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BIO 4N: Personalized Genomic Medicine

Exploration of the exciting new field of personalized genomic medicine. Personalized medicine is based on the idea that each person's unique genome sequence can be used to predict risk of acquiring specific diseases, and to make more informed medical choices. Learn about the fascinating science behind these approaches; where they are heading in the future; and the ethical implications such technology presents. Lectures will be augmented with hands-on experience in exploring and analyzing a real person's genome.
Terms: Aut | Units: 3 | UG Reqs: GER: DB-NatSci
Instructors: Fraser, H. (PI)

BIO 15N: Environmental Literacy

Preference to freshmen. Lack of public understanding of the details of most environmental problems is cited as a cause of environmental deterioration. Good citizenship requires literacy about the elements of the scientific and decision making processes that accompany most environmental issues: what can happen, what are the odds, how can the credibility of sources of expertise be assessed, which components of environmental debates deal with factual and theoretical issues, and which are political value judgments?
Terms: Aut | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: Root, T. (PI)

BIO 30N: Extinctions in Near Time: Biodiversity loss since the Pleistocene

The transition 11,700 years ago from the Pleistocene glacial period into the Holocene interglacial witnessed the expansion of humans around the world, climatic warming and the demise of many large vertebrate species. Since that time extinctions have continued on land and in the sea, culminating with the biodiversity crisis we are experiencing today. We will explore these prehistoric extinctions: "Who? When? Where? and Why?" in order to learn more about our planet's future.
Terms: Aut | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-CE, WAY-SMA

BIO 41: Genetics, Biochemistry, and Molecular Biology

Emphasis is on macromolecules (proteins, lipids, carbohydrates, and nucleic acids) and how their structure relates to function and higher order assembly; molecular biology, genome structure and dynamics, gene expression from transcription to translation. Prerequisites: CHEM 31X (or 31A,B), 33. Recommended: CHEM 35; MATH 19, 20, 21 or 41, 42.
Terms: Aut | Units: 5 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIO 101: Ecology

The principles of ecology. Topics: interactions of organisms with their environment, dynamics of populations, species interactions, structure and dynamics of ecological communities, biodiversity. Half-day field trip required. Satisfies Central Menu Area 4. Prerequisite: 43, or consent of instructor. Recommended: statistics.
| UG Reqs: GER: DB-NatSci

BIO 116: Ecology of the Hawaiian Islands (EARTHSYS 116)

Terrestrial and marine ecology and conservation biology of the Hawaiian Archipelago. Taught in the field in Hawaii as part of quarter-long sequence of courses including Earth Sciences and Anthropology. Topics include ecological succession, plant-soil interactions, conservation biology, biological invasions and ecosystem consequences, and coral reef ecology. Restricted to students accepted into the Earth Systems of Hawaii Program.
Terms: Aut | Units: 4 | UG Reqs: GER: DB-NatSci

BIO 147: Controlling Climate Change in the 21st Century (BIO 247, EARTHSYS 147, EARTHSYS 247, HUMBIO 116)

Climate change is a global environmental, social, cultural and economic challenge. Responding to this challenge requires a paradigm shift which will alter energy production, transport, industry, politics, development strategies, north/south equity, and individual freedom and responsibilities around the world. Given the short term planning horizon of the majority of political, economic and social institutions, the slow burn of climate change presents major policy challenges. The course is designed to clarify the primary issues embedded in these challenges.
Terms: Aut | Units: 3 | UG Reqs: GER: DB-NatSci

BIO 154: Molecular and Cellular Neurobiology

For advanced undergraduate students. Cellular and molecular mechanisms in the organization and functions of the nervous system. Topics: wiring of the neuronal circuit, synapse structure and synaptic transmission, signal transduction in the nervous system, sensory systems, molecular basis of behavior including learning and memory, molecular pathogenesis of neurological diseases. Satisfies Central Menu Areas 2 or 3 for Bio majors. Prerequisite for undergraduates: Biology core or equivalent, or consent of instructors.
Terms: Aut | Units: 4 | UG Reqs: GER: DB-NatSci

BIO 188: Biochemistry I (BIO 288, CHEM 181, CHEMENG 181, CHEMENG 281)

(CHEMENG offerings formerly listed as 188/288.) Chemistry of major families of biomolecules including proteins, nucleic acids, carbohydrates, lipids, and cofactors. Structural and mechanistic analysis of properties of proteins including molecular recognition, catalysis, signal transduction, membrane transport, and harvesting of energy from light. Molecular evolution. Satisfies Central Menu Area 1 for Bio majors. Prerequisites: CHEM 33, 35, 131, and 135 or 171.
Terms: Aut | Units: 3 | UG Reqs: GER: DB-NatSci
Instructors: Khosla, C. (PI)

BIOC 158: Genomics, Bioinformatics and Medicine (BIOC 258, BIOMEDIN 258, HUMBIO 158G)

Molecular basis of inherited human disease. Diagnostics approaches: simple Mendelian diseases and complex, multifactorial diseases. Genomics: functional genomics, epigenetics, gene expression, SNPs, copy number and other structural genomic variations involved in disease. Novel therapeutic methods: stem cell therapy, gene therapy and drug developments that depend on the knowledge of genomics. Personal genomics, pharmacogenomics, clinical genomics and their role in the future of preventive medicine. Prerequisites: BIO 41 or HUMBIO 2A or consent of instructor. Those with credit in BIOC 118 not eligible to enroll. Course webpage: http://biochem158.stanford.edu/
Terms: Aut, Win, Spr | Units: 3 | UG Reqs: WAY-SMA, GER: DB-NatSci | Repeatable 2 times (up to 6 units total)
Instructors: Brutlag, D. (PI)
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