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11 - 20 of 39 results for: BIOE ; Currently searching spring courses. You can expand your search to include all quarters

BIOE 199A: Inventing Synthetic Biosystems

Biology as a technology is burgeoning, leading to diverse cultural, economic, geopolitical, and natural outcomes. Students in this course will learn to step back from the overwhelming immediacy of biotechnology's application and to instead adopt a culture of play that enables qualitative expansion of ideas and possibilities. So enriched students will also learn to map ideas onto a future constrained by practical realities and market dynamics. Active in-class participation and a team-based final project are required.
Terms: Spr | Units: 1-2 | Repeatable 2 times (up to 4 units total)

BIOE 201C: Diagnostic Devices Lab (BIOE 301C)

This course exposes students to the engineering principles and clinical application of medical devices through lectures and hands-on labs, performed in teams of two. Teams take measurements with these devices and fit their data to theory presented in the lecture. Devices covered include X-ray, CT, MRI, EEG, ECG, Ultrasound and BMI (Brain-machine interface). Prerequisites: BIOE 103 or BIOE 300B.
Terms: Spr | Units: 2-5

BIOE 204: Genetic and Epigenetic Engineering

This course will cover the fundamental principles of genetic and epigenetic engineering, starting from the key biological discoveries to the current technological applications. We will be dissecting classic literature, formulating our own scientific questions, and designing experiments or calculations to test our answers. Topics include: gene editing using transposases, integrases and nucleases, gene regulation with a focus on transcriptional control, chromatin-mediated epigenetic regulation, and epigenetic editing.
Terms: Spr | Units: 2

BIOE 212: Introduction to Biomedical Data Science Research Methodology (BIOMEDIN 212, CS 272, GENE 212)

Capstone Biomedical Data Science experience. Hands-on software building. Student teams conceive, design, specify, implement, evaluate, and report on a software project in the domain of biomedicine. Creating written proposals, peer review, providing status reports, and preparing final reports. Issues related to research reproducibility. Guest lectures from professional biomedical informatics systems builders on issues related to the process of project management. Software engineering basics. Because the team projects start in the first week of class, attendance that week is strongly recommended. Prerequisites: BIOMEDIN 210 or 214 or 215 or 217 or 260. Preference to BMI graduate students. Consent of instructor required.NOTE: For students in the Department of Biomedical Data Science Program, this core course MUST be taken as a letter grade only.
Terms: Spr | Units: 3-5

BIOE 217: Translational Bioinformatics (BIOMEDIN 217, CS 275, GENE 217)

Analytic and interpretive methods to optimize the transformation of genetic, genomic, and biological data into diagnostics and therapeutics for medicine. Topics: access and utility of publicly available data sources; types of genome-scale measurements in molecular biology and genomic medicine; linking genome-scale data to clinical data and phenotypes; and new questions in biomedicine using bioinformatics. Case studies. Prerequisites: programming ability at the level of CS 106A and familiarity with statistics and biology.
Terms: Spr | Units: 3-4

BIOE 230: Measurements, Statistics, and Probability

A combined lecture and laboratory course providing an introductory treatment of probability theory, including random variables/vectors, probability distributions, calculations of expectations and variances, limit theorems, hypothesis testing, model fitting (frequentist and Bayesian perspectives), assessing goodness of fit, and quantifying uncertainty. Practical applications include linear regression, logistical regression, and their applications to biomedical data.
Terms: Spr | Units: 4

BIOE 231: Protein Engineering (BIOE 331)

The design and engineering of biomolecules with biotechnological applications, with special emphasis on binders and enzymes. Overview of protein structure, function, biophysical analysis, computational design, rational engineering, and directed evolution. Discussions of examples with conceptual or medical significance. Prerequisite: Chem 141, BioE 241, or similar upon instructor approval
Terms: Spr | Units: 3
Instructors: Lin, M. (PI)

BIOE 232: Advanced Imaging Lab in Biophysics (APPPHYS 232, BIO 132, BIO 232, BIOPHYS 232, GENE 232)

Laboratory and lectures. Advanced microscopy and imaging, emphasizing hands-on experience with state-of-the-art techniques. Students construct and operate working apparatus. Topics include microscope optics, Koehler illumination, contrast-generating mechanisms (bright/dark field, fluorescence, phase contrast, differential interference contrast), and resolution limits. Laboratory topics vary by year, but include single-molecule fluorescence, fluorescence resonance energy transfer, confocal microscopy, two-photon microscopy, microendoscopy, and optical trapping. Limited enrollment. Recommended: basic physics, basic cell biology, and consent of instructor.
Terms: Spr | Units: 4

BIOE 256: Technology Assessment and Regulation of Medical Devices (MS&E 256)

Regulatory approval and reimbursement for new health technologies are critical success factors for product commercialization. This course explores the regulatory and payer environment in the U.S. and abroad, as well as common methods of health technology assessment. Students will learn frameworks to identify factors relevant to the adoption of new health technologies, and the management of those factors in the design and development phases of bringing a product to market through case studies, guest speakers from government (FDA) and industry, and a course project.
Terms: Spr | Units: 3

BIOE 260: Tissue Engineering (ORTHO 260)

Principles of tissue engineering and design strategies for practical applications for tissue repair. Topics include tissue morphogenesis, stem cells, biomaterials, controlled drug and gene delivery, and paper discussions. Students will learn skills for lab research through interactive lectures, paper discussions and research proposal development. Students work in small teams to work on develop research proposal for authentic tissue engineering problems. Lab sessions will teach techniques for culturing cells in 3D, as well as fabricating and characterizing hydrogels as 3D cell niche.
Terms: Spr | Units: 4
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