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1 - 10 of 10 results for: BIOS

BIOS 204: Practical Tutorial on the Modeling of Signal Transduction Motifs

Basics of ordinary differential equation modeling of signal transduction motifs, small circuits of regulatory proteins and genes that serve as building blocks of complex regulatory circuits. Morning session covers numerical modeling experiments. Afternoon session explores theory underpinning that day's modeling session. Modeling done using Mathematica, Standard Edition provided to enrolled students.
Terms: Spr | Units: 3 | Grading: Medical Satisfactory/No Credit
Instructors: Ferrell, J. (PI)

BIOS 205: Introduction to R

Autumn quarter enrollment limited to ADVANCE students; instructor consent required for enrollment. Topics include: basics of R (widely used, open-source programming and data analysis environment) programming language and data structures, reading/writing files, graphics tools for figure generation, basic statistical and regression operations, survey of relevant R library packages. Interactive format combining lectures and computer lab. For course and enrollment information, see http://bios205.stanford.edu.
Terms: Aut, Win, Spr | Units: 1 | Grading: Medical Satisfactory/No Credit
Instructors: Bagley, S. (PI)

BIOS 227: Mass Spectrometry and Proteomics: Opening the Black Box

Focus on designing and analyzing effective proteomics experiments using mass spectrometry and critically evaluating published mass spectrometry-based studies and datasets. Introduces students to the instrumentation, experimental strategies, and computational methods used for identifying and quantifying proteins and protein post-translational modifications using mass spectrometry. Topics include comparative evaluation of mass spectrometer instrument configurations, tandem mass spectrum interpretation, relative and absolute quantitation, and proteome-scale data set analysis. Laboratory time will focus on sample preparation methods, real-time data acquisition, and data analysis software and techniques.
Terms: Spr | Units: 2 | Grading: Satisfactory/No Credit

BIOS 235: Metabolism and Metabolic Ecology: Microbes, Gut and Cancer

Preference to graduate students. Focuses on modern aspects of metabolism and metabolic biochemistry as it affects fitness and ecology of cells and organisms on a systems level. Students obtain a broad understanding of the governing principles and logic of metabolic pathways and their networks as well as an intuition of metabolism in context of natural selection and fitness acting on the cell or host. Emphasis is primarily on microorganisms and their habitats in nature and the human gut, but topics also include metabolism of cancer cells and of engineered microbes.
Terms: Spr | Units: 2 | Grading: Medical Option (Med-Ltr-CR/NC)
Instructors: Spormann, A. (PI)

BIOS 236: Developmental Biology in the Ocean: Comparative Embryology and Larval Development

Three-week course at Hopkins Marine Station. Focuses on the embryology and larval development of a broad range of marine invertebrate phyla. The goal of the course is to give students an appreciation of the range of developmental strategies and larval forms in the ocean and why this is critical for constructing hypotheses of EvoDevo and animal evolution. Includes observation and documentation of the development of embryos and larvae by scientific illustration and photo/video microscopy. Pre-requisite: Developmental Biology coursework and instructor consent.
Terms: Spr | Units: 4 | Grading: Medical Option (Med-Ltr-CR/NC)
Instructors: Lowe, C. (PI)

BIOS 253: Discovery and Innovation in Emerging Viral Infections

An interdisciplinary mini course focused on challenges posed by emerging viruses and innovative efforts to overcome them. Modules include epidemiology and ecology of emerging viral infections, such as Ebola, dengue, and Zika, discovery of new emerging viruses, development and application of molecular assays for the diagnosis and management of emerging viral infections, bioinformatics and genetic approaches for antiviral target discovery, and novel therapeutic approaches for combating emerging viruses. It is intended for graduate students and postdoctoral fellows interested in emerging viral infections. Advanced undergraduates are also welcome. Prerequisite: background in molecular biology.
Terms: Win | Units: 1 | Grading: Medical Satisfactory/No Credit
Instructors: Einav, S. (PI)

BIOS 254: DataLucence::Images

Increasingly, research in the biosciences involves data in digital formats and scientists spend a significant fraction of their time building and using software to harvest insight from digital data. A central goal of this course is to expose students to concepts adopted from computer science and data science regarding data management, data curation, and analytical workflows for analyzing digital data. We will focus on digital images since this image type is used in diverse sub-fields in the biosciences. The course will consist of a two-day workshop/lab¿SoftwareCarpentry¿and six DataLucence::Images+Hackathon class meetings.
Terms: Spr | Units: 2 | Grading: Medical Option (Med-Ltr-CR/NC)
Instructors: Goodman, M. (PI)

BIOS 257: HIV: The virus, the disease, the research

Medical students, graduate students in biological sciences, undergraduate students with strong biological background. Topics: Immunopathogenesis, immune deficits, opportunistic infections including TB, and malignancies; Genomics viral genetic analyses that have traced the origin of HIV-1 and HIV-2 to primates, dated the spread of infection in humans, and characterized theevolution of virus within infected individuals; Antiretroviral drug development identification of drug targets, structure-based drug design, overcoming drug resistance; Challenges of vaccine development; Public health strategies
Terms: Spr | Units: 1 | Grading: Medical Satisfactory/No Credit
Instructors: Shafer, R. (PI)

BIOS 262: Learning to Fly: Drosophila Research Methods

This week-long course will be an overview of the fly as a model system, and the tools available to fly researchers. It will cover topics like history, anatomy, development, online databases, genetic toolkits, genome editing techniques, and stem cell, immunology, and neural research methods. Lectures will be given by experts in the field, who will also be encouraged to discuss the advantages and disadvantages of the fly, as well as how this model system differs from vertebrate systems. We will also provide an optional 2-hour lab that will expose students who have little fly experience to basic fly techniques.
Terms: Spr | Units: 1 | Grading: Medical Option (Med-Ltr-CR/NC)

BIOS 263: Applied Grant-Writing Skills for Fellowships

Graduate students in the Biosciences PhD Programs develop a fellowship proposal (e.g. NIH F31) focusing on required documents: 1-page specific aims as well as research and career development plans. Students establish a writing practice and learn fundamental grant writing skills through guided exercises, including in-class review and focused faculty feedback.
Terms: Spr | Units: 2 | Repeatable for credit | Grading: Medical Satisfactory/No Credit
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