students to solidify basic concepts, identify areas to work on, and apply core concepts learned that week in Bio43 lecture and section. Space is limited, by application only. Click to apply. Application deadline = March 20, 2015. Co-Requisite: Bio 43
Terms: Spr | Units: 1

BIO 44Y: Core Plant Biology & Eco Evo Laboratory

The goal of this course is to develop an understanding of how to conduct biological research, using a topic in Ecology, Evolutionary Biology, and Plant Biology as a practical example. This includes the complete scientific process: assessing background literature, generating testable hypotheses, learning techniques for field- and lab-based data collection, analyzing data using appropriate statistical methods, and finally writing and sharing results. To build these skills, this course will focus on communities of microorganisms living in floral nectar at Stanford's nearby Jasper Ridge Biological Preserve. Students, working in teams, will develop novel research hypotheses and execute the necessary experiments and measurements to test these hypotheses. The capstone of the course will be an oral defense of students' findings, as well as a research paper in the style of a peer-reviewed journal article. Labs will be completed both on campus and at Jasper Ridge. Lab fee. Information about this class is available at http://bio44.stanford.edu. Satisfies WIM in Biology.
Terms: Spr | Units: 5 | UG Reqs: WAY-SMA

BIO 105B: Ecology and Natural History of Jasper Ridge Biological Preserve (EARTHSYS 105B)

Formerly 96B - Jasper Ridge Docent Training. First of two-quarter sequence training program to join the Jasper Ridge education/docent program. The scientific basis of ecological research in the context of a field station, hands-on field research, field ecology and the natural history of plants and animals, species interactions, archaeology, geology, hydrology, land management, multidisciplinary environmental education; and research projects, as well as management challenges of the preserve presented by faculty, local experts, and staff. Participants lead research-focused educational tours, assist with classes and research, and attend continuing education classes available to members of the JRBP community after the course.
Terms: Spr | Units: 4

BIO 107: Human Physiology Laboratory (HUMBIO 136)

This laboratory course is inquiry based, so the subject matter of the course will change in successive years. In 2015, the two questions to be researched concurrently in Spring will be (1) Can heat-related performance decrements incurred by individuals clad in impermeable attire (e.g., biohazard personal protective suits) be mitigated?¿ and (2) Can the sensation of thermal comfort be affected by regional skin temperature manipulations.nStudents will participate both as experimenters and as subjects. The laboratory work will focus on exercise and temperature. Thus, participants must be in good physical condition and be willing to participate in strenuous exercise routines under adverse environmental conditions. Varsity athletes currently participating in a spring sport should first talk with Prof. Heller before applying.nCombined Lab/Discussion sessions will be Tue and Thurs 1:15 - 5:05. You must attend both days each week, with no conflicts with other courses.nPrerequisite is Bio 42 or HumBio 4A. Satisfies WIM for majors in biology. nEnrollment for Spring 2015 course is limited to 16 students by permission.nSee: sites.stanford.edu/bio107 for the link to online application form.
Terms: Spr | Units: 4

BIO 109B: The Human Genome and Disease: Genetic Diversity and Personalized Medicine (BIOC 109B, BIOC 209B)

Continuation of 109A/209A. Genetic drift: the path of human predecessors out of Africa to Europe and then either through Asia to Australia or through northern Russia to Alaska down to the W. Coast of the Americas. Support for this idea through the histocompatibility genes and genetic sequences that predispose people to diseases. Guest lectures from academia and pharmaceutical companies. Prerequisite: Biology or Human Biology core. Students with a major, minor or coterm in Biology: 109A/209A or 109B/209B may count toward degree program but not both.
Terms: Spr | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIO 128: Geographic Impacts of Global Change: Mapping the Stories (EARTHSYS 129)

Forces of global change (eg., climate disruption, biodiversity loss, disease) impart wide-ranging political, socioeconomic, and ecological impacts, creating an urgent need for science communication. Students will collect data for a region of the US using sources ranging from academic journals to popular media and create an interactive Story Map (http://stanford.maps.arcgis.com/apps/StorytellingTextLegend/index.html?appid=dafe2393fd2e4acc8b0a4e6e71d0b6d5) that merges the scientific and human dimensions of global change. Students will interview stakeholders as part of a community-engaged learning experience and present the Map to national policy-makers. Our 2014 Map is being used by the CA Office of Planning & Research.
Terms: Aut, Spr | Units: 4

BIO 129B: Cellular Dynamics II: Building a Cell

Principles of cell organization; how common biochemical pathways are modified to generate diversity in cell structure and function. Roles of actin and microtubule cytoskeletons in cellular architecture. Mechanisms of protein sorting and trafficking, and protein modules and switches in regulating cell polarity. Yeast to polarized epithelial cells and neurons. Emphasis is on experimental logic, methods, problem solving, and interpretation of results. Students present research papers. Satisfies Central Menu Area 2. Prerequisite: Biology core. Recommended: 129A.
Terms: Spr | Units: 4 | UG Reqs: GER: DB-NatSci

