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BIO 199: Advanced Research Laboratory in Experimental Biology

Individual research taken by arrangement with in-department instructors. See http://biohonors.stanford.edu for information on research sponsors, units, and credit for summer research. May be repeated for credit.
Terms: Aut, Win, Spr, Sum | Units: 1-15 | Repeatable 15 times (up to 60 units total)

BIO 199X: Out-of-Department Advanced Research Laboratory in Experimental Biology

Individual research by arrangement with out-of-department instructors. Credit for 199X is restricted to declared Biology majors and requires department approval. See http://biohonors.stanford.edu for information on research sponsors, units, petitions, deadlines, credit for summer research, and out-of-Stanford research. May be repeated for credit.
Terms: Aut, Win, Spr, Sum | Units: 1-15 | Repeatable 15 times (up to 60 units total)
Instructors: Adler, J. (PI) ; Agras, W. (PI) ; Altman, R. (PI) ; Andriacchi, T. (PI) ; Ariagno, R. (PI) ; Arrigo, K. (PI) ; Artandi, S. (PI) ; Arvin, A. (PI) ; Axelrod, J. (PI) ; Baker, J. (PI) ; Barr, D. (PI) ; Barres, B. (PI) ; Barsh, G. (PI) ; Barton, K. (PI) ; Bass, D. (PI) ; Batzoglou, S. (PI) ; Beachy, P. (PI) ; Bergmann, D. (PI) ; Bernstein, D. (PI) ; Bhalla, V. (PI) ; Blaschke, T. (PI) ; Blau, H. (PI) ; Block, B. (PI) ; Block, S. (PI) ; Boggs, C. (PI) ; Bogyo, M. (PI) ; Boothroyd, J. (PI) ; Bouley, D. (PI) ; Boxer, L. (PI) ; Boxer, S. (PI) ; Briggs, W. (PI) ; Brown, J. (PI) ; Brown, P. (PI) ; Brundage, S. (PI) ; Brunet, A. (PI) ; Brutlag, D. (PI) ; Buckmaster, P. (PI) ; Buckwalter, M. (PI) ; Burkholder, B. (PI) ; Butcher, E. (PI) ; Calos, M. (PI) ; Campbell, A. (PI) ; Cartwright, C. (PI) ; Cavalli-Sforza, L. (PI) ; Chan, P. (PI) ; Chang, H. (PI) ; Chang, K. (PI) ; Chase, R. (PI) ; Chawla, A. (PI) ; Chen, J. (PI) ; Chien, Y. (PI) ; Chu, G. (PI) ; Cimprich, K. (PI) ; Clandinin, T. (PI) ; Clayberger, C. (PI) ; Cleary, M. (PI) ; Cochran, J. (PI) ; Cohen, H. (PI) ; Cohen, S. (PI) ; Collman, J. (PI) ; Conley, F. (PI) ; Constantinou, C. (PI) ; Contag, C. (PI) ; Cooke, J. (PI) ; Cooper, A. (PI) ; Crabtree, G. (PI) ; Criddle, C. (PI) ; Cyert, M. (PI) ; Daily, G. (PI) ; Dalman, R. (PI) ; Darian-Smith, C. (PI) ; Das, R. (PI) ; Davis, M. (PI) ; Davis, R. (PI) ; Deisseroth, K. (PI) ; Dement, W. (PI) ; Denny, M. (PI) ; Dirzo, R. (PI) ; Dolmetsch, R. (PI) ; Doniach, S. (PI) ; Dorfman, L. (PI) ; Dragoo, J. (PI) ; Ehrhardt, D. (PI) ; Ehrlich, P. (PI) ; Eng, L. (PI) ; Engleman, E. (PI) ; Epel, D. (PI) ; Falcon, W. (PI) ; Falkow, S. (PI) ; Fathman, C. (PI) ; Feldman, D. (PI) ; Feldman, M. (PI) ; Felsher, D. (PI) ; Fernald, R. (PI) ; Ferrell, J. (PI) ; Field, C. (PI) ; Fire, A. (PI) ; Ford, J. (PI) ; Fortmann, S. (PI) ; Foung, S. (PI) ; Francke, U. (PI) ; Fraser, H. (PI) ; Fredericson, M. (PI) ; Friedlander, A. (PI) ; Froelicher, V. (PI) ; Frydman, J. (PI) ; Fukami, T. (PI) ; Fuller, M. (PI) ; Furthmayr, H. (PI) ; Galli, S. (PI) ; Garcia, G. (PI) ; Gardner, P. (PI) ; Garner, C. (PI) ; Giaccia, A. (PI) ; Gilly, W. (PI) ; Girod, S. (PI) ; Giudice, L. (PI) ; Glenn, J. (PI) ; Gold, G. (PI) ; Goodman, M. (PI) ; Goodman, S. (PI) ; Gordon, D. (PI) ; Gozani, O. (PI) ; Gray, G. (PI) ; Greenberg, H. (PI) ; Guilleminault, C. (PI) ; Guzman, R. (PI) ; Hadly, E. (PI) ; Hallmayer, J. (PI) ; Hanawalt, P. (PI) ; Haskell, W. (PI) ; Heilshorn, S. (PI) ; Heller, H. (PI) ; Helms, J. (PI) ; Herschlag, D. (PI) ; Herzenberg, L. (PI) ; Hestrin, S. (PI) ; Hodgson, K. (PI) ; Hoffman, A. (PI) ; Hoffman, B. (PI) ; Hogness, D. (PI) ; Hsu, S. (PI) ; Hsueh, A. (PI) ; Huestis, W. (PI) ; Huguenard, J. (PI) ; Jackson, P. (PI) ; Jardetzky, O. (PI) ; Jones, P. (PI) ; Kahn, D. (PI) ; Kaiser, A. (PI) ; Karasek, M. (PI) ; Katzenstein, D. (PI) ; Kay, M. (PI) ; Kendig, J. (PI) ; Khavari, P. (PI) ; Kim, S. (PI) ; Kim, S. (PI) ; King, A. (PI) ; Kingsley, D. (PI) ; Knox, S. (PI) ; Knudsen, E. (PI) ; Knutson, B. (PI) ; Kobilka, B. (PI) ; Koong, A. (PI) ; Kopito, R. (PI) ; Kornberg, A. (PI) ; Kornberg, R. (PI) ; Koseff, J. (PI) ; Kraemer, F. (PI) ; Krams, S. (PI) ; Krasnow, M. (PI) ; Krensky, A. (PI) ; Kuo, C. (PI) ; Lee, P. (PI) ; Lehman, I. (PI) ; Leung, L. (PI) ; Levenston, M. (PI) ; Levy, R. (PI) ; Levy, S. (PI) ; Lewis, D. (PI) ; Lewis, R. (PI) ; Lipsick, J. (PI) ; Litt, I. (PI) ; Long, S. (PI) ; Longaker, M. (PI) ; Lorenz, H. (PI) ; Lowe, A. (PI) ; Lu, B. (PI) ; Luo, L. (PI) ; Lyons, D. (PI) ; MacIver, M. (PI) ; Mackey, S. (PI) ; Madison, D. (PI) ; Maduke, M. (PI) ; Maldonado, Y. (PI) ; Malenka, R. (PI) ; Marcus, R. (PI) ; Marinkovich, M. (PI) ; Marmor, M. (PI) ; Martinez, O. (PI) ; Matheson, G. (PI) ; Matin, A. (PI) ; McConnell, H. (PI) ; McConnell, S. (PI) ; McDevitt, H. (PI) ; McKay, D. (PI) ; McMahan, U. (PI) ; Mellins, E. (PI) ; Menon, V. (PI) ; Merigan, T. (PI) ; Micheli, F. (PI) ; Michie, S. (PI) ; Mignot, E. (PI) ; Miklos, D. (PI) ; Miller, D. (PI) ; Mobley, W. (PI) ; Mocarski, E. (PI) ; Mochly-Rosen, D. (PI) ; Monack, D. (PI) ; Mooney, H. (PI) ; Morris, R. (PI) ; Morrison