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GENE 19SI: Impact Investing in Neuroscience

The course will feature seminar-style lectures to examine various scenarios of investing for impact, incorporating both social and financial return metrics. Primary focus will be on developing ideas on best practices that will guide efficient allocation of funding in research, and early and later stage ventures for the advancement of the neuroscience sector and its impact on patients worldwide. Students will be able to engage with invited guest speakers, professionals within academia, non-profit and for-profit sectors, and learn about current practices in impact investing.
Terms: Win | Units: 2 | Grading: Satisfactory/No Credit

GENE 104Q: Law and the Biosciences

Preference to sophomores. Focus is on human genetics; also assisted reproduction and neuroscience. Topics include forensic use of DNA, genetic testing, genetic discrimination, eugenics, cloning, pre-implantation genetic diagnosis, neuroscientific methods of lie detection, and genetic or neuroscience enhancement. Student presentations on research paper conclusions.
Terms: Win | Units: 3 | UG Reqs: WAY-ER, Writing 2 | Grading: Letter or Credit/No Credit
Instructors: ; Greely, H. (PI)

GENE 205: Advanced Genetics

For PhD students in any of the Biosciences Departments and Programs at Stanford University. Emphasis on developing the ability to solve problems using genetic ideas and methods, to understand the nature and reliability of genetic inference, and to apply genetic reasoning to biological research. Weekly paper discussions based on original research papers that define or illustrate the ideas and techniques covered in the lecture.
Terms: Win | Units: 3 | Grading: Medical Option (Med-Ltr-CR/NC)

GENE 207: Microfluidic Device Laboratory (BIOE 301D)

This course exposes students to the design, fabrication, and testing of microfluidic devices for biological applications through combination of lectures and hands-on lab sessions. In teams of two, students will produce a working prototype devices designed to address specific design challenges within the biological community using photolithography, soft lithography, and imaging techniques.
Terms: Win | Units: 3-4 | Grading: Letter or Credit/No Credit

GENE 211: Genomics

The goal of this course is to explore different genomic approaches and technologies, to learn how they work from a molecular biology view point, and to understand how they can be applied to understanding biological systems. In addition, we teach material on how the data generated from these approaches can be analyzed, from an algorithmic perspective. The papers that are discussed are a mixture of algorithmic papers, and technological papers. Finally, the course has a strong programming component, with Python being the language that we teach. All of our problem sets require Python programming - while beginning programmers succeed in our course, it is a steep learning curve, and the problem sets can require a significant time investment.
Terms: Win | Units: 3 | Grading: Medical Option (Med-Ltr-CR/NC)

GENE 215: Frontiers in Biological Research (BIOC 215, DBIO 215)

Students analyze cutting edge science, develop a logical framework for evaluating evidence and models, and enhance their ability to design original research through exposure to experimental tools and strategies. The class runs in parallel with the Frontiers in Biological Research seminar series. Students and faculty meet on the Tuesday preceding each seminar to discuss a landmark paper in the speaker's field of research. Following the Wednesday seminar, students meet briefly with the speaker for a free-range discussion which can include insights into the speakers' paths into science and how they pick scientific problems.
Terms: Aut, Win, Spr | Units: 1 | Repeatable for credit | Grading: Medical Satisfactory/No Credit

GENE 217: Translational Bioinformatics (BIOE 217, BIOMEDIN 217, CS 275)

Computational methods for the translation of biomedical data into diagnostic, prognostic, and therapeutic applications in medicine. Topics: multi-scale omics data generation and analysis, utility and limitations of public biomedical resources, machine learning and data mining, issues and opportunities in drug discovery, and mobile/digital health solutions. Case studies and course project. Prerequisites: programming ability at the level of CS 106A and familiarity with biology and statistics.
Terms: Win | Units: 4 | Grading: Medical Option (Med-Ltr-CR/NC)

GENE 224: Principles of Pharmacogenomics (BIOMEDIN 224)

This course is an introduction to pharmacogenomics, including the relevant pharmacology, genomics, experimental methods (sequencing, expression, genotyping), data analysis methods and bioinformatics. The course reviews key gene classes (e.g., cytochromes, transporters) and key drugs (e.g., warfarin, clopidogrel, statins, cancer drugs) in the field. Resources for pharmacogenomics (e.g., PharmGKB, Drugbank, NCBI resources) are reviewed, as well as issues implementing pharmacogenomics testing in the clinical setting. Reading of key papers, including student presentations of this work; problem sets; final project selected with approval of instructor. Prerequisites: two of BIO 41, 42, 43, 44X, 44Y or consent of instructor.
Terms: Aut, Win, Spr, Sum | Units: 3 | Grading: Medical Option (Med-Ltr-CR/NC)

GENE 274A: A Case Based Approach to Clinical Genetics (CHPR 274A)

For genetic counseling students, graduate students in genetics, medical students, residents and fellows. Case-based scenarios and guest expert lectures. Students learn skills in case preparation, management, and presentation, as well as content around common genetic disorders.
Terms: Win | Units: 2 | Grading: Medical Option (Med-Ltr-CR/NC)

GENE 276: Genetic Counseling Clinical Rotations

For genetic counseling students only. Supervised clinical experiences. May be repeated for credit. Prerequisite: GENE 275.
Terms: Aut, Win, Spr, Sum | Units: 1-7 | Repeatable for credit | Grading: Medical Option (Med-Ltr-CR/NC)

GENE 278: Prenatal Genetic Counseling (CHPR 278)

