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HRP 89Q: Introduction to Cross Cultural Issues in Medicine

Preference to sophomores. Introduction to social factors that impact health care delivery, such as ethnicity, immigration, language barriers, and patient service expectations. Focus is on developing a framework to understand culturally unique and non-English speaking populations in the health care system.
Terms: Win | Units: 3 | UG Reqs: GER:EC-AmerCul
Instructors: ; Corso, I. (PI)

HRP 198: Unite, Empower, Experience: Understanding the Universality of Women's Health

Directed reading course reading. Focus is on the impact of the unique challenges women face in the healthcare system on women and their communities. Examines the current state of women's health from global perspective, considering: community health, health policy, and the medical technology sector.
Terms: Win | Units: 1

HRP 206: Meta-research: Appraising Research Findings, Bias, and Meta-analysis (MED 206, STATS 211)

Open to graduate, medical, and undergraduate students. Appraisal of the quality and credibility of research findings; evaluation of sources of bias. Meta-analysis as a quantitative (statistical) method for combining results of independent studies. Examples from medicine, epidemiology, genomics, ecology, social/behavioral sciences, education. Collaborative analyses. Project involving generation of a meta-research project or reworking and evaluation of an existing published meta-analysis. Prerequisite: knowledge of basic statistics.
Terms: Win | Units: 3

HRP 207: Introduction to Concepts and Methods in Health Services and Policy Research I

Primarily for medical students in the Health Services and Policy Research scholarly concentration. Topics include health economics, statistics, decision analysis, study design, quality measurement, cost benefit and effectiveness analysis, and evidence based guidelines.
Terms: Aut | Units: 3
Instructors: ; Haberland, C. (PI)

HRP 208: Introduction to Concepts and Methods in Health Services and Policy Research II

Primarily for medical students in the Health Services and Policy Research scholarly concentration; continuation of 207. Topics include health economics, statistics, decision analysis, study design, quality measurement, cost benefit and effectiveness analysis, and evidence based guidelines. Recommended: 207.
Terms: Win | Units: 3
Instructors: ; Haberland, C. (PI)

HRP 212: Cross Cultural Medicine

Developing interviewing and behavioral skills needed to facilitate culturally relevant health care across all population groups. Discussions focus on explicit and implicit cultural influences operating in formal and informal medical contexts.
Terms: Spr | Units: 3
Instructors: ; Corso, I. (PI)

HRP 213: Writing in the Sciences

Primarily for medical students in the Clinical Research Scholarly concentration; open to graduate students except Epidemiology graduate students. Development of research questions and plans for statistical analysis. Study design, sample size and power calculations, and statistical analysis of study data. Analytic methods to carry out statistical power and sample size calculations. Prerequisites: 225, and 258 or 259, or consent of instructor.
Terms: Aut | Units: 2-3
Instructors: ; Sainani, K. (PI)

HRP 214: Scientific Writing

Step-by-step through the process of writing and publishing a scientific manuscript. How to write effectively, concisely, and clearly. Preparation of an actual scientific manuscript. Students are encouraged to bring a manuscript on which they are currently working to develop and polish throughout the course.
Terms: Win | Units: 2-3
Instructors: ; Sainani, K. (PI)

HRP 216: Analytical and Practical Issues in the Conduct of Clinical and Epidemiologic Research

Topics include: advanced aspects of study design and data analyses; development of health measurement instruments; methods of summarizing literature and quantifying effect sizes; and multivariable nature of health events in human populations. 3 units requires a term paper. Prerequisites: 225, and 258 or 261, or consent of instructor.
Terms: Spr | Units: 2-3
Instructors: ; Popat, R. (PI)

HRP 221: Law and the Biosciences: Genetics

(Same as LAW 480) Open to all law or medical students; other graduate students by consent of the instructor. Focus is on ethical, legal, and social issues arising from advances in our knowledge of human genetics. Includes forensic uses of genetics, genetic testing, widespread whole genome sequencing, the consequences of genetics for human reproduction, and the ethics of genomic biobanks for research. Research paper required.
| Units: 3

HRP 222A: Advising Congress on Health Policy

(Same as LAW 413L) Focus on conducting research on national health policy problems for the Medicare Payment Advisory Commission, or MedPAC. Students work in teams with lawyers and PhD economists from MedPAC, resident and fellow physicians from Stanford Hospital, and other students from throughout the University on exanding the healthcare workforce through reform of states' scope of practice regulation or designing antitrust policy to achieve the benefits of coordination and avoid the costs of consolidation. Application required.
Terms: Aut | Units: 1