, A. (PI) ; Morton, J. (PI) ; Mudgett, M. (PI) ; Murphy, G. (PI) ; Myers, B. (PI) ; Myers, R. (PI) ; Nadeau, K. (PI) ; Negrin, R. (PI) ; Nelson, W. (PI) ; Newsome, W. (PI) ; Nishino, S. (PI) ; Nolan, G. (PI) ; Nusse, R. (PI) ; Oro, A. (PI) ; Palmer, T. (PI) ; Palumbi, S. (PI) ; Parham, P. (PI) ; Parker, K. (PI) ; Parnes, J. (PI) ; Parsonnet, J. (PI) ; Patterson, D. (PI) ; Pearl, R. (PI) ; Pecora, R. (PI) ; Peebles, R. (PI) ; Peehl, D. (PI) ; Petrov, D. (PI) ; Pfeffer, S. (PI) ; Pollack, J. (PI) ; Porzig, E. (PI) ; Prince, D. (PI) ; Pringle, J. (PI) ; Puglisi, J. (PI) ; Quertermous, T. (PI) ; Rabinovitch, M. (PI) ; Raffin, T. (PI) ; Rando, T. (PI) ; Rasgon, N. (PI) ; Raymond, J. (PI) ; Reaven, G. (PI) ; Reimer, R. (PI) ; Reiss, A. (PI) ; Relman, D. (PI) ; Robbins, R. (PI) ; Robertson, C. (PI) ; Robinson, B. (PI) ; Robinson, T. (PI) ; Rockson, S. (PI) ; Rosen, G. (PI) ; Rosenberg, N. (PI) ; Roth, R. (PI) ; Rothschild, L. (PI) ; Roughgarden, J. (PI) ; Sage, J. (PI) ; Sapolsky, R. (PI) ; Sarnow, P. (PI) ; Schatzberg, A. (PI) ; Schneider, D. (PI) ; Schneider, S. (PI) ; Schnitzer, M. (PI) ; Schoolnik, G. (PI) ; Schrier, S. (PI) ; Schwarz, T. (PI) ; Scott, M. (PI) ; Shapiro, L. (PI) ; Shen, K. (PI) ; Shochat, S. (PI) ; Shooter, E. (PI) ; Sibley, E. (PI) ; Sikic, B. (PI) ; Silverberg, G. (PI) ; Simon, M. (PI) ; Simoni, R. (PI) ; Singh, U. (PI) ; Skirboll, S. (PI) ; Skotheim, J. (PI) ; Smith, M. (PI) ; Smith, R. (PI) ; Smith, S. (PI) ; Somero, G. (PI) ; Spiegel, D. (PI) ; Spormann, A. (PI) ; Spudich, J. (PI) ; Stamey, T. (PI) ; Stearns, T. (PI) ; Steele, C. (PI) ; Steinberg, G. (PI) ; Steinman, L. (PI) ; Stevens, D. (PI) ; Stevenson, D. (PI) ; Stockdale, F. (PI) ; Strober, S. (PI) ; Stryer, L. (PI) ; Sudhof, T. (PI) ; Sullivan, E. (PI) ; Sun, Z. (PI) ; Sweet-Cordero (PI) ; Ta, C. (PI) ; Talbot, W. (PI) ; Tan, M. (PI) ; Taylor, C. (PI) ; Taylor, C. (PI) ; Teng, N. (PI) ; Theriot, J. (PI) ; Thompson, S. (PI) ; Triadafilopoulos, G. (PI) ; Tsao, P. (PI) ; Tse, V. (PI) ; Tsien, R. (PI) ; Tuljapurkar, S. (PI) ; Utz, P. (PI) ; Vemuri, M. (PI) ; Villeneuve, A. (PI) ; Vitousek, P. (PI) ; Vollrath, D. (PI) ; Walbot, V. (PI) ; Wandless, T. (PI) ; Wang, T. (PI) ; Watt, W. (PI) ; Waymouth, R. (PI) ; Weinberg, K. (PI) ; Whitlock, J. (PI) ; Wine, J. (PI) ; Winograd, C. (PI) ; Wong, A. (PI) ; Wong, D. (PI) ; Wu, J. (PI) ; Wyss-Coray, T. (PI) ; Yang, Y. (PI) ; Yao, M. (PI) ; Zajac, F. (PI) ; Zare, R. (PI) ; Zarins, C. (PI) ; Zehnder, J. (PI) ; Zeitzer, J. (PI) ; Zhao, H. (PI) ; de Lecea, L. (PI)

