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ANTHRO 6: Human Origins (ANTHRO 206, BIO 106, HUMBIO 6)

The human fossil record from the first non-human primates in the late Cretaceous or early Paleocene, 80-65 million years ago, to the anatomically modern people in the late Pleistocene, between 100,000 to 50,000 B.C.E. Emphasis is on broad evolutionary trends and the natural selective forces behind them.
| Units: 5 | UG Reqs: GER: DB-NatSci

ANTHRO 14: Introduction to Anthropological Genetics

For upper division undergraduates. The extent and pattern of variation among human genomes, the origin of these patterns in human evolution, and the social and medical impact of recent discoveries. Topics include: the Human Genome Project; human origins; ancient DNA; genetic, behavioral, linguistic, cultural, and racial diversity; the role of disease in shaping genetic diversity; DNA forensics; genes and reproductive technology.
| Units: 3 | UG Reqs: GER: DB-NatSci

ANTHRO 171: The Biology and Evolution of Language (ANTHRO 271, HUMBIO 145L)

Lecture course surveying the biology, linguistic functions, and evolution of the organs of speech and speech centers in the brain, language in animals and humans, the evolution of language itself, and the roles of innateness vs. culture in language. Suitable both for general education and as preparation for further studies in anthropology, biology, linguistics, medicine, psychology, and speech & language therapy. Anthropology concentration: CS, EE. No prerequisites.
Terms: Win | Units: 4-5 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Fox, J. (PI)

ANTHRO 175: Human Skeletal Anatomy (ANTHRO 275, BIO 174, BIO 274, HUMBIO 180)

Study of the human skeleton (a. k. a. human osteology), as it bears on other disciplines, including medicine, forensics, archaeology, and paleoanthropology (human evolution). Basic bone biology, anatomy, and development, emphasizing hands-on examination and identification of human skeletal parts, their implications for determining an individual¿s age, sex, geographic origin, and health status, and for the evolutionary history of our species. Three hours of lecture and at least three hours of supervised and independent study in the lab each week.
Terms: Win | Units: 5 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Klein, R. (PI)

BIO 1: Human Evolution and Environment

Human genetic and cultural evolution and how people interact with their environments, from the ancestors of Australopithecus to current events. Issues include race, gender, and intelligence; pesticide and antibiotic resistance; abortion and contraception; ecosystem services; environmental economics and ethics; the evolution of religion; climate change; population growth and overconsumption; origins and spread of ideas and technologies; and the distribution of political and economic power.
Terms: Spr | Units: 3 | UG Reqs: GER: DB-NatSci

BIO 3N: Views of a Changing Sea: Literature & Science

The state of a changing world ocean, particularly in the eastern Pacific, will be examined through historical and contemporary fiction, non-fiction and scientific publications. Issues will include harvest and mariculture fisheries, land-sea interactions and oceanic climate change in both surface and deep waters.
| Units: 3 | UG Reqs: GER: DB-NatSci

BIO 7S: Introduction to Biology

The major fields of biology: biochemistry, the cell, evolution, and diversity. Foundation for higher-level biology courses.
Terms: Sum | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Li, L. (PI)

BIO 9S: Introduction to Biological Research Methods

Theory and practice of experimental biology. Introduction to how to plan an experiment, conduct, and analyze data. Introduction to scientific writing and reading scientific journal articles. Prerequisite: high school biology.
Last offered: Summer 2011 | Units: 3 | UG Reqs: GER: DB-NatSci

BIO 11N: Biotechnology in Everyday Life

Preference to freshmen. The science that makes transgenic plants and animals possible. Current and future applications of biotechnology and the ethical issues raised.
Terms: Aut | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Walbot, V. (PI)

BIO 15N: Environmental Literacy

Preference to freshmen. Lack of public understanding of the details of most environmental problems is cited as a cause of environmental deterioration. Good citizenship requires literacy about the elements of the scientific and decision making processes that accompany most environmental issues: what can happen, what are the odds, how can the credibility of sources of expertise be assessed, which components of environmental debates deal with factual and theoretical issues, and which are political value judgments?
Terms: Aut | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Root, T. (PI)

BIO 22Q: Infection, Immunity, and Global Health

Why do infectious diseases continue to challenge us despite advances in medicine? This course will explore the causes and prevention of infectious diseases, focusing on the interplay between pathogens, the immune system, the environment, and societal factors that affect disease occurrence and outcomes. Topics will include: basic elements of microbiology, immunology, and epidemiology; case studies of old diseases (e.g., smallpox, tuberculosis, malaria) and recently-emergent diseases (e.g., Ebola, AIDS, antibiotic-resistant bacteria, Lyme disease, and pandemic influenza) that illustrate the biological, environmental, cultural, political, and economic factors that affect disease emergence, spread, and control; the limitations of modern medical approaches such as antibiotics and vaccines; and strategies for reducing global infectious disease threats. The seminar will feature class discussion, student projects, and faculty and student presentations. Prerequisite: biology background, preferably introductory college courses (e.g., 41, 42, or HUMBIO 2A, 3A).
Terms: Spr | Units: 3 | UG Reqs: GER: DB-NatSci
Instructors: ; Jones, P. (PI)

BIO 26N: Maintenance of the Genome

Preference to freshmen. The precious blueprint for life is entrusted to the genomic DNA molecules in all living cells. Multiple strategies have evolved to prevent the deleterious consequences from endogenous DNA alterations and damage from radiation or genotoxic chemicals in the environment. In this seminar you will learn about the remarkable systems that scan cellular DNA for alterations and make repairs to ensure genomic stability. Deficiencies in DNA repair have been implicated in many hereditary diseases involving developmental defects, premature aging, and/or predisposition to cancer. An understanding of DNA repair mechanisms is important for advances in the fields of cancer biology, neurobiology, and gerontology. Background readings, introductory lectures, student presentations, short term paper.
Terms: Aut | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Hanawalt, P. (PI)

BIO 30: Ecology for Everyone (EARTHSYS 30)

Everything is connected, but how? Ecology is the science of interactions and the changes they generate. This project-based course links individual behavior, population growth, species interactions, and ecosystem function. Introduction to measurement, observation, experimental design and hypothesis testing in field projects, mostly done in groups. The goal is to learn to think analytically about everyday ecological processes involving bacteria, fungi, plants, animals and humans. The course uses basic statistics to analyze data; there are no math prerequisites except arithmetic. Open to everyone, including those who may be headed for more advanced courses in ecology and environmental science.
Terms: Spr | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Gordon, D. (PI)

BIO 30N: Extinctions in Near Time: Biodiversity loss since the Pleistocene

The transition 11,700 years ago from the Pleistocene glacial period into the Holocene interglacial witnessed the expansion of humans around the world, climatic warming and the demise of many large vertebrate species. Since that time extinctions have continued on land and in the sea, culminating with the biodiversity crisis we are experiencing today. We will explore these prehistoric extinctions: "Who? When? Where? and Why?" in order to learn more about our planet's future.
Last offered: Autumn 2012 | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-CE, WAY-SMA

BIO 33N: Conservation Science and Practice

Preference to freshmen. Interdisciplinary. The science and art of conservation today. The forces that are driving change in Earth's atmosphere, lands, waters, and variety of life forms. Which broad dimensions of the biosphere, and which elements of ecosystems, most merit protection? The prospects for, and challenges in, making conservation economically attractive and commonplace. Field trip; project.
Last offered: Spring 2012 | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIO 34N: Hunger

The biology of hunger and satiety, disease states that disrupt normal responses to hunger and satiety, starvation responses and adaptations to starvation in a variety of organisms, food production and distribution mechanisms, historic famines and their causes, the challenges of providing adequate food and energy for the Earth's growing population, local and global efforts to alleviate hunger, and hunger in fiction.
Terms: Aut | Units: 3 | UG Reqs: GER: DB-NatSci
Instructors: ; Barton, K. (PI)

BIO 41: Genetics, Biochemistry, and Molecular Biology

Emphasis is on macromolecules (proteins, lipids, carbohydrates, and nucleic acids) and how their structure relates to function and higher order assembly; molecular biology, genome structure and dynamics, gene expression from transcription to translation. Prerequisites: CHEM 31X (or 31A,B), 33. Recommended: CHEM 35; MATH 19, 20, 21 or 41, 42.
Terms: Aut | Units: 5 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIO 41S: Biochemistry, Genetics, and Molecular Biology

Emphasis is on macromolecules (proteins, lipids, carbohydrates, and nucleic acids) and how their structure relates to function and higher order assembly; molecular biology, genome structure and dynamics, gene expression from transcription to translation. Prerequisites: CHEM 31X (or 31A,B), 33; MATH 19, 20, 21 or 41, 42. Recommended: CHEM 35.
Last offered: Summer 2013 | Units: 5 | UG Reqs: GER: DB-NatSci

BIO 42: Cell Biology and Animal Physiology

Cell structure and function; principles of animal physiology (immunology, renal, cardiovascular, sensory, motor physiology, and endocrinology); neurobiology from cellular basis to neural regulation of physiology. Prerequisites: CHEM 31X (or 31A,B), 33. Recommended: BIO 41; CHEM 35; MATH 19, 20, 21 or 41, 42.
Terms: Win | Units: 5 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIO 43: Plant Biology, Evolution, and Ecology

Principles of evolution: macro- and microevolution and population genetics. Ecology: the principles underlying the exchanges of mass and energy between organisms and their environments; population, community, and ecosystem ecology; populations, evolution, and global change. Equivalent to BIOHOPK 43. Prerequisites: CHEM 31X (or 31A,B), 33. Recommended: BIO 41, 42; CHEM 35; MATH 19, 20, 21 or 41, 42.
Terms: Spr | Units: 5 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIO 101: Ecology

The principles of ecology. Topics: interactions of organisms with their environment, dynamics of populations, species interactions, structure and dynamics of ecological communities, biodiversity. Half-day field trip required. Satisfies Central Menu Area 4. Prerequisite: 43, or consent of instructor. Recommended: statistics.
Terms: Aut | Units: 4 | UG Reqs: GER: DB-NatSci
Instructors: ; Peay, K. (PI)

BIO 104: Advanced Molecular Biology (BIO 200)

Molecular mechanisms that govern the replication, recombination, and expression of eukaryotic genomes. Topics: DNA replication, DNA recombination, gene transcription, RNA splicing, regulation of gene expression, protein synthesis, and protein folding. Satisfies Central Menu Area 1. Prerequisite: Biology core.
Terms: Win | Units: 5 | UG Reqs: GER: DB-NatSci

BIO 109A: The Human Genome and Disease (BIO 209A, BIOC 109A, BIOC 209A, HUMBIO 158)

The variability of the human genome and the role of genomic information in research, drug discovery, and human health. Concepts and interpretations of genomic markers in medical research and real life applications. Human genomes in diverse populations. Original contributions from thought leaders in academia and industry and interaction between students and guest lecturers. Students with a major, minor or coterm in Biology: 109A/209A or 109B/209B may count toward degree program but not both.
Terms: Win | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIO 109B: The Human Genome and Disease: Genetic Diversity and Personalized Medicine (BIO 209B, BIOC 109B, BIOC 209B)

Continuation of 109A/209A. Genetic drift: the path of human predecessors out of Africa to Europe and then either through Asia to Australia or through northern Russia to Alaska down to the W. Coast of the Americas. Support for this idea through the histocompatibility genes and genetic sequences that predispose people to diseases. Guest lectures from academia and pharmaceutical companies. Prerequisite: Biology or Human Biology core. Students with a major, minor or coterm in Biology: 109A/209A or 109B/209B may count toward degree program but not both.
Terms: Spr | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIO 110: DNA Replication and Genomic Maintenance (BIO 210)

Maintenance of the genome and its accurate replication are prerequisites for life. DNA replication is also intricately connected to pathways for responding to genotoxic stress, which include inevitable collisions with transcription. In eukaryotes, DNA repair and replication are tightly connected to chromatin modification. Emphasis for lecture topics include: DNA-templated chromatin transactions; Chromatin manipulation during replication and DNA damage responses; Structural biology and molecular mechanisms of replication and DNA repair enzymes; Inducible responses to genotoxic stress; Relationships of DNA damage processing to mutagenesis, carcinogenesis, aging and human genetic disease.
Terms: Spr | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIO 112: Human Physiology (BIO 212, HUMBIO 133)

Human physiology will be examined by organ systems: respiratory, cardiovascular, renal, and gastrointestinal. Concepts of cell and molecular biology that underlie organ development, pathophysiology and opportunities for regenerative medicine will be introduced. Signaling and integrative control by the endocrine, autonomic and central nervous systems will be introduced. Prerequisite: Biology or Human Biology core.
Terms: Win | Units: 4 | UG Reqs: GER: DB-NatSci
Instructors: ; Kao, P. (PI)

BIO 113: Fundamentals of Molecular Evolution (BIO 244)

The inference of key molecular evolutionary processes from DNA and protein sequences. Topics include random genetic drift, coalescent models, effects and tests of natural selection, combined effects of linkage and natural selection, codon bias and genome evolution. Satisfies Central Menu Areas 1 or 4. Prerequisites: Biology core or graduate standing in any department, and consent of instructor.
Terms: Win | Units: 4 | UG Reqs: GER: DB-NatSci

BIO 116: Ecology of the Hawaiian Islands (EARTHSYS 116)

