BIOE 41: Physical Biology of Macromolecules
Principles of statistical physics, thermodynamics, and kinetics with applications to molecular biology. Topics include entropy, temperature, chemical forces, enzyme kinetics, free energy and its uses, self assembly, cooperative transitions in macromolecules, molecular machines, feedback, and accurate replication. Prerequisites:
MATH 41, 42;
CHEM 31A, B (or 31X); strongly recommended:
PHYSICS 41,
CME 100 or
MATH 51, and
CME 106; or instructor approval.
Terms: Win
| Units: 4
| UG Reqs: WAY-AQR, WAY-SMA
BIOE 244: Advanced Frameworks and Approaches for Engineering Integrated Genetic Systems
Concepts and techniques for the design and implementation of engineered genetic systems. Topics covered include the quantitative exploration of tools that support (a) molecular component engineering, (b) abstraction and composition of functional genetic devices, (c) use of control and dynamical systems theory in device and systems design, (d) treatment of molecular "noise", (e) integration of DNA-encoded programs within cellular chassis, (f) designing for evolution, and (g) the use of standards in measurement, genetic layout architecture, and data exchange. Prerequisites:
CME104,
CME106,
CHEM 33,
BIO41,
BIO42,
BIOE41,
BIOE42, and
BIOE44 (or equivalents), or permission of the instructors.
Terms: Spr
| Units: 4
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