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IMMUNOL 199: Undergraduate Research

Presentations and discussions focus on how current research has progressed from the classic findings in Immunology. This third course in the Immunology core curriculum develops effective presentation skills that are appropriate for a given audience and situation. Students will gain experience in developing and presenting chalk talks, formal presentations, and the all-important elevator pitch on current research. Students will benefit from peer, TA and instructor feedback on all presentations.
Terms: Aut, Win, Spr, Sum | Units: 1-18 | Repeatable for credit
Instructors: Alizadeh, A. (PI) ; Arvin, A. (PI) ; Bendall, S. (PI) ; Blish, C. (PI) ; Bollyky, P. (PI) ; Boothroyd, J. (PI) ; Boyd, S. (PI) ; Butcher, E. (PI) ; Butte, A. (PI) ; Butte, M. (PI) ; Chen, C. (PI) ; Chien, Y. (PI) ; Chu, G. (PI) ; Cleary, M. (PI) ; Contag, C. (PI) ; Crabtree, G. (PI) ; Davis, M. (PI) ; Dhabhar, F. (PI) ; Engleman, E. (PI) ; Fathman, C. (PI) ; Felsher, D. (PI) ; Fire, A. (PI) ; Fontaine, M. (PI) ; Galli, S. (PI) ; Garcia, C. (PI) ; Goronzy, J. (PI) ; Habtezion, A. (PI) ; Han, M. (PI) ; Herzenberg, L. (PI) ; Herzenberg, L. (PI) ; Hsieh, M. (PI) ; Idoyaga, J. (PI) ; Jardetzky, T. (PI) ; Jones, P. (PI) ; Khatri, P. (PI) ; Kim, P. (PI) ; Kirkegaard, K. (PI) ; Kohrt, H. (PI) ; Krams, S. (PI) ; Kuo, C. (PI) ; Lee, P. (PI) ; Levy, R. (PI) ; Levy, S. (PI) ; Lewis, D. (PI) ; Lewis, R. (PI) ; Mackall, C. (PI) ; Maecker, H. (PI) ; Majeti, R. (PI) ; Mallick, P. (PI) ; Martinez, O. (PI) ; McDevitt, H. (PI) ; Mellins, E. (PI) ; Meyer, E. (PI) ; Michie, S. (PI) ; Mignot, E. (PI) ; Miklos, D. (PI) ; Monack, D. (PI) ; Nadeau, K. (PI) ; Nayak, J. (PI) ; Negrin, R. (PI) ; Nicolls, M. (PI) ; Nolan, G. (PI) ; Palmer, T. (PI) ; Parham, P. (PI) ; Quake, S. (PI) ; Robinson, B. (PI) ; Roncarolo, M. (PI) ; Sarwal, M. (PI) ; Schneider, D. (PI) ; Shafer, R. (PI) ; Shizuru, J. (PI) ; Snyder, M. (PI) ; Sobel, R. (PI) ; Steinman, L. (PI) ; Strober, S. (PI) ; Sunwoo, J. (PI) ; Utz, P. (PI) ; Weissman, I. (PI) ; Weyand, C. (PI) ; Winslow, M. (PI) ; Wu, J. (PI) ; Wu, J. (PI) ; Wyss-Coray, T. (PI)

IMMUNOL 201: Advanced Immunology I

For graduate students, medical students and undergraduates. Topics include the innate and adaptive immune systems; genetics and function of immune cells and molecules; lymphocyte activation and regulation of immune responses. Recommended: undergraduate course in immunology.
Terms: Win | Units: 3
Instructors: Chien, Y. (PI) ; Chan, C. (SI)

IMMUNOL 202: Advanced Immunology II

Readings of immunological literature. Classic problems and emerging areas based on primary literature. Student and faculty presentations. Prerequisite: IMMUNOL 201/ MI 211.
Terms: Spr | Units: 3
Instructors: Blish, C. (PI) ; Wang, T. (PI)