Terrestrial and marine ecology and conservation biology of the Hawaiian Archipelago. Taught in the field in Hawaii as part of quarter-long sequence of courses including Earth Sciences and Anthropology. Topics include ecological succession, plant-soil interactions, conservation biology, biological invasions and ecosystem consequences, and coral reef ecology. Restricted to students accepted into the Earth Systems of Hawaii Program.
Last offered: Autumn 2012 | Units: 4 | UG Reqs: GER: DB-NatSci

BIO 117: Biology and Global Change (EARTHSYS 111, EESS 111)

The biological causes and consequences of anthropogenic and natural changes in the atmosphere, oceans, and terrestrial and freshwater ecosystems. Topics: glacial cycles and marine circulation, greenhouse gases and climate change, tropical deforestation and species extinctions, and human population growth and resource use. Prerequisite: Biology or Human Biology core or graduate standing.
Terms: Win | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIO 118: Genetic Analysis of Biological Processes (BIO 218)

Genetic principles and their experimental applications. Emphasis is on the identification and use of mutations to study cellular function. Satisfies Central Menu Areas 1 or 2. Prerequisite: Biology core.
Terms: Win | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIO 121: Biogeography

Global distributions of organisms through the Phanerozoic, with emphasis on historical causes. Topics: plate tectonics, island biogeography, climatic change, dispersal, vicariance, ecology of invasions, extinction, gradients, diversity. Satisfies Central Menu Area 4.
Last offered: Spring 2009 | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIO 129A: Cellular Dynamics I: Cell Motility and Adhesion

Cell motility emphasizing role of actin assembly and dynamics coupling actin organization to cell movement. Interaction of cells with extracellular matrix, and remodelling of extracellular matrix in development and disease. Directed cell migration by chemotaxis (neuronal path-finding, immune cells). Cell-cell adhesion, formation of intercellular junctions and mechanisms regulating cell-cell interactions in development and diseases. Emphasis is on experimental logic, methods, problem solving, and interpretation of results. Students present research papers. Satisfies Central Menu Area 2. Prerequisite: Biology core.
Terms: Win | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-AQR, WAY-SMA
Instructors: ; Nelson, W. (PI)

BIO 129B: Cellular Dynamics II: Building a Cell

Principles of cell organization; how common biochemical pathways are modified to generate diversity in cell structure and function. Roles of actin and microtubule cytoskeletons in cellular architecture. Mechanisms of protein sorting and trafficking, and protein modules and switches in regulating cell polarity. Yeast to polarized epithelial cells and neurons. Emphasis is on experimental logic, methods, problem solving, and interpretation of results. Students present research papers. Satisfies Central Menu Area 2. Prerequisite: Biology core. Recommended: 129A.
Terms: Spr | Units: 4 | UG Reqs: GER: DB-NatSci
Instructors: ; Nelson, W. (PI)

BIO 132: Advanced Imaging Lab in Biophysics (APPPHYS 232, BIO 232, BIOPHYS 232, GENE 232)

Laboratory and lectures. Advanced microscopy and imaging, emphasizing hands-on experience with state-of-the-art techniques. Students construct and operate working apparatus. Topics include microscope optics, Koehler illumination, contrast-generating mechanisms (bright/dark field, fluorescence, phase contrast, differential interference contrast), and resolution limits. Laboratory topics vary by year, but include single-molecule fluorescence, fluorescence resonance energy transfer, confocal microscopy, two-photon microscopy, and optical trapping. Limited enrollment. Recommended: basic physics, Biology core or equivalent, and consent of instructor.
Terms: Spr | Units: 4 | UG Reqs: GER: DB-NatSci

BIO 136: Evolutionary Paleobiology

A paleontological approach to evolutionary theory. Topics: history of life, speciation, heterochrony, evolutionary constraint, coevolution, macroevolution, the Cambrian Explosion, mass extinctions, taphonomy, life on land, life in the sea, life in the air. Satisfies Central Menu Area 4. Prerequisite: Biology Core.
Last offered: Winter 2011 | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIO 137: Plant Genetics (BIO 237)

Gene analysis, mutagenesis, transposable elements; developmental genetics of flowering and embryo development; biochemical genetics of plant metabolism; scientific and societal lessons from transgenic plants. Satisfies Central Menu Area 2. Prerequisite: Biology core or consent of instructor. Satisfies WIM in Biology.
Terms: Spr | Units: 3-4 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Walbot, V. (PI)

BIO 139: Biology of Birds

How birds interact with their environments and each other, emphasizing studies that had impact in the fields of population biology, community ecology, and evolution. Local bird communities. Emphasis is on field research. Enrollment limited to 20. Prerequisites: 43 or equivalent, and consent of instructor. Recommended: birding experience.
Last offered: Spring 2013 | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIO 13N: Environmental Problems and Solutions

Preference to freshmen. Students do independent investigations of current environmental problems, analyzing differing views of them and discussing possible solutions. Each student gives seminar presentations and leads seminar discussions. Short, documented position papers are written for policy makers.
| Units: 3 | UG Reqs: GER: DB-NatSci

BIO 144: Conservation Biology: A Latin American Perspective (BIO 234, HUMBIO 112)

Principles and application of the science of preserving biological diversity. Conceptually, this course is designed to explore 4 major components relevant to the conservation of biodiversity, as exemplified by the Latin American region. The conceptual frameworks and principles, however, should be generally applicable, and provide insights for all regions of the world, including those of lesser biodiversity. Satisfies Central Menu Area 4 for Bio majors. Prerequisite: BIO 101, or BIO 43 or HUMBIO 2A with consent of instructor. Graduate level students will be expected to conduct a literature research exercise leading to a written paper, addressing a topic of their choosing, derived from any of the themes discussed in class.
Terms: Spr | Units: 3 | UG Reqs: GER: DB-NatSci
Instructors: ; Dirzo, R. (PI)

BIO 149: The Neurobiology of Sleep (BIO 249, HUMBIO 161)

Preference to seniors and graduate students. The neurochemistry and neurophysiology of changes in brain activity and conscious awareness associated with changes in the sleep/wake state. Behavioral and neurobiological phenomena including sleep regulation, sleep homeostasis, circadian rhythms, sleep disorders, sleep function, and the molecular biology of sleep. Enrollment limited to 16.
Last offered: Winter 2013 | Units: 4 | UG Reqs: GER: DB-NatSci

BIO 150: Human Behavioral Biology (BIO 250, HUMBIO 160)

Multidisciplinary. How to approach complex normal and abnormal behaviors through biology. How to integrate disciplines including sociobiology, ethology, neuroscience, and endocrinology to examine behaviors such as aggression, sexual behavior, language use, and mental illness.
Terms: Spr | Units: 5 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIO 151: Mechanisms of Neuron Death

For Biology majors with background in neuroscience. Cell and molecular biology of neuron death during neurological disease. Topics: the amyloid diseases (Alzheimer's), prion diseases (kuru and Creutzfeldt-Jakob), oxygen radical diseases (Parkinson's and ALS), triplet repeat diseases (Huntington's), and AIDS-related dementia. Student presentations. Enrollment limited to 15; application required.
Terms: Aut | Units: 3 | UG Reqs: GER: DB-NatSci
Instructors: ; Sapolsky, R. (PI)

BIO 153: Cellular Neuroscience: Cell Signaling and Behavior (PSYCH 120)

Neural interactions underlying behavior. Prerequisites: PSYCH 1 or basic biology.
Terms: Aut | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIO 154: Molecular and Cellular Neurobiology

For advanced undergraduate students. Cellular and molecular mechanisms in the organization and functions of the nervous system. Topics: wiring of the neuronal circuit, synapse structure and synaptic transmission, signal transduction in the nervous system, sensory systems, molecular basis of behavior including learning and memory, molecular pathogenesis of neurological diseases. Satisfies Central Menu Areas 2 or 3 for Bio majors. Prerequisite for undergraduates: Biology core or equivalent, or consent of instructors.
| Units: 4 | UG Reqs: GER: DB-NatSci

BIO 157: Biochemistry and Molecular Biology of Plants (BIO 257)

Biochemical and molecular basis of plant growth and adaptation. Topics include: hormone signal transduction; photoreceptor chemistry and signaling; metabolite sensing and transport; dynamics of photosynthesis; plant innate immunity and symbiosis. Lectures and readings will emphasize research methods. Prerequisite: Biology core or equivalent, or consent of instructor.
Terms: Spr | Units: 3-4 | UG Reqs: GER: DB-NatSci

BIO 158: Developmental Neurobiology (BIO 258)

For advanced undergraduates and coterminal students. The principles of nervous system development from the molecular control of patterning, cell-cell interactions, and trophic factors to the level of neural systems and the role of experience in influencing brain structure and function. Topics: neural induction and patterning cell lineage, neurogenesis, neuronal migration, axonal pathfinding, synapse elimination, the role of activity, critical periods, and the development of behavior. Satisfies Central Menu Areas 2 or 3. Prerequisite: BIO 42 or equivalent.
Last offered: Spring 2013 | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIO 160A: Developmental Biology I

Focus is on the molecular mechanisms underlying the generation of diverse cell types and tissues during embryonic and post-embryonic animal development. The role of cell-cell communication in controlling key developmental decisions. Topics covered in this quarter include embryonic axis formation, morphogen signaling, cell type specification and stem cells. Experimental logic and methods of research in developmental biology. Discussions of research papers. Satisfies Central Menu Areas 1 or 2. Prerequisite: Biology core or consent of instructor.
Terms: Aut | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Simon, M. (PI)

BIO 160B: Developmental Biology II

Continuation of BIO 160A. Focus is on the molecular mechanisms underlying the generation of diverse cell types and tissues during embryonic and post-embryonic animal development. The role of cell-cell communication in controlling key developmental decisions. The topics include sexual control of development, tissue polarity and growth, cell migration, regeneration, and the evolution of developmental mechanisms. Experimental logic and methods of research in developmental biology. Discussions of research papers. Satisfies Central Menu Areas 1 or 2. Prerequisites: Biology Core and 160A, or consent of instructor.
Terms: Win | Units: 4 | UG Reqs: GER: DB-NatSci
Instructors: ; Simon, M. (PI)

BIO 174: Human Skeletal Anatomy (ANTHRO 175, ANTHRO 275, BIO 274, HUMBIO 180)

Study of the human skeleton (a. k. a. human osteology), as it bears on other disciplines, including medicine, forensics, archaeology, and paleoanthropology (human evolution). Basic bone biology, anatomy, and development, emphasizing hands-on examination and identification of human skeletal parts, their implications for determining an individual¿s age, sex, geographic origin, and health status, and for the evolutionary history of our species. Three hours of lecture and at least three hours of supervised and independent study in the lab each week.
Terms: Win | Units: 5 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Klein, R. (PI)

BIO 188: Biochemistry I (BIO 288, CHEM 181, CHEMENG 181, CHEMENG 281)

(CHEMENG offerings formerly listed as 188/288.) Chemistry of major families of biomolecules including proteins, nucleic acids, carbohydrates, lipids, and cofactors. Structural and mechanistic analysis of properties of proteins including molecular recognition, catalysis, signal transduction, membrane transport, and harvesting of energy from light. Molecular evolution. Satisfies Central Menu Area 1 for Bio majors. Prerequisites: CHEM 33, 35, 131, and 135 or 171.
Terms: Aut | Units: 3 | UG Reqs: GER: DB-NatSci

BIO 189: Biochemistry II (BIO 289, CHEM 183, CHEMENG 183, CHEMENG 283)

Focus on metabolic biochemistry: the study of chemical reactions that provide the cell with the energy and raw materials necessary for life. Topics include glycolysis, gluconeogenesis, the citric acid cycle, oxidative phosphorylation, photosynthesis, the pentose phosphate pathway, and the metabolism of glycogen, fatty acids, amino acids, and nucleotides as well as the macromolecular machines that synthesize RNA, DNA, and proteins. Medical relevance is emphasized throughout. Satisfies Central Menu Area 1 for Bio majors. Prerequisite: BIO 188/288 or CHEM 181 or CHEMENG 181/281 (formerly 188/288).
Terms: Win | Units: 3 | UG Reqs: GER: DB-NatSci
Instructors: ; Dunn, A. (PI)

BIO 20: Introduction to Brain and Behavior (HUMBIO 21)

Evolutionary principles to understand how the brain regulates behavior physiologically, and is also influenced by behavioral interactions. Topics include neuron structure and function, transmission of neural information, anatomy and physiology of sensory and motor systems, regulation of body states, the biological basis of learning and memory, and behavioral abnormalities.
| Units: 3 | UG Reqs: GER: DB-NatSci

BIO 23N: FACEBUG: The Social Life of Microbes

Exploration of three crucial aspects of microbial life. First, examine how the unseen microbial majority is responsible for critical but under-appreciated aspects of the biology of the planet. Second, investigate the array of current genomic and imaging tools available to probe microscopic organisms in the environment. Last, we will research the importance of microbial communities and social dynamics in ecological and human health settings.
| Units: 3 | UG Reqs: GER: DB-NatSci

BIO 37N: Green Revolution and Plant Biotechnology

Feeding ever-growing populations is a constant challenge to mankind. In the second half of the 20th century, the breeding of improved varieties combined with the use of chemical fertilizers and pesticides led to crop yield increases labeled the Green Revolution. Modern technologies in genetic engineering are expected to bring the second green revolution. Meeting the current and future global food needs without further damaging the fragile environment requires innovative effort from scientists and the society.
| Units: 3 | UG Reqs: GER: DB-NatSci

BIO 106: Human Origins (ANTHRO 6, ANTHRO 206, HUMBIO 6)