HRP 222B: Advising Congress on Health Policy

(Same as LAW 413L) Focus on conducting research on national health policy problems for the Medicare Payment Advisory Commission, or MedPAC. Students work in teams with lawyers and PhD economists from MedPAC, resident and fellow physicians from Stanford Hospital, and other students from throughout the University on exanding the healthcare workforce through reform of states' scope of practice regulation or designing antitrust policy to achieve the benefits of coordination and avoid the costs of consolidation. Application required.
Terms: Win | Units: 2

HRP 223: Epidemiologic Analysis: Data Management and Statistical Programming

The skills required for management and analysis of biomedical data. Topics include importing and exporting data from multiple database systems, visualizing and cleaning data, data management for multicenter projects, and data security. Introduction to applied statistical programming relevant to epidemiologic and clinical research. No previous programming experience required.
Terms: Aut | Units: 2-3

HRP 225: Design and Conduct of Clinical and Epidemiologic Studies

Intermediate-level. The skills to design, carry out, and interpret epidemiologic studies, particularly of chronic diseases. Topics: epidemiologic concepts, sources of data, cohort studies, case-control studies, cross-sectional studies, sampling, estimating sample size, questionnaire design, and the effects of measurement error. Prerequisite: A basic/introductory course in statistics or consent of instructor.
Terms: Aut | Units: 3-4
Instructors: ; Popat, R. (PI)

HRP 226: Advanced Epidemiologic and Clinical Research Methods

The principles of measurement, measures of effect, confounding, effect modification, and strategies for minimizing bias in clinical and epidemiologic studies. Students enrolled for 4 units complete an additional assignment or paper. Prerequisite: 225 or consent of instructor.
Terms: Win | Units: 3-4
Instructors: ; Nelson, L. (PI)

HRP 228: Genetic Epidemiology

Provides framework for physicians, epidemiologists, and other scientists to interpret the literature and incorporate genetic information into human disease research. Topics include: common genetic measures, approaches to finding disease genes, study design and analysis issues, genome-wide association studies, meta-analysis of genetic studies, genetic risk prediction, and applications of new genomic technologies. Includes reading seminal papers in genetic epidemiology.
Terms: Spr | Units: 2

HRP 236: Epidemiology Research Seminar

Weekly forum for ongoing epidemiologic research by faculty, staff, guests, and students, emphasizing research issues relevant to disease causation, prevention, and treatment. May be repeated for credit.
Terms: Aut, Win, Spr | Units: 1 | Repeatable for credit

HRP 238: Genes and Environment in Disease Causation: Implications for Medicine and Public Health (HUMBIO 159)

The historical, contemporary, and future research and practice among genetics, epidemiology, clinical medicine, and public health as a source of insight for medicine and public health. Genetic and environmental contributions to multifactorial diseases; multidisciplinary approach to enhancing detection and diagnosis. The impact of the Human Genome Project on analysis of cardiovascular and neurological diseases, and cancer. Ethical and social issues in the use of genetic information. Prerequisite: basic course in genetics; for undergraduates, Human Biology core or equivalent or consent of instructor.
Terms: Win | Units: 2-3
Instructors: ; Popat, R. (PI)

HRP 239: Statistical Methods for Group Comparisons and Causal Inference (EDUC 260X, STATS 209)

Critical examination of statistical methods in social science applications, especially for cause and effect determinations. Topics: path analysis, multilevel models, matching and propensity score methods, analysis of covariance, instrumental variables, compliance, longitudinal data, mediating and moderating variables. See http://www-stat.stanford.edu/~rag/stat209. Prerequisite: intermediate-level statistical methods
Terms: Win | Units: 3
Instructors: ; Rogosa, D. (PI)

HRP 241: Measuring Global Health (HUMBIO 129M, MED 231)

Open to MD, graduate, and undergraduate students. Assessing the global burden of disease, its distribution among and within countries, its causes, and appropriate interventions requires rigorous quantitative approaches. This course develops skills in these areas by critically examining questions like: How do we know who is sick and where? How are risk factors incorporated into our projections of future disease trends? How do we combine mortality and morbidity in a meaningful way? What works for improving health efficiently? Workshops build familiarity with relevant data and their analysis. Prerequisite: coursework in statistics, biostatistics, quantitative epidemiology, econometrics, or equivalent.
Last offered: Spring 2013 | Units: 4 | Repeatable for credit

HRP 251: Design and Conduct of Clinical Trials

The rationale for phases 1-3 clinical trials, the recruitment of subjects, techniques for randomization, data collection and endpoints, interim monitoring, and reporting of results. Emphasis is on the theoretical underpinnings of clinical research and the practical aspects of conducting clinical trials.
Terms: Spr | Units: 3

HRP 252: Outcomes Analysis (BIOMEDIN 251, MED 252)

Methods of conducting empirical studies which use large existing medical, survey, and other databases to ask both clinical and policy questions. Econometric and statistical models used to conduct medical outcomes research. How research is conducted on medical and health economics questions when a randomized trial is impossible. Problem sets emphasize hands-on data analysis and application of methods, including re-analyses of well-known studies. Prerequisites: one or more courses in probability, and statistics or biostatistics.
Terms: Spr | Units: 4

HRP 256: Economics of Health and Medical Care (BIOMEDIN 156, BIOMEDIN 256, ECON 126)

Institutional, theoretical, and empirical analysis of the problems of health and medical care. Topics: demand for medical care and medical insurance; institutions in the health sector; economics of information applied to the market for health insurance and for health care; measurement and valuation of health; competition in health care delivery. Graduate students with research interests should take ECON 249. Prerequisites: ECON 50 and ECON 102A or Stats 116 or the equivalent. Recommended: ECON 51.
Terms: Aut, Win | Units: 5

HRP 258: Introduction to Probability and Statistics for Clinical Research

Open to medical and graduate students; required of medical students in the Clinical Research Scholarly Concentration. Tools to evaluate medical literature. Topics include random variables, expectation, variance, probability distributions, the central limit theorem, sampling theory, hypothesis testing, confidence intervals, correlation, regression, analysis of variance, and survival analysis.
Terms: Spr | Units: 3
Instructors: ; Sainani, K. (PI)

HRP 259: Introduction to Probability and Statistics for Epidemiology

Topics: random variables, expectation, variance, probability distributions, the central limit theorem, sampling theory, hypothesis testing, confidence intervals. Correlation, regression, analysis of variance, and nonparametric tests. Introduction to least squares and maximum likelihood estimation. Emphasis is on medical applications. Differential between 3 and 4 units is the amount of out-of-class work required.
Terms: Aut | Units: 3-4
Instructors: ; Sainani, K. (PI)

HRP 260A: Workshop in Biostatistics (STATS 260A)

Applications of statistical techniques to current problems in medical science. To receive credit for one or two units, a student must attend every workshop. To receive two units, in addition to attending every workshop, the student is required to write an acceptable one page summary of two of the workshops, with choices made by the student.
Terms: Aut | Units: 1-2 | Repeatable for credit

HRP 260B: Workshop in Biostatistics (STATS 260B)

Applications of statistical techniques to current problems in medical science. To receive credit for one or two units, a student must attend every workshop. To receive two units, in addition to attending every workshop, the student is required to write an acceptable one page summary of two of the workshops, with choices made by the student.
Terms: Win | Units: 1-2 | Repeatable for credit

HRP 260C: Workshop in Biostatistics (STATS 260C)

Applications of statistical techniques to current problems in medical science. To receive credit for one or two units, a student must attend every workshop. To receive two units, in addition to attending every workshop, the student is required to write an acceptable one page summary of two of the workshops, with choices made by the student.
Terms: Spr | Units: 1-2 | Repeatable for credit

HRP 261: Intermediate Biostatistics: Analysis of Discrete Data (BIOMEDIN 233, STATS 261)

Methods for analyzing data from case-control and cross-sectional studies: the 2x2 table, chi-square test, Fisher's exact test, odds ratios, Mantel-Haenzel methods, stratification, tests for matched data, logistic regression, conditional logistic regression. Emphasis is on data analysis in SAS. Special topics: cross-fold validation and bootstrap inference.
Terms: Win | Units: 3
Instructors: ; Sainani, K. (PI)

HRP 262: Intermediate Biostatistics: Regression, Prediction, Survival Analysis (STATS 262)

Methods for analyzing longitudinal data. Topics include Kaplan-Meier methods, Cox regression, hazard ratios, time-dependent variables, longitudinal data structures, profile plots, missing data, modeling change, MANOVA, repeated-measures ANOVA, GEE, and mixed models. Emphasis is on practical applications. Prerequisites: basic ANOVA and linear regression.
Terms: Spr | Units: 3
Instructors: ; Sainani, K. (PI)

HRP 263: Advanced Decision Science Methods and Modeling in Health (MED 263)

Advanced methods currently used in published model-based cost-effectiveness analyses in medicine and public health, both theory and technical applications. Topics include: Markov and microsimulation models, model calibration and evaluation, and probabilistic sensitivity analyses. Prerequisites: a course in probability, a course in statistics or biostatistics, a course on cost-effectiveness such as HRP 392, a course in economics, and familiarity with decision modeling software such as TreeAge.
Terms: Spr | Units: 3

