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CHEM 5: Big Ideas: Conversations with Stanford's Own Nobel Laureates & MacArthur "Genius" Fellows (ECON 3, SOC 5)

10 weekly one-on-one conversations with Nobel Laureates and MacArthur fellows, talking about their life story, how they got to their ideas, what they discovered, how the world is a better place as a result, what advice they have for students and young researchers, etc. Readings related to guest research will be assigned. Open to undergraduate and graduate students.
Terms: Aut | Units: 1

CHEM 10: Exploring Research and Problem Solving Across the Sciences

Development and practice of critical problem solving and study skills using a wide variety of scientific examples that illustrate the broad yet integrated nature of current research. Students will build a problem solving tool-kit and apply chemical and mathematical concepts to solve problems related to energy, climate change, water resources, medicine, and food & nutrition. Note: course offered in August prior to start of fall quarter, and only Leland Scholar Program participants will register.
Terms: Aut | Units: 1

CHEM 31A: Chemical Principles I

31A is the first course in a two-quarter sequence designed to provide a robust foundation in key chemical principles for students with a basic background in high school chemistry, who have already placed into Math 19 or higher. The course engages students in group problem-solving activities throughout the class periods to deepen their ability to analyze and solve chemical problems. Students will also participate in a weekly laboratory activity that will immediately apply and expand upon classroom content. Labs and write-ups provide practice developing conceptual models that can explain qualitatively and quantitatively a wide range of chemical phenomena. The course will introduce a common language of dimensional analysis, stoichiometry, and molecular naming that enables students to write chemical reactions, quantify reaction yield, and calculate empirical and molecular formulas. Stoichiometry will be immediately reinforced through a specific study of gases and their properties. Students will also build a fundamental understanding of atomic and molecular structure by identifying interactions among nuclei, electrons, atoms and molecules. Through both lab and in-class exploration, students will learn to explain how these interactions determine the structures and properties of pure substances and mixtures using various bonding models including Lewis Dot, VSEPR, and Molecular Orbital Theory. Students will identify and quantitate the types and amounts of energy changes that accompany these interactions, phase changes, and chemical reactions, as they prepare to explore chemical dynamics in greater depth in 31B. Special emphasis will be placed on applying content and skills to real world applications such as estimating the carbon efficiency of fossil fuels, understanding hydrogen bonding and other interactions critical to DNA, and calculating the pressure exerted on a deep-sea diver. Prerequisites: Math 18 and Chem11 or placement into Chem31A with Autumn General Chemistry Placement test. All students who are interested in taking general chemistry at Stanford must take the General Chemistry Placement Test before the Autumn quarter begins, regardless of chemistry background, to enroll.
Terms: Aut, Sum | Units: 5 | UG Reqs: GER: DB-NatSci, WAY-SMA

CHEM 31M: Chemical Principles: From Molecules to Solids

A one-quarter course for students who have taken chemistry previously. This course will introduce the basic chemical principles that dictate how and why reactions occur and the structure and properties of important molecules and extended solids that make up our world. As the Central Science, a knowledge of chemistry provides a deep understanding of concepts in fields ranging from materials, environmental science, and engineering to pharmacology and metabolism. Discussions of molecular structure will describe bonding models including Lewis structures, resonance, crystal-field theory, and molecular-orbital theory. We will reveal the chemistry of materials of different dimensionality, with an emphasis on bonding, and electronic structure of molecules and solids. We will also discuss the kinetics and thermodynamics that govern reactivity and dictate solubility and acid-base equilibria. A two-hour weekly laboratory section accompanies the course to introduce laboratory techniques and reiterate lecture concepts through hands-on activities. Specific discussions will include the structure, properties, and applications of molecules used in medicine, perovskites used in solar cells, and the dramatically different properties of materials with the same composition (for example: diamond, graphite, graphene). There will be three lectures and one two-hour laboratory session each week. The course will assume familiarity with stoichiometry, unit conversions, gas laws, and thermochemistry. All students who are interested in taking general chemistry at Stanford must take the Autumn 2021 General Chemistry Placement Test before the Autumn quarter begins, regardless of chemistry background. Same as: MATSCI 31
Terms: Aut | Units: 5 | UG Reqs: GER: DB-NatSci, WAY-SMA

CHEM 31S: STEMentors in Chemistry

STEMentors in Chemistry has been designed to provide timely support for students in CHEM 31A with study and problem-solving skills applicable in both chemistry and STEM courses in general. Students will join a small cohort of other CHEM31A students looking to build community with and support other students in STEM. Weekly sections will focus on group activities and individual check-ins facilitated by a peer mentor who has previously taken the CHEM 31A/B sequence. These activities are designed to normalize challenging experiences within a college science course, build key study skills such as how to effectively review lecture notes and practice problems, prepare for and reflect on exams, and develop a consistent problem-solving process that will build student confidence over the quarter. Students should enroll in a weekly mentor section, occurring on Thursdays. You can read more about our individual mentors here:https://chemistrystementors.sites.stanford.edu/people-0. Co-Requisite: CHEM 31A
Terms: Aut | Units: 1