The human fossil record from the first non-human primates in the late Cretaceous or early Paleocene, 80-65 million years ago, to the anatomically modern people in the late Pleistocene, between 100,000 to 50,000 B.C.E. Emphasis is on broad evolutionary trends and the natural selective forces behind them.
| Units: 5 | UG Reqs: GER: DB-NatSci

BIO 143: Evolution

The basic facts and principles of the evolution of all life. The logic of and evidence for the correctness of Darwin's argument for evolution by natural selection. How Mendelian genetics was integrated into evolutionary thinking. The integration of physiological and ecological perspectives into the study of evolutionary adaptation within species. Species formation and evolutionary divergence among species. Patterns of evolution over long time scales. Satisfies Central Menu Area 4.
| Units: 3 | UG Reqs: GER: DB-NatSci

BIO 145: Behavioral Ecology (BIO 245)

Animal behavior from an evolutionary and ecological perspective. Topics: foraging, territoriality, reproductive behavior, social groups. Lecture/seminar format; seminars include discussion of journal articles. Independent research projects. Satisfies Central Menu Area 4 for Bio majors. Prerequisites: Biology or Human Biology core, or consent of instructor. Recommended: statistics. Satisfies WIM in Biology.
| Units: 4 | UG Reqs: GER: DB-NatSci

BIO 152: Imaging: Biological Light Microscopy (MCP 222)

Survey of instruments which use light and other radiation for analysis of cells in biological and medical research. Topics: basic light microscopy through confocal fluorescence and video/digital image processing. Lectures on physical principles; involves partial assembly and extensive use of lab instruments. Lab. Prerequisites: some college physics, Biology core.
| Units: 3 | UG Reqs: GER: DB-NatSci

BIO 163: Neural Systems and Behavior (BIO 263, HUMBIO 163)

The field of neuroethology and its vertebrate and invertebrate model systems. Research-oriented. Readings include reviews and original papers. How animal brains compare; how neural circuits are adapted to species-typical behavior; and how the sensory worlds of different species represent the world. Lectures and required discussions. Satisfies Central Menu Area 3 for Bio majors. Prerequisites: BIO 42, HUMBIO 4A.
| Units: 4 | UG Reqs: GER: DB-NatSci

BIO 164: Biosphere-Atmosphere Interactions (BIO 264)

Physiological, ecological, and physical aspects of ecosystem function, emphasizing how ecosystems influence and are influenced by the atmosphere. Prerequisites: 42, 43; or consent of instructor.
| Units: 4 | UG Reqs: GER: DB-NatSci

BIO 171: Principles of Cell Cycle Control (BIO 271, CSB 271)

Genetic analysis of the key regulatory circuits governing the control of cell division. Illustration of key principles that can be generalized to other synthetic and natural biological circuits. Focus on tractable model organisms; growth control; irreversible biochemical switches; chromosome duplication; mitosis; DNA damage checkpoints; MAPK pathway-cell cycle interface; oncogenesis. Analysis of classic and current primary literature. Satisfies Central Menu Area 2.
| Units: 3 | UG Reqs: GER: DB-NatSci

BIO 175: Tropical Ecology and Conservation

Spring Break trip to a field station; lectures at Stanford. How to address scientific questions concerning ecology and conservation. Field trip includes natural history observations and group research projects. Symposium based on project results.
| Units: 5 | UG Reqs: GER: DB-NatSci

BIO 271: Principles of Cell Cycle Control (BIO 171, CSB 271)

Genetic analysis of the key regulatory circuits governing the control of cell division. Illustration of key principles that can be generalized to other synthetic and natural biological circuits. Focus on tractable model organisms; growth control; irreversible biochemical switches; chromosome duplication; mitosis; DNA damage checkpoints; MAPK pathway-cell cycle interface; oncogenesis. Analysis of classic and current primary literature. Satisfies Central Menu Area 2.
| Units: 3 | UG Reqs: GER: DB-NatSci

BIOC 109A: The Human Genome and Disease (BIO 109A, BIO 209A, BIOC 209A, HUMBIO 158)

The variability of the human genome and the role of genomic information in research, drug discovery, and human health. Concepts and interpretations of genomic markers in medical research and real life applications. Human genomes in diverse populations. Original contributions from thought leaders in academia and industry and interaction between students and guest lecturers. Students with a major, minor or coterm in Biology: 109A/209A or 109B/209B may count toward degree program but not both.
Terms: Win | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIOC 109B: The Human Genome and Disease: Genetic Diversity and Personalized Medicine (BIO 109B, BIO 209B, BIOC 209B)

Continuation of 109A/209A. Genetic drift: the path of human predecessors out of Africa to Europe and then either through Asia to Australia or through northern Russia to Alaska down to the W. Coast of the Americas. Support for this idea through the histocompatibility genes and genetic sequences that predispose people to diseases. Guest lectures from academia and pharmaceutical companies. Prerequisite: Biology or Human Biology core. Students with a major, minor or coterm in Biology: 109A/209A or 109B/209B may count toward degree program but not both.
Terms: Spr | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIOC 118Q: Genomics and Medicine

Preference to sophomores. Knowledge gained from sequencing human genomes and implications for medicine and biomedical research. Novel diagnoses and treatment of diseases, including stem cells, gene therapy and rational drug design. Personal genomics and how it is used to improve health and well being. Social and ethical implications of genetic information such as privacy, discrimination and insurability. Course Webpage: http://biochem118.stanford.edu/.
Terms: Aut | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Brutlag, D. (PI)

BIOC 158: Genomics, Bioinformatics and Medicine (BIOC 258, BIOMEDIN 258, HUMBIO 158G)

Molecular basis of inherited human disease. Diagnostics approaches: simple Mendelian diseases and complex, multifactorial diseases. Genomics: functional genomics, epigenetics, gene expression, SNPs, copy number and other structural genomic variations involved in disease. Novel therapeutic methods: stem cell therapy, gene therapy and drug developments that depend on the knowledge of genomics. Personal genomics, pharmacogenomics, clinical genomics and their role in the future of preventive medicine. Prerequisites: BIO 41 or HUMBIO 2A or consent of instructor. Those with credit in BIOC 118 not eligible to enroll. Course webpage: http://biochem158.stanford.edu/
Terms: Aut, Win, Spr | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA | Repeatable 2 times (up to 6 units total)
Instructors: ; Brutlag, D. (PI)

BIOHOPK 43: Plant Biology, Evolution, and Ecology

Introduction to biology in a marine context. Principles of plant biology: physiology, structure, diversity. Principles of evolution: macro and microevolution, population genetics. Ecology: the principles governing the distribution and abundance of organisms; population, community, and ecosystem ecology. Equivalent to BIO 43. Corequisite: BIOHOPK 44Y.
Terms: Spr | Units: 5 | UG Reqs: GER: DB-NatSci

BIOHOPK 44Y: Core Laboratory in Plant Biology, Ecology and Evolution

Laboratory and field projects provide working familiarity with the concepts, organisms, and techniques of plant and evolutionary biology, and ecology. Emphasis is on hands-on experimentation in the marine environment, analysis of data, and written and oral presentation of the experiments. Equivalent to BIO 44Y. Corequisite: BIOHOPK 43. Satisfies WIM in Biology.
Terms: Spr | Units: 5 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIOHOPK 161H: Invertebrate Zoology (BIOHOPK 261H)

(Graduate students register for 261H.) Survey of invertebrate diversity emphasizing form and function in a phylogenetic framework. Morphological diversity, life histories, physiology, and ecology of the major invertebrate groups, concentrating on local marine forms as examples. Current views on the phylogenetic relationships and evolution of the invertebrates. Lectures, lab, plus field trips. Satisfies Central Menu Area 3 for Bio majors. Prerequisite: Biology core or consent of instructor.
Terms: Win | Units: 5 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Watanabe, J. (PI)

BIOHOPK 162H: Comparative Animal Physiology (BIOHOPK 262H)

(Graduate students register for 262H.) How animals work. Topics: physiology of respiration, circulation, energy metabolism, thermal regulation, osmotic regulation, muscle physiology, and locomotion. Evolutionary and ecological physiology. Lectures, lab, and field research. An option to combine the course work with a more intensive research focus, with more units, is available. Satisfies Central Menu Area 3 for Bio majors. Prerequisite: Biology core or consent of instructor.
Last offered: Spring 2012 | Units: 5 | UG Reqs: GER: DB-NatSci

BIOHOPK 163H: Oceanic Biology (BIOHOPK 263H)

(Graduate students register for 263H.) How the physics and chemistry of the oceanic environment affect marine plants and animals. Topics: seawater and ocean circulation, separation of light and nutrients in the two-layered ocean, oceanic food webs and trophic interactions, oceanic environments, biogeography, and global change. Lectures, discussion, and field trips. Satisfies Central Menu Area 4 for Bio majors. Recommended: PHYSICS 21 or 51, CHEM 31, Biology core, or consent of instructor.
Terms: Win | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIOHOPK 166H: Molecular Ecology (BIOHOPK 266H)

(Graduate students register for 266H.) How modern technologies in gene sequencing, detection of nuclear nucleotide polymorphisms, and other approaches are used to gather data on genetic variation that allow measurement of population structure, infer demographic histories, inform conservation efforts, and advance understanding of the ecology of diverse types of organisms.
Terms: Win | Units: 5 | UG Reqs: GER: DB-NatSci
Instructors: ; Palumbi, S. (PI)

BIOHOPK 172H: Marine Ecology (BIOHOPK 272H)

(Graduate students register for 272H.) Course provides key concepts in ecology , familiarizes students with local marine ecosystems, the methods used in ecological studies of these ecosystems, and the analysis and interpretation of ecological data. Students will engage in presentation and debates of current topics in marine ecology and conservation. Satisfies Central Menu Area 4 for Bio majors. Prerequisite: Biology core or consent of instructor.
Terms: Win | Units: 5 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Micheli, F. (PI)

BIOHOPK 174H: Experimental Design and Probability (BIOHOPK 274H)

(Graduate students register for 274H.) Variability is an integral part of biology. Introduction to probability and its use in designing experiments to address biological problems. Focus is on analysis of variance, when and how to use it, why it works, and how to interpret the results. Design of complex, but practical, asymmetrical experiments and environmental impact studies, and regression and analysis of covariance. Computer-based data analysis. Prerequisite: Biology core or consent of instructor.
Terms: Spr | Units: 3 | UG Reqs: GER: DB-NatSci, GER:DB-Math, WAY-AQR, WAY-FR
Instructors: ; Watanabe, J. (PI)

BIOHOPK 182H: Stanford at Sea (BIOHOPK 323H, EARTHSYS 323, EESS 323)

(Graduate students register for 323H.) Five weeks of marine science including oceanography, marine physiology, policy, maritime studies, conservation, and nautical science at Hopkins Marine Station, followed by five weeks at sea aboard a sailing research vessel in the Pacific Ocean. Shore component comprised of three multidisciplinary courses meeting daily and continuing aboard ship. Students develop an independent research project plan while ashore, and carry out the research at sea. In collaboration with the Sea Education Association of Woods Hole, MA. Only 6 units may count towards the Biology major.
Last offered: Spring 2013 | Units: 16 | UG Reqs: GER: DB-NatSci, WAY-SMA

BIOHOPK 167H: Nerve, Muscle, and Synapse (BIOHOPK 267H)

(Graduate students register for 267H.) Fundamental aspects of membrane excitability, nerve conduction, synaptic transmission, and excitation-contraction coupling. Emphasis is on biophysical, molecular, and cellular level analyses of these processes in vertebrate and invertebrate systems. Labs on intra- and extracellular recording and patch clamp techniques. Lectures, discussions, and labs. Satisfies Central Menu Area 3 for Bio majors Prerequisites: PHYSICS 23, 28, 43, or equivalent; CHEM 31, 135; calculus; or consent of instructor.
| Units: 5 | UG Reqs: GER: DB-NatSci

BIOHOPK 184H: Holistic Biology (BIOHOPK 284H)

(Graduate students register for 284H.) For majors and non-majors. Complexity in natural systems is examined from complementary points of view, including scientific, historical, philosophical and literary. Lectures and discussions will focus on the writings of Ed Ricketts and John Steinbeck, poetry of Robinson Jeffers and on historical and contemporary works concerning marine and fresh-water systems, resource management and climate change. A group project with individual contributions will be carried out and presented at a symposium. This course will involve a significant amount of creative writing, and it satisfies the Writing in Major requirement for Biology. It is open to all majors and classes. Only 6 units may count towards the Biology major.
| Units: 16 | UG Reqs: GER: DB-NatSci

CEE 63: Weather and Storms (CEE 263C)

Daily and severe weather and global climate. Topics: structure and composition of the atmosphere, fog and cloud formation, rainfall, local winds, wind energy, global circulation, jet streams, high and low pressure systems, inversions, el Niño, la Niña, atmosphere/ocean interactions, fronts, cyclones, thunderstorms, lightning, tornadoes, hurricanes, pollutant transport, global climate and atmospheric optics.
Terms: Aut | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Jacobson, M. (PI)

CEE 64: Air Pollution and Global Warming: History, Science, and Solutions (CEE 263D)

Survey of Survey of air pollution and global warming and their renewable energy solutions. Topics: evolution of the Earth's atmosphere, history of discovery of chemicals in the air, bases and particles in urban smog, visibility, indoor air pollution, acid rain, stratospheric and Antarctic ozone loss, the historic climate record, causes and effects of global warming, impacts of energy systems on pollution and climate, renewable energy solutions to air pollution and global warming. UG Reqs: GER: DBNatSci
Terms: Win | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA

CEE 164: Introduction to Physical Oceanography (CEE 262D, EARTHSYS 164, EESS 148)

The dynamic basis of oceanography. Topics: physical environment; conservation equations for salt, heat, and momentum; geostrophic flows; wind-driven flows; the Gulf Stream; equatorial dynamics and ENSO; thermohaline circulation of the deep oceans; and tides. Prerequisite: PHYSICS 41 (formerly 53).
Terms: Win | Units: 4 | UG Reqs: GER: DB-NatSci

CEE 196: Engineering Geology and Global Change (GES 115)

The application of geology and global change to the planning, design, and operation of engineering projects. Case histories taught in a seminar setting and field trips emphasize the impact of geology and global change on both individual engineering works and the built environment by considering Quaternary history and tectonics, anthropogenic sea level rise, active geologic processes, engineering properties of geologic deposits, site exploration, and professional ethics. Prerequisite: GES 1 or consent of instructor.
| Units: 3 | UG Reqs: GER: DB-NatSci
Instructors: ; Holzer, T. (PI)

CHEM 26N: The What, Why, How and wow's of Nanotechnology

Preference to freshmen. Introduction to nanotechnology with discussion of basic science at the nanoscale, its difference from molecular and macroscopic scales, and implications and applications. Developments in nanotechnology in the past two decades, from imaging and moving single atoms on surfaces to killing cancer cells with nanoscale tools and gadgets.
Terms: Spr | Units: 3 | UG Reqs: GER: DB-NatSci
Instructors: ; Dai, H. (PI)

CHEM 31A: Chemical Principles I

For students with moderate or no background in chemistry. Stoichiometry; periodicity; electronic structure and bonding; gases; enthalpy; phase behavior. Emphasis is on skills to address structural and quantitative chemical questions; lab provides practice. Recitation.
Terms: Aut, Sum | Units: 5 | UG Reqs: GER: DB-NatSci, WAY-SMA

CHEM 31B: Chemical Principles II

Chemical equilibrium; acids and bases; oxidation and reduction reactions; chemical thermodynamics; kinetics. Lab. Prerequisite: 31A.
Terms: Win, Sum | Units: 5 | UG Reqs: GER: DB-NatSci, WAY-SMA

CHEM 31X: Chemical Principles

Accelerated; for students with substantial chemistry background. Chemical equilibria concepts, equilibrium constants, acids and bases, chemical thermodynamics, quantum concepts, models of ionic and covalent bonding, atomic and molecular orbital theory, periodicity, and bonding properties of matter. Recitation. Prerequisites for Autumn Quarter only: AP chemistry score of 5 or passing score on chemistry placement test. No Summer Quarter prerequisites. Recommended: high school physics.
Terms: Aut | Units: 5 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Cox, C. (PI); Zare, R. (PI)

CHEM 33: Structure and Reactivity

Organic chemistry, functional groups, hydrocarbons, stereochemistry, thermochemistry, kinetics, chemical equilibria. Recitation. Prerequisite: 31A,B, or 31X, or an AP Chemistry score of 5.
Terms: Win, Spr | Units: 5 | UG Reqs: GER: DB-NatSci, WAY-SMA

CHEM 35: Organic Monofunctional Compounds

Structure and reactivity of polysubstituted chemical compounds containing oxygen and nitrogen functional groups. Recitation. Prerequisite: Chem 33
Terms: Aut, Spr | Units: 4 | UG Reqs: GER: DB-NatSci

CHEM 36: Organic Chemistry Laboratory I

Techniques for separations of compounds: distillation, crystallization, extraction, and chromatographic procedures. Lecture treats theory; lab provides practice. Prerequisite: prerequisite or corequisite CHEM 35
Terms: Aut, Spr | Units: 3 | UG Reqs: GER: DB-NatSci

CHEM 130: Organic Chemistry Laboratory II

Diels-Alder, reduction, and Wittig reactions; qualitative analysis. Lab. Limited enrollment Autumn Quarter. Prerequisite: 35 and 36. Corequisite: 131.
Terms: Aut, Win | Units: 3 | UG Reqs: GER: DB-NatSci
Instructors: ; Vollmer-Snarr, H. (PI)

CHEM 131: Organic Polyfunctional Compounds

Aromatic compounds, polysaccharides, amino acids, proteins, natural products, dyes, purines, pyrimidines, nucleic acids, and polymers. Prerequisite: 35.
Terms: Aut, Win | Units: 3 | UG Reqs: GER: DB-NatSci

CHEM 132: Synthesis Laboratory

Advanced synthetic methods in organic and inorganic laboratory chemistry. Prerequisites: 35, 130.
Terms: Win | Units: 3 | UG Reqs: GER: DB-NatSci
Instructors: ; Cox, C. (PI)

CHEM 134: Analytical Chemistry Laboratory

Methods include gravimetric, volumetric, spectrophotometric, and chromatographic. Writing instruction includes communications, full papers, research proposals, and referee papers. Lab. Prerequisite: 130.
Terms: Spr | Units: 5 | UG Reqs: GER: DB-NatSci, WAY-AQR, WAY-SMA
Instructors: ; Cox, C. (PI); Zare, R. (PI)

CHEM 135: Physical Chemical Principles

Introductory physical chemistry intended for students of the life sciences, geology and environmental engineering. Chemical kinetics: rate laws, integration of rate laws, reaction mechanisms, enzyme kinetics. Chemical thermodynamics: first, second and third laws, thermochemistry, entropy, free energy, chemical equilibrium, physical equilibrium, osmotic pressure, other colligative properties. Prerequisites: 31A,B, or 31X, calculus.
Terms: Win | Units: 3 | UG Reqs: GER: DB-NatSci

CHEM 137: Special Topics in Synthesis

The course covers the basic toolbox for construction of more complex structures for function, largely directed towards molecules of biological relevance. The focus will be the ability to perform structural changes efficiently in order to enable the design of the best structure for a function. The inter-relationship of synthetic chemistry and pharmaceuticals is emphasized. Prerequisite CHEM 35.
Terms: Spr | Units: 3 | UG Reqs: GER: DB-NatSci
Instructors: ; Trost, B. (PI)

CHEM 151: Inorganic Chemistry I

Theories of electronic structure, stereochemistry, and symmetry properties of inorganic molecules. Topics: ionic and covalent interactions, electron-deficient bonding, and molecular orbital theories. Emphasis is on the chemistry of the metallic elements. Prerequisites: 35. Recommended: 171.
Terms: Win | Units: 3 | UG Reqs: GER: DB-NatSci
Instructors: ; Stack, D. (PI)

CHEM 153: Inorganic Chemistry II

The theoretical aspects of inorganic chemistry. Group theory; many-electron atomic theory; molecular orbital theory emphasizing general concepts and group theory; ligand field theory; application of physical methods to predict the geometry, magnetism, and electronic spectra of transition metal complexes. Prerequisites: 151, 173.
Terms: Spr | Units: 3 | UG Reqs: GER: DB-NatSci
Instructors: ; Solomon, E. (PI)

CHEM 171: Physical Chemistry

Chemical thermodynamics; fundamental principles, Gibbsian equations, systematic deduction of equations, equilibrium conditions, phase rule, gases, solutions. Prerequisites: 31A,B, or 31X, 35; MATH 51.
Terms: Spr | Units: 3 | UG Reqs: GER: DB-NatSci
Instructors: ; Chidsey, C. (PI)

CHEM 173: Physical Chemistry

Introduction to quantum chemistry: the basic principles of wave mechanics, the harmonic oscillator, the rigid rotator, infrared and microwave spectroscopy, the hydrogen atom, atomic structure, molecular structure, valence theory. Prerequisites: MATH 51, 53; PHYSICS 41, 43. Recommended: PHYSICS 45.
Terms: Aut | Units: 3 | UG Reqs: GER: DB-NatSci
Instructors: ; Martinez, T. (PI)

CHEM 174: Physical Chemistry Laboratory I

Experimental investigations in spectroscopy, thermodynamics, and electronics. Students take measurements on molecular systems, design and build scientific instruments, and computer-automate them with software that they write themselves. Prerequisites: 134, 171, MATH 51, PHYSICS 44.
Terms: Aut | Units: 4 | UG Reqs: GER: DB-NatSci
Instructors: ; Chidsey, C. (PI)

CHEM 175: Physical Chemistry

Introduction to kinetic theory and statistical mechanics: molecular theory of matter and heat, transport phenomena in gases, Boltzmann distribution law, partition functions for ideal gases. Introduction to chemical kinetics: measurement of rates of reactions, relationship between rate and reaction mechanism, consideration of specific reactions, transition-state theory of reaction rates. Prerequisites: 171, 173.
Terms: Win | Units: 3 | UG Reqs: GER: DB-NatSci
Instructors: ; Markland, T. (PI)

CHEM 176: Physical Chemistry Laboratory

Use of spectroscopic instrumentation to study molecular properties and physical chemical time-dependent processes. Experiments include electronic ultraviolet/visible absorption, fluorescence, Raman, infrared vibrational and nuclear magnetic resonance spectroscopies. Prerequisite: 173.
Terms: Win | Units: 3 | UG Reqs: GER: DB-NatSci
Instructors: ; Fayer, M. (PI)

CHEM 181: Biochemistry I (BIO 188, BIO 288, CHEMENG 181, CHEMENG 281)

(CHEMENG offerings formerly listed as 188/288.) Chemistry of major families of biomolecules including proteins, nucleic acids, carbohydrates, lipids, and cofactors. Structural and mechanistic analysis of properties of proteins including molecular recognition, catalysis, signal transduction, membrane transport, and harvesting of energy from light. Molecular evolution. Satisfies Central Menu Area 1 for Bio majors. Prerequisites: CHEM 33, 35, 131, and 135 or 171.
Terms: Aut | Units: 3 | UG Reqs: GER: DB-NatSci

CHEM 183: Biochemistry II (BIO 189, BIO 289, CHEMENG 183, CHEMENG 283)

Focus on metabolic biochemistry: the study of chemical reactions that provide the cell with the energy and raw materials necessary for life. Topics include glycolysis, gluconeogenesis, the citric acid cycle, oxidative phosphorylation, photosynthesis, the pentose phosphate pathway, and the metabolism of glycogen, fatty acids, amino acids, and nucleotides as well as the macromolecular machines that synthesize RNA, DNA, and proteins. Medical relevance is emphasized throughout. Satisfies Central Menu Area 1 for Bio majors. Prerequisite: BIO 188/288 or CHEM 181 or CHEMENG 181/281 (formerly 188/288).
Terms: Win | Units: 3 | UG Reqs: GER: DB-NatSci
Instructors: ; Dunn, A. (PI)

CHEM 184: Biological Chemistry Laboratory

Modern techniques in biological chemistry including protein purification, characterization of enzyme kinetics, heterologous expression of His-tagged fluorescent proteins, site-directed mutagenesis, and single-molecule fluorescence microscopy. Prerequisite: 181.
Terms: Spr | Units: 4 | UG Reqs: GER: DB-NatSci
Instructors: ; Cegelski, L. (PI)

CHEM 185: Biochemistry III

Advanced biophysical chemistry. Topics include: protein and DNA structure, stability, and folding, membrane lateral organization and dynamics, and transmembrane transport. Prerequisites: 171, 173, 183.
Terms: Spr | Units: 3 | UG Reqs: GER: DB-NatSci
Instructors: ; Boxer, S. (PI); Frank, D. (GP)

CHEMENG 181: Biochemistry I (BIO 188, BIO 288, CHEM 181, CHEMENG 281)

(CHEMENG offerings formerly listed as 188/288.) Chemistry of major families of biomolecules including proteins, nucleic acids, carbohydrates, lipids, and cofactors. Structural and mechanistic analysis of properties of proteins including molecular recognition, catalysis, signal transduction, membrane transport, and harvesting of energy from light. Molecular evolution. Satisfies Central Menu Area 1 for Bio majors. Prerequisites: CHEM 33, 35, 131, and 135 or 171.
Terms: Aut | Units: 3 | UG Reqs: GER: DB-NatSci

CHEMENG 183: Biochemistry II (BIO 189, BIO 289, CHEM 183, CHEMENG 283)

Focus on metabolic biochemistry: the study of chemical reactions that provide the cell with the energy and raw materials necessary for life. Topics include glycolysis, gluconeogenesis, the citric acid cycle, oxidative phosphorylation, photosynthesis, the pentose phosphate pathway, and the metabolism of glycogen, fatty acids, amino acids, and nucleotides as well as the macromolecular machines that synthesize RNA, DNA, and proteins. Medical relevance is emphasized throughout. Satisfies Central Menu Area 1 for Bio majors. Prerequisite: BIO 188/288 or CHEM 181 or CHEMENG 181/281 (formerly 188/288).
Terms: Win | Units: 3 | UG Reqs: GER: DB-NatSci
Instructors: ; Dunn, A. (PI)

COMPMED 81N: Comparative Anatomy and Physiology of Mammals

Preference to freshmen. Emphasis is on a comparative approach to anatomy and physiology of a wide range of mammals, the unique adaptations of each species in terms of its anatomical, and behavioral characteristics, and how these species interact with human beings and other animals. Dissection required. Class size is limited to 16.
Terms: Win | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Bouley, D. (PI)

