printer friendly pageBIOE 102: Physical Biology of Macromolecules
Principles of statistical physics, thermodynamics, and kinetics with applications to molecular biology. Topics include entropy, temperature, chemical forces, enzyme kinetics, free energy and its uses, self assembly, cooperative transitions in macromolecules, molecular machines, feedback, and accurate replication. Prerequisites:
MATH 19, 20, 21;
CHEM 31A, B (or 31X); strongly recommended:
PHYSICS 41,
CME 100 or
MATH 51, and
CME 106; or instructor approval.
Last offered: Winter 2019
| UG Reqs: WAY-AQR, WAY-SMA
BIOE 103: Systems Physiology and Design
Physiology of intact human tissues, organs, and organ systems in health and disease, and bioengineering tools used (or needed) to probe and model these physiological systems. Topics: Clinical physiology, network physiology and system design/plasticity, diseases and interventions (major syndromes, simulation, and treatment, instrumentation for intervention, stimulation, diagnosis, and prevention), and new technologies including tissue engineering and optogenetics. Discussions of pathology of these systems in a clinical-case based format, with a view towards identifying unmet clinical needs. Learning computational skills that not only enable simulation of these systems but also apply more broadly to biomedical data analysis. Prerequisites:
CME 102;
PHYSICS 41;
BIO 82 OR 83;
BIO 84.
CS 106A or programming experience highly recommended.
Terms: Spr
| Units: 4
| UG Reqs: WAY-SMA, WAY-AQR
Instructors:
Deisseroth, K. (PI)
;
Engel, A. (PI)
;
Fischbach, M. (PI)
...
more instructors for BIOE 103 »
Instructors:
Deisseroth, K. (PI)
;
Engel, A. (PI)
;
Fischbach, M. (PI)
;
Kehnemouyi, Y. (TA)
;
Kim, N. (TA)
;
Maddineni, S. (TA)
;
Pai S, A. (TA)
BIOE 103B: Systems Physiology and Design
ONLINE Offering of
BIOE 103. This pilot class,
BIOE103B, is an entirely online offering with the same content, learning goals, and prerequisites as
BIOE 103. The class is open to BioE-declared students who are not on campus in the spring. Students attend class by watching videos and completing assignments remotely. Physiology of intact human tissues, organs, and organ systems in health and disease, and bioengineering tools used (or needed) to probe and model these physiological systems. Topics: Clinical physiology, network physiology and system design/plasticity, diseases and interventions (major syndromes, simulation, and treatment, instrumentation for intervention, stimulation, diagnosis, and prevention), and new technologies including tissue engineering and optogenetics. Discussions of pathology of these systems in a clinical case-based format, with a view towards identifying unmet clinical needs. Learning computational skills that not only enable simulation of these systems but also apply more broadly to biomedical data analysis. Prerequisites:
CME 102;
PHYSICS 41;
BIO 82 OR 83;
BIO 84.
CS 106A or programming experience highly recommended.
