41 - 50 of 71 results for: CHEM

Required of all fourth year Ph.D. students. Students formulate, write, and orally defend an original research proposal.

Advanced synthetic organic chemistry with an emphasis on structure, reactivity, stereocontrol, and named reactions. This course draws from underlying physical organic principles in order to teach students how to analyze complex organic reactions, predict functional group reactivity, propose reasonable reaction mechanisms, and begin to construct multistep syntheses of organic molecules. Topics include: pericyclic reactions, CO, CN, CC, and C=C bond formation, transition metal-catalyzed cross-coupling, radical chemistry, and photochemistry. A solid foundation in organic chemistry is expected.

Physical Organic Chemistry. This course is focused on understanding the important physical principles in organic chemistry, including bonding and structural analysis; molecular interactions; thermodynamics; kinetics; methods to investigate reactive intermediates, reactivity, and elucidate reaction mechanisms. Prerequisite: Chem 123 (formerly 131).

From molecular medicine to molecular anthropology and all sciences in between, chemistry and more generally molecular science are driven by one's understanding of structure and how structure relates to properties, reactivities (mechanisms) and function (e.g. materials, medicines, diagnostics, imaging agents) and by one's ability to design and make molecules. This course integrates the mechanistic and structural foundations of organic chemistry with an emphasis on reactive intermediates, reaction mechanisms and strategies for the design and synthesis of complex molecules. An additional emphasis is placed on generating ideas and proposals directed at identifying and solving problems in science as required for a career in molecular science and for the advancement of science for societal benefit. Special guest lecturers and student presentations will be included.

(Formerly 235) The uses of NMR spectroscopy in chemical and biochemical sciences, emphasizing data acquisition and interpretation for liquid samples and including selection, setup, and processing of standard and advanced experiments.

(Formerly Chem 253) Electronic structure and physical properties of transition metal complexes. Ligand field and molecular orbital theories, magnetism and magnetic susceptibility, electron paramagnetic resonance including hyperfine interactions and zero field splitting and electronic absorption spectroscopy including vibrational interactions. Prerequisite: advanced undergrad-level inorganic course (equivalent to CHEM 153).

Learn how basic concepts in inorganic chemistry can be applied to materials of all dimensionalities. Specific topics will include: symmetry (group theory), bonding models (crystal field theory, valence bond theory, molecular orbital theory, and the Bloch theorem) and electronic structure, and properties/reactivity of molecules and extended solids. Prerequisites: CHEM 151 and either CHEM 173 or CHEM 171 for students who took CHEM 171 in Spring 2021 or later.

Chemical reactions of organotransition metal complexes and their role in homogeneous catalysis. Analogous patterns among reactions of transition metal complexes in lower oxidation states. Physical methods of structure determination. Prerequisite: one year of physical chemistry.

(Formerly Chem 297) Overview of metal sites in biology. Metalloproteins as elaborated inorganic complexes, their basic coordination chemistry and bonding, unique features of the protein ligand, and the physical methods used to study active sites. Active site structures are correlated with function (election transfer; dioxygen binding, activation and reduction to water). Prerequisites: Chem 153 and Chem 173, or equivalents.