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BIOS 215: Transplantation Immunology and Tolerance

Extensive literature review of experimental strategies to promote tolerance, including limitations involved in translating tolerance-promoting strategies to the clinic and targets of Immunosuppression. State of art approaches and limitations of current approaches. Discussions with prominent scientists and clinicians in field of transplantation. Student presentations on novel concepts and approaches in basic science, translational and clinical transplant.
Terms: not given this year | Units: 2 | Grading: Medical Option (Med-Ltr-CR/NC)

CHPR 260: Prevention Across Medical Disciplines: Evidence-based Guidelines

Coordinated seminar series presenting evidence-based health promotion and disease prevention guidelines by research and clinical faculty of multiple divisions of Stanford's Department of Medicine, including cardiovascular medicine, oncology, nephrology, immunology and rheumatology, infectious diseases, endocrinology, gerontology and metabolism, gastroenterology and hepatology, hematology, blood and marrow transplantation, pulmonary and critical care medicine, general medical disciplines (including family medicine). Key prevention issues addressed in primary care and outcomes research, biomedical informatics research and the Stanford Prevention Research Center also presented. Enrollment priority given to CHPR Master's students. CHPR students must enroll for letter grade.Prerequisite: CHPR 201 or HUMBIO 126/CHPR 226 or equivalent or consent of instructor.
Terms: Win | Units: 3 | Grading: Medical Option (Med-Ltr-CR/NC)
Instructors: ; Stefanick, M. (PI)

DBIO 201: Cells and Signaling in Regenerative Medicine

Conserved molecular and cellular pathways regulate tissue and organ homeostasis. Errors in these pathways result in human diseases.nManipulation of key cells and signals is leading to new strategies for stimulating tissue formation and regeneration.nTopics: Stem cells. Molecules regulating stem cell proliferation and differentiation. Signaling pathways. Gene regulation. Embryonic stemncells. Programmed cell death. Cell lineage. Tissue regeneration. Use of stem cells in transplantation. Organoids. Emphasis on links between stem cells, signals, and clinically significant topics including diabetes, bone loss, cancer, and aging.
Terms: Win | Units: 2 | Grading: Medical Option (Med-Ltr-CR/NC)
Instructors: ; Nusse, R. (PI)

ECON 182: Honors Market Design

Rigorous introduction to the theory of matching and resource allocation, and its application to practical market design. Theory covers two-sided matching, "house allocation" problems, random assignment, and their variants. Applied topics include school choice, labor market, house allocation, and organ allocation for transplantation. Final paper required. Forms a sequence with ECON 180 and ECON 181, but can be taken independently. Prerequisites: Experience with abstract mathematics and willingness tonwork hard. No prior knowledge of economics is required, although basic knowledge in game theory is useful.
Terms: Spr | Units: 5 | UG Reqs: WAY-FR | Grading: Letter or Credit/No Credit
Instructors: ; Kojima, F. (PI)

ECON 285: Matching and Market Design

This is an introduction to market design, intended mainly for second year PhD students in economics (but also open to other graduates students from around the university and to undergrads who have taken undergrad market design). It will emphasize the combined use of economic theory, experiments and empirical analysis to analyze and engineer market rules and institutions. In this first quarter we will pay particular attention to matching markets, which are those in which price doesn't do all of the work, and which include some kind of application or selection process. In recent years market designers have participated in the design and implementation of a number of marketplaces, and the course will emphasize the relation between theory and practice, for example in the design of labor market clearinghouses for American doctors, and school choice programs in a growing number of American cities (including New York and Boston), and the allocation of organs for transplantation. Various forms of market failure will also be discussed.nAssignment: One final paper. The objective of the final paper is to study an existing market or an environment with a potential role for a market, describe the relevant market design questions, and evaluate how the current market design works and/or propose improvements on the current design.
Terms: Aut | Units: 2-5 | Grading: Letter or Credit/No Credit

IMMUNOL 205: Immunology in Health and Disease

Concepts and application of adaptive and innate immunology and the role of the immune system in human diseases. Case presentations of diseases including autoimmune diseases, infectious disease and vaccination, hematopoietic and solid organ transplantation, cancer immunotherapy, genetic and acquired immunodeficiencies, hypersensitivity reactions, and allergic diseases. Problem sets based on lectures and current clinical literature. Laboratory in acute and chronic inflammation.
Terms: Win | Units: 4 | Grading: Medical Option (Med-Ltr-CR/NC)

IMMUNOL 209: Translational Immunology

(Open to medical students in the Immunology concentration, graduate students, undergraduates by consent of instructor) Journal style format focusing on current basic immunology research and how it is translated into immunotherapies and clinical trials. Topics include hematopoiesis, transplantation, tolerance, immune monitoring, vaccination, autoimmunity and antibodies, rheumatoid arthritis, chronic pulmonary disease, and asthma. May be repeated for credit.
Terms: Win, Spr | Units: 1 | Repeatable for credit | Grading: Medical Option (Med-Ltr-CR/NC)
Instructors: ; Bollyky, P. (PI)

IMMUNOL 315: Special Topics in Immunology

Directed readings and survey study of these topics in human and mousenimmunology: cells of the immune system; innate and adaptive immunity; antibodies and antigens; histocompatibility complex; lymphocyte development and the rearrangement and expression of antigen receptor genes; T-cell and B-cell signaling and activation; immunological tolerance; transplantation; diseases caused by immune responses; allergy; congenital and acquired immunodeficiencies. Graduate students outside immunology and Postdoctoral fellows and clinical fellows are welcome.
Terms: not given this year | Units: 1 | Repeatable for credit | Grading: Medical Option (Med-Ltr-CR/NC)

