printer friendly pageBIO 4N: The Science and Ethics of Personalized Genomic Medicine
We will explore the exciting field of personalized genomic medicine. Personalized medicine is based on the idea that each person's unique genome sequence can be used to predict their risk of developing diseases, and could perhaps even be edited using CRISPR to improve health. We will discuss the science behind these approaches; where they are heading in the future; and the ethical implications such technology presents. Student presentations will be emphasized, and students will also get to explore and analyze a real person's genome.
Terms: Win
| Units: 3
| UG Reqs: GER: DB-NatSci
Instructors:
Fraser, H. (PI)
BIO 7N: Conservation Photography
Introduction to the field of conservation photography and the strategic use of visual communication in addressing issues concerning the environment and conservation. Students will be introduced to basic digital photography, digital image processing, and the theory and application of photographic techniques. Case studies of conservation issues will be examined through photographs and multimedia platforms including images, video, and audio. Lectures, tutorials, demonstrations, and optional field trips will culminate in the production of individual and group projects. Cardinal Course certified by the Haas Center for Public Service.
Terms: Win
| Units: 3
| UG Reqs: WAY-CE
Instructors:
McConnell, S. (PI)
BIO 23Q: Cancer: Biology, History, and Therapy
Cancer is the second leading cause of death in the United States and most families will be affected by it at some point in their lives. Cancer has been known for millennia, but research developments in the last century - and last decade - have dramatically improved the cancer treatment landscape. In this course, we will explore the biology of how cancer works, its history, and traditional and cutting-edge therapies that have been developed to treat cancer.
Terms: Win
| Units: 3
| UG Reqs: WAY-SMA
Instructors:
Armenta, D. (PI)
BIO 25Q: Cystic fibrosis: from medical conundrum to precision medicine success story
The class will explore cystic fibrosis (CF), the most prevalent fatal genetic disease in the US, as a scientific and medical whodunit. Through reading and discussion of medical and scientific literature, we will tackle questions that include: how was life expectancy with CF increased from weeks to decades without understanding the disease mechanism? Why is the disease so prevalent? Is there an advantage to being a carrier? Is CF a single disease or a continuum of physiological variation; or- what is a disease? How did research into CF lead to discovery of the underlying cause of most other genetic diseases as well? Through critical reading of the scientific and medical literature, class discussion, field trips and meetings with genetic counselors, caregivers, patients, physicians and researchers, we will work to build a deep understanding of this disease, from the biochemical basis to the current controversies over pathogenic mechanisms, treatment strategies and the ethics and economics of genetic testing and astronomical drug costs.
Terms: Win
| Units: 3
| UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors:
Kopito, R. (PI)
BIO 35N: Catching up with Traditional Ecological Knowledge
Traditional ecological knowledge--the knowledge developed and maintained by local communities over many generations about their natural environment--is increasingly recognized as fundamental to solving environmental problems. In this seminar, we will explore some of the cutting-edge research on traditional ecological knowledge and its conceptual and practical role in ensuring environmental sustainability. We will address some key questions. For example, what makes traditional ecological knowledge different from Western science? What led to the recent increase in Western scientists' appreciation of traditional ecological knowledge? How can traditional ecological knowledge inform environmental sustainability in a world that is undergoing rapid climate change, land use change, and biological invasion? And how can Western science complement traditional ecological knowledge to achieve sustainability? The core of this seminar will be discussion based on reading of primary articles. We will also have field trips and learn from guest speakers.
Terms: Win
| Units: 3
| UG Reqs: WAY-SMA
Instructors:
Fukami, T. (PI)
BIO 45: Introduction to Laboratory Research in Cell and Molecular Biology
Use modern molecular approaches to characterize a particular tumor-associated mutation in the human p53 tumor suppressor gene via expression and analysis in a yeast model system. Learn about the role of p53 as Guardian of the Genome and consider novel p53-directed tumor therapies through lectures and by reading and discussing journal articles. Use molecular visualization programs to examine the structure of the normal p53 protein and localize the alteration induced by the mutation you are investigating. Assay the ability of mutant p53 to activate expression of multiple reporter genes. Through facilitated discussions with teams of other students studying the same p53 mutant, consider a series of molecular explanations for your p53 mutant's functional defects. Conduct lab experiments to test these hypotheses, analyze data, collaboratively interpret these data, and present your findings through a team oral presentation, as well as a scientific poster. Attendance at both the lecture and la
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Use modern molecular approaches to characterize a particular tumor-associated mutation in the human p53 tumor suppressor gene via expression and analysis in a yeast model system. Learn about the role of p53 as Guardian of the Genome and consider novel p53-directed tumor therapies through lectures and by reading and discussing journal articles. Use molecular visualization programs to examine the structure of the normal p53 protein and localize the alteration induced by the mutation you are investigating. Assay the ability of mutant p53 to activate expression of multiple reporter genes. Through facilitated discussions with teams of other students studying the same p53 mutant, consider a series of molecular explanations for your p53 mutant's functional defects. Conduct lab experiments to test these hypotheses, analyze data, collaboratively interpret these data, and present your findings through a team oral presentation, as well as a scientific poster. Attendance at both the lecture and lab sections is mandatory, and students may only attend the lecture and lab sections in which they are enrolled. Please contact Dr. Shyamala Malladi (smalladi@stanford.edu) if you have any questions about the class. Please note that enrollment is handled by Axess, so enrollment in one pair of BIO45 lecture/lab sections will not give a student any priority for subsequently enrolling in a different pair of lecture/lab sections. Although there are no pre-requisites to enroll in this class, it will be helpful if you have already taken or are concurrently enrolled in introductory courses in cell and molecular biology (
BIO 82 and 83 or
HUMBIO 2A and 3A) and general chemistry (
CHEM 31A and 31B or
CHEM 31E).
