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GENE 235: C. Elegans Genetics

Genetic approaches to C. elegans, practice in designing experiments and demonstrations of its growth and anatomy. Probable topics include: growth and genetics, genome map and sequence, mutant screens that start with a desired phenotype, reverse genetics and RNAi screens, genetic duplications, uses of null phenotype non-null alleles, genetic interactions and pathway analysis, and embryogenesis and cell lineage. Focus of action, mosaic analysis, and interface with embryological and evolutionary approaches.
Terms: Spr, alternate years, not given next year | Units: 2 | Grading: Medical Option (Med-Ltr-CR/NC)
Instructors: ; Fire, A. (PI)
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