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IMMUNOL 199: Undergraduate Research

Students undertake investigations sponsored by individual faculty members. Prerequisite: consent of instructor.
Terms: Aut, Win, Spr, Sum | Units: 1-18 | Repeatable for credit
Instructors: ; Alizadeh, A. (PI); Arvin, A. (PI); Bendall, S. (PI); Blish, C. (PI); Bollyky, P. (PI); Boothroyd, J. (PI); Butcher, E. (PI); Butte, A. (PI); Butte, M. (PI); Chen, C. (PI); Chien, Y. (PI); Chu, G. (PI); Cleary, M. (PI); Contag, C. (PI); Crabtree, G. (PI); Davis, M. (PI); Dhabhar, F. (PI); Engleman, E. (PI); Fathman, C. (PI); Felsher, D. (PI); Fontaine, M. (PI); Galli, S. (PI); Garcia, C. (PI); Goronzy, J. (PI); Habtezion, A. (PI); Han, M. (PI); Herzenberg, L. (PI); Hsieh, M. (PI); Idoyaga, J. (PI); Jones, P. (PI); Kim, P. (PI); Krams, S. (PI); Kuo, C. (PI); Lee, P. (PI); Levy, R. (PI); Levy, S. (PI); Lewis, D. (PI); Lewis, R. (PI); Majeti, R. (PI); Martinez, O. (PI); McDevitt, H. (PI); Mellins, E. (PI); Meyer, E. (PI); Michie, S. (PI); Mignot, E. (PI); Miklos, D. (PI); Monack, D. (PI); Nadeau, K. (PI); Negrin, R. (PI); Nicolls, M. (PI); Nolan, G. (PI); Palmer, T. (PI); Parham, P. (PI); Robinson, B. (PI); Sarwal, M. (PI); Schneider, D. (PI); Shafer, R. (PI); Shizuru, J. (PI); Sobel, R. (PI); Steinman, L. (PI); Strober, S. (PI); Sunwoo, J. (PI); Utz, P. (PI); Weissman, I. (PI); Weyand, C. (PI); Winslow, M. (PI); Wu, J. (PI); Wyss-Coray, T. (PI); Jones, D. (GP)

IMMUNOL 201: Advanced Immunology I (MI 211)

For graduate students, medical students and advanced undergraduates. Topics include the innate and adaptive immune systems; genetics, structure, and function of immune molecules; lymphocyte activation and regulation of immune responses. Prerequisites: undergraduate course in Immunology and familiarity with experimental approaches in biochemistry, molecular biology, and cell biology.
Terms: Win | Units: 3
Instructors: ; Chien, Y. (PI)

IMMUNOL 202: Advanced Immunology II (MCP 202)

Readings of immunological literature. Classic problems and emerging areas based on primary literature. Student and faculty presentations. Prerequisite: IMMUNOL 201/MI 211.
Terms: Spr | Units: 3
Instructors: ; Garcia, C. (PI)

IMMUNOL 203: Advanced Immunology III

Key experiments and papers in immunology. Course focuses on the history of Immunology and how current research fits into the historical context. Students work on developing effective presentation skills.
Terms: Sum | Units: 2
Instructors: ; Krams, S. (PI)

IMMUNOL 205: Immunology in Health and Disease

Concepts and application of adaptive and innate immunology and the role of the immune system in human diseases. Case presentations of diseases including autoimmune diseases, infectious disease and vaccination, hematopoietic and solid organ transplantation, genetic and acquired immunodeficiencies, hypersensitivity reactions, and allergic diseases. Problem sets based on lectures and current clinical literature. Laboratory in acute and chronic inflammation.
Terms: Win | Units: 4
Instructors: ; Michie, S. (PI); Beel, A. (TA); Chen, J. (TA); Erickson, A. (TA); Gray, M. (TA); Ragavan, M. (TA); Tsai, J. (TA)