Online course for genetic counseling students, graduate students in genetics, medical students, residents, fellows, and nurses interested in prenatal genetics. Genetic counseling students should take this course in conjunction with their initial prenatal genetics rotation. Topics include: prenatal screening and diagnostic testing, ultrasound, genetic carrier screening, teratology, fetal treatment and intervention, perinatal loss, termination, and infertility.
Terms: Aut, Win, Spr, Sum | Units: 1 | Grading: Medical Satisfactory/No Credit
Instructors: ; Campion, M. (PI)

GENE 279: Pediatric and Adult Genetic Counseling (CHPR 279)

Internet based course for genetic counseling students, graduate students in genetics, medical students, residents, and fellows; genetic counseling students should take this course in conjunction with their initial general genetics rotation. Topics include: common genetic conditions, assessment of child development and medical history in the context of a genetic workup, the pediatric genetics medical examination, dysmorphology, introduction to laboratory genetic testing, development of a differential diagnosis, and resources for case management and family support.
Terms: Aut, Win, Spr, Sum | Units: 1 | Grading: Medical Satisfactory/No Credit
Instructors: ; Hanson-Kahn, A. (PI)

GENE 280: Metabolic Genetic Counseling (CHPR 280)

Internet based course for genetic counseling students, graduate students in genetics, medical students, residents, and fellows genetic counseling students should take this course in conjunction with their metabolic genetics rotation. Topics include: overview of metabolic diseases; common pathways; diagnosis, management, and treatment of metabolic disorders; and newborn screening.
Terms: Aut, Win, Spr, Sum | Units: 1 | Grading: Medical Satisfactory/No Credit
Instructors: ; Hanson-Kahn, A. (PI)

GENE 281: Cancer Genetic Counseling (CHPR 281)

Internet based course for genetic counseling students, graduate students in genetics, medical students, residents, and fellows; genetic counseling students should take this course in conjunction with their initial cancer genetics rotation. Topics include: cancer biology and cytogenetics; diagnosis and management of common cancer genetic syndromes¿ predictive testing; psychology of cancer genetic counseling; and topics recommended by ASCO guidelines.
Terms: Aut, Win, Spr, Sum | Units: 1 | Grading: Medical Satisfactory/No Credit
Instructors: ; Ormond, K. (PI)

GENE 282A: Genetic Counseling Research Seminar

For genetic counseling students only. Facilitated discussions on identifying a topic and mentor for genetic counseling departmental research projects.
Terms: Win | Units: 1 | Grading: Medical Option (Med-Ltr-CR/NC)
Instructors: ; Ormond, K. (PI)

GENE 283: Genetic Counseling Research

Genetic counseling students conduct clinical research projects as required by the department for graduation. May be repeated for credit. Pre- or corequisite: GENE 282.
Terms: Aut, Win, Spr, Sum | Units: 1-8 | Repeatable for credit | Grading: Medical Satisfactory/No Credit

GENE 284: Medical Genetics Seminar (CHPR 284)

Presentation of genetics research and cases from the medical genetics and biochemical genetics services. Course may be completed online or in person. Non-GC students: please contact the instructor when you enroll.
Terms: Aut, Win, Spr | Units: 1 | Repeatable for credit | Grading: Medical Option (Med-Ltr-CR/NC)
Instructors: ; Campion, M. (PI)

GENE 285B: Genetics Counseling Seminar

Year-long seminar primarily for genetic counseling students. Winter: The impact of chronic illness and genetic disease across the lifespan.
Terms: Win | Units: 3 | Grading: Medical Option (Med-Ltr-CR/NC)
Instructors: ; Campion, M. (PI)

GENE 286: Advanced Genetic Counseling Seminar

For genetic counseling students only. Psychosocial issues associated with genetic counseling cases are discussed through presentation of cases that students have seen throughout their training. Professional development topics will be included. Must be taken for 3 quarters. Prerequisites: GENE 285 A,B,C and 276.
Terms: Aut, Win, Spr | Units: 2 | Repeatable for credit | Grading: Medical Option (Med-Ltr-CR/NC)

GENE 287: CARDIOVASCULAR GENETICS (CHPR 287)

Online course for genetic counseling students, graduate students in genetics, medical students, residents, fellows, and nurses interested in inherited cardiovascular conditions. Genetic counseling students should take this course in conjunction with their cardiovascular genetics rotation. Topics include: Basic cardiology principles, including relevant anatomy and physiology; diagnosis, management and genetic testing as it relates to common inherited cardiovascular conditions in both the pediatric and adult setting; predictive genetic testing issues specific to inherited cardiovascular conditions; psychological issues related to sudden death conditions.
Terms: Aut, Win, Spr, Sum | Units: 1 | Grading: Medical Satisfactory/No Credit
Instructors: ; Campion, M. (PI)

GENE 288: Neurogenetics

Internet-based course for genetic counseling students, graduate students in genetics, medical students, residents, and fellow; genetic counseling students should take this course in conjunction with their neurogenetics rotation. Topics include: introduction to neurology for beginners, including an overview of neurologic exam and localization, to provide non-neurologist trainees a foundation for understanding the differential diagnosis process in neurology; common and exemplary neurogenetics disorders spanning the adult and pediatric neurologic sub-specialties; key genetic concepts such as triple repeat disorders and FSHD; ethical and psychological topics as well as gene-targets therapeutics. nnMedical students and graduate students outside of genetic counseling should obtain permission from instructor prior to enrollment. No prerequisite for genetic counseling students, genetics or neurology residents/fellows or post-docs.
Terms: Aut, Win, Spr, Sum | Units: 1 | Grading: Medical Satisfactory/No Credit
Instructors: ; Ormond, K. (PI)

GENE 346: Advanced Seminar on Prokaryotic Molecular Biology (BIO 346, CSB 346)

Enrollment limited to PhD students associated with departmental research groups in genetics or molecular biology.
Terms: Aut, Win, Spr | Units: 1 | Grading: Satisfactory/No Credit
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