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1 - 10 of 13 results for: CSB ; Currently searching offered courses. You can also include unoffered courses

CSB 230: Current Methods in Proteomics

Introduces students to the instrumentation, experimental strategies, and computational methods used for identification and quantification of protein concentrations and posttranslational modifications on a systems-wide level. Topics include mass spectrometry (instrumentation configurations; polypeptide ionization; sample preparation and fractionation techniques; mass spectra interpretation; relative and absolute protein quantitation; and proteome-scale dataset analysis), protein and antibody arrays, multiparameter flow cytometry with Bayesian analysis, ribosomal protein translation profiling, and GFP and fluorescence imaging based quantification of protein abundance and post-translational modifications.
Terms: Aut | Units: 3 | Grading: Medical Option (Med-Ltr-CR/NC)

CSB 199: Undergraduate Research

Students undertake investigations sponsored by individual faculty members. Prerequisite: consent of instructor.
Terms: Aut, Win, Spr, Sum | Units: 1-18 | Repeatable for credit | Grading: Satisfactory/No Credit

CSB 210: Cell Signalling

The molecular mechanisms through which cells receive and respond to external signals. Emphasis is on principles of cell signaling, the systems-level properties of signal transduction modules, and experimental strategies through which cell signaling pathways are being studied. Prerequisite: working knowledge of biochemistry and genetics.
Terms: Win | Units: 4 | Grading: Letter (ABCD/NP)

CSB 242: Drug Discovery and Development Seminar Series

The scientific principles and technologies involved in making the transition from a basic biological observation to the creation of a new drug emphasizing molecular and genetic issues. Prerequisite: biochemistry, chemistry, or bioengineering.
Terms: Win, Spr | Units: 1 | Repeatable for credit | Grading: Medical Satisfactory/No Credit

CSB 244: Drug Discovery and Development: A Case-based Approach

Introductory course covering the basics of drug discovery and development. Topics include target identification and validation; identification of small molecule compounds that modulate the target of interest; properties of a drug development candidate; drug formulation, absorption, and pharmacokinetics; preclinical safety studies; drug manufacturing and quality assurance; human testing for safety and efficacy; and regulatory issues. Chemical and Systems Biology students may not take this class for credit in addition to CSB 240A.
Terms: Spr | Units: 3 | Grading: Medical Option (Med-Ltr-CR/NC)

CSB 260: Quantitative Chemical Biology

Current topics including protein and small molecule engineering, cell signaling sensors and modulators, molecular imaging, chemical genetics, combinatorial chemistry, in vitro evolution, and signaling network modeling. Prerequisites: undergraduate organic chemistry, and biochemistry or cell biology.
Terms: Spr, alternate years, not given next year | Units: 4 | Grading: Letter or Credit/No Credit
Instructors: Chen, J. (PI)

CSB 270: Research Seminar

Guest speakers and discussion on current research in pharmacology.
Terms: Win | Units: 1 | Repeatable for credit | Grading: Medical Satisfactory/No Credit

CSB 271: Principles of Cell Cycle Control (BIO 171, BIO 271)

Genetic analysis of the key regulatory circuits governing the control of cell division. Illustration of key principles that can be generalized to other synthetic and natural biological circuits. Focus on tractable model organisms; growth control; irreversible biochemical switches; chromosome duplication; mitosis; DNA damage checkpoints; MAPK pathway-cell cycle interface; oncogenesis. Analysis of classic and current primary literature. Satisfies Central Menu Area 2.
Terms: Aut | Units: 3 | Grading: Letter (ABCD/NP)

CSB 299: Directed Reading in Chemical and Systems Biology

Prerequisite: consent of instructor.
Terms: Aut, Win, Spr, Sum | Units: 1-18 | Repeatable for credit | Grading: Medical Satisfactory/No Credit

CSB 370: Medical Scholars Research

Provides an opportunity for student and faculty interaction, as well as academic credit and financial support, to medical students who undertake original research. Enrollment is limited to students with approved projects.
Terms: Aut, Win, Spr, Sum | Units: 4-18 | Repeatable for credit | Grading: Medical School MD Grades
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