IMMUNOL 206: Introduction to Applied Computational Tools in Immunology

Introduction to the major underpinnings of systems immunology: first principles of development of computational approaches to immunological questions and research; aspects of study design and analysis of data sets; literature and quantifying effects sizes as applied to clinical trial design. Final projects: individual and team reviewed grant proposals (1 unit); individual or team development of grant proposals into projects and journal articles (2 units).
Terms: Spr | Units: 1-2
Instructors: ; Maecker, H. (PI)

IMMUNOL 206B: Directed Projects in Systems and Computational Immunology

Independent and team grant proposals, developed in Immunol 206A, will continue on as projects and contribute to ongoing research. Number of units assigned dependent upon the difficulty of and time spent on the project. May be repeated for credit.
Terms: Aut, Win | Units: 3-10 | Repeatable 20 times (up to 60 units total)
Instructors: ; Butte, A. (PI); Davis, M. (PI); Kotecha, N. (PI)

IMMUNOL 209: Translational Immunology

(Open to medical students in the Immunology concentration, graduate students, undergraduates by consent of instructor) Journal style format focusing on current basic immunology research and how it is translated into immunotherapies and clinical trials. Topics include hematopoiesis, transplantation, tolerance, immune monitoring, vaccination, autoimmunity and antibodies, rheumatoid arthritis, chronic pulmonary disease, and asthma. May be repeated for credit.
Terms: Aut, Win, Spr | Units: 1 | Repeatable for credit
Instructors: ; Miklos, D. (PI)

IMMUNOL 210: Immunology Research Seminars for Medical Students

Required for medical students selecting the Immunology Concentration. Attendance at a minimum of ten seminars related to immunology outside of required medical school classes. A one-page essay on each seminar, what was presented and how it relates to a clinical immunologic problem, is required.
Terms: Win, Spr | Units: 2 | Repeatable for credit
Instructors: ; Miklos, D. (PI)

IMMUNOL 215: Principles of Biological Technologies (MI 215)

The principles underlying novel as well as commonly utilized techniques to answer biological questions. Lectures and primary literature critiques on topics such as fluorescence microscopy, including applications such as FRET and single-cell analysis; human and murine genetic analysis; FACS; proteomics and analysis of noncoding RNAs. Class participation is emphasized. Prerequisite: biochemistry. Required of first-year graduate students in Microbiology and Immunology and the Immunology program.
Terms: Spr | Units: 3
Instructors: ; Sarnow, P. (PI)

IMMUNOL 260: HIV: The Virus, the Disease, the Research (MED 260)

Open to medical students, graduate students in biological sciences, undergraduates with strong biological background. Topics: immunopathogenesis immune deficits, opportunistic infections including TB, and malignancies; genomics viral genetic analyses that have traced the origin of HIV-1 and HIV-2 to primates, dated the spread of infection in humans, and characterized the evolution of the virus within infected individuals; antiretroviral drug development identification of drug targets, structure-based drug design, overcoming drug resistance, pivotal clinical trials, and role of community activism; clinical management solutions in high- and low-income countries; vaccine development learning from past failures and the future of engineering the human immune response. 4 units includes a final project assigned in consultation with the instructor to fit the individual student's background and area of HIV interest.
| Units: 3-4