BIO 132: Advanced Imaging Lab in Biophysics (APPPHYS 232, BIO 232, BIOPHYS 232, GENE 232)

Laboratory and lectures. Advanced microscopy and imaging, emphasizing hands-on experience with state-of-the-art techniques. Students construct and operate working apparatus. Topics include microscope optics, Koehler illumination, contrast-generating mechanisms (bright/dark field, fluorescence, phase contrast, differential interference contrast), and resolution limits. Laboratory topics vary by year, but include single-molecule fluorescence, fluorescence resonance energy transfer, confocal microscopy, two-photon microscopy, microendoscopy, and optical trapping. Limited enrollment. Recommended: basic physics, Biology core or equivalent, and consent of instructor.
Terms: Spr | Units: 4 | UG Reqs: GER: DB-NatSci

BIO 143: Evolution

Principles of evolution. Adaptation and natural selection. Darwin and the history of evolutionary thought. Population genetics, including genetic variation and mutation, and effects of migration, drift, linkage, and recombination. Evolutionary phenomena: developmental evolution, life history evolution, molecular evolution, sexual selection, social evolution, and speciation. Pattern and process in biological diversity. Case studies, including human evolution. Satisfies central menu area 4, ecology & evolution.
Terms: Spr | Units: 3 | UG Reqs: GER: DB-NatSci

BIO 144: Conservation Biology: A Latin American Perspective (BIO 234, HUMBIO 112)

Principles and application of the science of preserving biological diversity. Conceptually, this course is designed to explore 4 major components relevant to the conservation of biodiversity, as exemplified by the Latin American region. The conceptual frameworks and principles, however, should be generally applicable, and provide insights for all regions of the world, including those of lesser biodiversity. Satisfies Central Menu Area 4 for Bio majors. Prerequisite: BIO 101, or BIO 43 or HUMBIO 2A with consent of instructor. Graduate level students will be expected to conduct a literature research exercise leading to a written paper, addressing a topic of their choosing, derived from any of the themes discussed in class.
Terms: Spr | Units: 3 | UG Reqs: GER: DB-NatSci

BIO 145: Ecology and evolution of animal behavior (BIO 245)

Ecological and evolutionary perspectives on animal behavior, with an emphasis on social and collective behavior. This is a project-based course in a lecture/seminar format. Seminars will be based on discussion of journal articles. Independent research projects on the behavior of animals on campus. Prerequisites: Biology or Human Biology core, Biology/ES 30. Recommended: statistics.
Terms: Spr | Units: 3 | UG Reqs: GER: DB-NatSci
Instructors: ; Gordon, D. (PI)

BIO 154: Molecular and Cellular Neurobiology

For advanced undergraduate students. Cellular and molecular mechanisms in the organization and functions of the nervous system. Topics: wiring of the neuronal circuit, synapse structure and synaptic transmission, signal transduction in the nervous system, sensory systems, molecular basis of behavior including learning and memory, molecular pathogenesis of neurological diseases. Satisfies Central Menu Areas 2 or 3 for Bio majors. Prerequisite for undergraduates: Biology core or equivalent, or consent of instructors.
Terms: Spr | Units: 4 | UG Reqs: GER: DB-NatSci

BIO 156: Epigenetics (BIO 256)

Epigenetics is the process by which phenotypes not determined by the DNA sequence are stably inherited in successive cell divisions. Course will cover the molecular mechanisms governing epigenetics, ranging from the discovery of epigenetic phenomena to present-day studies on the role of chromatin, DNA methylation, and RNA in regulating epigenetics processes. Topics include: position effect gene expression, genome regulation, gene silencing & heterochromatin, histone code, DNA methylation & imprinting, epigenetics & disease, and epigenetic-based therapeutics. Prerequisite: BIO41 and BIO42 or consent of instructor, advanced biology course such as Bio104
Terms: Spr | Units: 2
Instructors: ; Gozani, O. (PI); Lee, L. (TA)

BIO 196C: Biology Senior Reflection

Capstone course series for seniors. Creative, self-reflective and scientifically relevant projects conceived, produced and exhibited over the course of three quarters. Explore scientific content of personal interest through creative forms including but not limited to writing, music, fine arts, performing arts, photography, film or new media. A written essay on the creative process and scientific significance of the selected topic will accompany the creative work. Completed projects may be included in a creative portfolio. Required enrollment in 196A,B,C.
Terms: Spr | Units: 3 | UG Reqs: WAY-CE

