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OSPOXFRD 30A: The History and Science of Vaccine Technology

This course is inspired by the ongoing pandemic and the interplay between the complex science of vaccine and drug development, science communication, and public policy. We will discuss the history of vaccines and pandemics/epidemics, the science and engineering of vaccine and therapeutic technologies, the regulatory process for development of novel vaccines and therapeutics, public policy related to medical and non-medical interventions. We will also touch on biotechnology entrepreneurship covering invention, business models, and business partnerships (e.g., BioNTech/Pfizer and Oxford/AstraZeneca). In addition to the infectious disease focus, we will briefly cover how core discoveries in immunology have led to critical advancements in the treatment of cancer and autoimmune disorders. Throughout the course we will discuss how interdisciplinary collaboration is critical in the effective and equitable translation of scientific advancements. The course will be composed of discussions, guest lectures, and field trips integrating the unique local resources. Assignments will include readings, class presentations, individual research projects, and writings.
Terms: Aut | Units: 4-5 | UG Reqs: WAY-SMA
Instructors: Appel, E. (PI)
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