IMMUNOL 280: Early Clinical Experience in Immunology

Clinical observation experience for medical students in the Immunology Scholarly Concentration. At the end of the observation period, which may span over one to two quarters, the student submits a case observation paper to his/her faculty sponsor. Prerequisite: IMMUNOL 205.
Terms: Aut, Win, Spr, Sum | Units: 1-3 | Repeatable for credit
Instructors: ; Alizadeh, A. (PI); Arvin, A. (PI); Bendall, S. (PI); Blish, C. (PI); Bollyky, P. (PI); Boothroyd, J. (PI); Butcher, E. (PI); Butte, A. (PI); Butte, M. (PI); Chen, C. (PI); Chien, Y. (PI); Chu, G. (PI); Cleary, M. (PI); Contag, C. (PI); Crabtree, G. (PI); Davis, M. (PI); Dhabhar, F. (PI); Engleman, E. (PI); Fathman, C. (PI); Felsher, D. (PI); Fontaine, M. (PI); Galli, S. (PI); Garcia, C. (PI); Goronzy, J. (PI); Habtezion, A. (PI); Han, M. (PI); Herzenberg, L. (PI); Hsieh, M. (PI); Idoyaga, J. (PI); Jones, P. (PI); Kim, P. (PI); Krams, S. (PI); Kuo, C. (PI); Lee, P. (PI); Levy, R. (PI); Levy, S. (PI); Lewis, D. (PI); Lewis, R. (PI); Majeti, R. (PI); Martinez, O. (PI); McDevitt, H. (PI); Mellins, E. (PI); Meyer, E. (PI); Michie, S. (PI); Mignot, E. (PI); Miklos, D. (PI); Monack, D. (PI); Nadeau, K. (PI); Negrin, R. (PI); Nicolls, M. (PI); Nolan, G. (PI); Palmer, T. (PI); Parham, P. (PI); Robinson, B. (PI); Sarwal, M. (PI); Schneider, D. (PI); Shafer, R. (PI); Shizuru, J. (PI); Sobel, R. (PI); Steinman, L. (PI); Strober, S. (PI); Sunwoo, J. (PI); Utz, P. (PI); Weissman, I. (PI); Weyand, C. (PI); Wu, J. (PI); Wyss-Coray, T. (PI); Jones, D. (GP)

IMMUNOL 290: Teaching in Immunology

Practical experience in teaching by serving as a teaching assistant in an immunology course. Unit values are allotted individually to reflect the level of teaching responsibility assigned to the student. May be repeated for credit.
Terms: Aut, Win, Spr, Sum | Units: 1-15 | Repeatable for credit
Instructors: ; Alizadeh, A. (PI); Arvin, A. (PI); Bendall, S. (PI); Blish, C. (PI); Bollyky, P. (PI); Boothroyd, J. (PI); Butcher, E. (PI); Butte, A. (PI); Butte, M. (PI); Chen, C. (PI); Chien, Y. (PI); Chu, G. (PI); Cleary, M. (PI); Contag, C. (PI); Crabtree, G. (PI); Davis, M. (PI); Dhabhar, F. (PI); Engleman, E. (PI); Fathman, C. (PI); Felsher, D. (PI); Fontaine, M. (PI); Galli, S. (PI); Garcia, C. (PI); Goronzy, J. (PI); Habtezion, A. (PI); Han, M. (PI); Herzenberg, L. (PI); Hsieh, M. (PI); Idoyaga, J. (PI); Jones, P. (PI); Khatri, P. (PI); Kim, P. (PI); Kohrt, H. (PI); Krams, S. (PI); Kuo, C. (PI); Lee, P. (PI); Levy, R. (PI); Levy, S. (PI); Lewis, D. (PI); Lewis, R. (PI); Maecker, H. (PI); Majeti, R. (PI); Mallick, P. (PI); Martinez, O. (PI); McDevitt, H. (PI); Mellins, E. (PI); Meyer, E. (PI); Michie, S. (PI); Mignot, E. (PI); Miklos, D. (PI); Monack, D. (PI); Nadeau, K. (PI); Negrin, R. (PI); Nicolls, M. (PI); Nolan, G. (PI); Palmer, T. (PI); Parham, P. (PI); Robinson, B. (PI); Sarwal, M. (PI); Schneider, D. (PI); Shafer, R. (PI); Shizuru, J. (PI); Sobel, R. (PI); Steinman, L. (PI); Strober, S. (PI); Sunwoo, J. (PI); Utz, P. (PI); Weissman, I. (PI); Weyand, C. (PI); Wu, J. (PI); Wyss-Coray, T. (PI); Jones, D. (GP)