BIO 197WA: Senior Writing Project: The Personal Essay in Biology

Seminar focused on writing. Compose, workshop and revise scientifically relevant and personal essays in biology directed at a mainstream audience, interweaving research, interview, memoir, and other elements of nonfiction craft. Satisfies WIM in Biology.
Terms: Spr | Units: 3
Instructors: ; Todhunter, A. (PI)

BIO 198X: Out-of-Department Directed Reading

Individually arranged under the supervision of members of the faculty. Credit for work arranged with out-of-department faculty is restricted to Biology majors and requires department approval. See http://biohonors.stanford.edu for information and petitions. May be repeated for credit.
Terms: Aut, Win, Spr, Sum | Units: 1-15 | Repeatable 10 times (up to 60 units total)
Instructors: ; Bergmann, D. (PI); Block, B. (PI); Block, S. (PI); Boggs, C. (PI); Chan, P. (PI); Cimprich, K. (PI); Clandinin, T. (PI); Contag, C. (PI); Cooke, J. (PI); Crowder, L. (PI); Cyert, M. (PI); Daily, G. (PI); Darian-Smith, C. (PI); Denny, M. (PI); Dirzo, R. (PI); Ehrlich, P. (PI); Feldman, M. (PI); Fernald, R. (PI); Field, C. (PI); Fraser, H. (PI); Frommer, W. (PI); Frydman, J. (PI); Fukami, T. (PI); Gardner, C. (PI); Gilly, W. (PI); Gold, G. (PI); Goodman, M. (PI); Goodman, S. (PI); Gordon, D. (PI); Gozani, O. (PI); Graves, E. (PI); Hadly, E. (PI); Hallmayer, J. (PI); Hanawalt, P. (PI); Heilshorn, S. (PI); Heller, H. (PI); Herzenberg, L. (PI); Hestrin, S. (PI); Hsu, S. (PI); Jones, P. (PI); Khalfan, W. (PI); Khavari, P. (PI); Klein, R. (PI); Kobilka, B. (PI); Koong, A. (PI); Kopito, R. (PI); Krams, S. (PI); Kuo, C. (PI); Levy, R. (PI); Lipsick, J. (PI); Long, S. (PI); Lowe, C. (PI); Luo, L. (PI); Lyons, D. (PI); Maduke, M. (PI); Manber, R. (PI); McConnell, S. (PI); Micheli, F. (PI); Michie, S. (PI); Mooney, H. (PI); Morrison, A. (PI); Mudgett, M. (PI); Nelson, W. (PI); O'hara, R. (PI); Ormond, K. (PI); Palumbi, S. (PI); Peehl, D. (PI); Petrov, D. (PI); Plant, G. (PI); Pritchard, J. (PI); Raymond, J. (PI); Red-Horse, K. (PI); Root, T. (PI); Rosenberg, N. (PI); Sapolsky, R. (PI); Sarnow, P. (PI); Schnitzer, M. (PI); Shatz, C. (PI); Shen, K. (PI); Simon, M. (PI); Simoni, R. (PI); Skotheim, J. (PI); Somero, G. (PI); Spormann, A. (PI); Stearns, T. (PI); Steinberg, G. (PI); Thompson, S. (PI); Tuljapurkar, S. (PI); Vitousek, P. (PI); Walbot, V. (PI); Watt, W. (PI); Weissman, I. (PI); Wine, J. (PI); Yang, Y. (PI); Collins, J. (GP)

BIO 199: Advanced Research Laboratory in Experimental Biology

Individual research taken by arrangement with in-department instructors. See http://biohonors.stanford.edu for information on research sponsors, units, and credit for summer research. May be repeated for credit.
Terms: Aut, Win, Spr, Sum | Units: 1-15 | Repeatable 15 times (up to 60 units total)

