printer friendly pageBIO 104: Advanced Molecular Biology (BIO 200)
Molecular mechanisms that govern the replication, recombination, and expression of eukaryotic genomes. Topics: DNA replication, DNA recombination, gene transcription, RNA splicing, regulation of gene expression, protein synthesis, and protein folding. Satisfies Central Menu Area 1. Prerequisite: Biology core.
Terms: Win
| Units: 5
| UG Reqs: GER: DB-NatSci
Instructors:
Gozani, O. (PI)
;
Dorone, Y. (TA)
;
Flores Servin, J. (TA)
...
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Instructors:
Gozani, O. (PI)
;
Dorone, Y. (TA)
;
Flores Servin, J. (TA)
;
Husmann, D. (TA)
;
Sankaran, S. (TA)
BIO 109A: The Human Genome and Disease (BIOC 109A, BIOC 209A, HUMBIO 158)
The variability of the human genome and the role of genomic information in research, drug discovery, and human health. Concepts and interpretations of genomic markers in medical research and real life applications. Human genomes in diverse populations. Original contributions from thought leaders in academia and industry and interaction between students and guest lecturers. Students with a major, minor or coterm in Biology: 109A/209A or 109B/209B may count toward degree program but not both.
Terms: Win
| Units: 3
| UG Reqs: GER: DB-NatSci, WAY-SMA
BIO 109B: The Human Genome and Disease: Genetic Diversity and Personalized Medicine (BIOC 109B, BIOC 209B)
Continuation of 109A/209A. Genetic drift: the path of human predecessors out of Africa to Europe and then either through Asia to Australia or through northern Russia to Alaska down to the W. Coast of the Americas. Support for this idea through the histocompatibility genes and genetic sequences that predispose people to diseases. Guest lectures from academia and pharmaceutical companies. Prerequisite: Biology or Human Biology core. Students with a major, minor or coterm in Biology: 109A/209A or 109B/209B may count toward degree program but not both.
Terms: Spr
| Units: 3
| UG Reqs: WAY-SMA, GER: DB-NatSci
Instructors:
Goeders, C. (PI)
;
Heller, R. (PI)
BIO 110: DNA Replication and Genomic Maintenance (BIO 210)
Maintenance of the genome and its accurate replication are prerequisites for life. DNA replication is also intricately connected to pathways for responding to genotoxic stress, which include inevitable collisions with transcription. In eukaryotes, DNA repair and replication are tightly connected to chromatin modification. Emphasis for lecture topics include: DNA-templated chromatin transactions; Chromatin manipulation during replication and DNA damage responses; Structural biology and molecular mechanisms of replication and DNA repair enzymes; Inducible responses to genotoxic stress; Relationships of DNA damage processing to mutagenesis, carcinogenesis, aging and human genetic disease.
Last offered: Spring 2014
| UG Reqs: GER: DB-NatSci, WAY-SMA
BIO 112: Human Physiology (HUMBIO 133)
Human physiology will be examined by organ systems: respiratory, cardiovascular, renal, and gastrointestinal. Concepts of cell and molecular biology that underlie organ development, pathophysiology and opportunities for regenerative medicine will be introduced. Signaling and integrative control by the endocrine, autonomic and central nervous systems will be introduced. Prerequisite: Biology or Human Biology core.
Terms: Win
| Units: 4
| UG Reqs: GER: DB-NatSci
Instructors:
Kao, P. (PI)
;
Hamaguchi, R. (TA)
BIO 113: Fundamentals of Molecular Evolution (BIO 244)
The inference of key molecular evolutionary processes from DNA and protein sequences. Topics include random genetic drift, coalescent models, effects and tests of natural selection, combined effects of linkage and natural selection, codon bias and genome evolution. Satisfies Central Menu Areas 1 or 4. Prerequisites: Biology core or graduate standing in any department, and consent of instructor.
Terms: Win
| Units: 4
| UG Reqs: GER: DB-NatSci
BIO 116: Ecology of the Hawaiian Islands (EARTHSYS 116)
Terrestrial and marine ecology and conservation biology of the Hawaiian Archipelago. Taught in the field in Hawaii as part of quarter-long sequence of courses including Earth Sciences and Anthropology. Topics include ecological succession, plant-soil interactions, conservation biology, biological invasions and ecosystem consequences, and coral reef ecology. Restricted to students accepted into the Earth Systems of Hawaii Program.
Terms: Aut
| Units: 4
| UG Reqs: GER: DB-NatSci
BIO 117: Biology and Global Change (EARTHSYS 111, EESS 111)
The biological causes and consequences of anthropogenic and natural changes in the atmosphere, oceans, and terrestrial and freshwater ecosystems. Topics: glacial cycles and marine circulation, greenhouse gases and climate change, tropical deforestation and species extinctions, and human population growth and resource use. Prerequisite: Biology or Human Biology core or graduate standing.
Terms: Win
| Units: 4
| UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors:
Arrigo, K. (PI)
;
Vitousek, P. (PI)
BIO 118: Genetic Analysis of Biological Processes
Focus is on using mutations and genetic analysis to study biological and medical questions. The first portion of the course covers how the identification and analysis of mutations can be used in model systems to investigate biological processes such as development and metabolism. In the second portion of the course, we focus on the use of existing genetic variation in humans and other species to identify disease-associated genes as well as to investigate variation in morphological traits such as body size and shape.
Terms: Win
| Units: 4
| UG Reqs: GER: DB-NatSci, WAY-SMA
BIO 121: Biogeography
Global distributions of organisms through the Phanerozoic, with emphasis on historical causes. Topics: plate tectonics, island biogeography, climatic change, dispersal, vicariance, ecology of invasions, extinction, gradients, diversity. Satisfies Central Menu Area 4.
Last offered: Spring 2009
| UG Reqs: GER: DB-NatSci, WAY-SMA
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