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1 - 10 of 47 results for: GENE

GENE 104Q: Law and the Biosciences

Preference to sophomores. Focus is on human genetics; also assisted reproduction and neuroscience. Topics include forensic use of DNA, genetic testing, genetic discrimination, eugenics, cloning, pre-implantation genetic diagnosis, neuroscientific methods of lie detection, and genetic or neuroscience enhancement. Student presentations on research paper conclusions.
Terms: not given this year | Units: 3 | UG Reqs: WAY-ER, Writing 2 | Grading: Letter or Credit/No Credit
Instructors: Greely, H. (PI)

GENE 212: Introduction to Biomedical Informatics Research Methodology (BIOE 212, BIOMEDIN 212, CS 272)

Hands-on software building. Student teams conceive, design, specify, implement, evaluate, and report on a software project in the domain of biomedicine. Creating written proposals, peer review, providing status reports, and preparing final reports. Guest lectures from professional biomedical informatics systems builders on issues related to the process of project management. Software engineering basics. Prerequisites: BIOMEDIN 210, 211, 214, 217 or consent of instructor.
Terms: Spr | Units: 3 | Grading: Medical Option (Med-Ltr-CR/NC)
Instructors: Altman, R. (PI)

GENE 214: Representations and Algorithms for Computational Molecular Biology (BIOE 214, BIOMEDIN 214, CS 274)

Topics: introduction to bioinformatics and computational biology, algorithms for alignment of biological sequences and structures, computing with strings, phylogenetic tree construction, hidden Markov models, Gibbs Sampling, basic structural computations on proteins, protein structure prediction, protein threading techniques, homology modeling, molecular dynamics and energy minimization, statistical analysis of 3D biological data, integration of data sources, knowledge representation and controlled terminologies for molecular biology, microarray analysis, machine learning (clustering and classification), and natural language text processing. Prerequisites: programming skills; consent of instructor for 3 units.
Terms: Aut | Units: 3-4 | Grading: Medical Option (Med-Ltr-CR/NC)
Instructors: Altman, R. (PI)

GENE 217: Translational Bioinformatics

(Same as BIOMEDIN 217, CS 275) Analytic, storage, and interpretive methods to optimize the transformation of genetic, genomic, and biological data into diagnostics and therapeutics for medicine. Topics: access and utility of publicly available data sources; types of genome-scale measurements in molecular biology and genomic medicine; analysis of microarray data; analysis of polymorphisms, proteomics, and protein interactions; linking genome-scale data to clinical data and phenotypes; and new questions in biomedicine using bioinformatics. Case studies. Prerequisites: programming ability at the level of CS 106A and familiarity with statistics and biology.
Terms: Win | Units: 4 | Grading: Medical Option (Med-Ltr-CR/NC)
Instructors: Butte, A. (PI)

GENE 245: Statistical and Machine Learning Methods for Genomics (BIO 268, BIOMEDIN 245, CS 373, STATS 345)

Computational algorithms for human genetics research. Topics include: permutation, bootstrap, expectation maximization, hidden Markov model, and Markov chain Monte Carlo. Rationales and techniques illustrated with existing implementations commonly used in population genetics research, disease association studies, and genomics analysis. Prerequisite: GENE 244 or consent of instructor
Terms: Spr | Units: 3 | Grading: Medical Option (Med-Ltr-CR/NC)

GENE 286C: Advanced Genetic Counseling Seminar

Continuation of 286A/B. For genetic counseling students only. Psychosocial issues associated with genetic counseling cases are discussed through presentation of cases that students have seen throughout their training. Professional development topics including: the expanding roles of genetic counselors; billing, reimbursement, and licensing; the role of genetic counseling in the changing healthcare system; the incorporation of genetics into all areas of medicine and public health; and implications of direct-to-consumer genetic testing. Prerequisites: GENE 285 A,B,C and 276.
Terms: Spr | Units: 2 | Grading: Medical Option (Med-Ltr-CR/NC)

GENE 199: Undergraduate Research

Students undertake investigations sponsored by individual faculty members. Prerequisite: consent of instructor.
Terms: Aut, Win, Spr, Sum | Units: 1-18 | Repeatable for credit | Grading: Letter or Credit/No Credit

GENE 202: Human Genetics

Utilizes lectures and small group activities to develop a working knowlege of human genetics as applicable to clinical medicine. Basic principles of inheritance, risk assessment, and population genetics are illustrated using examples drawn from diverse areas of medical genetics practice including prenatal, pediatric, adult and cancer genetics. Practical aspects of molecular and cytogenetic diagnostic methods emphasized. Existing and emerging treatment strategies for single gene disorders are also covered. Prerequisites: biochemistry, basic genetics.
Terms: Aut | Units: 4 | Grading: Medical Option (Med-Ltr-CR/NC)
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