BIO 199X: Out-of-Department Advanced Research Laboratory in Experimental Biology

Individual research by arrangement with out-of-department instructors. Credit for 199X is restricted to declared Biology majors and requires department approval. See http://biohonors.stanford.edu for information on research sponsors, units, petitions, deadlines, credit for summer research, and out-of-Stanford research. May be repeated for credit.
Terms: Aut, Win, Spr, Sum | Units: 1-15 | Repeatable 15 times (up to 60 units total)
Instructors: ; Agras, W. (PI); Altman, R. (PI); Andriacchi, T. (PI); Arrigo, K. (PI); Artandi, S. (PI); Arvin, A. (PI); Attardi, L. (PI); Axelrod, J. (PI); Baker, J. (PI); Barr, D. (PI); Barres, B. (PI); Barsh, G. (PI); Batzoglou, S. (PI); Beachy, P. (PI); Bergmann, D. (PI); Bernstein, D. (PI); Bhalla, V. (PI); Bhutani, N. (PI); Blaschke, T. (PI); Blau, H. (PI); Block, B. (PI); Block, S. (PI); Boehm, A. (PI); Boggs, C. (PI); Bogyo, M. (PI); Boothroyd, J. (PI); Boxer, L. (PI); Boxer, S. (PI); Brown, J. (PI); Brown, P. (PI); Brundage, S. (PI); Brunet, A. (PI); Brunger, A. (PI); Brutlag, D. (PI); Buckmaster, P. (PI); Butcher, E. (PI); Butte, M. (PI); Calos, M. (PI); Cartwright, C. (PI); Chan, P. (PI); Chang, H. (PI); Chang, S. (PI); Chase, R. (PI); Chawla, A. (PI); Chen, J. (PI); Chen, L. (PI); Cheng, A. (PI); Chien, Y. (PI); Chu, G. (PI); Cimprich, K. (PI); Clandinin, T. (PI); Clarke, M. (PI); Cleary, M. (PI); Cochran, J. (PI); Cohen, H. (PI); Cohen, S. (PI); Collman, J. (PI); Conley, F. (PI); Contag, C. (PI); Cooke, J. (PI); Cooper, A. (PI); Crabtree, G. (PI); Criddle, C. (PI); Crowder, L. (PI); Cyert, M. (PI); Daily, G. (PI); Darian-Smith, C. (PI); Das, R. (PI); Davis, M. (PI); Davis, R. (PI); Deisseroth, K. (PI); Dement, W. (PI); Denny, M. (PI); Dhabhar, F. (PI); Dirzo, R. (PI); Dolmetsch, R. (PI); Doniach, S. (PI); Dorfman, L. (PI); Ehrhardt, D. (PI); Ehrlich, P. (PI); Einav, S. (PI); Engleman, E. (PI); Epel, D. (PI); Falcon, W. (PI); Falkow, S. (PI); Fathman, C. (PI); Feldman, B. (PI); Feldman, D. (PI); Feldman, M. (PI); Felsher, D. (PI); Fernald, R. (PI); Ferrell, J. (PI); Field, C. (PI); Fire, A. (PI); Ford, J. (PI); Fortmann, S. (PI); Foung, S. (PI); Francke, U. (PI); Fraser, H. (PI); Frydman, J. (PI); Fuller, M. (PI); Galli, S. (PI); Gambhir, S. (PI); Gardner, P. (PI); Garner, C. (PI); Garner, J. (PI); Gesundheit, N. (PI); Giaccia, A. (PI); Gilly, W. (PI); Glenn, J. (PI); Gold, G. (PI); Goodman, M. (PI); Goodman, S. (PI); Gordon, D. (PI); Gozani, O. (PI); Gray, G. (PI); Greenberg, H. (PI); Greicius, M. (PI); Gross, E. (PI); Guilleminault, C. (PI); Guzman, R. (PI); Hadly, E. (PI); Hallmayer, J. (PI); Hanawalt, P. (PI); Haskell, W. (PI); Heilshorn, S. (PI); Heller, H. (PI); Helms, J. (PI); Herschlag, D. (PI); Herzenberg, L. (PI); Hestrin, S. (PI); Hodgson, K. (PI); Hoffman, A. (PI); Hoffman, B. (PI); Hogness, D. (PI); Hsu, S. (PI); Hsueh, A. (PI); Huestis, W. (PI); Huguenard, J. (PI); Jackson, P. (PI); Jardetzky, O. (PI); Jones, P. (PI); Kahn, D. (PI); Kaiser, A. (PI); Kao, P. (PI); Karasek, M. (PI); Katzenstein, D. (PI); Kay, M. (PI); Kendig, J. (PI); Khavari, P. (PI); Kim, S. (PI); King, A. (PI); Kingsley, D. (PI); Knope, M. (PI); Knox, S. (PI); Knudsen, E. (PI); Knutson, B. (PI); Kobilka, B. (PI); Koong, A. (PI); Kopito, R. (PI); Kornberg, A. (PI); Kornberg, R. (PI); Koseff, J. (PI); Kraemer, F. (PI); Krams, S. (PI); Krasnow, M. (PI); Krensky, A. (PI); Kuo, C. (PI); Lee, P. (PI); Lehman, I. (PI); Leung, L. (PI); Levenston, M. (PI); Levitt, M. (PI); Levy, R. (PI); Levy, S. (PI); Lewis, D. (PI); Lewis, R. (