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## BIOS 262:Learning to Fly: Drosophila Research Methods

This week-long mini-course will be an overview of the fly as a model system, and the tools available to fly researchers. It will cover topics like history, anatomy, development, online databases, genetic toolkits, genome editing techniques, and stem cell, immunology, and neural research methods. Lectures will be given by experts in the field, who will also be encouraged to discuss the advantages and disadvantages of the fly, as well as how this model system differs from vertebrate systems. We will also provide an optional 2-hour lab that will expose students who have little fly experience to basic fly techniques.
Terms: not given this year | Units: 1 | Grading: Medical Option (Med-Ltr-CR/NC)

## CHPR 290:Advanced Statistical Methods for Observational Studies (EDUC 260B, HRP 292, STATS 266)

Design principles and statistical methods for observational studies. Topics include: matching methods, sensitivity analysis, and instrumental variables. 3 unit registration requires a small project and presentation. Computing is in R. Pre-requisites: HRP 261 and 262 or STAT 209 ( HRP 239), or equivalent. See http://rogosateaching.com/somgen290/
Terms: Spr | Units: 2-3 | Grading: Medical Option (Med-Ltr-CR/NC)

## HRP 262:Intermediate Biostatistics: Regression, Prediction, Survival Analysis (STATS 262)

Methods for analyzing longitudinal data. Topics include Kaplan-Meier methods, Cox regression, hazard ratios, time-dependent variables, longitudinal data structures, profile plots, missing data, modeling change, MANOVA, repeated-measures ANOVA, GEE, and mixed models. Emphasis is on practical applications. Prerequisites: basic ANOVA and linear regression.
Terms: Spr | Units: 3 | Grading: Medical Option (Med-Ltr-CR/NC)
Instructors: ; Sainani, K. (PI)

## HRP 292:Advanced Statistical Methods for Observational Studies (CHPR 290, EDUC 260B, STATS 266)

Design principles and statistical methods for observational studies. Topics include: matching methods, sensitivity analysis, and instrumental variables. 3 unit registration requires a small project and presentation. Computing is in R. Pre-requisites: HRP 261 and 262 or STAT 209 ( HRP 239), or equivalent. See http://rogosateaching.com/somgen290/
Terms: Spr | Units: 2-3 | Grading: Medical Option (Med-Ltr-CR/NC)

## MED 262:Economics of Health Improvement in Developing Countries (ECON 127)

Application of economic paradigms and empirical methods to health improvement in developing countries. Emphasis is on unifying analytic frameworks and evaluation of empirical evidence. How economic views differ from public health, medicine, and epidemiology; analytic paradigms for health and population change; the demand for health; the role of health in international development. Prerequisites: ECON 50 and ECON 102B.
Terms: Spr | Units: 5 | Grading: Medical Option (Med-Ltr-CR/NC)
Instructors: ; Miller, G. (PI)

## NSUR 262:2 Photon Imaging of Neural Circuits

Advances in 2-photon microscopy have allowed unprecedented leaps in understanding the structure and function of neural circuits. This hands-on laboratory based course offers a deep dive about 2-photon microscopy for neuroscience. This course will be structures in such a way that students learn fundamental principles about optics, neuronal morphology, and calcium signaling directly from the experiments we perform in the laboratory and discussions during lectures.
Terms: not given this year | Units: 3-4 | Grading: Medical Option (Med-Ltr-CR/NC)