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1 - 10 of 105 results for: BIOS

BIOS 200: Foundations in Experimental Biology

This course is divided into two 3-week cycles. During the first cycle, students will be developing a 2-page original research proposal, which may be used for NSF or other fellowship applications. In the second cycle, students will work in small teams and will be mentored by faculty to develop an original research project for oral presentation. Skills emphasized include: 1) reading for breadth and depth; 2) developing compelling, creative arguments; 3) communicating with the spoken and written word; 4) working in teams. Important features of the course include peer assessment, interactive joint classes, and substantial face-to-face discussion with faculty drawn from across the Biosciences programs. Shortened autumn quarter class; class meets during weeks 1 through 8 of the quarter.
Terms: Aut | Units: 5

BIOS 201: Next Generation Sequencing and Applications

Usher in the golden age of biological discovery with next generation sequencing (NGS) through its wide spectrum of applications. Modules include general introduction of Next Generation Sequencing (NGS) technologies, applications of these sequencing technologies, caveats and comparisons with previous approaches, analysis and interpretation of sequencing data, principles of tools and resources and practical ways to utilize them, and features and pitfalls. Prerequisite: background in molecular biology.
Last offered: Winter 2020

BIOS 202: Understanding Kinetics for Biologists and Biology

Students in the biological and chemical sciences are typically exposed to the kinetic and thermodynamic formalisms that describe rate and equilibrium processes, but rarely develop an intuition that allows them to use the material creatively in their own research. This Mini-course is designed to help each student begin to develop this intuition and an ability to evaluate the literature and their own data in terms of kinetic and thermodynamic models. This will be achieved through a combination of interactive lectures, in-class problem-solving, and a tutorial problem set that can be completed individually or in groups.
Last offered: Autumn 2022

BIOS 203: Market Design and Field Experiments for Health Policy and Medicine

This course will provide the student with the necessary tools to be an avid consumer and user, and potentially a producer, of the market design and field experimental literature (recognized by 4 recent Nobel Prizes in Economics: 2007/2012/2019/2020). In the first part, we introduce use of economic theory and analysis to design allocation mechanisms and market institutions, examples include medical resident matching and kidney exchanges. In the second part, it will provide a summary of recent experimental techniques deployed for both research and practice in economics, health/public policy and tech, and detail how to practically gather and analyze data using experimental methods. Emphasis on connecting to practical applications.
Last offered: Spring 2022

BIOS 204: Modeling Cell Signaling

Basics of ordinary differential equation modeling of signal transduction motifs, small circuits of regulatory proteins and genes that serve as building blocks of complex regulatory circuits. Morning session covers numerical modeling experiments. Afternoon session explores theory underpinning that day's modeling session. Modeling done using Mathematica, Standard Edition provided to enrolled students.
Terms: Aut | Units: 3
Instructors: Ferrell, J. (PI)

BIOS 207: Just Enough Software Engineering

This two week mini-course teaches the software engineering skills relevant to scientific analysis. Students will learn essential skills to promote collaboration, reproducibility, and reliability. Topics: reproducible research compendia. Modular architecture. Documenting data, code, and tools. Debugging, defensive programming, and unit tests. Prerequisites: familiarity with R.
Last offered: Autumn 2021 | Repeatable 3 times (up to 6 units total)

BIOS 208: Geometry for biologists

This 3-week mini-course offers a short series of lectures and lab workshops to enable researchers working with biological systems to build and play with geometric models of living processes. Lectures will be aimed at getting participants acquainted with fundamentals of differential geometry through examples of biological structures including filaments, membranes, and tissues. We will introduce the framework of discrete differential geometry with focus on numerically simulating differential equations describing curved geometries. Lab workshops will be aimed at playing with toy problems that utilize available open-source tools. Basic understanding of calculus, and differential equations, and some coding experience would be useful.
Last offered: Summer 2023

BIOS 209: CTS200-Statistical Design of Experiments for Bioscience

Design of experiment (DOE) techniques are used in a variety of experimental situations to collect and analyze data. In this course, principles of DOE, analytical tools, as well as experimental strategies such as screening designs, full and fractional- factorial designs such as Response surface methods (RSM) will be covered. The applications of these methodologies for optimizing responses and analyzing experimental parameters will be discussed in case studies, specifically for bioscience-related systems. Related statistical software tools such as JMPs will be introduced.
Last offered: Autumn 2021

BIOS 210: Cell, Gene, and Immune Therapies

The emerging therapeutic landscape has a new cast of characters' engineered cells, programmable nucleic acids, and multi-valent antibodies' to name a few. This lecture-based course will provide an overview of these new therapeutic modalities, the basic science guiding their development, and a discussion of new regulatory and safety challenges that emerge in these modalities. As a final project, students will produce a report spanning the preclinical and clinical development of a new therapy. Examples include CRISPR-edited cell therapies, bispecific T cell engagers, in vivo CRISPR base editors, and antisense oligo therapies.
Terms: Spr | Units: 1-2

BIOS 211: No Pride in Stigma: Exploring viral outbreaks and the stigmas perpetuated against LGBTQ+ communities

This three week mini-course explores virology, emergent outbreaks, and related stigma that has historically and perpetually impacted LGBTQ+ communities. Using lectures and open discussions, students will explore how significant viruses and related stigmas have shaped LGBTQ+ communities from a historical/academic perspective and the generational perspective through lived experiences. Join us on a queer journey through the past and present, and look forward with discussions on how we as LGBTQ+ scientists, practitioners, and allies can shape the future.
Last offered: Spring 2023
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