Last offered: Spring 2023
| UG Reqs: WAY-AQR, WAY-SMA
BIOE 122: BioSecurity and Pandemic Resilience (EMED 122, EMED 222, PUBLPOL 122, PUBLPOL 222)
Overview of the most pressing biosecurity issues facing the world today, with a special focus on the COVID-19 pandemic. Critical examination of ways of enhancing biosecurity and pandemic resilience to the current and future pandemics. Examination of how the US and the world are able to withstand a pandemic or a bioterrorism attack, how the medical/healthcare field, government, and technology sectors are involved in biosecurity and pandemic or bioterrorism preparedness and response and how they interface; the rise of synthetic biology with its promises and threats; global bio-surveillance; effectiveness of various containment and mitigation measures; hospital surge capacity; medical challenges; development, production, and distribution of countermeasures such as vaccines and drugs; supply chain challenges; public health and policy aspects of pandemic preparedness and response; administrative and engineering controls to enhance pandemic resilience; testing approaches and challenges; prom
more »
Overview of the most pressing biosecurity issues facing the world today, with a special focus on the COVID-19 pandemic. Critical examination of ways of enhancing biosecurity and pandemic resilience to the current and future pandemics. Examination of how the US and the world are able to withstand a pandemic or a bioterrorism attack, how the medical/healthcare field, government, and technology sectors are involved in biosecurity and pandemic or bioterrorism preparedness and response and how they interface; the rise of synthetic biology with its promises and threats; global bio-surveillance; effectiveness of various containment and mitigation measures; hospital surge capacity; medical challenges; development, production, and distribution of countermeasures such as vaccines and drugs; supply chain challenges; public health and policy aspects of pandemic preparedness and response; administrative and engineering controls to enhance pandemic resilience; testing approaches and challenges; promising technologies for pandemic response and resilience, and other relevant topics. Guest lecturers have included former Secretary of State Condoleezza Rice, former Special Assistant on BioSecurity to Presidents Clinton and Bush Jr. Dr. Ken Bernard, former Assistant Secretary of Health and Human Services Dr. Robert Kadlec, eminent scientists, public health leaders, innovators and physicians in the field, and leaders of relevant technology companies. Open to medical, graduate, and undergraduate students. No prior background in biology necessary. Must be taken for at least 4 units to get WAYs credit. Students also have an option to take the class for 2 units as a speaker series/seminar where they attend half the class sessions (or more) and complete short weekly assignments. In -person, asynchronous synchronous online instruction are available.
Terms: Win
| Units: 2-5
| UG Reqs: GER: DB-NatSci, GER:EC-GlobalCom, WAY-SI
| Repeatable
3 times
(up to 15 units total)
Instructors:
Trounce, M. (PI)
BIOE 123: Bioengineering Systems Prototyping Lab
The Bioengineering System Prototyping Laboratory is a fast-paced, team-based system engineering experience, in which teams of 2-3 students design and build a bioengineering-relevant system (e.g., centrifuge) that meets a set of common requirements along with a set of unique team-determined requirements. Students learn-by-doing hands-on skills in electronics and mechanical design and fabrication. Teams also develop process skills and an engineering mindset by aligning specifications with requirements, developing output metrics and measuring performance, and creating project proposals and plans. The course culminates in demonstration of a fully functioning system that meets the teams' self-determined metrics. Learning goals: 1) Design, fabricate, integrate, and characterize practical electronic and mechanical hardware systems that meet clear requirements in the context of Bioengineering (i.e., build something that works). 2) Use prototyping tools, techniques, and instruments, including:
more »
The Bioengineering System Prototyping Laboratory is a fast-paced, team-based system engineering experience, in which teams of 2-3 students design and build a bioengineering-relevant system (e.g., centrifuge) that meets a set of common requirements along with a set of unique team-determined requirements. Students learn-by-doing hands-on skills in electronics and mechanical design and fabrication. Teams also develop process skills and an engineering mindset by aligning specifications with requirements, developing output metrics and measuring performance, and creating project proposals and plans. The course culminates in demonstration of a fully functioning system that meets the teams' self-determined metrics. Learning goals: 1) Design, fabricate, integrate, and characterize practical electronic and mechanical hardware systems that meet clear requirements in the context of Bioengineering (i.e., build something that works). 2) Use prototyping tools, techniques, and instruments, including: CAD, 3D printing, laser cutting, microcontrollers, and oscilloscopes. 3) Create quantitative system specifications and test measurement plans to demonstrate that a design meets user requirements. 4) Communicate design elements, choices, specifications, and performance through design reviews and written reports. 5) Collaborate as a team member on a complex system design project (e.g., a centrifuge). Limited enrollment, with priority for Bioengineering undergraduates. Prerequisites:
Physics 43, or equivalent. Experience with Matlab and/or Python is recommended.