HRP 280: Spanish for Medical Students (SPANLANG 121M)

First quarter of three-quarter series. Goal is a practical and culturally appropriate command of spoken Spanish. Emphasis is on taking the medical history. Topics include the human body, hospital procedures, diagnostics, food, and essential doctor-patient phrases when dealing with Spanish-speaking patients. Series can be taken independently, depending on the level of prior knowledge. Offered to undergraduates for 3 units(2 units for medical students).
Terms: Aut | Units: 3
Instructors: ; Corso, I. (PI)

HRP 281: Spanish for Medical Students (SPANLANG 122M)

Second quarter of three-quarter series.Goal is a practical and culturally appropriate command of spoken Spanish. Emphasis is on performing a physical examination. Topics include the human body, hospital procedures, diagnostics, food, and essential doctor-patient phrases when dealing with Spanish-speaking patients. Series can be taken independently, depending on the level of prior knowledge. Offered to undergraduates for 3 units(2 units for medical students).
Terms: Win | Units: 2
Instructors: ; Corso, I. (PI)

HRP 282: Spanish for Medical Students (SPANLANG 123M)

Third quarter of three-quarter series. Goal is a practical and culturally appropriate command of spoken Spanish. Emphasis is on different specialties and medical conditions. Topics include the human body, hospital procedures, diagnostics, food, and essential doctor-patient phrases when dealing with Spanish-speaking patients. Series can be taken independently, depending on the level of prior knowledge. Offered to undergraduates for 3 units(2 units for medical students).
Terms: Spr | Units: 2-3
Instructors: ; Corso, I. (PI)

HRP 28SI: Alternative Spring Break: Prevention, Treatment, and Policy Perspectives on Alzheimer's Disease

Examines four aspects of Alzheimer's disease. Goal is to give participants a clearer sense of the struggle that patients actually feel and experience during the progression of the disease. Also explores difficulties and issues that many relatives face in assuming the responsibility of full-time caregiver for an Alzheirmers patient. Addresses ethical considerations on genetic testing, should these advances be embraced or should we be wary of the knowledge they may bring? Finally, explores the notion of service through engaged scholarship by exposing oneself to cutting-edge discoveries as researchers attempt to unravel the puzzle.
| Units: 1

HRP 290: Advanced Medical Spanish Oral Communication

Enrollment limited to medical students. Designed to further develop linguistic skills, covering all medical specialties according to student needs. Sessions also include topics on patient education and diseases, such as diabetes, asthma, TB, and CVDs.
Terms: Aut, Win, Spr | Units: 2 | Repeatable for credit
Instructors: ; Corso, I. (PI)

HRP 299: Directed Reading in Health Research and Policy

Epidemiology, health services research, preventive medicine, medical genetics, public health, economics of medical care, occupational or environmental medicine, international health, or related fields. May be repeated for credit. Prerequisite: consent of instructor.
Terms: Aut, Win, Spr, Sum | Units: 1-18 | Repeatable for credit

HRP 370: Medical Scholars Research

Provides an opportunity for student and faculty interaction, as well as academic credit and financial support, to medical students who undertake original research. Enrollment is limited to students with approved projects.
Terms: Aut, Win, Spr, Sum | Units: 4-18 | Repeatable for credit

HRP 391: Health Care Regulation, Finance and Policy (PUBLPOL 231)

(SAME AS LAW 348, MGTECON 331) Provides the legal, institutional, and economic background necessary to understand the financing and production of health services in the U.S. Potential topics include: health reform, health insurance (Medicare and Medicaid, employer-sponsored insurance, the uninsured), medical malpractice and quality regulation, pharmaceuticals, the corporate practice of medicine, regulation of fraud and abuse, and international comparisons.
Terms: Win | Units: 3

HRP 392: Analysis of Costs, Risks, and Benefits of Health Care (BIOMEDIN 432)

(Same as MGTECON 332) For graduate students. How to do cost/benefit analysis when the output is difficult or impossible to measure. How do M.B.A. analytic tools apply in health services? Literature on the principles of cost/benefit analysis applied to health care. Critical review of actual studies. Emphasis is on the art of practical application.
Terms: Aut | Units: 4

HRP 209: FDA's Regulation of Health Care

(Same as LAW 458) Open to law and medical students; other graduate students by consent of instructor. The FDA's regulatory authority over drugs, biologics, medical devices, and dietary supplements. The nature of the pharmaceutical, biotech, medical device, and nutritional supplement industries.
| Units: 2-3