PI); Li, G. (PI); Lipsick, J. (PI); Litt, I. (PI); Long, S. (PI); Longaker, M. (PI); Lorenz, H. (PI); Lowe, A. (PI); Lowe, C. (PI); Lu, B. (PI); Luo, L. (PI); Lyons, D. (PI); MacIver, M. (PI); Mackey, S. (PI); Madison, D. (PI); Maduke, M. (PI); Majeti, R. (PI); Maldonado, Y. (PI); Malenka, R. (PI); Marcus, R. (PI); Marinkovich, M. (PI); Marmor, M. (PI); Martinez, O. (PI); Matheson, G. (PI); Matin, A. (PI); McConnell, H. (PI); McConnell, S. (PI); McDevitt, H. (PI); McKay, D. (PI); McMahan, U. (PI); Mellins, E. (PI); Menon, V. (PI); Merigan, T. (PI); Micheli, F. (PI); Michie, S. (PI); Mignot, E. (PI); Miklos, D. (PI); Miller, D. (PI); Mobley, W. (PI); Mocarski, E. (PI); Mochly-Rosen, D. (PI); Monack, D. (PI); Monje-Deisseroth, M. (PI); Mooney, H. (PI); Morris, R. (PI); Morrison, A. (PI); Morton, J. (PI); Mudgett, M. (PI); Murphy, G. (PI); Myers, B. (PI); Myers, R. (PI); Nadeau, K. (PI); Negrin, R. (PI); Nelson, W. (PI); Newsome, W. (PI); Nicolls, M. (PI); Nishino, S. (PI); Nolan, G. (PI); Nusse, R. (PI); O'hara, R. (PI); Oro, A. (PI); Palmer, T. (PI); Palumbi, S. (PI); Pande, V. (PI); Parham, P. (PI); Parker, K. (PI); Parnes, J. (PI); Parsonnet, J. (PI); Patterson, D. (PI); Pearl, R. (PI); Pecora, R. (PI); Peebles, R. (PI); Peehl, D. (PI); Petrov, D. (PI); Pfeffer, S. (PI); Plant, G. (PI); Pollack, J. (PI); Porteus, M. (PI); Porzig, E. (PI); Prince, D. (PI); Pringle, J. (PI); Puglisi, J. (PI); Quertermous, T. (PI); Rabinovitch, M. (PI); Raffin, T. (PI); Rando, T. (PI); Rasgon, N. (PI); Raymond, J. (PI); Reaven, G. (PI); Red-Horse, K. (PI); Reimer, R. (PI); Reiss, A. (PI); Relman, D. (PI); Riedel-Kruse, I. (PI); Robbins, R. (PI); Robertson, C. (PI); Robinson, B. (PI); Robinson, T. (PI); Rockson, S. (PI); Rohatgi, R. (PI); Rosen, G. (PI); Rosenberg, N. (PI); Roth, R. (PI); Rothschild, L. (PI); Roughgarden, J. (PI); Ruiz-Lozano, P. (PI); Sage, J. (PI); Sakamoto, K. (PI); Sapolsky, R. (PI); Sarnow, P. (PI); Schatzberg, A. (PI); Schneider, D. (PI); Schnitzer, M. (PI); Schoolnik, G. (PI); Schrier, S. (PI); Schwarz, T. (PI); Scott, M. (PI); Shamloo, M. (PI); Shapiro, L. (PI); Shatz, C. (PI); Shen, K. (PI); Shochat, S. (PI); Shooter, E. (PI); Sibley, E. (PI); Sikic, B. (PI); Silverberg, G. (PI); Simon, M. (PI); Simoni, R. (PI); Singh, U. (PI); Skirboll, S. (PI); Skotheim, J. (PI); Smith, M. (PI); Smith, R. (PI); Smith, S. (PI); Smolke, C. (PI); Snyder, M. (PI); Somero, G. (PI); Spiegel, D. (PI); Spormann, A. (PI); Spudich, J. (PI); Stamey, T. (PI); Stearns, T. (PI); Steele, C. (PI); Steinberg, G. (PI); Steinman, L. (PI); Stevens, D. (PI); Stevenson, D. (PI); Stockdale, F. (PI); Straight, A. (PI); Strober, S. (PI); Stryer, L. (PI); Sudhof, T. (PI); Sullivan, E. (PI); Sun, Z. (PI); Sweet-Cordero (PI); Ta, C. (PI); Talbot, W. (PI); Tan, M. (PI); Taylor, C. (PI); Teng, N. (PI); Theriot, J. (PI); Thompson, S. (PI); Triadafilopoulos, G. (PI); Tsao, P. (PI); Tse, V. (PI); Tsien, R. (PI); Tuljapurkar, S. (PI); Utz, P. (PI); Vemuri, M. (PI); Villeneuve, A. (PI); Vitousek, P. (PI); Vollrath, D. (PI); Walbot, V. (PI); Wandless, T. (PI); Wang, K. (PI); Wang, T. (PI); Watt, W. (PI); Waymouth, R. (PI); Weinberg, K. (PI); Weis, W. (PI); Weissman, I. (PI); Wernig, M. (PI); Whitlock, J. (PI); Wine, J. (PI); Winograd, C. (PI); Wong, A. (PI); Wong, D. (PI); Wu, J. (PI); Wu, S. (PI); Wyss-Coray, T. (PI); Yang, Y. (PI); Yao, M. (PI); Zajac, F. (PI); Zare, R. (PI); Zarins, C. (PI); Zehnder, J. (PI); Zeitzer, J. (PI); Zhao, H. (PI); de Lecea, L. (PI); Cisneros, S. (GP); Frank, D. (GP); Habebo, T. (GP); Jones, D. (GP); Mesa, J. (GP); Thompson, J. (GP)