Terms: Win
| Units: 4
| UG Reqs: WAY-SMA
Instructors:
Boahen, K. (PI)
;
Venook, R. (PI)
;
Bradfield, A. (TA)
...
more instructors for BIOE 123 »
Instructors:
Boahen, K. (PI)
;
Venook, R. (PI)
;
Bradfield, A. (TA)
;
Cheng, J. (TA)
;
Espinoza Campomanes, L. (TA)
;
Fujita, H. (TA)
;
Leffell, A. (TA)
;
Niu, W. (TA)
BIOE 131: Ethics in Bioengineering (ETHICSOC 131X)
Bioengineering focuses on the development and application of new technologies in the biology and medicine. These technologies often have powerful effects on living systems at the microscopic and macroscopic level. They can provide great benefit to society, but they also can be used in dangerous or damaging ways. These effects may be positive or negative, and so it is critical that bioengineers understand the basic principles of ethics when thinking about how the technologies they develop can and should be applied. On a personal level, every bioengineer should understand the basic principles of ethical behavior in the professional setting. This course will involve substantial writing, and will use case-study methodology to introduce both societal and personal ethical principles, with a focus on practical applications
Terms: Spr
| Units: 3
| UG Reqs: GER:EC-EthicReas, WAY-ER
Instructors:
Altman, R. (PI)
;
Magnus, D. (PI)
;
Cooper, E. (TA)
...
more instructors for BIOE 131 »
Instructors:
Altman, R. (PI)
;
Magnus, D. (PI)
;
Cooper, E. (TA)
;
Kim, Y. (TA)
;
McRae, K. (TA)
;
Soh, J. (TA)
;
Wang, X. (TA)
;
Wang, Y. (TA)
;
Wilson, S. (TA)
BIOE 141A: Senior Capstone Design I
First course of two-quarter sequence. Team-based project introduces students to the process of designing new bioengineering technologies to address unmet societal needs. Methods and processes include need specification, brainstorming, concept selection, system specification, and system engineering/design via iterative prototyping and experimentation. First quarter focuses on the innovation process, with teams going from need-specification to initial project plans. Lectures and labs include interactive project work and expert speakers. Prerequisites: BIOE123 and
BIOE44.
Terms: Aut
| Units: 4
BIOE 141B: Senior Capstone Design II
Second course of two-quarter sequence. Team based project introduces students to the process of designing new bioengineering technologies to address unmet societal needs. Focus is on implementation and demonstration of technical feasibility of the first quarter design. Primary deliverables/timelines based on each team's project plan, with weekly mentoring and design reviews during lecture/lab. Guest sessions introduce next-step aspects of bioengineering innovation projects: regulation, intellectual property, commercialization. Prerequisites: BIOE123 and
BIOE44. Limited to seniors in Bioengineering (or instructor consent).
Terms: Win
| Units: 4
BIOE 150: Biochemical Engineering (CHEMENG 150, CHEMENG 250)
Combines biological knowledge and methods with quantitative engineering principles. Quantitative review of biochemistry and metabolism as well as recombinant DNA technology and synthetic biology (metabolic engineering). The course begins with a review of basic cell biology, proceeds to bioprocess design and development, and ends with applied synthetic biology methods and examples. Prerequisite:
CHEMENG 181 or equivalent.
Terms: Win
| Units: 3
Instructors:
Swartz, J. (PI)
;
Voulgaropoulos, A. (TA)
BIOE 158: Soft Matter in Biomedical Devices, Microelectronics, and Everyday Life (MATSCI 158)
The relationships between molecular structure, morphology, and the unique physical, chemical, and mechanical behavior of polymers and other types of soft matter are discussed. Topics include methods for preparing synthetic polymers and examination of how enthalpy and entropy determine conformation, solubility, mechanical behavior, microphase separation, crystallinity, glass transitions, elasticity, and linear viscoelasticity. Case studies covering polymers in biomedical devices and microelectronics will be covered. Recommended:
ENGR 50 and
Chem 31A or equivalent.
Last offered: Winter 2020
| UG Reqs: WAY-AQR, WAY-SMA
Filter Results: