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BIO 213: Biology of Viruses

Principles of virus growth, genetics, architecture, and assembly. The relation of temperate viruses and other episomes to the host cell. Prerequisite: Biology core. Recommended: 118.
Instructors: Campbell, A. (PI)

BIO 214: Advanced Cell Biology (BIOC 224, MCP 221)

For Ph.D. students. Current research on cell structure, function, and dynamics. Topics include complex cell phenomena such as cell division, apoptosis, compartmentalization, transport and trafficking, motility and adhesion, differentiation, and multicellularity. Current papers from the primary literature. Prerequisite for advanced undergraduates: BIO 129A,B, and consent of instructor.
Terms: Win | Units: 2-5

BIO 217: Neuronal Biophysics

Biophysical descriptions and mechanisms of passive and excitable membranes, ion channels and pumps, action potential propagation, and synaptic transmission. Introduction to dynamics of single neurons and neuronal networks. Emphasis is on the experimental basis for modern research applications. Interdisciplinary aspects of biology and physics. Literature, problem sets, and student presentations. Prerequisites: undergraduate physics, calculus, and biology.
Terms: Win | Units: 4

BIO 218: Genetic Analysis of Biological Processes (BIO 118)

Genetic principles and their experimental applications. Emphasis is on the identification and use of mutations to study cellular function. Prerequisite: Biology core.
Terms: Spr | Units: 5
Instructors: Baker, J. (PI)

BIO 223: Stochastic and Nonlinear Dynamics (APPPHYS 223)

Theoretical analysis of dynamical processes: dynamical systems, stochastic processes, and spatiotemporal dynamics. Motivations and applications from biology and physics. Emphasis is on methods including qualitative approaches, asymptotics, and multiple scale analysis. Prerequisites: ordinary and partial differential equations, complex analysis, and probability or statistical physics.
Terms: Spr | Units: 3
Instructors: Fisher, D. (PI)

BIO 230: Molecular and Cellular Immunology

For advanced undergraduate and graduate students. Components of the immune system and mechanisms of immune responses: structure, function, and genetics of antibody molecules; cellular basis of immunity and its regulation; molecular biology and biochemistry of antigen receptors and signaling pathways; genetic control of immunity and disease susceptibility. Emphasis is on key experimental approaches. Prerequisite for undergraduates: Biology or Human Biology core, or consent of instructor.
Terms: Aut | Units: 4

BIO 230A: Molecular and Cellular Immunology Literature Review

Special discussion section for graduate students. Supplement to 230. Corequisite: 230.
Terms: Aut | Units: 1

BIO 232: Advanced Imaging Lab in Biophysics (APPPHYS 232, BIO 132, BIOPHYS 232, MCP 232)

Laboratory and lectures. Advanced microscopy and imaging, emphasizing hands-on experience with state-of-the-art techniques. Students construct and operate working apparatus. Topics include microscope optics, Koehler illumination, contrast-generating mechanisms (bright/dark field, fluorescence, phase contrast, differential interference contrast), and resolution limits. Laboratory topics vary by year, but include single-molecule fluorescence, fluorescence resonance energy transfer, confocal microscopy, two-photon microscopy, and optical trapping. Limited enrollment. Recommended: basic physics, Biology core or equivalent, and consent of instructor.
Terms: Spr | Units: 4

BIO 237: Plant Genetics (BIO 137)

Gene analysis, mutagenesis, transposable elements; developmental genetics of flowering and embryo development; biochemical genetics of plant metabolism; scientific and societal lessons from transgenic plants. Prerequisite: Biology core or consent of instructor.
Terms: Spr | Units: 3-4
Instructors: Walbot, V. (PI)

BIO 243: Evolution (BIO 143)

The basic facts and principles of the evolution of all life. The logic of and evidence for the correctness of Darwin's argument for evolution by natural selection. How Mendelian genetics was integrated into evolutionary thinking. The integration of physiological and ecological perspectives into the study of evolutionary adaptation within species. Species formation and evolutionary divergence among species. Patterns of evolution over long time scales.
Terms: Aut | Units: 3
Instructors: Watt, W. (PI)
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