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NSUR 81N: Mitochondrial Transport and Function in Neuronal Health and Death

As our population continues to age, age-dependent neurodegenerative diseases such as Parkinson's, Alzheimer's, and ALS are becoming more prevalent and thus pose a daunting danger to public health nationwide. Effective treatments are desperately needed, however, we still know very little about how neurons die in those diseases. One organelle that is especially important to neuronal health is mitochondria, the power plants for the cell. In this IntroSem, we will learn how neurons employ molecular machinery to regulate, transport, and distribute mitochondria, and importantly, how these fundamental regulations are compromised in neurological disorders. A hands-on laboratory section is available for students who are interested in learning imaging mitochondrial transport in live cells using confocal microscopy. The laboratory section is located at the beautiful Arastradero campus, which provides a unique opportunities for first-year students to explore Stanford campuses and adjacent areas.Prerequisites: High school biology.
Terms: Aut | Units: 3
Instructors: ; Wang, X. (PI)
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