CSB 199: Undergraduate Research
Students undertake investigations sponsored by individual faculty members. Prerequisite: consent of instructor.
Terms: Aut, Win, Spr, Sum
| Units: 1-18
| Repeatable
for credit
Instructors:
Chen, J. (PI)
;
Cimprich, K. (PI)
;
Elias, J. (PI)
;
Ferrell, J. (PI)
;
Jarosz, D. (PI)
;
Meyer, T. (PI)
;
Mochly-Rosen, D. (PI)
;
Teruel, M. (PI)
;
Wandless, T. (PI)
;
Wysocka, J. (PI)
CSB 201: Chemical and Systems Biology Bootcamp
In this "boot camp" students perform hands-on original research in small groups, combining chemical biology systems-level approaches to investigate current biological problems. This year's course will investigate the function and regulation of uncharacterized genes. Students will acquire conceptual and methodological training in a wide range of modern techniques, including "omics" approaches, fluorescence microscopy, genome editing, computational approaches, and quantitative data analysis.
Terms: Aut
| Units: 1
CSB 210: Cell Signaling
The molecular mechanisms through which cells receive and respond to external signals. Emphasis is on principles of cell signaling, the systems-level properties of signal transduction modules, and experimental strategies through which cell signaling pathways are being studied. Prerequisite: working knowledge of biochemistry and genetics.
Terms: Win
| Units: 4
CSB 220: Chemistry of Biological Processes (BIOC 220)
The principles of organic and physical chemistry as applied to biomolecules. The goal is a working knowledge of chemical principles that underlie biological processes, and chemical tools used to study and manipulate biological systems. Current topics may include chemical genetics, activity-based probes, DNA/RNA chemistry and molecular evolution, protein labeling, carbohydrate engineering, fluorescent proteins and sensors, optochemical/optogenetic methods, mass spectrometry, and genome-editing technologies. Prerequisites: organic chemistry and biochemistry, or consent of instructor.
Terms: Spr
| Units: 3
Instructors:
Wandless, T. (PI)
CSB 240A: A Practical Approach to Drug Discovery and Development
Advancing a drug from discovery of a therapeutic target to human trials and commercialization. Topics include: high throughput assay development, compound screening, lead optimization, protecting intellectual property, toxicology testing, regulatory issues, assessment of clinical need, defining the market, conducting clinical trials, project management, and commercialization issues, including approach to licensing and raising capital. Maximum units are available by taking an additional contact hour.
Terms: Win
| Units: 3-4
Instructors:
Grimes, K. (PI)
;
Mochly-Rosen, D. (PI)
CSB 240B: A Practical Approach to Drug Discover and Development
(Continuation of 240A) Advancing a drug from discovery of a therapeutic target to human trials and commercialization. Topics include: high throughput assay development, compound screening, lead optimization, protecting intellectual property, toxicology testing, regulatory issues, assessment of clinical need, defining the market, conducting clinical trials, project management, and commercialization issues, including approach to licensing and raising capital. Maximum units are available by taking an additional contact hour. Prerequisite: 240A.
Terms: Spr
| Units: 3-4
Instructors:
Grimes, K. (PI)
;
Mochly-Rosen, D. (PI)
CSB 242: Drug Discovery and Development Seminar Series
The scientific principles and technologies involved in making the transition from a basic biological observation to the creation of a new drug emphasizing molecular and genetic issues. Prerequisite: biochemistry, chemistry, or bioengineering.
Terms: Aut, Win, Spr, Sum
| Units: 1
| Repeatable
2 times
(up to 2 units total)
Instructors:
Grimes, K. (PI)
;
Mochly-Rosen, D. (PI)
CSB 245: Economics of Biotechnology
Focuses on translation of promising research discovery into marketed drugs and the integration of scientific method, clinical needs assessment, clinical and regulatory strategy, market analysis, economic considerations, and the influence of the healthcare economic ecosystem necessary for successful translation. Explores the economic perspectives of various stakeholders--patients, providers, payers, biotechnology and pharmaceutical companies, FDA, and financial markets--and how they influence drug development.
Terms: Spr
| Units: 2
Instructors:
Grimes, K. (PI)
;
Mochly-Rosen, D. (PI)
CSB 250: The Biology of Chromatin Templated Processes
Topics include mechanisms of DNA replication; gene expressions regulation; DNA damage sensing and DNA repair; chromatin structure and function; and epigenetics and nuclear reprogramming. Prerequisite: working knowledge of molecular biology, biochemistry and genetics, or instructor consent.
Terms: Win
| Units: 3
CSB 270: Research Seminar
Guest speakers and discussion on current research in pharmacology.
Terms: Win
| Units: 1
| Repeatable
for credit
Filter Results: