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BIO 83: Biochemistry & Molecular Biology

Introduction to the molecular and biochemical basis of life. Lecture topics include the structure and function of proteins, nucleic acids, lipids and carbohydrates, energy metabolism, signal transduction, epigenetics and DNA repair. The course will also consider how defects in these processes cause disease. Prerequisites: None.
Terms: Win | Units: 4 | UG Reqs: WAY-SMA

BIO 84: Physiology

The fundamental concepts and systems of animal and plant physiology are the subject matter of this course. Prerequisites: None.
Terms: Win | Units: 4 | UG Reqs: WAY-SMA

BIO 86: Cell Biology

This course will focus on the basic structures inside cells and how they execute cellular functions. Topics include organelles, membrane trafficking, the cytoskeleton, cell division, and signal transduction. Classic and recent primary literature will be incorporated into lectures with an emphasis on state of the art experimental approaches. Prerequisites: None.
Terms: Spr | Units: 4 | UG Reqs: WAY-SMA

BIO 109A: The Human Genome and Disease (BIOC 109A, BIOC 209A, HUMBIO 158)

The variability of the human genome and the role of genomic information in research, drug discovery, and human health. Concepts and interpretations of genomic markers in medical research and real life applications. Human genomes in diverse populations. Original contributions from thought leaders in academia and industry and interaction between students and guest lecturers. Students with a major, minor or coterm in Biology: 109A/209A or 109B/209B may count toward degree program but not both.
Terms: Win | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIO 109B: The Human Genome and Disease: Genetic Diversity and Personalized Medicine (BIOC 109B)

Continuation of 109A/209A. Genetic drift: the path of human predecessors out of Africa to Europe and then either through Asia to Australia or through northern Russia to Alaska down to the W. Coast of the Americas. Support for this idea through the histocompatibility genes and genetic sequences that predispose people to diseases. Guest lectures from academia and pharmaceutical companies. Prerequisite: Biology or Human Biology core. Students with a major, minor or coterm in Biology: 109A/209A or 109B/209B may count toward degree program but not both.
Terms: Spr | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIO 110: Chromatin Regulation of the Genome (BIO 210)

Maintenance of the genome is a prerequisite for life. In eukaryotes, all DNA-templated processes are tightly connected to chromatin structure and function. This course will explore epigenetic and chromatin regulation of cellular processes related to aging, cancer, stem cell pluripotency, metabolic homeostasis, and development. Course material integrates current literature with a foundational review of histone modifications and nucleosome composition in epigenetic inheritance, transcription, replication, cell division and DNA damage responses. Prerequisite: BIO 41 or consent of instructor.
Terms: Spr | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIO 112: Human Physiology (HUMBIO 133)

Human physiology will be examined by organ systems: cardiovascular, respiratory, renal, gastrointestinal and endocrine. Molecular and cell biology and signaling principles that underlie organ development, pathophysiology and opportunities for regenerative medicine are discussed, as well as integrative control mechanisms and fetal development. Prerequisite: Human Biology core, Biology core, or equivalent, or consent of instructor.
Terms: Win | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIO 115: The Hidden Kingdom - Evolution, Ecology and Diversity of Fungi (BIO 239)

Fungi are critical, yet often hidden, components of the biosphere. They regulate decomposition, are primary partners in plant symbiosis and strongly impact agriculture and economics. Students will explore the fascinating world of fungal biology, ecology and evolution via lecture, lab, field exercises and Saturday field trips that will provide traditional and molecular experiences in the collection, analysis and industrial use of diverse fungi. Students will chose an environmental niche, collect and identify resident fungi, and hypothesize about their community relationship. Prerequisite: Bio 43 recommended.
Terms: Win | Units: 4 | UG Reqs: WAY-SMA

BIO 117: Biology and Global Change (EARTHSYS 111, ESS 111)

The biological causes and consequences of anthropogenic and natural changes in the atmosphere, oceans, and terrestrial and freshwater ecosystems. Topics: glacial cycles and marine circulation, greenhouse gases and climate change, tropical deforestation and species extinctions, and human population growth and resource use. Prerequisite: Biology or Human Biology core or graduate standing.
Terms: Win | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIO 118: Genetic Analysis of Biological Processes

Focus is on using mutations and genetic analysis to study biological and medical questions. The first portion of the course covers how the identification and analysis of mutations can be used in model systems to investigate biological processes such as development and metabolism. In the second portion of the course, we focus on the use of existing genetic variation in humans and other species to identify disease-associated genes as well as to investigate variation in morphological traits such as body size and shape. This course will be offered for a final time in Winter 2017-18 and then discontinued. Students who have taken BIO 82 may not enroll in BIO 118.
Terms: Win | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-SMA
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