IMMUNOL 203: Advanced Immunology III

Key experiments and papers in immunology. Course focuses on the history of Immunology and how current research fits into the historical context. Students work on developing effective presentation skills.
Terms: Sum | Units: 3
Instructors: Krams, S. (PI)

IMMUNOL 205: Immunology in Health and Disease

Concepts and application of adaptive and innate immunology and the role of the immune system in human diseases. Case presentations of diseases including autoimmune diseases, infectious disease and vaccination, hematopoietic and solid organ transplantation, cancer immunotherapy, genetic and acquired immunodeficiencies, hypersensitivity reactions, and allergic diseases. Problem sets based on lectures and current clinical literature. Laboratory in acute and chronic inflammation.
Terms: Win | Units: 4
Instructors: Lewis, D. (PI) ; Aalipour, A. (TA) ; Keyes, T. (TA) ; Smith, B. (TA)

IMMUNOL 206: Introduction to Applied Computational Tools in Immunology

Introduction to computational tools for analyses of immunological data sets, including but not limited to single-cell data such as that from flow cytometry or CyTOF, Luminex, and genomic analyses. Students become familiar with major web-based databases and analysis suites for immunological and genomic data; gain a working knowledge of the major software/algorithms for working with major data types, and be able to apply at least one computational tool in these areas to analyze a public data set. Lectures will be followed by a demonstration and interaction session on the topic. Students will complete a computational analysis project and present it to the class.
Terms: Win | Units: 2
Instructors: Andorf, S. (PI) ; Maecker, H. (PI) ; Andorf, S. (SI)

IMMUNOL 207: Essential Methods in Computational and Systems Immunology

Introduction to the major underpinnings of systems immunology: first principles of development of computational approaches to immunological questions and research; details of the algorithms and statistical principles underlying commonly used tools; aspects of study design and analysis of data sets. Prerequisites: CS106a and CS161 strongly recommended.
Terms: Spr | Units: 3
Instructors: Gentles, A. (PI) ; Khatri, P. (PI)

IMMUNOL 209: Translational Immunology

Open to medical students (regardless of whether they are in foundations or applications), graduate students, and undergraduates (by consent of instructor). The format is a seminar series with weekly lectures from Immunology Faculty and guest speakers focusing on current basic immunology research and how it is translated into immunotherapies and clinical trials. Topics include hematopoiesis, transplantation, tolerance, immune monitoring, vaccination, autoimmunity and antibodies, rheumatoid arthritis, chronic pulmonary disease, and asthma. Med students in the immunology concentration major are allowed to take Imm 209 repeatedly for credit.
Terms: Win, Spr | Units: 1 | Repeatable for credit
Instructors: Bollyky, P. (PI)

IMMUNOL 210: Immunology Research Seminars for Medical Students

Required for medical students selecting the Immunology Concentration. Attendance at a minimum of ten seminars related to immunology outside of required medical school classes. A one-page essay on each seminar, what was presented and how it relates to a clinical immunologic problem, is required.
Terms: Aut, Win, Spr | Units: 2 | Repeatable for credit
Instructors: Bollyky, P. (PI)

IMMUNOL 275: Tumor Immunology (CBIO 275)

Tumor Immunology focuses on the mechanisms by which tumors can escape from and subvert the immune system and conversely on the ability of innate and adaptive arms of the immune system to recognize and eliminate tumors. Topics include: tumor antigens, tumor immunosurveillance and immunoediting, tumor immunotherapy (including CAR-T and checkpoint antibodies) and cancer vaccines. Tracks the historical development of our understanding of modulating tumor immune response and discusses their relative significance in the light of current reserach findings. Prerequisite: for undergraduates, human biology or biology core.
Terms: Spr | Units: 3
Instructors: Engleman, E. (PI) ; Martins, M. (TA) ; Muselman, A. (TA) ; Silberstein, J. (TA)
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