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1 - 10 of 31 results for: GENE

GENE 199: Undergraduate Research

Students undertake investigations sponsored by individual faculty members. Prerequisite: consent of instructor.
Terms: Aut, Win, Spr, Sum | Units: 1-18 | Repeatable for credit

GENE 202: Human Genetics

Utilizes lectures and small group activities to develop a working knowlege of human genetics as applicable to clinical medicine. Basic principles of inheritance, risk assessment, and population genetics are illustrated using examples drawn from diverse areas of medical genetics practice including prenatal, pediatric, adult and cancer genetics. Practical aspects of molecular and cytogenetic diagnostic methods are emphasized. Existing and emerging treatment strategies for single gene disorders are also covered. Prerequisites: basic genetics. Only available to MD and MOM students.
Terms: Aut | Units: 4

GENE 208: Gut Microbiota in Health and Disease (BIOE 221G, MI 221)

Preference to graduate students. Focus is on the human gut microbiota. Students will receive instruction on computational approaches to analyze microbiome data and must complete a related project.
Terms: Aut | Units: 3

GENE 213: AI, Genes and Ethics

What is AI and why is it sometimes biased ? How will AI affect medicine to help us but also what are theconditions in which it may harm us. 95% of single-gene diseases we know of have no effective treatmentyet if we change a defective one how might that affect a species in the long term ? Is DNA ¿the code of life¿?Or is the ¿code of life¿ the whole living organism in its complex, dynamic relationship with itsenvironment? Will Earth one day be populated by beings who are different from us in their cognitiveand physical abilities. This course will look at the intersection of AI and Genetics to analyze advancesthat could be made but also ethical questions that should be asked. The course is designed to beaccessible to many disciplines and there are no pre-requisites.
Terms: Aut | Units: 2-3 | Repeatable 6 times (up to 6 units total)

GENE 214: Representations and Algorithms for Computational Molecular Biology (BIOE 214, BIOMEDIN 214, CS 274)

Topics: This is a graduate level introduction to bioinformatics and computational biology, algorithms for alignment of biological sequences and structures, computing with strings, phylogenetic tree construction, hidden Markov models, basic structural computations on proteins, protein structure prediction, molecular dynamics and energy minimization, statistical analysis of 3D biological data, integration of data sources, knowledge representation and controlled terminologies for molecular biology, microarray analysis, chemoinformatics, pharmacogenetics, network biology. Note: For Fall 2021, Dr. Altman will be away on sabbatical and so class will be taught from lecture videos recorded in fall of 2018. The class will be entirely online, with no scheduled meeting times. Lectures will be released in batches to encourage pacing. A team of TAs will manage all class logistics and grading. Firm prerequisite: CS 106B.
Terms: Aut | Units: 3-4

GENE 215: Frontiers in Biological Research (BIOC 215, DBIO 215)

Students analyze cutting edge science, develop a logical framework for evaluating evidence and models, and enhance their ability to design original research through exposure to experimental tools and strategies. The class runs in parallel with the Frontiers in Biological Research seminar series. Students and faculty meet on the Tuesday preceding each seminar to discuss a landmark paper in the speaker's field of research. Following the Wednesday seminar, students meet briefly with the speaker for a free-range discussion which can include insights into the speakers' paths into science and how they pick scientific problems.
Terms: Aut, Win, Spr | Units: 1 | Repeatable 3 times (up to 3 units total)

GENE 219: Current Issues in Genetics

Current Issues in Genetics is an in-house seminar series that meets each Academic Quarter for one hour per week (Friday, 4:00-5:00) and features talks by Genetics Department faculty, students, and postdoctoral fellows (with occasional visiting speakers). Thus, over the year, it provides a comprehensive overview of the work going on in the Department. First-year Ph.D. students in Genetics are required to enroll during all four Quarters, and students from other programs may be permitted to enroll with prior permission of the instructors.
Terms: Aut, Win, Spr, Sum | Units: 1 | Repeatable 12 times (up to 12 units total)

GENE 224: Principles of Pharmacogenomics (BIOMEDIN 224)

This course is an introduction to pharmacogenomics, including the relevant pharmacology, genomics, experimental methods (sequencing, expression, genotyping), data analysis methods and bioinformatics. The course reviews key gene classes (e.g., cytochromes, transporters) and key drugs (e.g., warfarin, clopidogrel, statins, cancer drugs) in the field. Resources for pharmacogenomics (e.g., PharmGKB, Drugbank, NCBI resources) are reviewed, as well as issues implementing pharmacogenomics testing in the clinical setting. Reading of key papers, including student presentations of this work; problem sets; final project selected with approval of instructor. Prerequisites: two of BIO 41, 42, 43, 44X, 44Y or consent of instructor.
Terms: Aut, Win, Spr, Sum | Units: 3

GENE 260: Supervised Study

Genetics graduate student lab research from first quarter to filing of candidacy. Prerequisite: consent of instructor.
Terms: Aut, Win, Spr, Sum | Units: 1-18 | Repeatable for credit
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