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COMPMED 80N: Animal behavior: sex, death, and sometimes food!

Preference to freshman. Behavior is what makes animals special (thirsty plants don't walk to water), but why do animals behave the way they do? What does their behavior tell us about their inner lives, and about ourselves? What do lipstick and cuckoos and fireflies have in common? Why would nobody want to be a penguin? What do mice say to each other in their pee-mail? Learning how to think about questions like these gives us a unique perspective on the natural world. Format: Discussion and criticism of video examples, documentaries, and research papers. Topics: History and approaches to animal behavior; development of behavior, from genetics to learning; mechanisms of behavior, from neurons to motivation; function of behavior, from honest signals to selfish genes; the phylogeny of behavior, from domestication to speciation; and modern applications of behavior, from abnormal behavior, to conservation, to animal welfare, and animal consciousness.
Terms: Aut, Spr | Units: 3 | UG Reqs: WAY-SMA | Grading: Letter or Credit/No Credit
Instructors: ; Garner, J. (PI)

COMPMED 87Q: Laboratory Mouse in Biomedical Research

Preference to sophomores. Focus is on the laboratory mouse, a widely used and important research model. Topics include the ethics of animal use in research; the natural history, origin and husbandry of the mouse; characteristics of key mouse strains; its anatomy and physiology; common diseases and their effects on research; coat color genetics relative to human diseases; immunodeficient mouse models; and genetic engineering of mice. The laboratory includes necropsy, handling, introduction to anesthesia and surgery, identification methods, and common research techniques using live and dead mice. Enrollment limited to 14 students.
Terms: Aut | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA | Grading: Letter or Credit/No Credit
Instructors: ; Nagamine, C. (PI)

COMPMED 107: Comparative Brain Evolution (COMPMED 207)

Functional organization and evolution of the vertebrate nervous system. Topics include paleoneurology, cladistic analysis, allometry, mosaic versus concerted evolution, and evolution of brain region structure, connectivity, and neurons. Comparisons between structure and function of vertebrate forebrains including hippocampi. Evolution of the primate visual and sensorimotor central nervous system as related to vocalization, socialization, and intelligence.
Terms: Aut | Units: 4 | Grading: Medical Option (Med-Ltr-CR/NC)

COMPMED 110: Pre-Vet Advisory

For students interested in a career in veterinary medicine. How to meet the academic and practical experience prerequisites for admission to veterinary school. Networking with other pre-vet students. Periodic group meetings with guest speakers presenting career options in veterinary medicine. Prerequisite: consent of instructor.
Terms: Aut, Win, Spr | Units: 1 | Repeatable for credit | Grading: Satisfactory/No Credit
Instructors: ; Bouley, D. (PI)

COMPMED 198: Undergraduate Directed Reading in Comparative Medicine

May be taken as a prelude to research and may also involve participation in a lab or research group seminar and/or library research.
Terms: Aut, Win, Spr, Sum | Units: 1-3 | Repeatable for credit | Grading: Letter or Credit/No Credit

COMPMED 199: Undergraduate Research

Investigations sponsored by individual faculty members. Prerequisite: consent of instructor.
Terms: Aut, Win, Spr, Sum | Units: 1-3 | Repeatable for credit | Grading: Letter or Credit/No Credit

COMPMED 200: One Health Journal Club

Participants report on and review scientific articles published in peer reviewed journals. Focus is on manuscripts which report basic and mechanistic discoveries, animal modeling and translational research. The objective is to introduce MLAS students to critical scientific review of hypothesis-based research and experimental design, data analysis and interpretation. Enrollment limited to undergraduate and graduate students currently matriculated or planning to enroll in the MS in Laboratory Animal Science degree program.
Terms: Aut, Win, Spr, Sum | Units: 1 | Repeatable for credit | Grading: Medical Satisfactory/No Credit
Instructors: ; Hestrin, S. (PI)

COMPMED 202: Research Biomethodology for Laboratory Animal Science

Emphasis is on providing introductory training and practical, hands-on research animal biomethodology. Topics include basic care and principals guiding the use of research animals, animal health and welfare, enrichment, basic mouse handling, rodent breeding, and the principals of rodent aseptic surgery and anesthesia. The objective of this course is to teach basic skills in animal handling, animal care and biomethodological research techniques. Content delivered online and in-person.
Terms: Aut, Win, Spr | Units: 2 | Repeatable for credit | Grading: Medical Satisfactory/No Credit
Instructors: ; Pacharinsak, C. (PI)

COMPMED 207: Comparative Brain Evolution (COMPMED 107)

