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ANTHRO 171: The Biology and Evolution of Language (ANTHRO 271)

Lecture course surveying the biology, linguistic functions, and evolution of the organs of speech and speech centers in the brain, language in animals and humans, the evolution of language itself, and the roles of innateness vs. culture in language. Suitable both for general education and as preparation for further studies in anthropology, biology, linguistics, medicine, psychology, and speech & language therapy. Anthropology concentration: CS, EE. No prerequisites.
Last offered: Winter 2017 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIO 4N: The Science and Ethics of Personalized Genomic Medicine

We will explore the exciting field of personalized genomic medicine. Personalized medicine is based on the idea that each person's unique genome sequence can be used to predict their risk of developing diseases, and could perhaps even be edited using CRISPR to improve health. We will discuss the science behind these approaches; where they are heading in the future; and the ethical implications such technology presents. Student presentations will be emphasized, and students will also get to explore and analyze a real person's genome.
Terms: Win | Units: 3 | UG Reqs: GER: DB-NatSci
Instructors: Fraser, H. (PI)

BIO 8N: Human Origins

A survey of the anatomical and behavioral evidence for human evolution and of the increasingly important information from molecular genetics. Emphasis on the split between the human and chimpanzee lines 6-7 million years ago, the appearance of the australopiths by 4.1 million years ago, the emergence of the genus Homo about 2.5 million years ago, the spread of Homo from Africa 1.7-1.6 million years ago, the subsequent divergence of Homo into different species on different continents, and the expansion of fully modern humans (Homo sapiens) from Africa about 50,000 years ago to replace the Neanderthals and other non-modern Eurasians.
Last offered: Winter 2023 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIO 8S: Introduction to Human Physiology

Normal functioning and pathophysiology of major organ systems: nervous, respiratory, cardiovascular, renal, digestive, and endocrine. Additional topics include integrative physiology, clinical case studies, and applications in genomics-based personalized medicine.
Terms: Sum | Units: 4 | UG Reqs: GER: DB-NatSci
Instructors: Goeders, C. (PI)

BIO 25Q: Cystic fibrosis: from medical conundrum to precision medicine success story

The class will explore cystic fibrosis (CF), the most prevalent fatal genetic disease in the US, as a scientific and medical whodunit. Through reading and discussion of medical and scientific literature, we will tackle questions that include: how was life expectancy with CF increased from weeks to decades without understanding the disease mechanism? Why is the disease so prevalent? Is there an advantage to being a carrier? Is CF a single disease or a continuum of physiological variation; or- what is a disease? How did research into CF lead to discovery of the underlying cause of most other genetic diseases as well? Through critical reading of the scientific and medical literature, class discussion, field trips and meetings with genetic counselors, caregivers, patients, physicians and researchers, we will work to build a deep understanding of this disease, from the biochemical basis to the current controversies over pathogenic mechanisms, treatment strategies and the ethics and economics of genetic testing and astronomical drug costs.
Terms: Win | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: Kopito, R. (PI)

BIO 30: Ecology for Everyone

Ecology is the science of interactions and the changes they generate. This project-based course links individual behavior, population growth, species interactions, and ecosystem function. Introduction to measurement, observation, experimental design and hypothesis testing in field projects. The goal is to learn to think analytically about everyday ecological processes, including those that you participate in, which involve bacteria, fungi, plants, animals and humans. The course uses basic statistics to analyze data; there are no math prerequisites except arithmetic. Open to everyone, including those who may be headed for more advanced courses in ecology and environmental science. The online version will meet synchronously and involve preparation outside of class for interactive discussions during class time. We will organize field projects that you can do wherever you are. Projects begin in the first week of the quarter. For questions please contact Prof. Gordon at dmgordon@stanford.edu.
Last offered: Winter 2021 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIO 109A: Chronic Disease I: Applications of Novel Advances in Biology and Biotechnology

We have come a long way in developing therapies for chronic diseases. However, a gap remains between the current solutions and our ability to fully address these diseases. This course provides an overview of: (1) the underlying biology of many of these diseases and (2) the applications of novel advances in basic science and biotechnology to generate more effective therapies. There will be guest lectures from prominent leaders in academia and industry, and we encourage both students and speakers to seek opportunities to collaborate. No hard prerequisites, though a basic understanding of biology and willingness to learn novel concepts will help.
Last offered: Winter 2023 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIO 109B: Chronic Disease II: Applications of Advances in Precision Medicine and Digital Health Technologies

Chronic diseases fatally impact over 40 million people worldwide. We have come a long way in developing therapies for some chronic diseases, but a considerable gap remains between the current solutions and our ability to fully address many of these diseases. This course provides an overview of: (1) the underlying biology of pervasive chronic diseases and (2) the applications of advances in precision medicine and digital health technologies towards better understanding, preventing, and treating these diseases. There will also be discussions on the policy and regulatory frameworks and business and ethical implications that impact precision medicine/digital health innovations (and their potential applications). We will have guest speakers who are prominent leaders in academia, industry, and federal policy. We encourage both students and speakers to seek opportunities to collaborate. No hard prerequisites, though a basic understanding of biology and willingness to learn novel concepts will help.
Last offered: Spring 2023 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIO 110: The Chromatin-Regulated Genome (BIO 210)

Maintenance of the genome is a prerequisite for life. In eukaryotes, all DNA-templated processes are tightly connected to chromatin structure and function. This course will explore epigenetic and chromatin regulation of cellular processes related to aging, cancer, stem cell pluripotency, metabolic homeostasis, and development. Course material integrates current literature with a foundational review of histone modifications and nucleosome composition in epigenetic inheritance, transcription, replication, cell division and DNA damage responses. Prerequisite: BIO 41 or BIO 83 or consent of instructor.
Last offered: Spring 2022 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIO 112: Human Physiology (HUMBIO 133)

Human physiology will be examined by organ systems: cardiovascular, respiratory, renal, gastrointestinal and endocrine. Molecular and cell biology and signaling principles that underlie organ development, pathophysiology and opportunities for regenerative medicine are discussed, as well as integrative control mechanisms and fetal development. Prerequisite: HUMBIO3A or HUMBIO4A or BIO83 or BIO84 orBIO86 or consent of instructor.
Terms: Win | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-SMA
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