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1 - 10 of 18 results for: PATH

PATH 101: Cancer Biology (CBIO 101)

Experimental approaches to understanding the origins, diagnosis, and treatment of cancer. Focus on key experiments and discoveries with emphasis on genetics, molecular biology, and cell biology. Topics include carcinogens, tumor virology, oncogenes, tumor suppressor genes, cell cycle regulation, angiogenesis, invasion and metastasis, cancer genomics, cancer epidemiology, and cancer therapies. Discussion sections based on primary research articles that describe key experiments in the field. Prerequisite: Biology or Human Biology core or equivalent, or consent of instructor.
Terms: Win | Units: 4
Instructors: Lipsick, J. (PI)

PATH 103Q: Lymphocyte Migration

Preference to sophomores. How lymphocytes leave the blood stream and enter tissues to participate in immune surveillance and the development of inflammation. Known as lymphocyte migration, this process involves a complex series of adhesion, activation and diapedesis events. The cellular mechanisms involved in lymphocyte migration, including lymphocyte adhesion molecules that interact with their counter-receptors on endothelial cells, and molecules, including cytokines and chemokines, that attract or activate lymphocytes. The roles of these molecules in the development of human diseases such as asthma, type 1 diabetes, and multiple sclerosis.
Terms: Aut | Units: 1
Instructors: Michie, S. (PI)

PATH 105Q: Final Analysis: The Autopsy as a Tool of Medical Inquiry

Preference to sophomores. Based on review of patient medical histories and examination of formalin-fixed and unfixed tissues from autopsy. Student-directed problem-solving; students develop learning objectives for each case, and present findings. The effect of disease on normal structure and function, ethics of patient care, allocation of medical resources, efficiency of therapy, and medical error. Prerequisite: hepatitis-B vaccination; free vaccinations during the winter for accepted students. Deadline to apply is noon, November 30, 2009.
Terms: Spr | Units: 3
Instructors: Connolly, A. (PI)

PATH 199: Undergraduate Research

Students undertake investigations sponsored by individual faculty members. Prerequisite: consent of instructor.
Terms: Aut, Win, Spr, Sum | Units: 1-18 | Repeatable for credit

PATH 206: Epigenetics (BIO 156, BIO 256, GENE 206)

Terms: Spr | Units: 2

PATH 210: Stem Cells in Development and Disease

Molecular and cellular mechanisms underlying the basic self-renewal and differentiation properties of stem cells in multiple tissues and organisms. How abnormal stem cell behavior may contribute to diseases such as cancer. How to manipulate stem cell behavior in vitro or in vivo for therapeutic purposes. Classical papers and recent literatures in the field of stem cell biology. Open to graduate, medical, and advanced undergraduate students. Prerequisite: consent of instructor.
Terms: Aut | Units: 1-2
Instructors: Lu, B. (PI)

PATH 213: Gross Autopsy Pathology Laboratory

Examine/discuss unfixed dissected organs from current autopsies and correlate morphologic findings with the clinical history. Students view postmortem examinations and may participate (in a small group) in one postmortem examination with the assistance of residents and staff, and present the case to the class. Class scheduling is flexible. Additional unit for participation in a postmortem examination. Pre- or corequisite: HHD.
Terms: Aut, Win | Units: 2-3
Instructors: Regula, D. (PI)

PATH 234: Fundamentals of RNA Biology (GENE 234, MI 234)

For graduate or medical students and (if space allows) to active participants from other segments of the Stanford Community (e.g., TGR students); undergraduates by instructor consent. Fundamental issues of RNA biology, with the goal of setting a foundation for students to explore the expanding world of RNA-based regulation. Each week a topic is covered by a faculty lecture and journal club presentations by students.
Terms: Aut | Units: 2

PATH 235: Applications of High-Throughput Sequencing (MI 235)

Large-scale sequencing of DNA and RNA pools has greatly impacted how we think about the biology of genetic information. This lecture- and discussion-based course focuses on applications of high-throughout and ultra-high-throughout sequencing technologies. Students are introduced to currently available and soon-to-be available sequencing technologies, and to some of the pipelines available for data analysis. Discussions cover a wide repertoire of biological questions, both in basic science and clinical settings, that may be addressed using these technologies. Students are encouraged to think about ways to apply these technologies to advance their own research interests.
Terms: Win | Units: 2

PATH 240: Clinical Studies in Pathology I

Broad exposure to the practice of pathology in an academic medical center. Students are assigned a faculty mentor and work closely with pathology residents, fellows and faculty. Two months are spent in surgical pathology where students help examine surgical resection specimens and biopsies and participate in making a final diagnosis. One month is spent in autopsy pathology where students perform autopsy prosections and formulate final anatomic diagnoses under the supervision of faculty. May be combined with Clinical Studies in Pathology II, and two additional quarters of PATH 399, Directed Research, to fulfill a 12 month Post-Sophomore year Fellowship in Pathology. Prerequisite: MD candidate; instructor consent.
Terms: Aut, Win, Spr, Sum | Units: 3-9
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