COMPMED 87Q: Introduction to the Mouse in Biomedical Research

Preference to sophomores. Focus is on the laboratory mouse, a widely used and important research model. Topics include the ethics of animal use in research; the natural history, origin and husbandry of the mouse; characteristics of key mouse strains; its anatomy and physiology; common diseases and their effects on research; coat color genetics relative to human diseases; immunodeficient mouse models; and genetic engineering of mice. The laboratory includes necropsy, handling, anesthesia, identification methods, and common research techniques using live and dead mice. Enrollment limited to 14 students.
Terms: Aut | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Nagamine, C. (PI)

EARTHSYS 4: Evolution and Extinction: Introduction to Historical Geology (GES 4)

Introduction to the basic tools and principles geologists and paleontologists use to reconstruct the history of the Earth. Principles of stratigraphy, correlation, the geological timescale, the history of biodiversity, and the interpretation of fossils. The use of data from sedimentary geology, geochemistry, and paleontology to test theories for critical events in Earth history such as mass extinctions. Two half-day field trips.
Terms: Win | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Payne, J. (PI)

EARTHSYS 8: The Oceans: An Introduction to the Marine Environment

For non-majors and majors in earth science or environmental science. The major ocean ecosystems and how they function both naturally and under the influence of human activities. Emphasis is on the dominant organisms of each ecosystem and how they interact with each other and their physical and chemical environment. The types of ecosystems discussed include coral reefs, deep-sea hydrothermal vents, coastal upwelling systems, blue-water oceans, estuaries, and near-shore dead zones. Lectures, multimedia presentations, and group activities.
Last offered: Spring 2013 | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA

EARTHSYS 10: Introduction to Earth Systems

For non-majors and prospective Earth Systems majors. Multidisciplinary approach using the principles of geology, biology, engineering, and economics to describe how the Earth operates as an interconnected, integrated system. Goal is to understand global change on all time scales. Focus is on sciences, technological principles, and sociopolitical approaches applied to solid earth, oceans, water, energy, and food and population. Case studies: environmental degradation, loss of biodiversity, and resource sustainability.
Terms: Aut | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Ernst, W. (PI)

EARTHSYS 30: Ecology for Everyone (BIO 30)

Everything is connected, but how? Ecology is the science of interactions and the changes they generate. This project-based course links individual behavior, population growth, species interactions, and ecosystem function. Introduction to measurement, observation, experimental design and hypothesis testing in field projects, mostly done in groups. The goal is to learn to think analytically about everyday ecological processes involving bacteria, fungi, plants, animals and humans. The course uses basic statistics to analyze data; there are no math prerequisites except arithmetic. Open to everyone, including those who may be headed for more advanced courses in ecology and environmental science.
Terms: Spr | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Gordon, D. (PI)

EARTHSYS 38N: The Worst Journey in the World: The Science, Literature, and History of Polar Exploration (EESS 38N, GES 38N)

This course examines the motivations and experiences of polar explorers under the harshest conditions on Earth, as well as the chronicles of their explorations and hardships, dating to the 1500s for the Arctic and the 1700s for the Antarctic. Materials include The Worst Journey in the World by Aspley Cherry-Garrard who in 1911 participated in a midwinter Antarctic sledging trip to recover emperor penguin eggs. Optional field trip into the high Sierra in March.
Terms: Win | Units: 3 | UG Reqs: GER: DB-NatSci
Instructors: ; Dunbar, R. (PI)

EARTHSYS 104: The Water Course (GEOPHYS 104)

The pathway that water takes from rainfall to the tap using student home towns as an example. How the geological environment controls the quantity and quality of water; taste tests of water from around the world. Current U.S. and world water supply issues. Offered Spring 2014.
Terms: Spr | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-AQR, WAY-SMA
Instructors: ; Knight, R. (PI)

EARTHSYS 111: Biology and Global Change (BIO 117, EESS 111)

The biological causes and consequences of anthropogenic and natural changes in the atmosphere, oceans, and terrestrial and freshwater ecosystems. Topics: glacial cycles and marine circulation, greenhouse gases and climate change, tropical deforestation and species extinctions, and human population growth and resource use. Prerequisite: Biology or Human Biology core or graduate standing.
Terms: Win | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-SMA

EARTHSYS 116: Ecology of the Hawaiian Islands (BIO 116)

Terrestrial and marine ecology and conservation biology of the Hawaiian Archipelago. Taught in the field in Hawaii as part of quarter-long sequence of courses including Earth Sciences and Anthropology. Topics include ecological succession, plant-soil interactions, conservation biology, biological invasions and ecosystem consequences, and coral reef ecology. Restricted to students accepted into the Earth Systems of Hawaii Program.
Last offered: Autumn 2012 | Units: 4 | UG Reqs: GER: DB-NatSci

EARTHSYS 122: Paleobiology (GES 123)

Introduction to the fossil record with emphasis on marine invertebrates. Major debates in paleontological research. The history of animal life in the oceans. Topics include the nature of the fossil record, evolutionary radiations, mass extinctions, and the relationship between biological evolution and environmental change. Fossil taxa through time. Exercises in phylogenetics, paleoecology, biostratigraphy, and statistical methods.
Last offered: Spring 2013 | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-SMA

EARTHSYS 141: Remote Sensing of the Oceans (EARTHSYS 241, EESS 141, EESS 241, GEOPHYS 141)

How to observe and interpret physical and biological changes in the oceans using satellite technologies. Topics: principles of satellite remote sensing, classes of satellite remote sensors, converting radiometric data into biological and physical quantities, sensor calibration and validation, interpreting large-scale oceanographic features.
Terms: Win | Units: 3-4 | UG Reqs: GER: DB-NatSci, WAY-AQR
Instructors: ; Arrigo, K. (PI)

EARTHSYS 144: Fundamentals of Geographic Information Science (GIS) (EESS 164)

Survey of geographic information including maps, satellite imagery, and census data, approaches to spatial data, and tools for integrating and examining spatially-explicit data. Emphasis is on fundamental concepts of geographic information science and associated technologies. Topics include geographic data structure, cartography, remotely sensed data, statistical analysis of geographic data, spatial analysis, map design, and geographic information system software. Computer lab assignments.
Terms: Aut | Units: 3-4 | UG Reqs: GER: DB-NatSci
Instructors: ; Carbajales, P. (PI)

EARTHSYS 155: Science of Soils (EESS 155)

Physical, chemical, and biological processes within soil systems. Emphasis is on factors governing nutrient availability, plant growth and production, land-resource management, and pollution within soils. How to classify soils and assess nutrient cycling and contaminant fate. Recommended: introductory chemistry and biology.
Terms: Spr | Units: 3-4 | UG Reqs: GER: DB-NatSci, WAY-SMA

EARTHSYS 156: Soil and Water Chemistry (EARTHSYS 256, EESS 156, EESS 256)

(Graduate students register for 256.) Practical and quantitative treatment of soil processes affecting chemical reactivity, transformation, retention, and bioavailability. Principles of primary areas of soil chemistry: inorganic and organic soil components, complex equilibria in soil solutions, and adsorption phenomena at the solid-water interface. Processes and remediation of acid, saline, and wetland soils. Recommended: soil science and introductory chemistry and microbiology.
Terms: Win | Units: 1-4 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Ying, S. (PI)

EARTHSYS 164: Introduction to Physical Oceanography (CEE 164, CEE 262D, EESS 148)

The dynamic basis of oceanography. Topics: physical environment; conservation equations for salt, heat, and momentum; geostrophic flows; wind-driven flows; the Gulf Stream; equatorial dynamics and ENSO; thermohaline circulation of the deep oceans; and tides. Prerequisite: PHYSICS 41 (formerly 53).
Terms: Win | Units: 4 | UG Reqs: GER: DB-NatSci

EARTHSYS 170: Environmental Geochemistry (GES 170, GES 270)

Solid, aqueous, and gaseous phases comprising the environment, their natural compositional variations, and chemical interactions. Contrast between natural sources of hazardous elements and compounds and types and sources of anthropogenic contaminants and pollutants. Chemical and physical processes of weathering and soil formation. Chemical factors that affect the stability of solids and aqueous species under earth surface conditions. The release, mobility, and fate of contaminants in natural waters and the roles that water and dissolved substances play in the physical behavior of rocks and soils. The impact of contaminants and design of remediation strategies. Case studies. Prerequisite: 90 or consent of instructor.
Terms: Win | Units: 4 | UG Reqs: GER: DB-NatSci
Instructors: ; Brown, G. (PI)

EARTHSYS 37N: Climate Change: Science & Society

Preference to freshmen. How and why do greenhouse gases cause climate to change? How will a changing climate affect humans and natural ecosystems? What can be done to prevent climate change and better adapt to the climate change that does occur? Focus is on developing quantitative understanding of these issues rooted in both the physical and social sciences. Exercises based on simple quantitative observations and calculations; algebra only, no calculus.
| Units: 3 | UG Reqs: GER: DB-NatSci

EARTHSYS 39N: The Carbon Cycle: Reducing Your Impact

Preference to freshmen. Changes in the long- and short-term carbon cycle and global climate through the burning of fossil fuels since the Industrial Revolution. How people can shrink their carbon footprints. Long-term sources and sinks of carbon and how they are controlled by tectonics and short-term sources and sinks and the interaction between the biosphere and ocean. How people can shrink their carbon footprints. Held at the Stanford Community Farm.
| Units: 3 | UG Reqs: GER: DB-NatSci

EARTHSYS 56Q: Changes in the Coastal Ocean: The View From Monterey and San Francisco Bays (EESS 56Q)

Preference to sophomores. Recent changes in the California current, using Monterey Bay as an example. Current literature introduces principles of oceanography. Visits from researchers from MBARI, Hopkins, and UCSC. Optional field trip to MBARI and Monterey Bay.
| Units: 3 | UG Reqs: GER: DB-NatSci

ECON 155: Environmental Economics and Policy

Economic sources of environmental problems and alternative policies for dealing with them (technology standards, emissions taxes, and marketable pollution permits). Evaluation of policies addressing regional air pollution, global climate change, water allocation in the western U.S., and the use of renewable resources. Connections between population growth, economic output, environmental quality, and human welfare. Prerequisite: ECON 50.
Terms: Win | Units: 5 | UG Reqs: GER: DB-NatSci, WAY-SI
Instructors: ; Goulder, L. (PI)

EESS 38N: The Worst Journey in the World: The Science, Literature, and History of Polar Exploration (EARTHSYS 38N, GES 38N)

This course examines the motivations and experiences of polar explorers under the harshest conditions on Earth, as well as the chronicles of their explorations and hardships, dating to the 1500s for the Arctic and the 1700s for the Antarctic. Materials include The Worst Journey in the World by Aspley Cherry-Garrard who in 1911 participated in a midwinter Antarctic sledging trip to recover emperor penguin eggs. Optional field trip into the high Sierra in March.
Terms: Win | Units: 3 | UG Reqs: GER: DB-NatSci
Instructors: ; Dunbar, R. (PI)

EESS 111: Biology and Global Change (BIO 117, EARTHSYS 111)

The biological causes and consequences of anthropogenic and natural changes in the atmosphere, oceans, and terrestrial and freshwater ecosystems. Topics: glacial cycles and marine circulation, greenhouse gases and climate change, tropical deforestation and species extinctions, and human population growth and resource use. Prerequisite: Biology or Human Biology core or graduate standing.
Terms: Win | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-SMA

EESS 141: Remote Sensing of the Oceans (EARTHSYS 141, EARTHSYS 241, EESS 241, GEOPHYS 141)

How to observe and interpret physical and biological changes in the oceans using satellite technologies. Topics: principles of satellite remote sensing, classes of satellite remote sensors, converting radiometric data into biological and physical quantities, sensor calibration and validation, interpreting large-scale oceanographic features.
Terms: Win | Units: 3-4 | UG Reqs: GER: DB-NatSci, WAY-AQR
Instructors: ; Arrigo, K. (PI)

EESS 148: Introduction to Physical Oceanography (CEE 164, CEE 262D, EARTHSYS 164)

The dynamic basis of oceanography. Topics: physical environment; conservation equations for salt, heat, and momentum; geostrophic flows; wind-driven flows; the Gulf Stream; equatorial dynamics and ENSO; thermohaline circulation of the deep oceans; and tides. Prerequisite: PHYSICS 41 (formerly 53).
Terms: Win | Units: 4 | UG Reqs: GER: DB-NatSci

EESS 155: Science of Soils (EARTHSYS 155)

Physical, chemical, and biological processes within soil systems. Emphasis is on factors governing nutrient availability, plant growth and production, land-resource management, and pollution within soils. How to classify soils and assess nutrient cycling and contaminant fate. Recommended: introductory chemistry and biology.
Terms: Spr | Units: 3-4 | UG Reqs: GER: DB-NatSci, WAY-SMA

EESS 156: Soil and Water Chemistry (EARTHSYS 156, EARTHSYS 256, EESS 256)

(Graduate students register for 256.) Practical and quantitative treatment of soil processes affecting chemical reactivity, transformation, retention, and bioavailability. Principles of primary areas of soil chemistry: inorganic and organic soil components, complex equilibria in soil solutions, and adsorption phenomena at the solid-water interface. Processes and remediation of acid, saline, and wetland soils. Recommended: soil science and introductory chemistry and microbiology.
Terms: Win | Units: 1-4 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Ying, S. (PI)

EESS 164: Fundamentals of Geographic Information Science (GIS) (EARTHSYS 144)