BIO 204: Neuroplasticity: From Synapses to Behavior

This course will focus on neuroplasticity from a broad perspective, from molecular cellular mechanism to its involvement in behavior and diseases. Emphasis will be on: a) molecular and cellular mechanisms underlying various forms of neuroplasticity; b) the neuroplasticity during brain development; c) the neuroplasticity in adult brain with respect to learning and memory; and d) maladaptive neuroplasticity in neurodegenerative disease and drug addiction. This course is designed for Ph.D. students from both the Biology and Neuroscience programs. Open to advanced undergraduates by consent of instructor.
Terms: Spr | Units: 3
Instructors: ; Chen, X. (PI); Ding, J. (PI)

BIO 208: Spanish in Science/Science in Spanish (EARTHSYS 207, LATINAM 207)

For graduate and undergraduate students interested in the natural sciences and the Spanish language. Students will acquire the ability to communicate in Spanish using scientific language and will enhance their ability to read scientific literature written in Spanish. Emphasis on the development of science in Spanish-speaking countries or regions. Course is conducted in Spanish and intended for students pursuing degrees in the sciences, particularly disciplines such as ecology, environmental science, sustainability, resource management, anthropology, and archeology.
Terms: Spr | Units: 2
Instructors: ; Dirzo, R. (PI)

BIO 232: Advanced Imaging Lab in Biophysics (APPPHYS 232, BIO 132, BIOPHYS 232, GENE 232)

Laboratory and lectures. Advanced microscopy and imaging, emphasizing hands-on experience with state-of-the-art techniques. Students construct and operate working apparatus. Topics include microscope optics, Koehler illumination, contrast-generating mechanisms (bright/dark field, fluorescence, phase contrast, differential interference contrast), and resolution limits. Laboratory topics vary by year, but include single-molecule fluorescence, fluorescence resonance energy transfer, confocal microscopy, two-photon microscopy, microendoscopy, and optical trapping. Limited enrollment. Recommended: basic physics, Biology core or equivalent, and consent of instructor.
Terms: Spr | Units: 4

BIO 234: Conservation Biology: A Latin American Perspective (BIO 144, HUMBIO 112)

Principles and application of the science of preserving biological diversity. Conceptually, this course is designed to explore 4 major components relevant to the conservation of biodiversity, as exemplified by the Latin American region. The conceptual frameworks and principles, however, should be generally applicable, and provide insights for all regions of the world, including those of lesser biodiversity. Satisfies Central Menu Area 4 for Bio majors. Prerequisite: BIO 101, or BIO 43 or HUMBIO 2A with consent of instructor. Graduate level students will be expected to conduct a literature research exercise leading to a written paper, addressing a topic of their choosing, derived from any of the themes discussed in class.
Terms: Spr | Units: 3

BIO 245: Ecology and evolution of animal behavior (BIO 145)

Ecological and evolutionary perspectives on animal behavior, with an emphasis on social and collective behavior. This is a project-based course in a lecture/seminar format. Seminars will be based on discussion of journal articles. Independent research projects on the behavior of animals on campus. Prerequisites: Biology or Human Biology core, Biology/ES 30. Recommended: statistics.
Terms: Spr | Units: 3
Instructors: ; Gordon, D. (PI)

BIO 254: Molecular and Cellular Neurobiology (NBIO 254)

For graduate students. Includes lectures for BIO 154. Cellular and molecular mechanisms in the organization and functions of the nervous system. Topics: wiring of the neuronal circuit, synapse structure and synaptic transmission, signal transduction in the nervous system, sensory systems, molecular basis of behavior including learning and memory, molecular pathogenesis of neurological diseases.
Terms: Spr | Units: 3-5

BIO 256: Epigenetics (BIO 156)