BIO 20: Introduction to Brain and Behavior (HUMBIO 21)

Evolutionary principles to understand how the brain regulates behavior physiologically, and is also influenced by behavioral interactions. Topics include neuron structure and function, transmission of neural information, anatomy and physiology of sensory and motor systems, regulation of body states, the biological basis of learning and memory, and behavioral abnormalities.
| UG Reqs: GER: DB-NatSci

BIO 200: Advanced Molecular Biology (BIO 104)

Molecular mechanisms that govern the replication, recombination, and expression of eukaryotic genomes. Topics: DNA replication, DNA recombination, gene transcription, RNA splicing, regulation of gene expression, protein synthesis, and protein folding. Prerequisite: Biology core.
Terms: Win | Units: 5

BIO 203: Advanced Genetics (DBIO 203, GENE 203)

For graduate students in Bioscience programs; may be appropriate for graduate students in other programs. The genetic toolbox. Examples of analytic methods, genetic manipulation, genome analysis, and human genetics. Emphasis is on use of genetic tools in dissecting complex biological pathways, developmental processes, and regulatory systems. Faculty-led discussion sections with evaluation of papers. Students with minimal experience in genetics should prepare by working out problems in college level textbooks.
Terms: Aut | Units: 4

BIO 205: DNA Repair and Genomic Stability

Interactions of endogenous and environmental mutagens with cellular DNA. Cellular responses to damaged DNA including molecular mechanisms for DNA repair, translesion DNA synthesis, and genetic recombination. Inducible repair responses and error-prone mechanisms. Human hereditary diseases that predispose to cancer. Relationships of DNA repair to mutagenesis, carcinogenesis, aging, and human genetic disease. Current research literature. Prerequisites: 41 and 118, or consent of instructor.

BIO 207: Life and Death of Proteins

How proteins are made and degraded in the cell. Discussion of primary literature. Case studies follow the evolution of scientific ideas, and evaluate how different experimental approaches contribute to our understanding of a biological problem. Emphasis on multidisciplinary approaches. Topics: protein folding and assembly, mechanisms of chaperone action, sorting into organelles, misfolding and disease, and the ubiquitin-proteasome pathway. Enrollment limited to 30.
Terms: Win | Units: 3
Instructors: Frydman, J. (PI)

BIO 209A: The Human Genome and Disease (BIO 109A, HUMBIO 158)

The variability of the human genome and the role of genomic information in research, drug discovery, and human health. Concepts and interpretations of genomic markers in medical research and real life applications. Human genomes in diverse populations. Original contributions from thought leaders in academia and industry and interaction between students and guest lecturers.
Terms: Win | Units: 3
Instructors: Heller, R. (PI)

BIO 209B: The Human Genome and Disease: Genetic Diversity and Personalized Medicine (BIO 109B)

Continuation of 109A/209A. Genetic drift: the path of human predecessors out of Africa to Europe and then either through Asia to Australia or through northern Russia to Alaska down to the W. Coast of the Americas. Support for this idea through the histocompatibility genes and genetic sequences that predispose people to diseases. Guest lectures from academia and pharmaceutical companies. Prerequisite: Biology or Human Biology core.
Terms: Spr | Units: 3
Instructors: Heller, R. (PI)

BIO 212: Human Physiology (BIO 112, HUMBIO 133)

The functioning of organ systems emphasizing mechanisms of control and regulation. Topics: structure and function of endocrine and central nervous systems, cardiovascular physiology, respiration, salt and water balance, exercise, and gastrointestinal physiology. Prerequisite: Biology or Human Biology core.
Terms: Win | Units: 4
Instructors: Garza, D. (PI)
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