CHEM 90: Directed Instruction/Reading

Undergraduates pursue a reading program under supervision of a faculty member in Chemistry; may also involve participation in lab. Prerequisites: superior work in CHEM 31A, 31B, 31M, or 33; and consent of instructor.
Terms: Aut, Win, Spr, Sum | Units: 1-2 | Repeatable 4 times (up to 8 units total)

CHEM 121: Understanding the Natural and Unnatural World through Chemistry

Students enrolled in this course will appreciate the transformative power of molecular science on the modern world and how foundational knowledge of chemistry enables profound discoveries in biological, pharmaceutical, agrochemical, engineering, energy, and materials science research. This course integrates the lessons of CHEM 31 and CHEM 33 through an examination of the structure-function properties of carbon-based molecules. Specific emphasis is given to the chemistry of carbonyl- and amine-derived compounds, polyfunctionalized molecules, reaction kinetics and thermodynamics, mechanistic arrow-pushing, and retrosynthetic analysis. Students will be empowered with a conceptual understanding of chemical reactivity, physical organic chemistry, and the logic of chemical synthesis. The singular nature of molecular design and synthesis to make available functional molecules and materials will be revealed. A three-hour lab section provides hands on experience with modern chemical methods for preparative and analytical chemistry. Prerequisite CHEM 33 or co-requisite CHEM 100.
Terms: Aut, Spr, Sum | Units: 5 | UG Reqs: GER: DB-NatSci

CHEM 123: Organic Polyfunctional Compounds

Analysis of molecular symmetry and spectroscopy, aromaticity, aromatic reactivity, heterocyclic chemistry, chemistry of peptides and DNA. Prerequisite: CHEM 121
Terms: Aut | Units: 3 | UG Reqs: GER: DB-NatSci
Instructors: ; Kanan, M. (PI)

CHEM 124: Organic Chemistry Laboratory

This is a laboratory course that serves as a stepping stone toward independent research in organic chemistry. Through several 1-2 step syntheses, this course trains students on basic organic laboratory techniques on purification of products, including extraction, distillation, recrystallization, thin layer chromatography, and column chromatography, as well as characterization of product structures using IR, GC-MS, and NMR spectroscopy. This course reviews MS, IR, and 1H and 13C NMR spectroscopy knowledge from Chem 33 and 121 with an emphasis on the practical interpretation of spectra, so that students can become independent in using these techniques to identify the purity and structures of organic compounds.Prerequisite: Chem 121. Corequisite: Chem 123.
Terms: Aut | Units: 3 | UG Reqs: GER: DB-NatSci
Instructors: ; Xia, Y. (PI)

CHEM 173: Physical Chemistry II

Introduction to quantum chemistry: the basic principles and applications of quantum theory, Dirac notation, momentum of a free particle and wave packets, the uncertainty principle, time independent and time dependent perturbation theory, harmonic oscillator in molecules and solids, absorption and emission spectroscopy, the variational method, atomic energy calculations, and introduction to basic computational chemistry methods. Prerequisites: CHEM 171; PHYSICS 43.
Terms: Aut | Units: 3 | UG Reqs: GER: DB-NatSci

CHEM 174: Physical chemistry laboratory I (CHEM 274)

Introduction to modern electrochemical measurement in a hands-on, laboratory setting. Students will assemble simple electrochemical cells and build simple circuits to digitize the data they collect. Students will work with reference, working, and counter electrodes with macro, micro and ultramicro geometries, salt bridges, ion-selective membranes, electrometers, and potentiostats. Prerequisites: CHEM 171 or equivalent.
Terms: Aut | Units: 3 | UG Reqs: GER: DB-NatSci
Instructors: ; Kromer, M. (PI)

CHEM 181: Biochemistry I (CHEMENG 181, CHEMENG 281)

Structure and function of major classes of biomolecules, including proteins, carbohydrates and lipids. Mechanistic analysis of properties of proteins including catalysis, signal transduction and membrane transport. Students will also learn to critically analyze data from the primary biochemical literature. Satisfies Central Menu Area 1 for Bio majors. Prerequisites: Chem 121.
Terms: Aut | Units: 4 | UG Reqs: GER: DB-NatSci
Instructors: ; Cegelski, L. (PI)