IMMUNOL 299: Directed Reading in Immunology

Prerequisite: consent of instructor.
Terms: Aut, Win, Spr, Sum | Units: 1-18 | Repeatable for credit
Instructors: ; Alizadeh, A. (PI); Arvin, A. (PI); Bendall, S. (PI); Blish, C. (PI); Bollyky, P. (PI); Boothroyd, J. (PI); Butcher, E. (PI); Butte, A. (PI); Butte, M. (PI); Chen, C. (PI); Chien, Y. (PI); Chu, G. (PI); Cleary, M. (PI); Contag, C. (PI); Crabtree, G. (PI); Davis, M. (PI); Dhabhar, F. (PI); Engleman, E. (PI); Fathman, C. (PI); Felsher, D. (PI); Fontaine, M. (PI); Galli, S. (PI); Garcia, C. (PI); Goronzy, J. (PI); Habtezion, A. (PI); Herzenberg, L. (PI); Hsieh, M. (PI); Idoyaga, J. (PI); Jones, P. (PI); Kim, P. (PI); Krams, S. (PI); Kuo, C. (PI); Lee, P. (PI); Levy, R. (PI); Levy, S. (PI); Lewis, D. (PI); Lewis, R. (PI); Majeti, R. (PI); Martinez, O. (PI); McDevitt, H. (PI); Mellins, E. (PI); Meyer, E. (PI); Michie, S. (PI); Mignot, E. (PI); Miklos, D. (PI); Monack, D. (PI); Nadeau, K. (PI); Negrin, R. (PI); Nicolls, M. (PI); Nolan, G. (PI); Palmer, T. (PI); Parham, P. (PI); Robinson, B. (PI); Sarwal, M. (PI); Schneider, D. (PI); Shafer, R. (PI); Shizuru, J. (PI); Sobel, R. (PI); Steinman, L. (PI); Strober, S. (PI); Sunwoo, J. (PI); Utz, P. (PI); Weissman, I. (PI); Weyand, C. (PI); Wu, J. (PI); Wyss-Coray, T. (PI); Jones, D. (GP)

IMMUNOL 305: Immunology Journal Club

Required of first- to fourth-year graduate students. Graduate students present and discuss recent papers in the literature. May be repeated for credit.
Terms: Aut, Win, Spr | Units: 1 | Repeatable for credit
Instructors: ; Martinez, O. (PI)

IMMUNOL 310: Seminars in Computational and Systems Immunology

Presentation of CSI technologies from recent literature. Discussion of emerging application areas and limitations. Dissemination of computational resources.
Terms: Win, Sum | Units: 1 | Repeatable for credit (up to 99 units total)

IMMUNOL 311: Seminar in Immunology

Enrollment limited to Ph.D., M.D./Ph.D., and medical students whose scholarly concentrations are in Immunology. Current research topics.
Terms: Aut, Win, Spr | Units: 1 | Repeatable for credit
Instructors: ; Alizadeh, A. (PI); Martinez, O. (PI); Strauss-Albee, D. (PI); Panganiban, M. (GP); Strauss-Albee, D. (TA)

IMMUNOL 311A: Discussions in Immunology

Students discuss papers of speakers in 311, and meet with the speakers. Corequisite: 311.
Terms: Aut, Win, Spr | Units: 1 | Repeatable for credit

IMMUNOL 315: Special Topics in Immunology

Format for 2014-15 is a year long (three quarter) lecture series comprising directed readings and survey study of these topics in human and mousenimmunology: cells of the immune system; innate and adaptive immunity; antibodies and antigens; histocompatibility complex; lymphocyte development and the rearrangement and expression of antigen receptor genes; T-cell and B-cell signaling and activation; immunological tolerance; transplantation; diseases caused by immune responses; allergy; congenital and acquired immunodeficiencies. Graduate students outside immunology and Postdoctoral fellows and clinical fellows are welcome.
Terms: Win, Spr | Units: 1 | Repeatable 2 times (up to 2 units total)
Instructors: ; Butte, M. (PI)