Terms: Aut, Win
| Units: 4
Instructors:
Cyert, M. (PI)
;
Hekmat-Scafe, D. (PI)
;
Malladi, S. (PI)
...
more instructors for BIO 45 »
Instructors:
Cyert, M. (PI)
;
Hekmat-Scafe, D. (PI)
;
Malladi, S. (PI)
;
Bolle, C. (TA)
;
Floranda, E. (TA)
;
Jung, Y. (TA)
;
Pont, O. (TA)
;
Sangare, A. (TA)
BIO 46: Introduction to Research in Ecology and Evolutionary Biology (EARTHSYS 46)
The goal of this course is to develop an understanding of how to conduct biological research, using topics in Ecology as practical examples. This includes the complete scientific process: assessing background literature, generating testable hypotheses, learning techniques for data collection, analyzing data using appropriate statistical methods and writing and sharing results. Students, working in teams, develop novel research hypotheses and execute the necessary experiments and measurements to test these hypotheses. In addition, students will learn how to manipulate, visualize, and analyze data in the statistical programming language R. The capstone of the course is a research paper in the style of a peer-reviewed journal article, as well as a group presentation designed for a general audience that communicates research findings. The Tuesday lecture session will generally meet for only about 60-70 minutes. IMPORTANT NOTE: Students who require
BIO 46 to satisfy the WIM requirement for the Biology major MUST take this course for a letter grade. Please contact Amanda Wu (ytwu@stanford.edu) for logistical and enrollment questions.
Terms: Win
| Units: 4
| UG Reqs: WAY-SMA
Instructors:
WU, A. (PI)
BIO 71: Planet Ocean (ESS 71, OCEANS 71)
Oceans make up the majority of our planet's area and living spaces and are fundamental to biodiversity, climate, food and commerce.This course covers integration of the oceanography, marine biology, policy and problem-solving for diverse ocean habitats such as the deep sea, coral reefs, open ocean, temperate coasts, and polar seas. Lectures include state of the art science of these areas, emerging technologies, policies for management and possible solutions to current problems. Discussion sections include how to read and interpret scientific papers, how to frame policy questions using science guidance, new technologies, and how to frame a pitch for a new solution to a current ocean problem.
Terms: Win
| Units: 4
| UG Reqs: WAY-SMA
Instructors:
Dunbar, R. (PI)
;
Micheli, F. (PI)
;
Palumbi, S. (PI)
...
more instructors for BIO 71 »
Instructors:
Dunbar, R. (PI)
;
Micheli, F. (PI)
;
Palumbi, S. (PI)
;
Illing, M. (TA)
;
Olivero, A. (TA)
BIO 82: Genetics
The focus of the course is on the basic mechanisms underlying the transmission of genetic information and on the use of genetic analysis to study biological and medical questions. Major topics will include: (1) the use of existing genetic variation in humans and other species to identify genes that play an important role in determining traits and disease-susceptibility, (2) the analysis of mutations in model organisms and their use in the investigation of biological processes and questions and (3) using genetic information for diagnosis and the potential for genetic manipulations to treat disease. Prerequisites: None, but
BIO 83 is recommended. Lecture attendance as well as discussion section attendance is mandatory. Please only enroll in the lecture section (section 01) on Axess. Discussion section enrollment will be handled on Canvas. As long as you sign up for the lecture section on Axess, you will receive an e-mail a week before classes begin to guide you on how to sign up for a section on Canvas. For logistical questions about the course, please contact Waheeda Khalfan (wkhalfan@stanford.edu).
Terms: Win
| Units: 4
| UG Reqs: WAY-SMA
BIO 84: Physiology
The focus of Physiology is on understanding how organisms tackle the physical challenges of life on Earth. This course will provide an overview of animal and plant physiology and teach an understanding of how organisms maintain homeostasis, respond to environmental cues, and coordinate behaviors across multiple tissues and organ systems. We will examine the structure and function of organs and organ systems and how those systems are controlled and regulated to maintain homeostasis. Control and regulation requires information as does the ability to respond to environmental stimuli, so we will give special consideration to hormonal and neural information systems. We will also be concerned with the interactions and integration of the activities of the different organ systems we study. Prerequisites: none. Lecture attendance as well as discussion section attendance is mandatory. Please only enroll in the lecture section (section 01) on Axess. Discussion section enrollment will be handled on Canvas. As long as you sign up for the lecture section on Axess, you will receive an e-mail a week before classes begin to guide you on how to sign up for a section on Canvas. For logistical questions about the course, please contact Waheeda Khalfan at wkhalfan@stanford.edu.
Terms: Win
| Units: 4
| UG Reqs: WAY-SMA
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