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61 - 70 of 83 results for: CHEM

CHEM 275: Advanced Physical Chemistry - Single Molecules and Light

Covers optical single-molecule detection, spectroscopy, and imaging for detection of motional dynamics, super-resolution structure beyond the diffraction limit, and nanoscale interactions and orientations mostly in biological materials. Includes an in-class laboratory component. Recommended: CHEM 271 or PHYSICS 230 and CHEM 273 or equivalent.
Terms: Spr | Units: 3 | Repeatable for credit

CHEM 277: Materials Chemistry and Physics

Topics: structures and symmetries and of solid state crystalline materials, chemical applications of group theory in solids, quantum mechanical electronic band structures of solids, phonons in solids, synthesis methods and characterization techniques for solids including nanostructured materials, selected applications of solid state materials and nanostructures. May be repeated for credit.
Terms: Win | Units: 3 | Repeatable for credit
Instructors: Dai, H. (PI)

CHEM 278B: Research Progress in Physical Chemistry

Required of all second- and third-year Ph.D. candidates in physical and biophysical chemistry and chemical physics. Second-year students present their research progress and plans in brief written and oral summaries (A); third-year students prepare a written progress report (B). A: Win, B: Win
Terms: Win | Units: 1 | Repeatable for credit
Instructors: Cui, B. (PI)

CHEM 279: Chemophysical analyses of costs to lower atmospheric concentrations of greenhouse gases

Many methods have been proposed to reduce future concentration of CO2, CH4 and other greenhouse gases in the atmosphere from stricter emission regulations, to lower carbon energy sources, to more distribution of existing resources over space and time, to atmospheric capture and sequestration of gases already in the atmosphere. All methods would impose costs in some form. What can chemical and physical analyses tell us about the costs of different approaches? In this graduate-level seminar, students will read primary literature examining the chemical and physical challenges and limitations of various approaches and, by rigorous assessment of the theory and data available to date, will seek to estimate a credible range of future costs for each approach. Prerequisite: Previous study of thermodynamics, kinetics and quantum mechanics at the level of Chemistry 171 and 173.
Terms: Spr | Units: 3

CHEM 280: Single-Molecule Spectroscopy and Imaging

Theoretical and experimental techniques necessary to achieve single-molecule sensitivity in laser spectroscopy: interaction of radiation with spectroscopic transitions; systematics of signals, noise, and signal-to-noise; modulation and imaging methods; and analysis of fluctuations; applications to modern problems in biophysics, cellular imaging, physical chemistry, single-photon sources, and materials science. Prerequisites: CHEM 271, previous or concurrent enrollment in CHEM 273.
Last offered: Autumn 2005

CHEM 281: Therapeutic Science at the Chemistry - Biology Interface

(Formerly Chem 227) Explores the design and enablement of new medicines that were born from a convergence of concepts and techniques from chemistry and biology. Topics include an overview of the drug development process, design of of small molecule medicines with various modes of action, drug metabolism and pharmacogenomics, biologic medicines including protein- and nucleic acid-based therapeutics, glycoscience and glycomimetic drugs, and cell-based medicines derived from synthetic biology. Prerequisite: undergraduate level organic chemistry and biochemistry as well as familiarity with concepts in cell and molecular biology.
Terms: Win | Units: 3
Instructors: Bertozzi, C. (PI)

CHEM 283: Synthesis and Analysis at the Chemistry-Biology Interface

(Formerly 226) Focus on the combined use of organic chemistry and molecular biology to make, manipulate and measure biomacromolecules. Synthetic methods for design and construction of peptides, proteins and nucleic acids; methods for bioconjugation and labeling; fluorescence tools; intracellular delivery strategies; combinatorial selection methods. Prerequisite: One year of undergraduate organic chemistry. Completion of a course in molecular biology is strongly recommended.
Terms: Spr | Units: 3
Instructors: Kool, E. (PI)

CHEM 285: Biophysical Chemistry

Primary literature based seminar/discussion course covering classical and contemporary papers in biophysical chemistry. This is intended to provide an introduction to critical analysis of papers in the literature through intensive discussion and evaluation. Topics include (among others): protein structure and stability, folding, single molecule fluorescence and force microscopy, simulations, ion channels, GPCRs, and ribosome structure/function. Course is limited to 15 students and priority will be given to first year Chemistry graduate students.
Last offered: Winter 2019

CHEM 289: Concepts and Applications in Chemical Biology (CSB 260)

Current topics include chemical genetics, activity-based probes, inducible protein degradation, DNA/RNA chemistry and molecular evolution, protein labeling, carbohydrate engineering, fluorescent proteins and sensors, optochemical/optogenetic methods, mass spectrometry, and genome-editing technologies.
Terms: Spr | Units: 3
Instructors: Chen, J. (PI)

CHEM 291: Introduction to Nuclear Magnetic Resonance

Introduction to quantum and classical descriptions of NMR; analysis of pulse sequences and nuclear spin coherences via density matrices and the product operator formalism; NMR spectrometer design; Fourier analysis of time-dependent observable magnetization; NMR relaxation in liquids and solids; NMR strategies for biological problem solving. Prerequisite: Chem 173.
Last offered: Autumn 2013
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