Survey of geographic information including maps, satellite imagery, and census data, approaches to spatial data, and tools for integrating and examining spatially-explicit data. Emphasis is on fundamental concepts of geographic information science and associated technologies. Topics include geographic data structure, cartography, remotely sensed data, statistical analysis of geographic data, spatial analysis, map design, and geographic information system software. Computer lab assignments.
Terms: Aut | Units: 3-4 | UG Reqs: GER: DB-NatSci
Instructors: ; Carbajales, P. (PI)

EESS 241: Remote Sensing of the Oceans (EARTHSYS 141, EARTHSYS 241, EESS 141, GEOPHYS 141)

How to observe and interpret physical and biological changes in the oceans using satellite technologies. Topics: principles of satellite remote sensing, classes of satellite remote sensors, converting radiometric data into biological and physical quantities, sensor calibration and validation, interpreting large-scale oceanographic features.
Terms: Win | Units: 3-4 | UG Reqs: GER: DB-NatSci, WAY-AQR
Instructors: ; Arrigo, K. (PI)

EESS 56Q: Changes in the Coastal Ocean: The View From Monterey and San Francisco Bays (EARTHSYS 56Q)

Preference to sophomores. Recent changes in the California current, using Monterey Bay as an example. Current literature introduces principles of oceanography. Visits from researchers from MBARI, Hopkins, and UCSC. Optional field trip to MBARI and Monterey Bay.
| Units: 3 | UG Reqs: GER: DB-NatSci

ENGR 31: Chemical Principles with Application to Nanoscale Science and Technology

Preparation for engineering disciplines emphasizing modern technological applications of solid state chemistry. Topics include: crystallography; chemical kinetics and equilibria; thermodynamics of phase changes and reaction; quantum mechanics of chemical bonding, molecular orbital theory, and electronic band structure of crystals; and the materials science of basic electronic and photonic devices. Prerequisite: high school or college chemistry background in stoichiometry, periodicity, Lewis and VSEPR structures, dissolution/precipitation and acid/base reactions, gas laws, and phase behavior.
Terms: Aut | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; McIntyre, P. (PI)

GEOPHYS 20N: Predicting Volcanic Eruptions

Preference to sophomores. The physics and chemistry of volcanic processes and modern methods of volcano monitoring. Volcanoes as manifestations of the Earth's internal energy and hazards to society. How earth scientists better forecast eruptive activity by monitoring seismic activity, bulging of the ground surface, and the discharge of volcanic gases, and by studying deposits from past eruptions. Focus is on the interface between scientists and policy makers and the challenges of decision making with incomplete information. Field trip to Mt. St. Helens, site of the 1980 eruption. Offered Spring quarter 2013-14.
Terms: Spr | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-AQR, WAY-SMA

GEOPHYS 104: The Water Course (EARTHSYS 104)

The pathway that water takes from rainfall to the tap using student home towns as an example. How the geological environment controls the quantity and quality of water; taste tests of water from around the world. Current U.S. and world water supply issues. Offered Spring 2014.
Terms: Spr | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-AQR, WAY-SMA
Instructors: ; Knight, R. (PI)

GEOPHYS 110: Earth on the Edge: Introduction to Geophysics

Introduction to the foundations of contemporary geophysics. Topics drawn from four broad themes in: whole Earth geodynamics, geohazards, natural resources, and environment/sustainability. In each case the focus is on how the interpretation of a variety of geophysical measurements (e.g., gravity, seismology, heat flow, magnetism, electromagnetics, and geodesy) can be used to provide fundamental insight into the behavior of the Earth's complex geosystems. Prerequisite: CME 100 or MA TH 51, or co-registration in either. Offered every year, autumn quarter. Next offering, Autumn 2013-14
Terms: Aut | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-AQR, WAY-SMA
Instructors: ; Beroza, G. (PI)

GEOPHYS 120: Ice, Water, Fire (GEOPHYS 220)

Introductory application of continuum mechanics to ice sheets and glaciers, water waves and tsunamis, and volcanoes. Emphasis on physical processes and mathematical description using balance of mass and momentum, combined with constitutive equations for fluids and solids. Designed for undergraduates with no prior geophysics background; also appropriate for beginning graduate students.nnPrerequisites: CME 100 or MATH 52 and PHYSICS 41 (or equivalent).nnOffered every year, winter quarter (except 2013-2014, when offered in spring).
Terms: Spr | Units: 3-5 | UG Reqs: GER: DB-NatSci, WAY-FR, WAY-SMA
Instructors: ; Dunham, E. (PI)

GEOPHYS 130: Introductory Seismology

Introduction to seismology including: elasticity and the wave equation, P, S, and surface waves, dispersion, ray theory, reflection and transmission of seismic waves, seismic imaging, large-scale Earth structure, earthquake location, earthquake statistics and forecasting, magnitude scales, seismic source theory. Offered every year, Autumn quarter. (Beroza, G)
Terms: Aut | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-AQR, WAY-SMA
Instructors: ; Beroza, G. (PI)

GEOPHYS 141: Remote Sensing of the Oceans (EARTHSYS 141, EARTHSYS 241, EESS 141, EESS 241)

How to observe and interpret physical and biological changes in the oceans using satellite technologies. Topics: principles of satellite remote sensing, classes of satellite remote sensors, converting radiometric data into biological and physical quantities, sensor calibration and validation, interpreting large-scale oceanographic features.
Terms: Win | Units: 3-4 | UG Reqs: GER: DB-NatSci, WAY-AQR
Instructors: ; Arrigo, K. (PI)

GEOPHYS 150: Geodynamics: Our Dynamic Earth

In this course we cover the dynamic forces acting upon the Earth. We will investigate how geophysical forces effect the bending of tectonic plates, the flow of heat, sea level topography, the breaking point of rocks, porous flow, and how faults store and release energy. Math 52 or CME 102, GP 107 or permission from instructor. Offered every year, spring quarter (except 2013-14 when offered in Winter).
Terms: Win | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Lawrence, J. (PI)

GEOPHYS 182: Reflection Seismology (GEOPHYS 222)

The principles of seismic reflection profiling, focusing on methods of seismic data acquisition and seismic data processing for hydrocarbon exploration.
Terms: Aut | Units: 3 | UG Reqs: GER: DB-NatSci
Instructors: ; Klemperer, S. (PI)

GEOPHYS 50N: Planetary Habitability, World View, and Sustainability

Sustainability lessons from the geological past Life on Earth has partially perished in sudden mass extinctions several time over the Earth's history. Threats include actions of our own volition, including fossil fuel burning as well as natural events, including the impact of large asteroids. The end Permian 250 million years ago and end Paleocene 55 million years ago extinctions involved natural burning of fossil fuels. The 65 million year ago end Cretaceous extinction involved the impact of and asteroid and possibly fossil fuel burning. Related sustainability topics in the popular press will be discussed as they arise. Student pairs lead discussions on topics on how humanity might avert these catastrophes. Offered occasionally.
| Units: 3 | UG Reqs: GER: DB-NatSci

GES 1A: Introduction to Geology: The Physical Science of the Earth

For non-majors or prospective majors in the Earth Sciences. Lectures, hands-on laboratories, and three one-day weekend field trips. Focus is on the physical and chemical processes of heat and mass transfer within the earth and its fluid envelopes, including deep-earth, crustal, surface, and atmospheric processes. Topics include the dynamics of and interactions between the inner earth, plate tectonics, surface processes, and atmospheric processes such as climate change and global warming. Only one of GES 1A, 1B, or 1C may be taken for credit. Prerequisites: MATH 19 or equivalent.
Terms: Spr | Units: 5 | UG Reqs: GER: DB-NatSci, WAY-AQR, WAY-SMA
Instructors: ; Hilley, G. (PI)

GES 1B: Introduction to Geology: California Desert Geology

For non-majors and prospective majors or minors in the Earth Sciences. The landscapes and rock formations of California's Death Valley and Owens Valley are used as natural laboratories for studying active geologic processes that shape Earth's surface (earthquakes, mountain building, volcanoes, glaciers) and for tracing a billion years of Earth history, climate change, and historic human impacts. Lectures on these topics and hands-on laboratory exercises involving rock identification and interpreting topographic and geologic maps and satellite imagery provide an introduction to physical geology and the background necessary to appreciate an optional 6-day field trip to these desert areas during the Thanksgiving recess, which can be taken separately as GES183. Only one of GES 1A, 1B, or 1C may be taken for credit. Recommended: high school chemistry.
Terms: Aut | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-FR, WAY-SMA
Instructors: ; Mahood, G. (PI)

GES 1C: Introduction to Geology: Dynamic Earth

For non-majors or prospective majors in the Earth Sciences. Integrated lecture-lab includes hands-on activities and local field trips. Focus is on reading the dynamic geological landscape, with an emphasis on California-primarily Bay Area-geology. Topics include plate tectonics, earthquakes and volcanoes, Earth materials, geologic time, stream processes, and climate change over geologic time. Only one of GES 1A, 1B, or 1C may be taken for credit.
Last offered: Spring 2013 | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-SMA

GES 4: Evolution and Extinction: Introduction to Historical Geology (EARTHSYS 4)

Introduction to the basic tools and principles geologists and paleontologists use to reconstruct the history of the Earth. Principles of stratigraphy, correlation, the geological timescale, the history of biodiversity, and the interpretation of fossils. The use of data from sedimentary geology, geochemistry, and paleontology to test theories for critical events in Earth history such as mass extinctions. Two half-day field trips.
Terms: Win | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Payne, J. (PI)

GES 8: Oceanography: An Introduction to the Marine Environment

For non-majors and earth science and environmental majors. Topics: topography and geology of the sea floor; evolution of ocean basins; circulation of ocean and atmosphere; nature of sea water, waves, and tides; and the history of the major ocean basins. The interface between continents and ocean basins, emphasizing estuaries, beaches, and continental shelves with California margin examples. Relationships among the distribution of inorganic constituents, ocean circulation, biologic productivity, and marine environments from deep sea to the coast. One-day field trip to measure and analyze waves and currents.
Terms: Sum | Units: 3 | UG Reqs: GER: DB-NatSci
Instructors: ; Ingle, J. (PI)

GES 38N: The Worst Journey in the World: The Science, Literature, and History of Polar Exploration (EARTHSYS 38N, EESS 38N)

This course examines the motivations and experiences of polar explorers under the harshest conditions on Earth, as well as the chronicles of their explorations and hardships, dating to the 1500s for the Arctic and the 1700s for the Antarctic. Materials include The Worst Journey in the World by Aspley Cherry-Garrard who in 1911 participated in a midwinter Antarctic sledging trip to recover emperor penguin eggs. Optional field trip into the high Sierra in March.
Terms: Win | Units: 3 | UG Reqs: GER: DB-NatSci
Instructors: ; Dunbar, R. (PI)

GES 39N: Forensic Geoscience: Stanford CSI

Preference to freshmen. Geological principles, materials, and techniques indispensable to modern criminal investigations. Basic earth materials, their origin and variability, and how they can be used as evidence in criminal cases and investigations such as artifact provenance and environmental pollution. Sources include case-based, simulated forensic exercises and the local environments of the Stanford campus and greater Bay Area. Local field trips; research presentation and paper.
Terms: Spr | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-AQR, WAY-SMA
Instructors: ; Maher, K. (PI)

GES 40N: Diamonds

Preference to freshmen. Topics include the history of diamonds as gemstones, prospecting and mining, and their often tragic politics. How diamond samples provide clues for geologists to understand the Earth's deep interior and the origins of the solar system. Diamond's unique materials properties and efforts in synthesizing diamonds.
Last offered: Spring 2011 | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA

GES 43Q: Environmental Problems

Preference to sophomores. Components of multidisciplinary environmental problems and ethical questions associated with decision making in the regulatory arena. Students lead discussions on environmental issues such as groundwater contamination from point and nonpoint sources, cumulative watershed effects related to timber and mining practices, acid rain, and subsurface disposal of nuclear waste.
Terms: Spr | Units: 3 | UG Reqs: GER: DB-NatSci
Instructors: ; Loague, K. (PI)

GES 50Q: The Coastal Zone Environment

Preference to sophomores. The oceanographic, geological, and biological character of coastal zone environments, including continental shelves, estuaries, and coastal wetlands, with emphasis on San Francisco Bay. Five required field trips examine estuarine and coastal environments, and agencies and facilities that manage these resources. Students present original research. Prerequisite: beginning course in Biology such as BIOSCI 51, Chemistry such as CHEM 30 or 31, Earth Sciences such as GES 1 or 2, or Earth Systems such as EARTHSYS 10.
| Units: 3 | UG Reqs: GER: DB-NatSci

GES 55Q: The California Gold Rush: Geologic Background and Environmental Impact

Preference to sophomores. Topics include: geologic processes that led to the concentration of gold in the river gravels and rocks of the Mother Lode region of California; and environmental impact of the Gold Rush due to population increase, mining operations, and high concentrations of arsenic and mercury in sediments from hard rock mining and milling operations. Recommended: introductory geology.
Terms: Win | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA, Writing 2
Instructors: ; Bird, D. (PI)

GES 90: Introduction to Geochemistry

The chemistry of the solid earth and its atmosphere and oceans, emphasizing the processes that control the distribution of the elements in the earth over geological time and at present, and on the conceptual and analytical tools needed to explore these questions. The basics of geochemical thermodynamics and isotope geochemistry. The formation of the elements, crust, atmosphere and oceans, global geochemical cycles, and the interaction of geochemistry, biological evolution, and climate. Recommended: introductory chemistry.
Terms: Win | Units: 3-4 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Stebbins, J. (PI)

