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1 - 10 of 20 results for: CSB

CSB 199: Undergraduate Research

Students undertake investigations sponsored by individual faculty members. Prerequisite: consent of instructor.
Terms: Aut, Win, Spr, Sum | Units: 1-18 | Repeatable for credit | Grading: Satisfactory/No Credit

CSB 210: Cell Signaling

The molecular mechanisms through which cells receive and respond to external signals. Emphasis is on principles of cell signaling, the systems-level properties of signal transduction modules, and experimental strategies through which cell signaling pathways are being studied. Prerequisite: working knowledge of biochemistry and genetics.
Terms: Win | Units: 4 | Grading: Medical Option (Med-Ltr-CR/NC)

CSB 220: Chemistry of Biological Processes

The principles of organic and physical chemistry as applied to biomolecules. The goal is a working knowledge of chemical principles that underlie biological processes, and chemical tools used to study and manipulate biological systems. Current topics may include chemical genetics, activity-based probes, DNA/RNA chemistry and molecular evolution, protein labeling, carbohydrate engineering, fluorescent proteins and sensors, optochemical/optogenetic methods, mass spectrometry, and genome-editing technologies. Prerequisites: organic chemistry and biochemistry, or consent of instructor.
Terms: alternate years, given next year | Units: 3 | Grading: Medical Option (Med-Ltr-CR/NC)

CSB 240A: A Practical Approach to Drug Discovery and Development

Advancing a drug from discovery of a therapeutic target to human trials and commercialization. Topics include: high throughput assay development, compound screening, lead optimization, protecting intellectual property, toxicology testing, regulatory issues, assessment of clinical need, defining the market, conducting clinical trials, project management, and commercialization issues, including approach to licensing and raising capital. Maximum units are available by taking an additional contact hour.
Terms: alternate years, given next year | Units: 3-4 | Grading: Medical Option (Med-Ltr-CR/NC)

CSB 240B: A Practical Approach to Drug Discover and Development

(Continuation of 240A) Advancing a drug from discovery of a therapeutic target to human trials and commercialization. Topics include: high throughput assay development, compound screening, lead optimization, protecting intellectual property, toxicology testing, regulatory issues, assessment of clinical need, defining the market, conducting clinical trials, project management, and commercialization issues, including approach to licensing and raising capital. Maximum units are available by taking an additional contact hour. Prerequisite: 240A.
Terms: alternate years, given next year | Units: 3-4 | Grading: Medical Option (Med-Ltr-CR/NC)

CSB 242: Drug Discovery and Development Seminar Series

The scientific principles and technologies involved in making the transition from a basic biological observation to the creation of a new drug emphasizing molecular and genetic issues. Prerequisite: biochemistry, chemistry, or bioengineering.
Terms: Aut, Win, Spr, Sum | Units: 1 | Repeatable for credit | Grading: Medical Satisfactory/No Credit

CSB 244: Drug Discovery and Development: A Case-based Approach

Provides an overview of the drug discovery and development process through use of case examples--successful and unsuccessful attempts to integrate the scientific, clinical, regulatory, and commercial requirements to bring a new drug to patients. Focus on the complex array of independent tasks that must be accomplished to bring a new drug to the clinic. Specific cases discussed in a seminar format.
Terms: alternate years, given next year | Units: 2 | Grading: Medical Option (Med-Ltr-CR/NC)

CSB 245: Economics of Biotechnology

Focuses on translation of promising research discovery into marketed drugs and the integration of scientific method, clinical needs assessment, clinical and regulatory strategy, market analysis, economic considerations, and the influence of the healthcare economic ecosystem necessary for successful translation. Explores the economic perspectives of various stakeholders--patients, providers, payers, biotechnology and pharmaceutical companies, FDA, and financial markets--and how they influence drug development.
Terms: Spr | Units: 2 | Grading: Medical Option (Med-Ltr-CR/NC)
Instructors: Grimes, K. (PI)

CSB 250: The Biology of Chromatin Templated Processes

Topics include mechanisms of DNA replication; gene expressions regulation; DNA damage sensing and DNA repair; chromatin structure and function; and epigenetics and nuclear reprogramming. Prerequisite: working knowledge of molecular biology, biochemistry and genetics, or instructor consent.
Terms: Spr | Units: 3 | Grading: Medical Option (Med-Ltr-CR/NC)
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