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1 - 10 of 19 results for: BIOPHYS

BIOPHYS 196: INTERACTIVE MEDIA AND GAMES (BIOE 196)

Interactive media and games increasingly pervade and shape our society. In addition to their dominant roles in entertainment, video games play growing roles in education, arts, and science. This seminar series brings together a diverse set of experts to provide interdisciplinary perspectives on these media regarding their history, technologies, scholarly research, industry, artistic value, and potential future.
Terms: Aut, Win, Spr | Units: 1 | Repeatable for credit | Grading: Satisfactory/No Credit

BIOPHYS 227: Functional MRI Methods (RAD 227)

Basics of functional magnetic resonance neuroimaging, including data acquisition, analysis, and experimental design. Journal club sections. Cognitive neuroscience and clinical applications. Prerequisites: basic physics, mathematics; neuroscience recommended.
Terms: Win | Units: 3 | Grading: Medical Option (Med-Ltr-CR/NC)
Instructors: Glover, G. (PI)

BIOPHYS 232: Advanced Imaging Lab in Biophysics (APPPHYS 232, BIO 132, BIO 232, GENE 232)

Laboratory and lectures. Advanced microscopy and imaging, emphasizing hands-on experience with state-of-the-art techniques. Students construct and operate working apparatus. Topics include microscope optics, Koehler illumination, contrast-generating mechanisms (bright/dark field, fluorescence, phase contrast, differential interference contrast), and resolution limits. Laboratory topics vary by year, but include single-molecule fluorescence, fluorescence resonance energy transfer, confocal microscopy, two-photon microscopy, microendoscopy, and optical trapping. Limited enrollment. Recommended: basic physics, Biology core or equivalent, and consent of instructor.
Terms: Spr | Units: 4 | Grading: Medical Option (Med-Ltr-CR/NC)

BIOPHYS 241: Biological Macromolecules (BIOC 241, GENE 241, SBIO 241)

The physical and chemical basis of macromolecular function. Topics include: forces that stabilize macromolecular structure and their complexes; thermodynamics and statistical mechanics of macromolecular folding, binding, and allostery; diffusional processes; kinetics of enzymatic processes; the relationship of these principles to practical application in experimental design and interpretation. The class emphasizes interactive learning, and is divided equally among lectures, in-class group problem solving, and discussion of current and classical literature. Enrollment limited to 50. Prerequisites: Background in biochemistry and physical chemistry recommended but material available for those with deficiency in these areas; undergraduates with consent of instructor only.
Terms: Spr | Units: 3-5 | Grading: Medical Option (Med-Ltr-CR/NC)

BIOPHYS 242: Methods in Molecular Biophysics (SBIO 242)

Experimental methods in molecular biophysics from theoretical and practical standpoints. Emphasis is on X-ray diffraction, nuclear magnetic resonance, and fluorescence spectcroscopy. Prerequisite: physical chemistry or consent of instructor.
Terms: Win, alternate years, not given next year | Units: 3 | Grading: Medical Option (Med-Ltr-CR/NC)

BIOPHYS 244: Mechanotransduction in Cells and Tissues (BIOE 283, ME 244)

Mechanical cues play a critical role in development, normal functioning of cells and tissues, and various diseases. This course will cover what is known about cellular mechanotransduction, or the processes by which living cells sense and respond to physical cues such as physiological forces or mechanical properties of the tissue microenvironment. Experimental techniques and current areas of active investigation will be highlighted.
Terms: Aut | Units: 3 | Grading: Letter or Credit/No Credit

BIOPHYS 250: Seminar in Biophysics

Required of Biophysics graduate students. Presentation of current research projects and results by faculty in the Biophysics program. May be repeated for credit.
Terms: Aut | Units: 1 | Repeatable for credit | Grading: Medical Satisfactory/No Credit
Instructors: Weis, W. (PI)

BIOPHYS 279: Computational Biology: Structure and Organization of Biomolecules and Cells (BIOE 279, BIOMEDIN 279, CME 279, CS 279)

Computational approaches to understanding the three-dimensional spatial organization of biological systems and how that organization evolves over time. The course will cover cutting-edge research in both physics-based simulations and computational analysis of experimental data, at scales ranging from individual molecules to multiple cells. Prerequisites: elementary programming background (106A or equivalent) and an introductory course in biology or biochemistry.
Terms: Aut | Units: 3 | Grading: Letter or Credit/No Credit

BIOPHYS 294: Cellular Biophysics (APPPHYS 294, BIO 294)

Physical biology of dynamical and mechanical processes in cells. Emphasis is on qualitative understanding of biological functions through quantitative analysis and simple mathematical models. Sensory transduction, signaling, adaptation, switches, molecular motors, actin and microtubules, motility, and circadian clocks. Prerequisites: differential equations and introductory statistical mechanics.
Terms: Aut, alternate years, not given next year | Units: 3 | Grading: Letter or Credit/No Credit
Instructors: Fisher, D. (PI)

BIOPHYS 297: Bio-Inorganic Chemistry (CHEM 297)

Overview of metal sites in biology. Metalloproteins as elaborated inorganic complexes, their basic coordination chemistry and bonding, unique features of the protein ligand, and the physical methods used to study active sites. Active site structures are correlated with function. Prerequisites: 153 and 173, or equivalents.
Terms: Win | Units: 3 | Grading: Letter (ABCD/NP)
Instructors: Solomon, E. (PI)
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