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BIOE 80: Introduction to Bioengineering (ENGR 80)

Overview of biological engineering focused on engineering analysis and design of biological processes. Topics include overall material and energy balances, rates of biochemical reactions and processes, genetic programming of biological systems, links between information and function, and technologies to probe and manipulate biological systems. Applications of these concepts to areas of current technological importance, including biotechnology, biosynthesis, molecular/cellular therapeutics, and personalized medicine and gene therapy.
Terms: Spr | Units: 3 | UG Reqs: WAY-FR, GER:DB-EngrAppSci
Instructors: Smolke, C. (PI)

BIOE 10N: Form and Function of Animal Skeletons (ME 10N)

Preference to freshmen. The biomechanics and mechanobiology of the musculoskeletal system in human beings and other vertebrates on the level of the whole organism, organ systems, tissues, and cell biology. Field trips to labs.
| UG Reqs: GER:DB-EngrAppSci

BIOE 144: Lectures and Dialogue on Synthetic Biology

New foundational tools that are making biology easier to engineer. Topics include DNA synthesis, RNA, protein, and cellular engineering, programmed pattern formation, standardization, and abstraction. Current and future applications of biotechnology. Social issues such as ethics, safety, security, and ownership, sharing, and innovation frameworks. All majors welcome; optional weekly background tutorial.
Terms: Win | Units: 3

BIOE 191: Bioengineering Problems and Experimental Investigation

Directed study and research for undergraduates on a subject of mutual interest to student and instructor. Prerequisites: consent of instructor and adviser. (Staff)
Terms: Aut, Win, Spr, Sum | Units: 1-5 | Repeatable for credit

BIOE 212: Introduction to Biomedical Informatics Research Methodology (BIOMEDIN 212, CS 272, GENE 212)

Terms: Aut | Units: 3

BIOE 214: Representations and Algorithms for Computational Molecular Biology (BIOMEDIN 214, CS 274, GENE 214)

Topics: introduction to bioinformatics and computational biology, algorithms for alignment of biological sequences and structures, computing with strings, phylogenetic tree construction, hidden Markov models, Gibbs Sampling, basic structural computations on proteins, protein structure prediction, protein threading techniques, homology modeling, molecular dynamics and energy minimization, statistical analysis of 3D biological data, integration of data sources, knowledge representation and controlled terminologies for molecular biology, microarray analysis, machine learning (clustering and classification), and natural language text processing. Prerequisites: programming skills; consent of instructor for 3 units.
Terms: Spr | Units: 3-4

BIOE 220: Imaging Anatomy (RAD 220)

The physics of medical imaging and human anatomy through medical images. Emphasis is on normal anatomy, contrast mechanisms, and the relative strengths of each imaging modality. Labs reinforce imaging techniques and anatomy. Prerequisites: basic biology, physics.
Terms: Win | Units: 3

BIOE 222A: Multimodality Molecular Imaging in Living Subjects (RAD 222A)

Focuses on instruments and chemistries for imaging of cellular and molecular processes in vivo. Basics of instrumentation physics, chemistry of molecular imaging probes, and an introduction to preclinical and clinical molecular imaging modalities.
Terms: Aut | Units: 4

BIOE 222B: Chemistry of Molecular Probes for Imaging in Living Subjects (RAD 222B)

Focuses on molecular probes that target specific disease mechanisms. The ideal characteristics of molecular probes; how to optimize their design for use as effective imaging reagents that target specific steps in biological pathways and reveal the nature of disease through noninvasive assays.
Terms: Win | Units: 4

BIOE 222C: Topics in Multimodality Imaging in Living Subjects (RAD 222C)

Focuses on emerging chemistries and instruments that address unmet needs for improved diagnosis and disease management in cancer, neurological disease, cardiovascular medicine and musculoskeletal disorders. Objective is to identify problems or controversies in the field, and to resolve them through understanding the relevant primary literature.
Terms: Spr | Units: 4
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