CHEM 221: Advanced Organic Chemistry I

From molecular medicine to molecular anthropology and all sciences in between, Chemistry in particular and molecular science in general are driven by one's understanding of structure and how structure relates to properties, reactivities (mechanisms) and activities and by ones ability to make molecules. This course integrates the mechanistic and structural foundations of organic chemistry with an emphasis on reactive intermediates and reaction mechanisms, strategies for the design and synthesis of complex molecules and concepts for innovative problem solving. An additional emphasis is placed on generating ideas and proposals directed at identifying and solving problems in science as required for a career in molecular science.
Terms: Aut | Units: 3 | Repeatable 2 times (up to 6 units total)

CHEM 255: Advanced Inorganic Chemistry (CHEM 155)

Chemical reactions of organotransition metal complexes and their role in homogeneous catalysis. Analogous patterns among reactions of transition metal complexes in lower oxidation states. Physical methods of structure determination. Prerequisite: one year of physical chemistry.
Terms: Aut | Units: 3

CHEM 257: Bio-Inorganic Chemistry (BIOPHYS 297)

(Formerly Chem 297) Overview of metal sites in biology. Metalloproteins as elaborated inorganic complexes, their basic coordination chemistry and bonding, unique features of the protein ligand, and the physical methods used to study active sites. Active site structures are correlated with function (election transfer; dioxygen binding, activation and reduction to water). Prerequisites: Chem 153 and Chem 173, or equivalents.
Terms: Aut | Units: 3

CHEM 263: Machine Learning for Chemical and Dynamical Data

Introduction to machine learning methodologies for the chemical sciences, with an emphasis on the current state-of-the-art for applications to both experimental and computational data. The course will be hands-on and final projects will be a major component of the coursework. Material covered will include neural networks, classification and regression, image analysis, graph neural networks, learning potential energy surfaces, coarse-graining, Monte Carlo simulation, and applications to quantum chemistry and molecular dynamics. Prerequisite: knowledge of undergraduate level quantum mechanics and statistical mechanics at the levels of Chem 173 and Chem 175. Experience with Python highly recommended.
Terms: Aut | Units: 3

CHEM 271: Advanced Physical Chemistry

Introduction to quantum chemistry: the basic principles and applications of quantum theory, Dirac notation, momentum of a free particle and wave packets, the uncertainty principle, time independent and time dependent perturbation theory, harmonic oscillator in molecules and solids, absorption and emission spectroscopy, the variational method, atomic energy calculations, and introduction to basic computational chemistry methods. Prerequisites: CHEM 171; PHYSICS 43.
Terms: Aut | Units: 3

CHEM 287: Visualizing Biomolecules (BIO 218)

(This course is for graduate students only. ) Leveraging high-resolution structural techniques to visualize and understand the function and mechanisms of biological molecules, with an emphasis on proteins. The course covers the theory of modern x-ray diffraction and electron microscopy for macromolecules, provides hands-on experimentation with both techniques and presents case studies from the literature to highlight how these techniques can be leveraged to reveal the mechanisms of action of some of nature's most powerful catalysts.
Terms: Aut | Units: 5

CHEM 299: Teaching of Chemistry

Required of all teaching assistants in Chemistry. Techniques of teaching chemistry by means of lectures and labs.
Terms: Aut, Win, Spr, Sum | Units: 1-3 | Repeatable for credit

CHEM 300: Department Colloquium

Required of graduate students. May be repeated for credit.
Terms: Aut, Win, Spr | Units: 1 | Repeatable 15 times (up to 15 units total)

CHEM 301: Research in Chemistry

Required of graduate students who have passed the qualifying examination. Open to qualified graduate students with the consent of the major professor. Research seminars and directed reading deal with newly developing areas in chemistry and experimental techniques. May be repeated for credit. Search for adviser name on Axess.
Terms: Aut, Win, Spr, Sum | Units: 2 | Repeatable for credit

CHEM 329: Organic Chemistry Seminar

(Formerly 229) Required of graduate students majoring in organic chemistry. Students giving seminars register for CHEM 231.
Terms: Aut, Win, Spr | Units: 1 | Repeatable 11 times (up to 11 units total)
Instructors: ; Burns, N. (PI)

CHEM 359: Inorganic Chemistry Seminar

(Formerly 259) Required of graduate students majoring in inorganic chemistry.
Terms: Aut, Win, Spr | Units: 1 | Repeatable 15 times (up to 15 units total)

CHEM 379: Physical Chemistry Seminar

(Formerly 279) Required of graduate students majoring in physical chemistry. May be repeated for credit.
Terms: Aut, Win, Spr | Units: 1 | Repeatable 15 times (up to 15 units total)

CHEM 390: Curricular Practical Training for Chemists

For Chemistry majors who need work experience as part of their program of study. Confer with Chem student services office for signup.
Terms: Aut, Win, Spr, Sum | Units: 1 | Repeatable 2 times (up to 2 units total)
Instructors: ; Cegelski, L. (PI)
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