BIOS 209: Practical Protein NMR Structure Determination
Work toward solving a high-resolution 3D structure from unprocessed NMR data acquired on a small well-characterized protein. Short lectures followed by hands-on computer exercises demonstrate best practices for data processing, spectra interpretation, and structure calculation with attention to troubleshooting and validation methods. Students should be familiar with fundamental concepts of protein structure and NMR spectroscopy and comfortable with the command-line environment. Prerequisite:
SBIO242/
BIOPHYS 242 strongly recommended, but not required.
Last offered: Winter 2014
SBIO 242: Methods in Molecular Biophysics (BIOPHYS 242)
Experimental methods in molecular biophysics from theoretical and practical standpoints. Emphasis is on X-ray diffraction, nuclear magnetic resonance, and fluorescence spectcroscopy. Prerequisite: physical chemistry or consent of instructor.
Terms: Win
| Units: 3
Instructors:
Puglisi, J. (PI)
;
Weis, W. (PI)
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