Functional organization and evolution of the vertebrate nervous system. Topics include paleoneurology, cladistic analysis, allometry, mosaic versus concerted evolution, and evolution of brain region structure, connectivity, and neurons. Comparisons between structure and function of vertebrate forebrains including hippocampi. Evolution of the primate visual and sensorimotor central nervous system as related to vocalization, socialization, and intelligence.
Terms: Aut | Units: 4 | Grading: Medical Option (Med-Ltr-CR/NC)

COMPMED 209: Laboratory Animal Medicine Seminar

Focuses on husbandry, care and diseases of major laboratory animal species (rodents, fish and amphibians, swine, sheep, rabbits, monkeys); regulatory and compliance, applied principals of animal modeling, and factors that influence animal research, animal behavior and research reproducibility. The objective of this course is to provide students with an overview of the history of laboratory animal science, current industry standards and practices, and the fundamentals of laboratory animal diseases. Department consent required for enrollment. May be repeated for credit.
Terms: Aut, Win, Spr, Sum | Units: 2 | Repeatable for credit | Grading: Medical Option (Med-Ltr-CR/NC)
Instructors: ; Felt, S. (PI)

COMPMED 211: Biostatistics for the Life Sciences

Emphasis is on real-world experimental design and analysis in the life sciences, with particular focus on modern techniques that maximize power and minimize sample size, and avoiding common errors contributing to false discovery and the reproducibility crisis. This is a flipped-classroom. Class time is devoted to discussion of assigned reading (primarily Grafen & Hailsm 2002 "Modern statistics for the life sciences"), critique of papers, working through example data sets, and developing analyses for the students' own research data. The objective is to provide MLAS students with a fundamental understanding of basic statistics, particularly as applied to the design and planning of animal-based research projects. Enrollment is limited to MLAS students, unless student has course director consent.
Terms: Aut | Units: 2 | Grading: Medical Satisfactory/No Credit
Instructors: ; Garner, J. (PI)

COMPMED 260: Masters Laboratory Animal Science Practicum/Laboratory Research

Research laboratory and clinical service (pathology, diagnostic laboratory, surgery, husbandry, anesthesiology, aquatics, facility business and management, etc.), quarterly rotations for students enrolled in the Master's of Laboratory Animal Science program. The objective of this course is to provide students with hands on experience in research laboratories using animal models and to provide experience working in the daily operations of a large, veterinary service center. Fulfills the practicum and research requirements of MLAS students.
Terms: Aut, Win, Spr, Sum | Units: 1-15 | Repeatable for credit | Grading: Medical Option (Med-Ltr-CR/NC)

COMPMED 290: MLAS Career Development

Focus is on career development for graduate students and trainees enrolled in a trainee program in the Department of Comparative Medicine. Seminar topics include career pathways in laboratory animal science, resume preparation, manuscript preparation and authorship, life in academics, life in industry and biopharma, regulatory agencies, veterinary and medical school. Speakers include faculty, speakers from industry and pharmaceutical companies, veterinary school and medical school graduates, regulatory and compliance professionals, research scientists, and animal research program/laboratory managers. Students may choose to shadow veterinary clinical faculty or rotate through basic science laboratory, by special arrangement. The objective is to introduce students to the multiple career pathways available to individuals with advanced training in laboratory animal science. May be taken up to six quarters.
Terms: Aut, Win, Spr | Units: 1-6 | Repeatable for credit | Grading: Medical Option (Med-Ltr-CR/NC)

COMPMED 299: Directed Reading in Comparative Medicine

Prerequisite: consent of instructor. (Staff)
Terms: Aut, Win, Spr, Sum | Units: 1-18 | Repeatable for credit | Grading: Medical Option (Med-Ltr-CR/NC)

COMPMED 370: Medical Scholars Research

Provides an opportunity for student and faculty interaction, as well as academic credit and financial support, to medical students who undertake original research. Enrollment is limited to students with approved projects.
Terms: Aut, Win, Spr, Sum | Units: 4-18 | Repeatable for credit | Grading: Medical School MD Grades

COMPMED 399: Graduate Research

Investigations sponsored by individual faculty members.Opportunities are available in comparative medicine and pathology, immuno-histochemistry, electron microscopy, molecular genetics, quantitative morphometry, neuroanatomy and neurophysiology of the hippocampus, pathogenesis of intestinal infections, immunopathology, biology of laboratory rodents, anesthesiology of laboratory animals, gene therapy of animal models of neurodegenerative diseases, and development and characterization of transgenic animal models. Prerequisite: consent of instructor.
Terms: Aut, Win, Spr, Sum | Units: 1-18 | Repeatable for credit | Grading: Medical Option (Med-Ltr-CR/NC)

COMPMED 801: TGR Project

Terms: Aut, Win, Spr, Sum | Units: 0 | Repeatable for credit | Grading: TGR
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