Epigenetics is the process by which phenotypes not determined by the DNA sequence are stably inherited in successive cell divisions. Course will cover the molecular mechanisms governing epigenetics, ranging from the discovery of epigenetic phenomena to present-day studies on the role of chromatin, DNA methylation, and RNA in regulating epigenetics processes. Topics include: position effect gene expression, genome regulation, gene silencing & heterochromatin, histone code, DNA methylation & imprinting, epigenetics & disease, and epigenetic-based therapeutics. Prerequisite: BIO41 and BIO42 or consent of instructor, advanced biology course such as Bio104
Terms: Spr | Units: 2
Instructors: ; Gozani, O. (PI); Lee, L. (TA)

BIO 268: Statistical and Machine Learning Methods for Genomics (BIOMEDIN 245, CS 373, GENE 245, STATS 345)

Introduction to statistical and computational methods for genomics. Sample topics include: expectation maximization, hidden Markov model, Markov chain Monte Carlo, ensemble learning, probabilistic graphical models, kernel methods and other modern machine learning paradigms. Rationales and techniques illustrated with existing implementations used in population genetics, disease association, and functional regulatory genomics studies. Instruction includes lectures and discussion of readings from primary literature. Homework and projects require implementing some of the algorithms and using existing toolkits for analysis of genomic datasets.
Terms: Spr | Units: 3

BIO 290: Teaching of Biology

Open to upper-division undergraduates and graduate students. Practical experience in teaching lab biology or serving as an assistant in a lecture course. May be repeated for credit. Prerequisite: consent of instructor.
Terms: Aut, Win, Spr, Sum | Units: 1-5 | Repeatable for credit

BIO 299: Biology PhD Lab Rotation

Limited to first year Biology PhD students. Lab rotations with Biosciences faculty.
Terms: Aut, Win, Spr, Sum | Units: 1-10 | Repeatable for credit

BIO 300X: Out-of-Department Graduate Research

Individual research by arrangement with out-of-department instructors. Master's students: credit for work arranged with out-of-department instructors is restricted to Biology students and requires approved department petition. See http://biohonors.stanford.edu for more information. May be repeated for credit.
Terms: Aut, Win, Spr, Sum | Units: 1-10 | Repeatable for credit
Instructors: ; Andriacchi, T. (PI); Barna, M. (PI); Barres, B. (PI); Behr, B. (PI); Bergmann, D. (PI); Bertozzi, C. (PI); Blau, H. (PI); Block, B. (PI); Block, S. (PI); Boggs, C. (PI); Boothroyd, J. (PI); Brandman, O. (PI); Brown, J. (PI); Brown, P. (PI); Brunet, A. (PI); Brunger, A. (PI); Brutlag, D. (PI); Burgos, T. (PI); Bustamante, C. (PI); Butcher, E. (PI); Butte, A. (PI); Camarillo, D. (PI); Chan, P. (PI); Chen, J. (PI); Cimprich, K. (PI); Clandinin, T. (PI); Cleary, M. (PI); Cochran, J. (PI); Contag, C. (PI); Crabtree, G. (PI); Crowder, L. (PI); Cyert, M. (PI); Daily, G. (PI); Davis, M. (PI); Davis, R. (PI); Demirci, U. (PI); Denny, M. (PI); Diehn, M. (PI); Ding, J. (PI); Dirzo, R. (PI); Du Bois, J. (PI); Ehrhardt, D. (PI); Ehrlich, P. (PI); Eliashberg, Y. (PI); Fathman, C. (PI); Feldman, M. (PI); Felsher, D. (PI); Fernald, R. (PI); Field, C. (PI); Fire, A. (PI); Ford, J. (PI); Fraser, H. (PI); Fredericson, M. (PI); Freyberg, D. (PI); Frommer, W. (PI); Frydman, J. (PI); Fukami, T. (PI); Fuller, M. (PI); Gardner, C. (PI); Garner, C. (PI); Gilly, W. (PI); Gitler, A. (PI); Glenn, J. (PI); Gold, G. (PI); Goodman, M. (PI); Goodman, S. (PI); Gordon, D. (PI); Gozani, O. (PI); Habtezion, A. (PI); Hadly, E. (PI); Hanawalt, P. (PI); Haskell, W. (PI); Heilshorn, S. (PI); Heller, H. (PI); Helms, J. (PI); Herzenberg, L. (PI); Hsu, S. (PI); Jones, P. (PI); Katzenstein, D. (PI); Kay, M. (PI); Khalfan, W. (PI); Khavari, P. (PI); Kim, S. (PI); Klein, R. (PI); Knope, M. (PI); Koong, A. (PI); Kopito, R. (PI); Kornberg, A. (PI); Krams, S. (PI); Kuo, C. (PI); Launer, A. (PI); Lee, P. (PI); Levy, R. (PI); Lin, M. (PI); Long, S. (PI); Longaker, M. (PI); Lowe, C. (PI); Luo, L. (PI); Lyons, D. (PI); MacIver, M. (PI); Maduke, M. (PI); Maldonado, Y. (PI); Malenka, R. (PI); Marinkovich, M. (PI); Matheson, G. (PI); McConnell, S. (PI); Micheli, F. (PI); Mignot, E. (PI); Miklos, D. (PI); Mochly-Rosen, D. (PI); Monack, D. (PI); Montgomery, S. (PI); Mooney, H. (PI); Mordecai, E. (PI); Morris, R. (PI); Morrison, A. (PI); Mudgett, M. (PI); Murphy, G. (PI); Mustapha, M. (PI); Naumovski, L. (PI); Nayak, N. (PI); Nelson, W. (PI); Nishino, S. (PI); Nolan, G. (PI); Nusse, R. (PI); O'Brien, L. (PI); O'hara, R. (PI); Oro, A. (PI); Palmer, T. (PI); Palumbi, S. (PI); Parker, K. (PI); Petrov, D. (PI); Pollack, J. (PI); Pringle, J. (PI); Rando, T. (PI); Raymond, J. (PI); Red-Horse, K. (PI); Reijo Pera, R. (PI); Reimer, R. (PI); Relman, D. (PI); Robinson, B. (PI); Rockson, S. (PI); Rohatgi, R. (PI); Root, T. (PI); Rosenberg, N. (PI); Rothschild, L. (PI); Sage, J. (PI); Salzman, J. (PI); Salzman, Y. (PI); Sapolsky, R. (PI); Scherrer, G. (PI); Schnitzer, M. (PI); Scott, M. (PI); Sebastiano, V. (PI); Shapiro, L. (PI); Shatz, C. (PI); Shen, K. (PI); Sherlock, G. (PI); Shooter, E. (PI); Shrager, J. (PI); Shulman, N. (PI); Sibley, E. (PI); Sikic, B. (PI); Simon, M. (PI); Simoni, R. (PI); Singh, U. (PI); Skirboll, S. (PI); Skotheim, J. (PI); Somero, G. (PI); Sonnenburg, J. (PI); Spormann, A. (PI); Spudich, J. (PI); Stearns, T. (PI); Steinman, L. (PI); Straight, A. (PI); Sudhof, T. (PI); Sun, Z. (PI); Sweet-Cordero (PI); Tan, M. (PI); Theriot, J. (PI); Thompson, S. (PI); Triadafilopoulos, G. (PI); Tsao, P. (PI); Tuljapurkar, S. (PI); Umetsu, D. (PI); Vemuri, M. (PI); Vitousek, P. (PI); Walbot, V. (PI); Watt, W. (PI); Waymouth, R. (PI); Weissman, I. (PI); West, R. (PI); Wong, A. (PI); Wu, J. (PI); Wysocka, J. (PI); Yang, F. (PI); Yang, Y. (PI); Yao, M. (PI); Zarins, C. (PI); Zhao, H. (PI); de Lecea, L. (PI); Collins, J. (GP); Kanagawa, K. (GP); Thompson, J. (GP)

