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BIO 109A: The Human Genome and Disease (BIOC 109A, BIOC 209A, HUMBIO 158)

The variability of the human genome and the role of genomic information in research, drug discovery, and human health. Concepts and interpretations of genomic markers in medical research and real life applications. Human genomes in diverse populations. Original contributions from thought leaders in academia and industry and interaction between students and guest lecturers. Students with a major, minor or coterm in Biology: 109A/209A or 109B/209B may count toward degree program but not both.
Terms: Win | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIO 109B: The Human Genome and Disease: Genetic Diversity and Personalized Medicine (BIOC 109B)

Continuation of 109A/209A. Genetic drift: the path of human predecessors out of Africa to Europe and then either through Asia to Australia or through northern Russia to Alaska down to the W. Coast of the Americas. Support for this idea through the histocompatibility genes and genetic sequences that predispose people to diseases. Guest lectures from academia and pharmaceutical companies. Prerequisite: Biology or Human Biology core. Students with a major, minor or coterm in Biology: 109A/209A or 109B/209B may count toward degree program but not both.
Terms: Spr | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIO 110: Chromatin Regulation of the Genome (BIO 210)

Maintenance of the genome is a prerequisite for life. In eukaryotes, all DNA-templated processes are tightly connected to chromatin structure and function. This course will explore epigenetic and chromatin regulation of cellular processes related to aging, cancer, stem cell pluripotency, metabolic homeostasis, and development. Course material integrates current literature with a foundational review of histone modifications and nucleosome composition in epigenetic inheritance, transcription, replication, cell division and DNA damage responses. Prerequisite: BIO 41 or consent of instructor.
Terms: Aut | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIO 115: The Hidden Kingdom - Evolution, Ecology and Diversity of Fungi (BIO 239)

Fungi are critical, yet often hidden, components of the biosphere. They regulate decomposition, are primary partners in plant symbiosis and strongly impact agriculture and economics. Students will explore the fascinating world of fungal biology, ecology and evolution via lecture, lab, field exercises and Saturday field trips that will provide traditional and molecular experiences in the collection, analysis and industrial use of diverse fungi. Students will chose an environmental niche, collect and identify resident fungi, and hypothesize about their community relationship. Prerequisite: Bio 43 recommended.
Last offered: Winter 2016 | UG Reqs: WAY-SMA

BIO 117: Biology and Global Change (EARTHSYS 111, ESS 111)

The biological causes and consequences of anthropogenic and natural changes in the atmosphere, oceans, and terrestrial and freshwater ecosystems. Topics: glacial cycles and marine circulation, greenhouse gases and climate change, tropical deforestation and species extinctions, and human population growth and resource use. Prerequisite: Biology or Human Biology core or graduate standing.
Terms: Win | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIO 118: Genetic Analysis of Biological Processes

Focus is on using mutations and genetic analysis to study biological and medical questions. The first portion of the course covers how the identification and analysis of mutations can be used in model systems to investigate biological processes such as development and metabolism. In the second portion of the course, we focus on the use of existing genetic variation in humans and other species to identify disease-associated genes as well as to investigate variation in morphological traits such as body size and shape.
Terms: Aut | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIO 137: Plant Genetics

Gene analysis, mutagenesis, transposable elements; developmental genetics of flowering and embryo development; biochemical genetics of plant metabolism; scientific and societal lessons from transgenic plants. Satisfies Central Menu Area 2. Prerequisite: Biology core or consent of instructor. Satisfies WIM in Biology.
Terms: Spr | Units: 3-4 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIO 150: Human Behavioral Biology (HUMBIO 160)

Multidisciplinary. How to approach complex normal and abnormal behaviors through biology. How to integrate disciplines including sociobiology, ethology, neuroscience, and endocrinology to examine behaviors such as aggression, sexual behavior, language use, and mental illness.
Last offered: Spring 2016 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIO 153: Cellular Neuroscience: Cell Signaling and Behavior (PSYCH 120)

Neural interactions underlying behavior. Prerequisites: PSYCH 1 or basic biology.
Terms: Aut | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIO 158: Developmental Neurobiology (BIO 258)

For advanced undergraduates and coterminal students. The principles of nervous system development from the molecular control of patterning, cell-cell interactions, and trophic factors to the level of neural systems and the role of experience in influencing brain structure and function. Topics: neural induction and patterning cell lineage, neurogenesis, neuronal migration, axonal pathfinding, synapse elimination, the role of activity, critical periods, and the development of behavior. Satisfies Central Menu Areas 2 or 3. Prerequisite: BIO 42 or equivalent.
Terms: Aut | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-SMA
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