printer friendly pageME 280: Skeletal Development and Evolution (BIOE 280)
The mechanobiology of skeletal growth, adaptation, regeneration, and aging is considered from developmental and evolutionary perspectives. Emphasis is on the interactions between mechanical and chemical factors in the regulation of connective tissue biology. Prerequisites:
BIO 42, and
ME 80 or
BIOE 42.
Last offered: Spring 2010
ME 287: Mechanics of Biological Tissues
Introduction to the mechanical behaviors of biological tissues in health and disease. Overview of experimental approaches to evaluating tissue properties and mathematical constitutive models. Elastic behaviors of hard tissues, nonlinear elastic and viscoelastic models for soft tissues.
Terms: Win
| Units: 4
ME 337: Mechanics of Growth
Introduction to continuum theory and computational simulation of living matter. Kinematics of finite growth. Balance equations in open system thermodynamics. Constitutive equations for living systems. Custom-designed finite element solution strategies. Analytical solutions for simple model problems. Numerical solutions for clinically relevant problems such as: bone remodeling; wound healing; tumor growth; atherosclerosis; heart failure; tissue expansion; and high performance training.
Last offered: Winter 2015
ME 385: Tissue Engineering Lab
Hands-on experience in the fabrication of living engineered tissues. Techniques include sterile technique, culture of mammalian cells, creation of cell-seeded scaffolds, and the effects of mechanical loading on the metabolism of living engineered tissues. Theory, background, and practical demonstration for each technique. Lab.
Last offered: Winter 2008
ME 387: Soft Tissue Mechanics
Structure/function relationships and mechanical properties of soft tissues, including nonlinear elasticity, viscoelasticity, and poroelasticity.
Last offered: Winter 2011
ME 388: Transport Modeling for Biological Systems
Introduction to electric fields, fluid flows, transport phenomena and their application to biological systems. Maxwell's equations, electrostatics, electro-chemical-mechanical driving forces in physiological systems. Ionic diffusion in electrolytes and membrane transport. Fluid and solid continua theory for porous, hydrated biological tissues. Applications include ionic and molecular transport in tissues and cells, electrophoresis, electromechanical and physicochemical interactions in cells and the extracellular matrix of connective tissue.
ORTHO 260: Tissue Engineering (BIOE 260)
Principles of tissue engineering and design strategies for practical applications for tissue repair. Topics include tissue morphogenesis, stem cells, biomaterials, controlled drug and gene delivery, and paper discussions. Students will learn skills for lab research through interactive lectures, paper discussions and research proposal development. Students work in small teams to work on develop research proposal for authentic tissue engineering problems. Lab sessions will teach techniques for culturing cells in 3D, as well as fabricating and characterizing hydrogels as 3D cell niche.
Terms: Spr
| Units: 4
ORTHO 270: Orthopaedic Tissue Engineering
Biological principles underlying the use of engineering strategies and biocompatible materials for tissue repair and regeneration. Structure, physiology, and mechanics of articular cartilage, bone, and dense soft connective tissues. Current ideas, approaches, and applications being implemented as therapeutic regimens for arthritis, spinal deformities, and limb salvage. Multidisciplinary constraints on the design and creation of tissue constructs. Students enrolling for 2 units prepare a presentation and final project. Prerequisite: familiarity with basic cell and molecular mechanisms underlying tissue differentiation.
Terms: Win
| Units: 1-2
SIS 135Q: Stanford Introductory Seminar: Tissue Engineering: Ethics, Genes and Cells
SURG 68Q: Current Concepts in Transplantation
Preference to sophomores. Biological aspects of cell and organ transplantation, including issues that arise in the popular media. Diseases for which transplantation is a treatment, the state of the art in human transplantation, transplantation of animal tissue into humans (xenotransplantation), development of new tissue and organs in the laboratory (tissue engineering and cloning), and development of drugs and biological strategies to promote long-term survival of the tissue or organ (tolerance). How to write a scientific abstract, critique scientific literature, and research and present topics in contemporary transplantation.
Last offered: Spring 2016
| UG Reqs: Writing 2
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