IMMUNOL 399: Graduate Research

For Ph.D., M.D./Ph.D. students, and medical students whose scholarly concentrations are in Immunology.
Terms: Aut, Win, Spr, Sum | Units: 1-15 | Repeatable for credit
Instructors: ; Alizadeh, A. (PI); Arvin, A. (PI); Bendall, S. (PI); Blish, C. (PI); Bollyky, P. (PI); Boothroyd, J. (PI); Boyd, S. (PI); Butcher, E. (PI); Butte, A. (PI); Butte, M. (PI); Carette, J. (PI); Chen, C. (PI); Chien, Y. (PI); Chu, G. (PI); Cleary, M. (PI); Contag, C. (PI); Crabtree, G. (PI); Davis, M. (PI); Dhabhar, F. (PI); Engleman, E. (PI); Fathman, C. (PI); Felsher, D. (PI); Fontaine, M. (PI); Galli, S. (PI); Garcia, C. (PI); Goronzy, J. (PI); Habtezion, A. (PI); Han, M. (PI); Herzenberg, L. (PI); Hsieh, M. (PI); Idoyaga, J. (PI); Jardetzky, T. (PI); Jones, P. (PI); Khatri, P. (PI); Kim, P. (PI); Kohrt, H. (PI); Krams, S. (PI); Kuo, C. (PI); Lee, P. (PI); Levy, R. (PI); Levy, S. (PI); Lewis, D. (PI); Lewis, R. (PI); Maecker, H. (PI); Majeti, R. (PI); Mallick, P. (PI); Martinez, O. (PI); McDevitt, H. (PI); Mellins, E. (PI); Meyer, E. (PI); Michie, S. (PI); Mignot, E. (PI); Miklos, D. (PI); Monack, D. (PI); Nadeau, K. (PI); Negrin, R. (PI); Nicolls, M. (PI); Nolan, G. (PI); Palmer, T. (PI); Parham, P. (PI); Quake, S. (PI); Robinson, B. (PI); Sarwal, M. (PI); Schneider, D. (PI); Shafer, R. (PI); Shizuru, J. (PI); Sobel, R. (PI); Steinman, L. (PI); Strober, S. (PI); Sunwoo, J. (PI); Utz, P. (PI); Weissman, I. (PI); Weyand, C. (PI); Winslow, M. (PI); Wu, J. (PI); Wyss-Coray, T. (PI); Jones, D. (GP); Panganiban, M. (GP)

IMMUNOL 801: TGR Project

Terms: Aut, Win, Spr, Sum | Units: 0 | Repeatable for credit
Instructors: ; Alizadeh, A. (PI); Arvin, A. (PI); Bendall, S. (PI); Blish, C. (PI); Bollyky, P. (PI); Boothroyd, J. (PI); Butcher, E. (PI); Butte, A. (PI); Butte, M. (PI); Chen, C. (PI); Chien, Y. (PI); Chu, G. (PI); Cleary, M. (PI); Contag, C. (PI); Crabtree, G. (PI); Davis, M. (PI); Dhabhar, F. (PI); Engleman, E. (PI); Fathman, C. (PI); Felsher, D. (PI); Fontaine, M. (PI); Galli, S. (PI); Garcia, C. (PI); Goronzy, J. (PI); Habtezion, A. (PI); Han, M. (PI); Herzenberg, L. (PI); Hsieh, M. (PI); Idoyaga, J. (PI); Jones, P. (PI); Kim, P. (PI); Krams, S. (PI); Kuo, C. (PI); Lee, P. (PI); Levy, R. (PI); Levy, S. (PI); Lewis, D. (PI); Lewis, R. (PI); Majeti, R. (PI); Martinez, O. (PI); McDevitt, H. (PI); Mellins, E. (PI); Meyer, E. (PI); Michie, S. (PI); Mignot, E. (PI); Miklos, D. (PI); Monack, D. (PI); Nadeau, K. (PI); Negrin, R. (PI); Nicolls, M. (PI); Nolan, G. (PI); Palmer, T. (PI); Parham, P. (PI); Robinson, B. (PI); Sarwal, M. (PI); Schneider, D. (PI); Shafer, R. (PI); Shizuru, J. (PI); Sobel, R. (PI); Steinman, L. (PI); Strober, S. (PI); Sunwoo, J. (PI); Utz, P. (PI); Weissman, I. (PI); Weyand, C. (PI); Wu, J. (PI); Wyss-Coray, T. (PI); Jones, D. (GP)