BIO 304: Current Topics and Concepts in Population Biology, Ecology, and Evolution

Required of first-year PhD students in population biology, and ecology and evolution. Major conceptual issues and developing topics. This course isnnopen only to Biology PhD students and is not open to auditors.
Terms: Spr | Units: 1
Instructors: ; Rosenberg, N. (PI)

BIO 342: Plant Biology Seminar

Topics announced at the beginning of each quarter. Current literature. May be repeated for credit. See http://carnegiedpb.stanford.edu/seminars/seminars.php.
Terms: Aut, Win, Spr | Units: 1-3 | Repeatable for credit

BIO 383: Seminar in Population Genetics

Literature review, research, and current problems in the theory and practice of population genetics and molecular evolution. May be repeated for credit. Prerequisite: consent of instructor.
Terms: Aut, Win, Spr | Units: 1-3 | Repeatable for credit

BIO 459: Frontiers in Interdisciplinary Biosciences (BIOC 459, BIOE 459, CHEM 459, CHEMENG 459, PSYCH 459)

Students register through their affiliated department; otherwise register for CHEMENG 459. For specialists and non-specialists. Sponsored by the Stanford BioX Program. Three seminars per quarter address scientific and technical themes related to interdisciplinary approaches in bioengineering, medicine, and the chemical, physical, and biological sciences. Leading investigators from Stanford and the world present breakthroughs and endeavors that cut across core disciplines. Pre-seminars introduce basic concepts and background for non-experts. Registered students attend all pre-seminars; others welcome. See http://biox.stanford.edu/courses/459.html. Recommended: basic mathematics, biology, chemistry, and physics.
Terms: Aut, Win, Spr | Units: 1 | Repeatable for credit
Instructors: ; Robertson, C. (PI)
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