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41 - 50 of 102 results for: BIOE

BIOE 231: Protein Engineering (BIOE 331)

The design and engineering of biomolecules emphasizing proteins, antibodies, and enzymes. Combinatorial and rational methodologies, protein structure and function, and biophysical analyses of modified biomolecules. Clinically relevant examples from the literature and biotech industry. Prerequisite: basic biochemistry. Winter, Cochran
Last offered: Spring 2015

BIOE 236: Biophysical Mechanisms of Innate Immunity

The innate immune system provides our first line of defense against infections of all kinds as well as cancer. Innate immune effectors, e.g. host defense peptides are deployed by numerous cell types (neutrophils, macrophages, NK cells, as well as epithelial cells, keratinocytes, and others) and attack by biophysical mechanisms of action. Disorders of innate immunity are increasingly being implicated in human autoimmune disease. Using primary literature, we will cover the evolution, structures, mechanisms, and functions of innate immune effectors.
Last offered: Spring 2013

BIOE 238: Principles and Tools for Metrology in Biology

A practical introduction to the science of measurement. Emphasis is on the tools used to parse a biological measurement problem. Students will learn to identify and quantitatively address the critical sources of variability and bias using the core concepts of uncertainty, traceability, and validation. Case studies will illustrate use of metrology in current and emergent bioscience and engineering applications.
Terms: Spr | Units: 2

BIOE 241: Biological Macromolecules (BIOC 241, BIOPHYS 241, SBIO 241)

The physical and chemical basis of macromolecular function. Topics include: forces that stabilize macromolecular structure and their complexes; thermodynamics and statistical mechanics of macromolecular folding, binding, and allostery; diffusional processes; kinetics of enzymatic processes; the relationship of these principles to practical application in experimental design and interpretation. The class emphasizes interactive learning, and is divided equally among lectures, in-class group problem solving, and discussion of current and classical literature. Enrollment limited to 50. Prerequisites: Background in biochemistry and physical chemistry recommended but material available for those with deficiency in these areas; undergraduates with consent of instructor only.
Terms: Spr | Units: 3-5


New technologies from gene editing to networked computing have already transformed our economic and social structures and are increasingly changing what it means to be human. What role has law played in regulating and shaping these technologies? And what role can and should it play in the future? This seminar will consider these and related questions, focusing on new forms of networked production, the new landscape of security and scarcity, and the meaning of human nature and ecology in an era of rapid technological change. Readings will be drawn from a range of disciplines, including science and engineering, political economy, and law. The course will feature several guest speakers. There are no formal prerequisites in either engineering or law, but students should be committed to pursuing novel questions in an interdisciplinary context. The enrollment goal is to balance the class composition between law and non-law students. Elements used in grading: Attendance, Class Participation, Written Assignments. CONSENT APPLICATION: To apply for this course, students must complete and submit a Consent Application Form available on the SLS website (Click Courses at the bottom of the homepage and then click Consent of Instructor Forms). See Consent Application Form for instructions and submission deadline. This course is cross-listed with the School of Engineering (TBA). May be repeat for credit
Terms: Win | Units: 2 | Repeatable for credit
Instructors: Endy, D. (PI)

BIOE 244: Advanced Frameworks and Approaches for Engineering Integrated Genetic Systems

Concepts and techniques for the design and implementation of engineered genetic systems. Topics covered include the quantitative exploration of tools that support (a) molecular component engineering, (b) abstraction and composition of functional genetic devices, (c) use of control and dynamical systems theory in device and systems design, (d) treatment of molecular "noise", (e) integration of DNA-encoded programs within cellular chassis, (f) designing for evolution, and (g) the use of standards in measurement, genetic layout architecture, and data exchange. Prerequisites: CME104, CME106, CHEM 33, BIO41, BIO42, BIOE41, BIOE42, and BIOE44 (or equivalents), or permission of the instructors.
Terms: Spr | Units: 4

BIOE 248: Neuroengineering Laboratory (NSUR 248)

Laboratory course exploring the basics of neuroelectrophysiology, neuroengineering, and closed-loop neural decoding. Course will use low-cost electrophysiological amplifying equipment and a real-time recording and computational system to measure neural action potentials from invertebrates, record electromyography from people, and create real-time neural decoders for closed-loop human movement control experiments. Fundamental properties of neurons and systems neuroscience will be experimentally verified. Engineering concepts surrounding neural decoders will be explored. Final project in the course will be a student-conceived in-depth experiment. More information and enrollment instructions are at http://bil.stanford.edu/class.
Terms: Spr | Units: 3

BIOE 253: Science and Technology Policy (PUBLPOL 353)

How U.S. and international political institutions and processes govern science and technology; the roles of scientists, engineers, and physicians in creating and implementing policies; introduction to analytical techniques that are common to research and policy analysis in technology and public policy; and examples from specific mission areas (e.g., economic growth, health, climate, energy and the environment, information technology, international security). Assignments: analyzing the politics of particular legislative outcomes, assessing options for trying to reach a policy objective, and preparing a mock policy memo and congressional testimony.
Last offered: Spring 2015

BIOE 256: Technology Assessment and Regulation of Medical Devices (MS&E 256)

Regulatory approval and reimbursement for new health technologies are critical success factors for product commercialization. This course explores the regulatory and payer environment in the U.S. and abroad, as well as common methods of health technology assessment. Students will learn frameworks to identify factors relevant to the adoption of new health technologies, and the management of those factors in the design and development phases of bringing a product to market through case studies, guest speakers from government (FDA) and industry, and a course project.
Terms: Spr | Units: 3

BIOE 260: Tissue Engineering (ORTHO 260)

Principles of tissue engineering and design strategies for practical applications for tissue repair. Topics include tissue morphogenesis, stem cells, biomaterials, controlled drug and gene delivery, and paper discussions. Students will learn skills for lab research through interactive lectures, paper discussions and research proposal development. Students work in small teams to work on develop research proposal for authentic tissue engineering problems. Lab sessions will teach techniques for culturing cells in 3D, as well as fabricating and characterizing hydrogels as 3D cell niche.
Terms: Spr | Units: 4
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