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We have come a long way in developing therapies for chronic diseases. However, a gap remains between the current solutions and our ability to fully address these diseases. This course provides an overview of: (1) the underlying biology of many of these diseases and (2) the applications of novel advances in basic science and biotechnology to generate more effective therapies. There will be guest lectures from prominent leaders in academia and industry, and we encourage both students and speakers to seek opportunities to collaborate. No hard prerequisites, though a basic understanding of biology and willingness to learn novel concepts will help.