BIO 86: Cell Biology
This course will focus on the basic structures inside cells and how they execute cellular functions. Topics include organelles, membrane trafficking, the cytoskeleton, cell division, and signal transduction. Classic and recent primary literature will be incorporated into lectures with an emphasis on state of the art experimental approaches. Prerequisites:
BIO 83 is highly recommended.
Terms: Spr
| Units: 4
| UG Reqs: WAY-SMA
Instructors:
Feldman, J. (PI)
;
Khalfan, W. (PI)
;
Shen, K. (PI)
;
Tolby, L. (TA)
;
Varnau, R. (TA)
;
Vollbrecht, M. (TA)
;
Xiong, X. (TA)
;
Yamaya, K. (TA)
BIO 111: Microbiology
Introduction to microbiology, with emphasis on bacteria. Topics include the cell structure of microorganisms, gene regulation, bacterial genetics, bacterial evolution and diversity, bacterial development, interaction and communication, bacterial chemotaxis and motility, microbiomes, infectious diseases, bacterial pathogenesis, host defense systems, and viruses. Strongly recommended: molecular biology, biochemistry, genetics or cell biology courses (e.g.
BIO 82, 83 or 86).
Terms: Win
| Units: 3
Instructors:
Jacobs-Wagner, C. (PI)
BIO 134: Molecular and cellular analysis of human cancer cell lines
This laboratory course will use cultured mammalian cells to study whether drug treatment can restore function to mutant versions of the tumor suppressor p53. Students will perform a variety of cellular and molecular techniques, including RT-PCR and immunofluorescence, to test certain abilities of their mutant in the presence and absence of the drug. The project will culminate with student-designed experiments testing a functional aspect of p53 and presentation of the results for both expert and lay audiences. Strongly suggested prerequisite:
BIO 45,
BIO 82, 83, 86.
Terms: Spr
| Units: 5
Instructors:
Imam, J. (PI)
BIO 139: Pattern Formation
We have all seen patterns in nature: from zebra stripes to spiraling flower petals to ordered rows of microscopic appendages on single celled pond organisms. But how are these patterns generated, what are they good for, and are patterns in different species related? This upper level course in cell and developmental biology will explore how patterns emerge in cells and organisms and through evolution, touching on topics in cell polarity and adhesion, cell differentiation, cell-cell signaling, morphogenesis, and growth control.
BIO 83,
BIO 86 or equivalent; BIO160 or BIO158 recommended.
Terms: Win
| Units: 3
Instructors:
Feldman, J. (PI)
;
Simon, M. (PI)
BIO 158: Developmental Neurobiology (BIO 258)
For advanced undergraduates and coterminal students. The principles of nervous system development from the molecular control of patterning, cell-cell interactions, and trophic factors to the level of neural systems and the role of experience in influencing brain structure and function. Topics: neural induction and patterning cell lineage, neurogenesis, neuronal migration, axonal pathfinding, synapse elimination, the role of activity, critical periods, and the development of behavior. Prerequisites:
BIO 82, 83, 84, 86.
Terms: Aut
| Units: 4
| UG Reqs: WAY-SMA, GER: DB-NatSci
Instructors:
McConnell, S. (PI)
BIO 168: Explorations in Stem Cell Biology
A discussion-based course for advanced undergraduates. The purpose of this course is to introduce students to key topics in stem cell biology and foster the development of strong scientific writing skills. We will review and discuss some landmark and current primary literature in the stem cell field. Topics will include embryonic and adult stem cells, cellular reprogramming and stem cells in disease and regenerative medicine. Students will present a current research paper in their preferred stem cell topic area and compose a novel research proposal. Prerequisites: Biology or Human Biology core or
BIO 82, 83, 86. Satisfies WIM in Biology.
Terms: Aut
| Units: 3
Instructors:
Imam, J. (PI)
BIO 230: Cellular and Molecular Immunology: An Introductory Course (IMMUNOL 200, MI 200)
Mechanisms of immune responses in health and disease. Innate and adaptive immunity; development of the immune system; molecular biology, structure, and function of antibodies and T-cell receptors; cellular basis and regulation of immune responses; infectious diseases and vaccines; allergy, inflammation, and autoimmunity. COVID-19 will be featured as a major example. Lectures and discussion in class and in sections. For upper class undergraduate and graduate students who have not had an introductory immunology course. Prerequisites for undergraduates: Biology Core, Human Biology Core, or
BIO 83 and 86, or consent of instructor. For graduate students: College-level molecular biology, biochemistry, and cell biology, or consent of instructor.
Terms: Aut
| Units: 4
BIO 258: Developmental Neurobiology (BIO 158)
For advanced undergraduates and coterminal students. The principles of nervous system development from the molecular control of patterning, cell-cell interactions, and trophic factors to the level of neural systems and the role of experience in influencing brain structure and function. Topics: neural induction and patterning cell lineage, neurogenesis, neuronal migration, axonal pathfinding, synapse elimination, the role of activity, critical periods, and the development of behavior. Prerequisites:
BIO 82, 83, 84, 86.
Terms: Aut
| Units: 4
Instructors:
McConnell, S. (PI)
IMMUNOL 200: Cellular and Molecular Immunology: An Introductory Course (BIO 230, MI 200)
Mechanisms of immune responses in health and disease. Innate and adaptive immunity; development of the immune system; molecular biology, structure, and function of antibodies and T-cell receptors; cellular basis and regulation of immune responses; infectious diseases and vaccines; allergy, inflammation, and autoimmunity. COVID-19 will be featured as a major example. Lectures and discussion in class and in sections. For upper class undergraduate and graduate students who have not had an introductory immunology course. Prerequisites for undergraduates: Biology Core, Human Biology Core, or
BIO 83 and 86, or consent of instructor. For graduate students: College-level molecular biology, biochemistry, and cell biology, or consent of instructor.
Terms: Aut
| Units: 4
MI 200: Cellular and Molecular Immunology: An Introductory Course (BIO 230, IMMUNOL 200)
Mechanisms of immune responses in health and disease. Innate and adaptive immunity; development of the immune system; molecular biology, structure, and function of antibodies and T-cell receptors; cellular basis and regulation of immune responses; infectious diseases and vaccines; allergy, inflammation, and autoimmunity. COVID-19 will be featured as a major example. Lectures and discussion in class and in sections. For upper class undergraduate and graduate students who have not had an introductory immunology course. Prerequisites for undergraduates: Biology Core, Human Biology Core, or
BIO 83 and 86, or consent of instructor. For graduate students: College-level molecular biology, biochemistry, and cell biology, or consent of instructor.
Terms: Aut
| Units: 4
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