BIOMEDIN 215: Data Driven Medicine
With the spread of electronic health records and increasingly low cost assays for patient molecular data, powerful data repositories with tremendous potential for biomedical research, clinical care and personalized medicine are being built. But these databases are large and difficult for any one specialist to analyze. To find the hidden associations within the full set of data, we introduce methods for datamining at the internet scale, the handling of largescale electronic medical records data for machine learning, methods in natural language processing and textmining applied to medical records, methods for using ontologies for the annotation and indexing of unstructured content as well as semantic web technologies. Prerequisites:
CS 106A;
STATS 216. Recommended: one of
CS 246,
STATS 305, or
CS 22
Terms: Aut

Units: 3

Grading: Medical Option (MedLtrCR/NC)
BIOMEDIN 225: Data Driven Medicine: Lectures
Lectures for
BIOMEDIN 215.With the spread of electronic health records and increasingly low cost assays for patient molecular data, powerful data repositories with tremendous potential for biomedical research, clinical care and personalized medicine are being built. But these databases are large and difficult for any one specialist to analyze. To find the hidden associations within the full set of data, we introduce methods for datamining at the internet scale, the handling of largescale electronic medical records data for machine learning, methods in natural language processing and textmining applied to medical records, methods for using ontologies for the annotation and indexing of unstructured content as well as semantic web technologies. Prerequisites: familiarity with statistics (
STATS 216) and biology.
Terms: Aut

Units: 2

Grading: Medical Option (MedLtrCR/NC)
STATS 216: Introduction to Statistical Learning
Overview of supervised learning, with a focus on regression and classification methods. Syllabus includes: linear and polynomial regression, logistic regression and linear discriminant analysis;crossvalidation and the bootstrap, model selection and regularization methods (ridge and lasso); nonlinear models, splines and generalized additive models; treebased methods, random forests and boosting; supportvector machines; Some unsupervised learning: principal components and clustering (kmeans and hierarchical). Computing is done in R, through tutorial sessions and homework assignments. This mathlight course is offered via video segments (MOOC style), and inclass problem solving sessions. Prereqs: Introductory courses in statistics or probability (e.g.,
Stats 60), linear algebra (e.g.,
Math 51), and computer programming (e.g.,
CS 105).
Terms: Win

Units: 3

Grading: Letter or Credit/No Credit
Instructors:
Tibshirani, R. (PI)
;
Gorham, J. (TA)
;
Miao, J. (TA)
...
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Instructors:
Tibshirani, R. (PI)
;
Gorham, J. (TA)
;
Miao, J. (TA)
;
Powers, S. (TA)
;
Rosenman, E. (TA)
;
Wang, X. (TA)
STATS 216V: Introduction to Statistical Learning
Overview of supervised learning, with a focus on regression and classification methods. Syllabus includes: linear and polynomial regression, logistic regression and linear discriminant analysis; crossvalidation and the bootstrap, model selection and regularization methods (ridge and lasso); nonlinear models, splines and generalized additive models; treebased methods, random forests and boosting; supportvector machines; Some unsupervised learning: principal components and clustering (kmeans and hierarchical). Computing is done in R, through tutorial sessions and homework assignments. This mathlight course is offered remotely only via video segments (MOOC style). TAs will host remote weekly office hours using an online platform such as Google Hangout or BlueJeans. There are four homework assignments, a midterm, and a final exam, all of which are administered remotely. Prereqs: Introductory courses in statistics or probability (e.g.,
Stats 60), linear algebra (e.g.,
Math 51), and computer programming (e.g.,
CS 105).
Terms: Sum

Units: 3

Grading: Letter or Credit/No Credit
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