1 - 6 of 6 results for: BIOS

Mini-course. Covers the fundamentals of major single-molecule manipulation methods (optical tweezers, magnetic tweezers, and atomic force microscopy), principles of force measurement signal and noise, and applications to studies of folding, binding, polymer elasticity, and structural transitions in proteins and nucleic acids. Intended for students with no previous exposure to single-molecule manipulation or for beginning practitioners. Lectures and discussion of current literature.

Mini-course. Students will use learn make and print 3D models of their data to use as a focal point when describing their project. We will teach the students how to use Autocad and Blender to process existing data sets and students are encouraged to bring their own data. We strive to make wearable models to enable instant mini-lectures any place and anytime.

Graduate students in the Biosciences PhD Programs develop a fellowship proposal (e.g. NIH F31) focusing on required documents: 1-page specific aims as well as research and career development plans. Students establish a writing practice and learn fundamental grant writing skills through guided exercises, including in-class review and focused faculty feedback.

In an intensive 1-day format, students learn the fundamentals for writing competitive fellowships, i.e. NIH NRSA fellowships (F30, F31, F32). Topics include developing specific aims; outlining research and career development plans; and using the review criteria to inform writing. Students develop early drafts of the 1-page specific aims, NIH biosketch, and training plan, and receive feedback from instructor. Students are expected to be in the early stages of writing a fellowship proposal.

This course is designed to provide a broad overview of the biology and applications of the revolutionary CRISPR/Cas9 system, with detailed exploration of several areas: / / --Basic biology of the CRISPR/Cas9 system / --High-throughput screening using CRISPR/Cas9 / --Epigenetic modifications and transcriptional regulation using dCas9 / --Therapeutic applications of gene editing with CRISPR / --Disease modeling with CRISPR / --Ethical considerations of the use of CRISPR/Cas9 / / The course will be geared toward advanced undergraduates and graduate students, and will assume a basic background in molecular biology and genetics. The course will be lecture-based, with frequent opportunities for discussion and questions.