GES 102: Earth Materials: Introduction to Mineralogy

The minerals and materials that comprise the earth and their uses in modern society. How to identify, classify, and interpret rock-forming minerals. Emphasis is on information provided by common minerals about the nature of the Earth's interior and processes such as magmatism and metamorphism that operate there, as well as the major processes of weathering and erosion that link plate tectonics to earth cycles. Required lab section. Prerequisite: introductory geology course. Recommended: introductory chemistry.
Terms: Aut | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Brown, G. (PI); Mao, W. (PI)

GES 110: Structural Geology and Tectonics

Theory, principles, and practical techniques to measure, describe, analyze, and interpret deformation-related structures on Earth. Collection of fault and fold data in the field followed by lab and computer analysis; interpretation of geologic maps and methods of cross-section construction; structural analysis of fault zone and metamorphic rocks; measuring deformation; regional structural styles and associated landforms related to plate tectonic convergence, rifting, and strike-slip faulting; the evolution of mountain belts and formation of sedimentary basins. Prerequisite: GES 1, calculus. Recommended: 102.
Terms: Spr | Units: 3-5 | UG Reqs: GER: DB-NatSci
Instructors: ; Miller, E. (PI)

GES 115: Engineering Geology and Global Change (CEE 196)

The application of geology and global change to the planning, design, and operation of engineering projects. Case histories taught in a seminar setting and field trips emphasize the impact of geology and global change on both individual engineering works and the built environment by considering Quaternary history and tectonics, anthropogenic sea level rise, active geologic processes, engineering properties of geologic deposits, site exploration, and professional ethics. Prerequisite: GES 1 or consent of instructor.
| Units: 3 | UG Reqs: GER: DB-NatSci
Instructors: ; Holzer, T. (PI)

GES 123: Paleobiology (EARTHSYS 122)

Introduction to the fossil record with emphasis on marine invertebrates. Major debates in paleontological research. The history of animal life in the oceans. Topics include the nature of the fossil record, evolutionary radiations, mass extinctions, and the relationship between biological evolution and environmental change. Fossil taxa through time. Exercises in phylogenetics, paleoecology, biostratigraphy, and statistical methods.
Last offered: Spring 2013 | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-SMA

GES 130: Soil Physics and Hydrology

The occurrence, distribution, circulation, and reaction of water at the surface and within the near surface. Topics: precipitation, evapotranspiration, infiltration and vadose zone, groundwater, surface water and streamflow generation, and water balance estimates. Current and classic theory in soil physics and hydrology. Urban, rangeland, and forested environments.
Last offered: Autumn 2012 | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA

GES 131: Hydrologically-Driven Landscape Evolution

Materials of the Earth and hydrologically driven landscape processes. Topics: hillslope hydrology, weathering of rocks and soils, erosion, flow failures, mass wasting, and conceptual models of landscape evolution. Current and classic theory in geomorphology.
Last offered: Winter 2013 | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA

GES 151: Sedimentary Geology and Petrography: Depositional Systems

Topics: weathering, erosion and transportation, deposition, origins of sedimentary structures and textures, sediment composition, diagenesis, sedimentary facies, tectonics and sedimentation, and the characteristics of the major siliciclastic and carbonate depositional environments. Lab: methods of analysis of sediments in hand specimen and thin section. Field trips. Prerequisites: 1, 102, 103.
Last offered: Spring 2013 | Units: 4 | UG Reqs: GER: DB-NatSci

GES 170: Environmental Geochemistry (EARTHSYS 170, GES 270)

Solid, aqueous, and gaseous phases comprising the environment, their natural compositional variations, and chemical interactions. Contrast between natural sources of hazardous elements and compounds and types and sources of anthropogenic contaminants and pollutants. Chemical and physical processes of weathering and soil formation. Chemical factors that affect the stability of solids and aqueous species under earth surface conditions. The release, mobility, and fate of contaminants in natural waters and the roles that water and dissolved substances play in the physical behavior of rocks and soils. The impact of contaminants and design of remediation strategies. Case studies. Prerequisite: 90 or consent of instructor.
Terms: Win | Units: 4 | UG Reqs: GER: DB-NatSci
Instructors: ; Brown, G. (PI)

GES 185: Volcanology

For juniors, seniors, and beginning graduate students in earth sciences. Eruptive processes that create volcanic deposits and landforms; relation to physical properties of magmas. Volcanic hazards and the effects of eruptions on climate; volcanic-hosted geothermal systems and mineral resources. Required 4-day field trip over Memorial Day weekend to study silicic and mafic volcanism in the eastern Sierra Nevada. Those taking the class for 4 units will complete a 3-hour weekly lab involving hand specimen and thin section identification and interpretation, which emphasizes recognizing types of lavas and products of explosive eruptions. Prerequisite: 1, for those taking the course for 3 units; 103 and 104 or equivalent for those taking the course for 4 units.
Terms: Spr | Units: 3-4 | UG Reqs: GER: DB-NatSci
Instructors: ; Mahood, G. (PI)

GES 171: Geochemical Thermodynamics

Introduction to the application of chemical principles and concepts to geologic systems. The chemical behavior of fluids, minerals, and gases using simple equilibrium approaches to modeling the geochemical consequences of diagenetic, hydrothermal, metamorphic, and igneous processes. Topics: reversible thermodynamics, solution chemistry, mineral-solution equilibria, reaction kinetics, and the distribution and transport of elements by geologic processes. Prerequisite: GES 102.
| Units: 3 | UG Reqs: GER: DB-NatSci

GES 181: Metamorphic Processes

For juniors, seniors, and beginning graduate students in Earth Sciences. Thermodynamics and phase equilibria of multiple component systems; use of phase equilibria to determine pressure and temperature of metamorphic assemblages; geochronology of metamorphic rocks; heat flow in the lithosphere; links between tectonics and metamorphism; and the role of heat and mass transfer in the Earth's crust and mantle. Labs emphasize identification of metamorphic rocks and minerals for common pelitic and basic rocks and interpretation of rock textures. May be taken for 3 units without lab. Prerequisites: 102, 103, or consent of instructor.
| Units: 3-5 | UG Reqs: GER: DB-NatSci

HUMBIO 2A: Genetics, Evolution, and Ecology

Introduction to the principles of classical and modern genetics, evolutionary theory, and population biology. Topics: micro- and macro-evolution, population and molecular genetics, biodiversity, and ecology, emphasizing the genetics and ecology of the evolutionary process and applications to human populations. HUMBIO 2A and 2B must be taken concurrently.
Terms: Aut | Units: 5 | UG Reqs: GER: DB-NatSci, WAY-SMA

HUMBIO 3A: Cell and Developmental Biology

The principles of the biology of cells: principles of human developmental biology, biochemistry of energetics and metabolism, the nature of membranes and organelles, hormone action and signal transduction in normal and diseased states (diabetes, cancer, autoimmune diseases), drug discovery, immunology, and drug addiction. HUMBIO 3A and 3B must be taken concurrently. Prerequisite: college chemistry or completion of the HumBio chemistry lecture series during the fall quarter.
Terms: Win | Units: 5 | UG Reqs: GER: DB-NatSci, WAY-SMA

HUMBIO 4A: The Human Organism

Organ system physiology: the principles of neurobiology and endocrinology, and the functions of body organs. The mechanisms of control, regulation, and integration of organ systems function. HUMBIO 4A and 4B must be taken concurrently.
Terms: Spr | Units: 5 | UG Reqs: GER: DB-NatSci, WAY-SMA

HUMBIO 6: Human Origins (ANTHRO 6, ANTHRO 206, BIO 106)

The human fossil record from the first non-human primates in the late Cretaceous or early Paleocene, 80-65 million years ago, to the anatomically modern people in the late Pleistocene, between 100,000 to 50,000 B.C.E. Emphasis is on broad evolutionary trends and the natural selective forces behind them.
| Units: 5 | UG Reqs: GER: DB-NatSci

HUMBIO 91Q: Neuroethology: The Neural Control of Behavior

Preference to sophomores. Animal behavior offers insights about evolutionary adaptations and this seminar will discuss the origins of the study of animal behavior and its development to the present. How does the nervous system control behavior and how is it changed by behavior? We will analyze and discuss original research papers about the neural basis of behavior. The use and misuse of parallels between animal and human behavior. Possible field trip to observe animals in their natural habitat.
Terms: Win | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Fernald, R. (PI)

HUMBIO 112: Conservation Biology: A Latin American Perspective (BIO 144, BIO 234)

Principles and application of the science of preserving biological diversity. Conceptually, this course is designed to explore 4 major components relevant to the conservation of biodiversity, as exemplified by the Latin American region. The conceptual frameworks and principles, however, should be generally applicable, and provide insights for all regions of the world, including those of lesser biodiversity. Satisfies Central Menu Area 4 for Bio majors. Prerequisite: BIO 101, or BIO 43 or HUMBIO 2A with consent of instructor. Graduate level students will be expected to conduct a literature research exercise leading to a written paper, addressing a topic of their choosing, derived from any of the themes discussed in class.
Terms: Spr | Units: 3 | UG Reqs: GER: DB-NatSci
Instructors: ; Dirzo, R. (PI)

HUMBIO 133: Human Physiology (BIO 112, BIO 212)

Human physiology will be examined by organ systems: respiratory, cardiovascular, renal, and gastrointestinal. Concepts of cell and molecular biology that underlie organ development, pathophysiology and opportunities for regenerative medicine will be introduced. Signaling and integrative control by the endocrine, autonomic and central nervous systems will be introduced. Prerequisite: Biology or Human Biology core.
Terms: Win | Units: 4 | UG Reqs: GER: DB-NatSci
Instructors: ; Kao, P. (PI)

HUMBIO 145L: The Biology and Evolution of Language (ANTHRO 171, ANTHRO 271)

Lecture course surveying the biology, linguistic functions, and evolution of the organs of speech and speech centers in the brain, language in animals and humans, the evolution of language itself, and the roles of innateness vs. culture in language. Suitable both for general education and as preparation for further studies in anthropology, biology, linguistics, medicine, psychology, and speech & language therapy. Anthropology concentration: CS, EE. No prerequisites.
Terms: Win | Units: 4-5 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Fox, J. (PI)

HUMBIO 156: Global HIV/AIDS (MED 256)

Public health, policy, and research issues. Identify resources at Stanford, and from government, NGOs, and pharmaceutical, advocacy, and international organizations. Sources include biomedical, social, and behavioral sciences. Emphasis on student projects which feature methodologies in the development and design of Operational Research and Implementation Science in AIDS/TB and Malaria in response to PEPFAR and Global Fund programs. Guest lectures. Prerequisite: Human Biology core or equivalent, or consent of instructor.
Terms: Spr | Units: 3 | UG Reqs: GER: DB-NatSci, GER:EC-GlobalCom
Instructors: ; Katzenstein, D. (PI)

HUMBIO 158: The Human Genome and Disease (BIO 109A, BIO 209A, BIOC 109A, BIOC 209A)

The variability of the human genome and the role of genomic information in research, drug discovery, and human health. Concepts and interpretations of genomic markers in medical research and real life applications. Human genomes in diverse populations. Original contributions from thought leaders in academia and industry and interaction between students and guest lecturers. Students with a major, minor or coterm in Biology: 109A/209A or 109B/209B may count toward degree program but not both.
Terms: Win | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA

HUMBIO 158G: Genomics, Bioinformatics and Medicine (BIOC 158, BIOC 258, BIOMEDIN 258)

Molecular basis of inherited human disease. Diagnostics approaches: simple Mendelian diseases and complex, multifactorial diseases. Genomics: functional genomics, epigenetics, gene expression, SNPs, copy number and other structural genomic variations involved in disease. Novel therapeutic methods: stem cell therapy, gene therapy and drug developments that depend on the knowledge of genomics. Personal genomics, pharmacogenomics, clinical genomics and their role in the future of preventive medicine. Prerequisites: BIO 41 or HUMBIO 2A or consent of instructor. Those with credit in BIOC 118 not eligible to enroll. Course webpage: http://biochem158.stanford.edu/
Terms: Aut, Win, Spr | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA | Repeatable 2 times (up to 6 units total)
Instructors: ; Brutlag, D. (PI)

HUMBIO 160: Human Behavioral Biology (BIO 150, BIO 250)

Multidisciplinary. How to approach complex normal and abnormal behaviors through biology. How to integrate disciplines including sociobiology, ethology, neuroscience, and endocrinology to examine behaviors such as aggression, sexual behavior, language use, and mental illness.
Terms: Spr | Units: 5 | UG Reqs: GER: DB-NatSci, WAY-SMA

HUMBIO 161: The Neurobiology of Sleep (BIO 149, BIO 249)

Preference to seniors and graduate students. The neurochemistry and neurophysiology of changes in brain activity and conscious awareness associated with changes in the sleep/wake state. Behavioral and neurobiological phenomena including sleep regulation, sleep homeostasis, circadian rhythms, sleep disorders, sleep function, and the molecular biology of sleep. Enrollment limited to 16.
Last offered: Winter 2013 | Units: 4 | UG Reqs: GER: DB-NatSci

HUMBIO 167: The Art of Vision

This course concerns eyes and art. It asks how eyes are built, how they process visual information, and how they are affected by diseases that are major problems in our society. These topics are illustrated through fine art and famous artists, and we explore the implications of both normal and abnormal vision for art. There are short diversions into animal eyes and the role of vision in music, literature, and sports.
Terms: Win | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-A-II
Instructors: ; Marmor, M. (PI)

