CSB 199: Undergraduate Research
Students undertake investigations sponsored by individual faculty members. Prerequisite: consent of instructor.
Terms: Aut, Win, Spr, Sum
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Units: 1-18
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Repeatable for credit
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Grading: Satisfactory/No Credit
CSB 222: Imaging: Biological Light Microscopy (BIO 152, MCP 222)
This intensive laboratory and discussion course will provide participants with the theoretical and practical knowledge to utilize emerging imaging technologies based on light microscopy. Topics include microscope optics, resolution limits, Köhler illumination, confocal fluorescence, two-photon, TIRF, FRET, photobleaching, super-resolution (SIM, STED, STORM/PALM), tissue clearing/CLARITY/light-sheet microscopy, and live-cell imaging. Applications include using fluorescent probes to analyze subcellular localization and live cell-translocation dynamics. We will be using a ¿flipped¿ classroom for the course in that students will watch iBiology lectures before class, and class time will be used for engaging in extensive discussion. Lab portion involves extensive in-class use of microscopes in the CSIF and NMS core microscopy facilities. Monday/Wednesday 1:30-2:50PM, Friday 1:30-4:30PM for 6 weeks (Apr. 2 - May 9), 3 units
Terms: Spr
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Units: 3
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Grading: Medical Option (Med-Ltr-CR/NC)
Instructors:
Teruel, M. (PI)
CSB 224: Chemical and Systems Biology Pizza Talks
Required of and limited to all graduate students and postdoctoral scholar in the Department of Chemical and Systems Biology. Students and postdocs are required to give in-depth presentations about their current projects within the academic year.
Terms: Aut, Win, Spr, Sum
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Units: 1
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Repeatable for credit
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Grading: Medical Option (Med-Ltr-CR/NC)
Instructors:
Chen, J. (PI)
CSB 242: Drug Discovery and Development Seminar Series
The scientific principles and technologies involved in making the transition from a basic biological observation to the creation of a new drug emphasizing molecular and genetic issues. Prerequisite: biochemistry, chemistry, or bioengineering.
Terms: Aut, Win, Spr, Sum
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Units: 1
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Repeatable for credit
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Grading: Medical Satisfactory/No Credit
Instructors:
Grimes, K. (PI)
;
Mochly-Rosen, D. (PI)
CSB 245: Economics of Biotechnology
Focuses on translation of promising research discovery into marketed drugs and the integration of scientific method, clinical needs assessment, clinical and regulatory strategy, market analysis, economic considerations, and the influence of the healthcare economic ecosystem necessary for successful translation. Explores the economic perspectives of various stakeholders--patients, providers, payers, biotechnology and pharmaceutical companies, FDA, and financial markets--and how they influence drug development.
Terms: Spr
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Units: 2
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Grading: Medical Option (Med-Ltr-CR/NC)
Instructors:
Grimes, K. (PI)
CSB 250: The Biology of Chromatin Templated Processes
Topics include mechanisms of DNA replication; gene expressions regulation; DNA damage sensing and DNA repair; chromatin structure and function; and epigenetics and nuclear reprogramming. Prerequisite: working knowledge of molecular biology, biochemistry and genetics, or instructor consent.
Terms: not given this year
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Units: 3
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Grading: Medical Option (Med-Ltr-CR/NC)
CSB 260: Concepts and Applications in Chemical Biology
Current topics include chemical genetics, activity-based probes, inducible protein degradation, DNA/RNA chemistry and molecular evolution, protein labeling, carbohydrate engineering, fluorescent proteins and sensors, optochemical/optogenetic methods, mass spectrometry, and genome-editing technologies.
Terms: Spr
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Units: 3
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Grading: Medical Option (Med-Ltr-CR/NC)
Instructors:
Chen, J. (PI)
CSB 270: Research Seminar
Guest speakers and discussion on current research in pharmacology.
Terms: Aut, Win, Spr
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Units: 1
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Repeatable for credit
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Grading: Medical Satisfactory/No Credit
Instructors:
Jarosz, D. (PI)
;
Teruel, M. (PI)
CSB 290: Curricular Practical Training
CPT Course required for international students completing degree requirements.
Terms: Aut, Win, Spr
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Units: 1
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Grading: Medical Satisfactory/No Credit
CSB 299: Directed Reading in Chemical and Systems Biology
Prerequisite: consent of instructor.
Terms: Aut, Win, Spr, Sum
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Units: 1-18
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Repeatable for credit
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Grading: Medical Satisfactory/No Credit
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