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21 - 30 of 233 results for: all courses

BIO 44X: Core Molecular Biology Laboratory

Investigate yeast strains that are engineered to express the human protein, p53, and use modern molecular methods to identify the functional consequences of p53 mutations isolated from tumor cells. Learn about the protein's role as a tumor suppressor through lectures and by reading and discussing journal articles. Use molecular visualization programs to examine the structure of wild type and mutant p53 proteins. Formulate a testable hypothesis and assay the ability of mutant p53 to direct expression of several reporter genes. During guided reflection, formulate further analyses to determine whether mutant p53 is present in the cell, can bind to DNA, and/or can enter the nucleus. Conduct lab experiments, present findings through a team oral presentation, as well as a scientific poster. Prerequisites: CHEM 31X, or 31A,B, and 33; concurrent or past enrollment in Biology or Human Biology core. 44X,Y should be taken sequentially in the same year, preferably as sophomores, to prepare for internships. Preference given to juniors and seniors in fall quarter, preference given to sophomores in winter quarter. Lab fee. Information about this class is available at http://bio44.stanford.edu.
Terms: Aut, Win | Units: 5 | UG Reqs: WAY-SMA

BIO 44Y: Core Plant Biology & Eco Evo Laboratory

The goal of this course is to develop an understanding of how to conduct biological research, using a topic in Ecology, Evolutionary Biology, and Plant Biology as a practical example. This includes the complete scientific process: assessing background literature, generating testable hypotheses, learning techniques for field- and lab-based data collection, analyzing data using appropriate statistical methods, and finally writing and sharing results. To build these skills, this course will focus on communities of microorganisms living in floral nectar at Stanford's nearby Jasper Ridge Biological Preserve. Students, working in teams, will develop novel research hypotheses and execute the necessary experiments and measurements to test these hypotheses. The capstone of the course will be an oral defense of students' findings, as well as a research paper in the style of a peer-reviewed journal article. Labs will be completed both on campus and at Jasper Ridge. Lab fee. Information about this class is available at http://bio44.stanford.edu.
Terms: Spr | Units: 5 | UG Reqs: WAY-SMA

BIO 109A: The Human Genome and Disease (BIO 209A, BIOC 109A, BIOC 209A, HUMBIO 158)

The variability of the human genome and the role of genomic information in research, drug discovery, and human health. Concepts and interpretations of genomic markers in medical research and real life applications. Human genomes in diverse populations. Original contributions from thought leaders in academia and industry and interaction between students and guest lecturers. Students with a major, minor or coterm in Biology: 109A/209A or 109B/209B may count toward degree program but not both.
Terms: Win | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIO 109B: The Human Genome and Disease: Genetic Diversity and Personalized Medicine (BIO 209B, BIOC 109B, BIOC 209B)

Continuation of 109A/209A. Genetic drift: the path of human predecessors out of Africa to Europe and then either through Asia to Australia or through northern Russia to Alaska down to the W. Coast of the Americas. Support for this idea through the histocompatibility genes and genetic sequences that predispose people to diseases. Guest lectures from academia and pharmaceutical companies. Prerequisite: Biology or Human Biology core. Students with a major, minor or coterm in Biology: 109A/209A or 109B/209B may count toward degree program but not both.
Terms: Spr | Units: 3 | UG Reqs: WAY-SMA, GER: DB-NatSci

BIO 110: DNA Replication and Genomic Maintenance (BIO 210)

Maintenance of the genome and its accurate replication are prerequisites for life. DNA replication is also intricately connected to pathways for responding to genotoxic stress, which include inevitable collisions with transcription. In eukaryotes, DNA repair and replication are tightly connected to chromatin modification. Emphasis for lecture topics include: DNA-templated chromatin transactions; Chromatin manipulation during replication and DNA damage responses; Structural biology and molecular mechanisms of replication and DNA repair enzymes; Inducible responses to genotoxic stress; Relationships of DNA damage processing to mutagenesis, carcinogenesis, aging and human genetic disease.
Terms: Spr | Units: 3 | UG Reqs: WAY-SMA, GER: DB-NatSci

BIO 117: Biology and Global Change (EARTHSYS 111, EESS 111)

The biological causes and consequences of anthropogenic and natural changes in the atmosphere, oceans, and terrestrial and freshwater ecosystems. Topics: glacial cycles and marine circulation, greenhouse gases and climate change, tropical deforestation and species extinctions, and human population growth and resource use. Prerequisite: Biology or Human Biology core or graduate standing.
Terms: Win | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIO 118: Genetic Analysis of Biological Processes (BIO 218)

Genetic principles and their experimental applications. Emphasis is on the identification and use of mutations to study cellular function. Satisfies Central Menu Areas 1 or 2. Prerequisite: Biology core.
Terms: Win | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIO 121: Biogeography

Global distributions of organisms through the Phanerozoic, with emphasis on historical causes. Topics: plate tectonics, island biogeography, climatic change, dispersal, vicariance, ecology of invasions, extinction, gradients, diversity. Satisfies Central Menu Area 4.
Last offered: Spring 2009 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIO 129A: Cellular Dynamics I: Cell Motility and Adhesion

Cell motility emphasizing role of actin assembly and dynamics coupling actin organization to cell movement. Interaction of cells with extracellular matrix, and remodelling of extracellular matrix in development and disease. Directed cell migration by chemotaxis (neuronal path-finding, immune cells). Cell-cell adhesion, formation of intercellular junctions and mechanisms regulating cell-cell interactions in development and diseases. Emphasis is on experimental logic, methods, problem solving, and interpretation of results. Students present research papers. Satisfies Central Menu Area 2. Prerequisite: Biology core.
Terms: Win | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-AQR, WAY-SMA

BIO 136: Evolutionary Paleobiology

A paleontological approach to evolutionary theory. Topics: history of life, speciation, heterochrony, evolutionary constraint, coevolution, macroevolution, the Cambrian Explosion, mass extinctions, taphonomy, life on land, life in the sea, life in the air. Satisfies Central Menu Area 4. Prerequisite: Biology Core.
Last offered: Winter 2011 | UG Reqs: GER: DB-NatSci, WAY-SMA
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