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1 - 10 of 23 results for: CSB

CSB 199: Undergraduate Research

Students undertake investigations sponsored by individual faculty members. Prerequisite: consent of instructor.
Terms: Aut, Win, Spr, Sum | Units: 1-18 | Repeatable for credit | Grading: Satisfactory/No Credit

CSB 210: Cell Signaling

The molecular mechanisms through which cells receive and respond to external signals. Emphasis is on principles of cell signaling, the systems-level properties of signal transduction modules, and experimental strategies through which cell signaling pathways are being studied. Prerequisite: working knowledge of biochemistry and genetics.
Terms: Win | Units: 4 | Grading: Medical Option (Med-Ltr-CR/NC)
Instructors: Meyer, T. (PI)

CSB 220: Chemistry of Biological Processes

The principles of organic and physical chemistry applied to biomolecules. The goal is a working knowledge of chemical principles that underlie biological processes. Chemical tools and techniques used to study and manipulate biological systems may be used to illustrate these principles. Prerequisites: organic chemistry and biochemistry, or consent of instructor.
Terms: Spr | Units: 3 | Grading: Medical Option (Med-Ltr-CR/NC)
Instructors: Wandless, T. (PI)

CSB 222: Imaging: Biological Light Microscopy (BIO 152, MCP 222)

Biological light microscopy: from theory to practice. This intensive laboratory and lecture course will provide participants with the theoretical and practical knowledge to utilize emerging imaging technologies. Students will learn the principles of light microscopy, as well as use of different types of cameras, laser scanning systems, functional fluorophores, probe delivery techniques. Topics include microscope optics, resolution limits, Koehler illumination, confocal fluorescence, two-photon, TIRF, FRET, photobleaching, super-resolution (SIM, STED, STORM/PALM), and live-cell imaging and cell tracking approaches. Discussion of physical principles; involves partial assembly and extensive use of lab instruments. Lab. Prerequisites: some college physics.
Terms: Spr | Units: 3 | Grading: Medical Option (Med-Ltr-CR/NC)
Instructors: Teruel, M. (PI)

CSB 224: Chemical and Systems Biology Pizza Talks

Required of and limited to all graduate students and postdoctoral scholar in the Department of Chemical and Systems Biology. Students and postdocs are required to give in-depth presentations about their current projects within the academic year.
Terms: Aut, Win, Spr, Sum | Units: 1 | Repeatable for credit | Grading: Medical Option (Med-Ltr-CR/NC)

CSB 240A: A Practical Approach to Drug Discovery and Development

Advancing a drug from discovery of a therapeutic target to human trials and commercialization. Topics include: high throughput assay development, compound screening, lead optimization, protecting intellectual property, toxicology testing, regulatory issues, assessment of clinical need, defining the market, conducting clinical trials, project management, and commercialization issues, including approach to licensing and raising capital. Maximum units are available by taking an additional contact hour.
Terms: Win | Units: 3-4 | Grading: Medical Option (Med-Ltr-CR/NC)

CSB 240B: A Practical Approach to Drug Discover and Development

(Continuation of 240A) Advancing a drug from discovery of a therapeutic target to human trials and commercialization. Topics include: high throughput assay development, compound screening, lead optimization, protecting intellectual property, toxicology testing, regulatory issues, assessment of clinical need, defining the market, conducting clinical trials, project management, and commercialization issues, including approach to licensing and raising capital. Maximum units are available by taking an additional contact hour. Prerequisite: 240A.
Terms: Spr | Units: 3-4 | Grading: Medical Option (Med-Ltr-CR/NC)

CSB 242: Drug Discovery and Development Seminar Series

The scientific principles and technologies involved in making the transition from a basic biological observation to the creation of a new drug emphasizing molecular and genetic issues. Prerequisite: biochemistry, chemistry, or bioengineering.
Terms: Aut, Win, Spr, Sum | Units: 1 | Repeatable for credit | Grading: Medical Satisfactory/No Credit

CSB 244: Drug Discovery and Development: A Case-based Approach

Provides an overview of the drug discovery and development process through use of case examples--successful and unsuccessful attempts to integrate the scientific, clinical, regulatory, and commercial requirements to bring a new drug to patients. Focus on the complex array of independent tasks that must be accomplished to bring a new drug to the clinic. Specific cases discussed in a seminar format.
Terms: alternate years, given next year | Units: 2 | Grading: Medical Option (Med-Ltr-CR/NC)
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