printer friendly pageBIOS 241: Dissecting algorithms for RNA Sequencing
Class focuses on a few popular and commonly used algorithms for RNA-Seq analysis. The course dissects the algorithmic assumptions, statistical methods they use to test hypotheses about RNA expression and evaluates properties such as robustness, sensitivity and specificity, highlighting some large "blind spots" in many algorithms.
Last offered: Winter 2015
BIOS 242: Writing Compelling Fellowships and Career Development Awards
An overview of principles and fundamentals for writing competitive fellowships (e.g. NIH F31, F32) and career development awards (e.g. NIH K Awards). Topics include: developing specific aims and career development plans; using the review criteria to inform writing; timelines and resources. Participants develop proposals through guided exercises with an emphasis on in-class peer review and focused faculty feedback.
Terms: Aut
| Units: 2
Instructors:
Botham, C. (PI)
;
Talbot, W. (PI)
BIOS 243: Grant Writing Academy Mini Course: Specific Aims
Concise overview of the fundamentals for writing competitive NIH Kirschtein NRSA fellowships (F31, F32) and K Awards. Topics include developing specific aims; outlining research and career development plans; and using the review criteria to inform writing. Participants develop their one-page NIH-Specific Aims document with an emphasis on in-class peer review and protected daily proposal writing. Students enroll for units in one small-group section, and also attend two mandatory lectures as noted in class schedule.
Last offered: Summer 2016
BIOS 244: Computer Applications in Pharmaceutical Research and Development
After a brief introduction to drug discovery and development process in pharmaceutical industry, we discuss integrative computational approaches to drug discovery, development, and marketing. Illustrative case studies and examples explain how applications are used at various stages, including bioinformatics, data mining, high-throughput screening, predicting human response to drugs, and adverse drug event monitoring.
Last offered: Spring 2016
BIOS 245: The Immune Response to Infectious Diseases
Focuses on the immune defenses that the human body uses to prevent and control infectious diseases. Covers both innate and adaptive immune defenses against bacterial, fungal, and viral pathogens will be covered. This course is targeted primarily at graduate students and postdocs whose primary focus is not in immunology, but whose research and interests intersect with the host response to infectious diseases. Motivated undergraduates may also participate.
Last offered: Winter 2016
BIOS 246: Introduction to Meta-Analysis
Meta-analysis is the quantitative synthesis and analysis of a collection of independent studies. It provides a more objective and powerful way of summarizing evidence across studies than descriptive reviews. The importance and utility of this quantitative method for answering new questions and synthesizing existing results in different fields of scientific research is demonstrated by the dramatic increase in the number of studies using meta-analysis in the last ten years. Focuses on the basics of meta-analysis. The emphasis of the course is both on the conceptual understanding and practical use of this method, as applied to biological questions.
Last offered: Spring 2016
BIOS 247: Neuro-Cellular Core
Focus on fundamental aspects of cellular neurophysiology. Topics include: electrophysiological properties of neurons; synaptic structure and function; synaptic plasticity; didactic lecture component and student-led discussion of classical papers. Students use the simulation program Neuron.
BIOS 248: Scientific Computing for Ecologists, Biologists and Environmental Scientists
One-week intensive course is specifically dedicated to graduate students and postdocs in Biology and Environmental Science eager to be introduced to, and get proficient in, scientific computing. Focus is on acquiring the necessary skills to boost their productivity by learning state-of-the-art and cutting-edge techniques to retrieve and process big data. Course introduces Unix/Linux, R, ggplot2 graphic package, regular expressions and version control, dynamic reporting generation through hands-on and interactive learning opportunities both during lectures and in extensive lab sessions based on real world case studies extracted from published papers.
Last offered: Autumn 2015
BIOS 249: Interactive Microbiology
Focus is on phototactic behavior of single celled organisms and the biophysical principles of feedback control and hydrodynamics underlying it. Enables real biology experimentation in the cloud, and is ultimately intended to illustrate and teach the scientific method (free exploration, hypothesis formation, measurement, data analysis, modeling, conclusions).
Last offered: Winter 2016
BIOS 250: Interdisciplinary Drug Discovery
Focuses on decision making in science, with particular attention to skills for identifying when to solicit interdisciplinary input, and how to guide such discussions to productive endpoints. Uses case studies based on Novartis projects to teach ways to leverage interdisciplinary knowledge, effectively communicate across disciplines, and drive teams to decision points. Two-day workshop presented by Novartis scientists who lead participants through these real life examples of interactive teams within pharma solving problems through collaborative decision making. Participants develop collaborative decision making skills highlighted through group exercises.
Terms: Aut
| Units: 1
Instructors:
Mayes, T. (PI)
;
Talbot, W. (PI)
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