LAW 5016: Japanese Law, Society and Economy

This course provides a critical introduction to the institutions and actors that comprise the Japanese legal system. Throughout the course, law is examined within the broader context of Japanese social, political, and economic institutions. Topics covered include the legal profession, constitutional law, dispute resolution, family law, employment law, and corporate law. Leading scholarly commentaries on law's role in Japanese life are also examined and critiqued. Thematically, the course offers an extended exploration of the "transplantation" of foreign law and the role of law in Japan's social structure and economic development. All readings and instruction are in English. Japanese language ability and knowledge of Japan are not required. Elements used in grading: Attendance, Class Participation, Written Assignment, and Final Exam.
Terms: Win | Units: 3 | Grading: Law Honors/Pass/Restrd Cr/Fail
Instructors: ; Milhaupt, C. (PI)

PATH 290: Pediatric Nonmalignant Hematology and Stem Cell Biology

Pediatric hematologic disorders provide an important paradigm to study other developmental systems. Subjects covered include hematopoiesis, basic stem cell biology, endothelial cell development, alternative models to study nonmalignant hematology and stem cell biology (zebrafish and drosophila), defects in white cell function, basic research in stem cell transplantation, state of the art methods in nonmalignant hematology and stem cell biology (genomics, proteomics, and gene therapy), and bioinformatics. The course is also open to graduate students and junior and senior undergraduate students who are pre-med.
Terms: Aut | Units: 2 | Grading: Medical Option (Med-Ltr-CR/NC)
Instructors: ; Sakamoto, K. (PI)

PEDS 251A: Medical Ethics I

Required for Scholarly Concentration in Biomedical Ethics and Medical Humanities. The field of bioethics, including theoretical approaches to bioethical problems. Contemporary controversies and clinical cases. Values that arise in different situations and clinical encounters. Issues include: genetics and stem cell research, rationing, ethical issues in care at the end of life, organ transplantation issues.
Terms: Win | Units: 2 | Grading: Medical Option (Med-Ltr-CR/NC)

SIS 283Q: Stanford Introductory Seminar: Current Concepts in Transplantation

Units: 3 | Grading: Letter (ABCD/NP)

SIS 376Q: Stanford Introductory Seminar: Current Concepts in Transplantation

Units: 3 | Grading: Letter or Credit/No Credit

SOMGEN 214: Conversations in Social Medicine

Draws on disciplines of medical anthropology, medical sociology, medical humanities, philosophy, and ethics to explore the field of social medicine. Focus is on consideration of medicine as both a biological and social event: how assumptions we have about the body and disease are socially constructed, how medicine exists in rituals and structures, and how considering medicine from this perspective can help us be better doctors. Topics include: organ transplantation, knowledge production, mental illness, and language in medicine.
Terms: not given this year | Units: 1 | Repeatable for credit | Grading: Medical Satisfactory/No Credit

STEMREM 201A: Stem Cells and Human Development: From Embryo to Cell Lineage Determination

For graduate, medical, and advanced undergraduate students. Prepares students for the future of regenerative medicine by exploring central concepts in stem cell biology and the actual experiments that led to these concepts. Provides educational foundation for future physician-scientists to understand mechanisms underlying regenerative therapies. The latest advances in stem cell research will be discussed, including tissue regeneration; how stem cells are discovered by lineage tracing or transplantation; how stem cells differentiate and form organized tissues; stem cell niches; signaling centers and extracellular signals; chromatin and cellular reprogramming; organoids; and cancer stem cells, with emphasis on unresolved issues in the field.
Terms: Aut | Units: 1-3 | Grading: Medical Option (Med-Ltr-CR/NC)

SURG 68Q: Current Concepts in Transplantation

Preference to sophomores. Biological aspects of cell and organ transplantation, including issues that arise in the popular media. Diseases for which transplantation is a treatment, the state of the art in human transplantation, transplantation of animal tissue into humans (xenotransplantation), development of new tissue and organs in the laboratory (tissue engineering and cloning), and development of drugs and biological strategies to promote long-term survival of the tissue or organ (tolerance). How to write a scientific abstract, critique scientific literature, and research and present topics in contemporary transplantation.
Terms: Spr | Units: 3 | UG Reqs: Writing 2 | Grading: Letter or Credit/No Credit

SURG 70Q: Surgical Anatomy of the Hand: From Rodin to Reconstruction

The surgical anatomy of the hand is extremely complex in terms of structure and function. Exploration of the anatomy of the hand in different contexts: its representation in art forms, the historical development of the study of hand anatomy, current operative techniques for reconstruction, advances in tissue engineering, and the future of hand transplantation.
Terms: Win | Units: 2 | Grading: Letter or Credit/No Credit
Instructors: ; Chang, J. (PI)

SURG 204: Introduction to Surgery

This lunch seminar is designed to give preclinical medical students a broad overview of surgical specialties and life as a surgeon. Interactive talks by leading surgeons from the General Surgery, Plastic Surgery, Neurosurgery, Orthopedic Surgery, Head and Neck Surgery, Transplantation Surgery, and Cardiac Surgery departments will highlight the array of operation types performed and diseases and conditions encountered in their disciplines. In addition, each lecturer will provide students with a ¿road map¿ as to how to successfully enter each specialty field of surgery. Lunch will be provided.
Terms: Aut | Units: 1 | Grading: Medical School MD Grades
Instructors: ; Lau, J. (PI)
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