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MI 115B: The Vaccine Revolution

Advanced seminar. Human aspects of viral disease, focusing on recent discoveries in vaccine development and emerging infections. Journal club format: students choose articles from primary scientific literature, write formal summaries, and synthesize them into a literature review. Emphasis is on analysis, experimental design, and interpretation of data. Oral presentations. Enrollment limited to 8. Prerequisite: prior enrollment in MI 116, The Human Virosphere or consent of instructor required.
Terms: Spr | Units: 6 | Grading: Letter (ABCD/NP)
Instructors: ; Siegel, R. (PI)

MI 198: Directed Reading in Microbiology and Immunology

Fields of study are decided in consultation with sponsoring professor. Prerequisite: consent of instructor.
Terms: Aut, Win, Spr, Sum | Units: 1-15 | Repeatable for credit | Grading: Letter or Credit/No Credit

MI 199: Undergraduate Research

Investigations sponsored by individual faculty members. Possible fields: microbial molecular biology and physiology, microbial pathogenicity, immunology, virology, and molecular parasitology. Prerequisite: consent of instructor.
Terms: Aut, Win, Spr, Sum | Units: 1-18 | Repeatable for credit | Grading: Letter or Credit/No Credit

MI 215: Principles of Biological Technologies

The principles underlying novel as well as commonly utilized techniques to answer biological questions. Lectures and primary literature critiques on topics such as fluorescence microscopy, including applications such as FRET and single-cell analysis; human and murine genetic analysis; FACS; proteomics and analysis of noncoding RNAs. Class participation is emphasized. Prerequisite: biochemistry. Required of first-year graduate students in Microbiology and Immunology and the Immunology program.
Terms: Spr | Units: 3 | Grading: Medical Option (Med-Ltr-CR/NC)
Instructors: ; Sarnow, P. (PI)

MI 217: Genome Editing: Redefining Humanity

Genome Editing is potentially the most important biological/medical strategy ever developed. Genome Editing has been used to manipulate diverse organisms and viruses including bacteria, plants, insects, nonhuman animals, human remediation, and treatment of genetic and other diseases in animals and humans. The advent of CRISPR-Cas9 and newer techniques has greatly increased the facility and speed with which Genome Editing can be carried out. It has become clear that the main factors limiting the power of Genome Editing are the human imagination and human imposed structures, - not technological limitations.
Terms: Spr | Units: 4 | Grading: Letter or Credit/No Credit
Instructors: ; Siegel, R. (PI)

MI 221: Gut Microbiota in Health and Disease (BIOE 221G, GENE 208)

Preference to graduate students. Focus is on the human gut microbiota. Students enrolling for 3 units receive instruction on computational approaches to analyze microbiome data and must complete a related project.
Terms: Spr | Units: 2-3 | Grading: Medical Option (Med-Ltr-CR/NC)

MI 250: Frontiers in Microbiology and Immunology

Required of first- and second-year students in Microbiology and Immunology. How to evaluate biological research. Held in conjunction with the Microbiology and Immunology Friday noon seminar series. Before the seminar, students and faculty discuss one or more papers from the speaker's primary research literature on a related topic. After the seminar, students meet informally with the speaker to discuss their research.
Terms: Aut, Win, Spr | Units: 1 | Repeatable for credit | Grading: Medical Option (Med-Ltr-CR/NC)
Instructors: ; Sonnenburg, J. (PI)

MI 370: Medical Scholars Research

Provides an opportunity for student and faculty interaction, as well as academic credit and financial support, to medical students who undertake original research. Enrollment is limited to students with approved projects.
Terms: Aut, Win, Spr, Sum | Units: 4-18 | Repeatable for credit | Grading: Medical School MD Grades

MI 399: Graduate Research

Students who have completed the necessary foundation courses undertake investigations in general bacteriology, bacterial physiology and ecology, bacterial genetics, microbial pathogenicity, immunology, parasitology, or virology sponsored by individual faculty members. Prerequisite: consent of instructor.
Terms: Aut, Win, Spr, Sum | Units: 1-18 | Repeatable for credit | Grading: Medical Satisfactory/No Credit
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