1 - 10 of 64 results for: BIOE

Principles of statistical physics and thermodynamics, with applications to molecular biology. Topics include entropy, temperature, free energy, chemical forces, self assembly, cooperative transitions in macromolecules, enzyme kinetics, molecular machines, and an introduction to genomic and proteomic technologies. Corequisite: BIO 41. Prerequisites: MATH 41, 42; CME 100; PHY 41; CHEM 31A, B (or 31X); CS106; or instructor approval.

Principles of transport, continuum mechanics, and fluids, with applications to cell biology. Topics include random walks, diffusion, Langevin dynamics, transport theory, low Reynolds number flow, and beam theory, with applications including quantitative models of protein trafficking in the cell, mechanics of the cell cytoskeleton, the effects of molecular noise in development, the electromagnetics of nerve impulses, and an introduction to cardiovascular fluid flow. Corequisite: BIO 42. Prerequisites: BIOE 41; MATH 41, 42; CME 100, 102; PHYSICS 41, 43; CHEM31 A,B, or 31X; CS106; or consent of instructor.

Introduction to next-generation techniques in genetic, molecular, biochemical, and cellular engineering. Lab modules build upon current research including: gene and genome engineering via decoupled design and construction of genetic material; component engineering focusing on molecular design and quantitative analysis of experiments; device and system engineering using abstracted genetically encoded objects; and product development based on useful applications of biological technologies. Limited enrollment. Priority given to majors.

Fundamental human anatomy, spanning major body systems and tissues including nerve, muscle, bone, cardiovascular, respiratory, gastrointestinal, and renal systems. Explore intricacies of structure and function, and how various body parts come together to form a coherent and adaptable living being. Correlate clinical conditions and therapeutic interventions. Participate in lab sessions with predissected cadaveric material and hands-on learning to gain understanding of the bioengineering human application domain. Encourage anatomical thinking, defining challenges and opportunities for bioengineers.

Preference to sophomores. Survey of innovative technologies and medical devices used in multiple medical specialties. Guest lecturers include Stanford Medical School physicians, entrepreneurs, and venture capitalists. Focus on how to identify clinical needs and design device solutions to address those needs. Fundamentals of starting a company. Field trips to local medical device companies and design house. No previous engineering training required.

Overview of biological engineering focused on engineering analysis and design of biological processes. Topics include overall material and energy balances, rates of biochemical reactions and processes, genetic programming of biological systems, links between information and function, and technologies to probe and manipulate biological systems. Applications of these concepts to areas of current technological importance, including biotechnology, biosynthesis, molecular/cellular therapeutics, and personalized medicine and gene therapy.

Complex biological behaviors through the integration of computational modeling and molecular biology. Topics: reconstructing biological networks from high-throughput data and knowledge bases. Network properties. Computational modeling of network behaviors at the small and large scale. Using model predictions to guide an experimental program. Robustness, noise, and cellular variation. Prerequisites: CME 102; BIO 41, 42; or instructor approval.

Biological and electrical design principles. Engineering tools used to electrically probe and model physiological systems. Basic and clinical excitable cell physiology. Topics: single-cell physiology (treatment of cells as bioelectrical devices, cable properties, ion channels and gradients, nonlinear dynamics of action potentials), network physiology and system design (neural networks, orderly recruitment of axons, Hebbian and spike timing-dependent plasticity), and excitable cell disease and interventions (major neurological and neuromuscular disease syndromes, neuromuscular simulation and surgical planning, electromagnetic stimulation instrumentation, optogenetics, tissue engineering). Prerequisites: MATH 41, 42; CME 102; PHY 41, 43; BIO 41, 42; or instructor approval.

Preference to freshmen. The biomechanics and mechanobiology of the musculoskeletal system in human beings and other vertebrates on the level of the whole organism, organ systems, tissues, and cell biology. Field trips to labs.