HRP 210: Health Law and Policy

(Same as Law 313) Open to law , medicine, business, and graduate students. Focus this term is on the physician/patient relationship, medical ethics, and public health law.
| Units: 3

HRP 211: Law and the Biosciences: Neuroscience

(Same as LAW 368) Legal, social, and ethical issues arising from advances in neuroscience, including effects upon law and society through improvements in predicting illnesses and behaviors, reading minds through neuroimaging, understanding responsibility and consciousness, treating criminal behavior, and cognitive enhancement.
| Units: 3

HRP 215: Scientific Writing for Basic and Translational Scientists

Teaches students in the basic sciences how to write clearly, concisely, and effectively. Focuses on the process of writing and publishing a scientific manuscript. 3 unit option requires work on a manuscript. Not intended for epidemiology graduate students.
| Units: 2-3

HRP 220: BIOTECHNOLOGY LAW AND POLICY

(Same as LAW 440) Open to all law or medical students; other graduate students by consent of the instructor. Focuses on the biotechnology industry, with some discussion of the "med tech" or medical device industry and the pharmaceutical industry. The life cycle of a biotech firm, from a good idea to a start-up company to FDA approval and beyond. Guest speakers. In addition to a final exam, students are required to participate in a group project during the term, making law and business recommendations about a biotech firm.
| Units: 3

HRP 230: Cancer Epidemiology

Descriptive epidemiology and sources of incidence/mortality data; the biological basis of carcinogenesis and its implications for epidemiologic research; methodological issues relevant to cancer research; causal inference; major environmental risk factors; genetic susceptibility; cancer control; examples of current research; and critique of the literature. 3 units requires paper or project. Prerequisite: 225, or consent of instructor.
| Units: 2-3

HRP 231: Epidemiology of Infectious Diseases

Principles of the transmission of the infectious agents (viruses, bacteria, rickettsiae, mycoplasma, fungi, and protozoan and helminth parasites). The role of vectors, reservoirs, and environmental factors. Pathogen and host characteristics that determine the spectrum of infection and disease. Endemicity, outbreaks, and epidemics of selected infectious diseases. Principles of control and surveillance.
| Units: 3

HRP 255: Observational Studies (STATS 355)

This course will cover statistical methods for the design and analysis of observational studies. Topics for the course will include the potential outcomes framework for causal inference; randomized experiments; methods for controlling for observed confounders in observational studies; sensitivity analysis for hidden bias; instrumental variables; tests of hidden bias; coherence; and design of observational studies.
| Units: 2-3

HRP 268: Genetics and Reproductive Technologies

(Same as LAW 568) Examines the complex interrelationship among legal, political, ethical, and social issues shaping the intersection of genetics, reproductive technologies and reproductive rights. Issues discussed may included, but are not limited to: the commercialization and sale of reproductive materials like sperm, ovum, and surrogacy services; genetic technologies, prenatal genetic screening, and diagnostic testing of offspring; criminalization of reproductive decision-making such as sex-selection and genetic enhancement; stem cells, cloning, and abortion; DNA databanks and collection of genetic information; in vitro fertilization and other emerging reproductive technologies.
| Units: 2

HRP 274: Design for Service Innovation (BIOE 372, MED 274)

(Same as OIT 343/01) Open to graduate students from all schools and departments. An experiential project course in which students work in multidisciplinary teams to design new services to address the needs of medically patients. Project teams partner with "safety net" hospitals and clinics to find better ways to deliver care to the low income and uninsured patients these institutions serve. Students learn proven innovation processes from experienced GSB, d. school, and SoM faculty, interface with students from across the university, and have the opportunity to see their ideas translated into improvements in the quality and efficiency of healthcare in the real world. Prerequisite: admission to the course is by application only. Applications available at http://DesignForService.stanford.edu. Applications must be submitted by November 16, 2011.
| Units: 4

HRP 283: Health Services Research Core Seminar

Presentation of research in progress and tutorials in the field of health services research.
| Units: 1 | Repeatable for credit

HRP 296: Current Topics in Bioethics

(Same as LAW 596) Explores the ethical, legal, and public policy issues arising from recent advances in biomedicine and the biosciences. Approaches to bioethical reasoning including casuistry, social justice, resource allocation, and individual rights in areas such as refusal of treatment conception. Topics include: the use of forensic genetics in criminal law, neuroscience and national security, race and ethnicity in genetic research,k experimentation on human subjects and prisoners, privacy of medical and genetic information in the information age, synthetic biology, and do-it-yourself medical and genetic testing. No prior knowledge in science, medicine, philosophy or related disciplines is required.
| Units: 3
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