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31 - 40 of 64 results for: BIOS

BIOS 231: Neuroimaging Genomics

Preference to graduate students and medical students. Emphasis is on introducing students to the field of neuroimaging genomics, characterizing large-scale genomic and imaging datasets to uncover relationships between imaging features, molecular genomic profiles, and phenotype.

BIOS 232: Two-photon Imaging of Neural Circuits

Focuses on application of two-photon imaging to modern neuroscience. Topics include microscopy and imaging.
Last offered: Winter 2016

BIOS 233: Experimental Metagenomics: Nectar Microbes as a Model System

Preference to graduate students and post-docs; open to upper-level undergraduates with instructor consent. Emphasis on developing a practical understanding of how to conduct metagenomic research by combining cutting-edge molecular sequencing with experimental ecological approaches. Focuses on the community ecology of the bacterial and yeast species that colonize floral nectar via pollinators and the implications for plant-pollinator interactions within an agriculturally relevant framework. Ecological, evolutionary, and phylogenetic principles and microbiological and molecular techniques that will be taught are broadly applicable in many biological fields, including the medical ecology of hte human microbiome. Inquiry-based with individual student-led projects.

BIOS 234: Personalized Genomic Medicine

Focuses on next-generation sequencing and its implications for personalized genomic medicine. Students gain hands-on experience with popular DNA sequence analysis tools as well as a practical understanding of the underlying algorithms and biomedicine.
Last offered: Spring 2016

BIOS 235: Metabolism and Metabolic Ecology: Microbes, Gut and Cancer

Preference to graduate students. Focuses on modern aspects of metabolism and metabolic biochemistry as it affects fitness and ecology of cells and organisms on a systems level. Students obtain a broad understanding of the governing principles and logic of metabolic pathways and their networks as well as an intuition of metabolism in context of natural selection and fitness acting on the cell or host. Emphasis is primarily on microorganisms and their habitats in nature and the human gut, but topics also include metabolism of cancer cells and of engineered microbes.
Terms: Spr | Units: 2
Instructors: Spormann, A. (PI)

BIOS 236: Developmental Biology in the Ocean: Comparative Embryology and Larval Development

Three-week course at Hopkins Marine Station. Focuses on the embryology and larval development of a broad range of marine invertebrate phyla. The goal of the course is to give students an appreciation of the range of developmental strategies and larval forms in the ocean and why this is critical for constructing hypotheses of EvoDevo and animal evolution. Includes observation and documentation of the development of embryos and larvae by scientific illustration and photo/video microscopy. Pre-requisite: Developmental Biology coursework and instructor consent.
Terms: Spr | Units: 4
Instructors: Lowe, C. (PI)

BIOS 237: Investigating Biology with Fluorescent Proteins

Focuses on fluorescent proteins, a proven research tool for imaging a wide range of biological phenomena and continuously uncover exciting discoveries in many areas. Students gain practical expertise in concepts, methodology, and data analysis through lectures, literature discussion, and hands-on computer exercises with "real world" data.
Last offered: Winter 2015

BIOS 238: Quantitative single cell analysis of live cell images

Last offered: Autumn 2014

BIOS 239: Synapse Development

Focuses on the mechanisms of synapse development, including the role of adhesion molecules in establishing neuronal contacts, the function of synapse-inducing molecules, how pre- and postsynaptic material is transported to nascent synapses, synapse maturation, synapse elimination as well as how synaptic dysfunction may lead to neurological disorders. Readings from primary literature.
Last offered: Winter 2015

BIOS 240: Cellular Metabolism: An Emerging Hallmark of Cancer and Aging

Introduction to cellular metabolism, including changes in metabolic flux that drive diverse disease states from cancer to aging. Topics covered include cancer metabolism, cellular nutrient sensing, metabolism in aging, and the influence of metabolism on stem cell fate. This course uses discussion of recent advances in the field to place an emphasis on practical applications, including the integration of metabolomics into the era of ¿Big Data¿. This mini-course culminates with a lab section allowing the students to conduct an extracellular flux experiment using the Seahorse analyzer to study changes in mitochondrial respiration and glycolysis in cancer cells.
Last offered: Winter 2015
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