IMMUNOL 802: TGR Dissertation

Terms: Aut, Win, Spr, Sum | Units: 0 | Repeatable for credit
Instructors: ; Alizadeh, A. (PI); Arvin, A. (PI); Bendall, S. (PI); Blish, C. (PI); Bollyky, P. (PI); Boothroyd, J. (PI); Butcher, E. (PI); Butte, A. (PI); Butte, M. (PI); Chen, C. (PI); Chien, Y. (PI); Chu, G. (PI); Cleary, M. (PI); Contag, C. (PI); Crabtree, G. (PI); Davis, M. (PI); Dhabhar, F. (PI); Engleman, E. (PI); Fathman, C. (PI); Felsher, D. (PI); Fontaine, M. (PI); Galli, S. (PI); Garcia, C. (PI); Goronzy, J. (PI); Habtezion, A. (PI); Han, M. (PI); Herzenberg, L. (PI); Hsieh, M. (PI); Idoyaga, J. (PI); Jones, P. (PI); Kim, P. (PI); Krams, S. (PI); Kuo, C. (PI); Lee, P. (PI); Levy, R. (PI); Levy, S. (PI); Lewis, D. (PI); Lewis, R. (PI); Majeti, R. (PI); Martinez, O. (PI); McDevitt, H. (PI); Mellins, E. (PI); Meyer, E. (PI); Michie, S. (PI); Mignot, E. (PI); Miklos, D. (PI); Monack, D. (PI); Nadeau, K. (PI); Negrin, R. (PI); Nicolls, M. (PI); Nolan, G. (PI); Palmer, T. (PI); Parham, P. (PI); Robinson, B. (PI); Sarwal, M. (PI); Schneider, D. (PI); Shafer, R. (PI); Shizuru, J. (PI); Sobel, R. (PI); Steinman, L. (PI); Strober, S. (PI); Sunwoo, J. (PI); Utz, P. (PI); Weissman, I. (PI); Weyand, C. (PI); Wu, J. (PI); Wyss-Coray, T. (PI); Jones, D. (GP)

IMMUNOL 204: Innate Immunology (MI 104, MI 204)

Innate immune mechanisms as the only defenses used by the majority of multicellular organisms. Topics include Toll signaling, NK cells, complement, antimicrobial peptides, phagocytes, neuroimmunity, community responses to infection, and the role of native flora in immunity. How microbes induce and defeat innate immune reactions, including examples from vertebrates, invertebrates, and plants.
| Units: 3

IMMUNOL 207: Essential Methods in Computational and Systems Immunology

Introduction to the major underpinnings of systems immunology: first principles of development of computational approaches to immunological questions and research; details of the algorithms and statistical principles underlying commonly used tools; aspects of study design and analysis of data sets. Prerequisites: CS106a and CS161 strongly recommended.
| Units: 3

IMMUNOL 231: Medicine for Innovators and Entrepreneurs (PEDS 231)

Interdisciplinary, project-based course in which bioscience, bioinformatics, biodesign, bioengineering students learn concepts and principles to understand human disease and work together to propose solutions to medical problems. Diabetes mellitus is used as a paradigm for understanding human disease. Guest medical school and outside faculty. Field trips to Stanford clinics and biotechnology companies. Prequisite: college level biology.
| Units: 3-4

IMMUNOL 275: Tumor Immunology (CBIO 275)

Focuses on the ability of innate and adaptive immune responses to recognize and control tumor growth. Topics include: tumor antigens, tumor immunosurveillance and immunoediting, tumor immunotherapy, cancer vaccines and dendritic cell therapy. Tracks the historical developments of our understanding of modulating tumor immune response and discusses their relative significance in the light of current research findings. Prerequisite: for undergraduates, human biology or biology core.
| Units: 3
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