HUMBIO 180: Human Skeletal Anatomy (ANTHRO 175, ANTHRO 275, BIO 174, BIO 274)

Study of the human skeleton (a. k. a. human osteology), as it bears on other disciplines, including medicine, forensics, archaeology, and paleoanthropology (human evolution). Basic bone biology, anatomy, and development, emphasizing hands-on examination and identification of human skeletal parts, their implications for determining an individual¿s age, sex, geographic origin, and health status, and for the evolutionary history of our species. Three hours of lecture and at least three hours of supervised and independent study in the lab each week.
Terms: Win | Units: 5 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Klein, R. (PI)

HUMBIO 186: Biological Clocks

The biological basis for endogenous timekeeping in organisms from flies to human beings. How biological clocks are constructed at the molecular, tissue, and behavioral levels; how these clocks interact with other physiological systems and allow animals to anticipate changes in their environment. Applications of circadian rhythm principles to treating human disorders and diseases such as cancer. Prerequisite: Biology or Human Biology core, or consent of instructor.
| Units: 3 | UG Reqs: GER: DB-NatSci

HUMBIO 21: Introduction to Brain and Behavior (BIO 20)

Evolutionary principles to understand how the brain regulates behavior physiologically, and is also influenced by behavioral interactions. Topics include neuron structure and function, transmission of neural information, anatomy and physiology of sensory and motor systems, regulation of body states, the biological basis of learning and memory, and behavioral abnormalities.
| Units: 3 | UG Reqs: GER: DB-NatSci

HUMBIO 163: Neural Systems and Behavior (BIO 163, BIO 263)

The field of neuroethology and its vertebrate and invertebrate model systems. Research-oriented. Readings include reviews and original papers. How animal brains compare; how neural circuits are adapted to species-typical behavior; and how the sensory worlds of different species represent the world. Lectures and required discussions. Satisfies Central Menu Area 3 for Bio majors. Prerequisites: BIO 42, HUMBIO 4A.
| Units: 4 | UG Reqs: GER: DB-NatSci

OSPFLOR 86: Stem Cells in Human Development and Regenerative Medicine

Principles and practice of regenerative medicine. Molecular and developmental biology relevant to the understanding of differentiation and development at the molecular, cellular and organismal levels. Production of lines of multipotent and pluripotent stem cells, the conditions necessary to induce their differentiation into specific lineages and cell types, and their clinical applications. State of the art on the development of regenerative therapies for cartilage injury. Aspects of inherited or acquired diseases that could be potentially treated by stem cell therapies. Quality control and quality assurance necessary for the adequate delivery of stem cell based therapies within current legislative frameworks.
Terms: Win | Units: 4-5 | UG Reqs: GER: DB-NatSci

OSPSANTG 85: Marine Ecology of Chile and the South Pacific

Relationships among physical processes in the ocean, biological productivity, and the exploitation of resources by high-thropic-level predators including human beings. Characterization of ecological patterns; identification of processes operating on marine systems. Open ocean ecosystems, intertidal and benthic regions of the world's oceans, and ecological research developed along coastal regions, focusing on Chile's 4,000 km coastline.
Terms: Spr | Units: 5 | UG Reqs: GER: DB-NatSci
Instructors: ; Jaksic, I. (GP)

PHYSICS 15: The Nature of the Universe

The structure, origin, and evolution of the major components of the Universe: planets, stars, and galaxies. Emphasis is on the formation of the Sun and planets, the evolution of stars, and the structure and content of the Milky Way galaxy. Topics: cosmic enigmas (dark matter, black holes, pulsars, x-ray sources), star birth and death, and the origins of and search for life in the solar system and beyond.
Terms: Aut, Sum | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Bard, D. (PI); Romani, R. (PI)

PHYSICS 16: Cosmic Horizons

The origin and evolution of the universe and its contents: stars, galaxies, quasars. The overall structure of the cosmos and the physical laws that govern matter, space, and time. Topics include the evolution of the cosmos from the origin of the elements and the formation of stars and galaxies, exotic astronomical objects (black holes, quasars, supernovae, and gamma ray bursts), dark matter, inflationary cosmology, and the fate of the cosmos.
Terms: Win | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Allen, S. (PI)

PHYSICS 17: Black Holes

Newton's and Einstein's theories of gravitation and their relationship to the predicted properties of black holes. Their formation and detection, and role in galaxies and high-energy jets. Hawking radiation and aspects of quantum gravity.
Terms: Spr | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Romani, R. (PI)

PHYSICS 18N: Frontiers in Theoretical Physics and Cosmology

Preference to freshmen. The course will begin with a description of the current standard models of gravitation, cosmology, and elementary particle physics. We will then focus on frontiers of current understanding including investigations of very early universe cosmology, string theory, and the physics of black holes.
Terms: Win | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Kachru, S. (PI)

PHYSICS 19: How Things Work: An Introduction to Physics

Introduction to the principles of physics through familiar objects and phenomena, including airplanes, cameras, computers, engines, refrigerators, lightning, radio, microwave ovens, and fluorescent lights. Estimates of real quantities from simple calculations. Prerequisite: high school algebra and trigonometry.
Terms: Aut | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Church, S. (PI)

PHYSICS 21: Mechanics and Heat

For biology, social science, and premedical students. Introduction to Newtonian mechanics, fluid mechanics, theory of heat. Prerequisite: high school algebra and trigonometry; calculus not required.
Terms: Aut, Sum | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA

PHYSICS 21S: Mechanics and Heat with Laboratory

For biology, social science, and premedical students. Labs are an integrated part of the summer course. Introduction to Newtonian mechanics, fluid mechanics, theory of heat. nPrerequisite: high school algebra and trigonometry; calculus not required.
Terms: Sum | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Smith, R. (PI)

PHYSICS 23: Electricity and Optics

Electric charges and currents, magnetism, induced currents; wave motion, interference, diffraction, geometrical optics. Prerequisite: PHYSICS 21.
Terms: Win | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Wechsler, R. (PI)

PHYSICS 23S: Electricity and Optics with Lab

For biology, social science, and premedical students. Labs are an integrated part of the summer courses. Electric charges and currents, magnetism, induced currents; wave motion, interference, diffraction, geometrical optics. nnPrerequisite: PHYSICS 21S or 21.
Terms: Sum | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Nouri, C. (PI)

PHYSICS 25: Modern Physics

Introduction to modern physics. Relativity, quantum mechanics, atomic theory, radioactivity, nuclear reactions, nuclear structure, high energy physics, elementary particles, astrophysics, stellar evolution, and the big bang. Prerequisite: PHYSICS 23 or consent of instructor.
Terms: Spr | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Linde, A. (PI)

PHYSICS 41: Mechanics

Vectors, particle kinematics and dynamics, work, energy, momentum, angular momentum; conservation laws; rigid bodies; mechanical oscillations and waves. Discussions based on use of calculus. Prerequisite: High school physics or PHYSICS 19. MATH 19 or MATH 41 or equivalent. Corequisite: MATH 20 or MATH 42 or MATH 51.
Terms: Win | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-SMA

PHYSICS 43: Electricity and Magnetism

Electrostatics, Coulomb's law, electric fields and fluxes, electric potential, properties of conductors, Gauss's law, capacitors and resistors, DC circuits; magnetic forces and fields, Biot-Savart law, Faraday's law, Ampere's law, inductors, transformers, AC circuits, motors and generators, electric power, Galilean transformation of electric and magnetic fields, Maxwell's equations; limited coverage of electromagnetic fields and special relativity. Prerequisite: PHYSICS 41 or equivalent. MATH 20 or MATH 42 or MATH 51 or equivalent. Recommended corequisite: Math 52.
Terms: Spr | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-SMA

PHYSICS 45: Light and Heat

Reflection and refraction, lenses and lens systems; polarization, interference, and diffraction; temperature, properties of matter and thermodynamics, introduction to kinetic theory of matter. Prerequisites: PHYSICS 41 or equivalent. MATH 20 or MATH 42 or MATH 51 or equivalent.
Terms: Aut, Sum | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Gratta, G. (PI)

PHYSICS 50: Astronomy Laboratory and Observational Astronomy

Introduction to observational astronomy emphasizing the use of optical telescopes. Observations of stars, nebulae, and galaxies in laboratory sessions with 16- and 24-inch telescopes at the Stanford Observatory. Meets one evening per week from dusk until well after dark at the Stanford Observatory. No previous physics required. Limited enrollment. Lab.
Terms: Aut, Sum | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-AQR, WAY-SMA
Instructors: ; Kuo, C. (PI); Meyers, J. (PI)

PHYSICS 61: Mechanics and Special Relativity

(First in a three-part series: PHYSICS 61, PHYSICS 63, PHYSICS 65.) Advanced freshman physics. For students with a strong high school mathematics and physics background contemplating a major in Physics or interested in a rigorous treatment of physics. Special theory of relativity and Newtonian mechanics with multi- variable calculus. Postulates of special relativity, simultaneity, time dilation, length contraction, the Lorentz transformation, causality, and relativistic mechanics. Central forces, contact forces, linear restoring forces. Momentum transport, work, energy, collisions. Angular momentum, torque, moment of inertia in three dimensions. Damped and forced harmonic oscillators. Recommended prerequisites: Mastery of mechanics at the level of AP Physics C and AP Calculus B/C or equivalent. Corequisite: MATH 51.
Terms: Aut | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-FR, WAY-SMA
Instructors: ; Hollberg, L. (PI)

PHYSICS 63: Electricity, Magnetism, and Waves

(Second in a three-part series: PHYSICS 61, PHYSICS 63, PHYSICS 65.) Advanced freshman physics. For students with a strong high school mathematics and physics background contemplating a major in Physics or interested in a rigorous treatment of physics. Electricity, magnetism and waves with some description of optics. Electrostatics and Gauss' law. Electric potential, electric field, conductors, image charges. Other theorems of vector calculus. Electric currents, DC circuits. Moving charges, magnetic field, Ampere's law. Solenoids, transformers, induction, AC circuits, resonance. Relativistic point of view for moving charges. Displacement current, Maxwell's equations. Electromagnetic waves, dielectrics. Diffraction, interference, refraction, reflection, polarization. Prerequisite: PHYSICS 61 and MATH 51; Pre- or corequisite: MATH 52.
Terms: Win | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-FR, WAY-SMA
Instructors: ; Graham, P. (PI)

PHYSICS 65: Quantum and Thermal Physics

(Third in a three-part series: PHYSICS 61, PHYSICS 63, PHYSICS 65.) Advanced freshman physics. For students with a strong high school mathematics and physics background contemplating a major in Physics or interested in a rigorous treatment of physics. Introduction to quantum mechanics: matter waves, atomic structure, Schrödinger's equation. Thermodynamics and statistical mechanics: entropy and heat, Boltzmann statistics, quantum statistics. Prerequisites: PHYSICS 61 & PHYSICS 63. Pre- or corequisite: MATH 53.
Terms: Spr | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-FR, WAY-SMA
Instructors: ; Manoharan, H. (PI)

PHYSICS 70: Foundations of Modern Physics

Required for Physics majors who completed the PHYSICS 40 series, or the PHYSICS 60 series prior to 2005-06. Special relativity, the experimental basis of quantum theory, atomic structure, quantization of light, Schrödinger equation, nuclear physics, elementary particles and cosmology. Prerequisites: PHYSICS 41, PHYSICS 43. Pre or corequisite: PHYSICS 45. Recommended: prior or concurrent registration in MATH 53.
Terms: Aut | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Linde, A. (PI)

PHYSICS 83N: Physics in the 21st Century

Preference to freshmen. Current topics at the frontier of modern physics. Topics include subatomic particles and the standard model, symmetries in nature, extra dimensions of space, string theory, supersymmetry, the big bang theory of the origin of the universe, black holes, dark matter, and dark energy of the universe. Why the sun shines. Cosmology and inflation.
Terms: Spr | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Dimopoulos, S. (PI)

PHYSICS 100: Introduction to Observational and Laboratory Astronomy

Designed for undergraduate physics majors but open to all students with a calculus-based physics background and some laboratory experience. Students make and analyze observations using telescopes at the Stanford Student Observatory. Topics include navigating the night sky, the physics of stars and galaxies, telescope instrumentation and operation, quantitative error analysis, and effective scientific communication. Limited enrollment. Prerequisites: prior completion of Physics 40 or PHYSICS 60 series.
Terms: Spr | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-AQR, WAY-SMA

PHYSICS 105: Intermediate Physics Laboratory I: Analog Electronics

Analog electronics including Ohm's law, passive circuits and transistor and op amp circuits, emphasizing practical circuit design skills to prepare undergraduates for laboratory research. Short design project. Minimal use of math and physics, no electronics experience assumed beyond introductory physics. Prerequisite: PHYSICS 43 or PHYSICS 63.
Terms: Aut | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-AQR, WAY-SMA
Instructors: ; Pam, R. (PI)

PHYSICS 110: Advanced Mechanics (PHYSICS 210)

Lagrangian and Hamiltonian mechanics. Principle of least action, Euler-Lagrange equations. Small oscillations and beyond. Symmetries, canonical transformations, Hamilton-Jacobi theory, action-angle variables. Introduction to classical field theory. Selected other topics, including nonlinear dynamical systems, attractors, chaotic motion. Undergraduates register for Physics 110 (4 units). Graduates register for Physics 210 (3 units). (Graduate student enrollees will be required to complete additional assignments in a format determined by the instructor.) Prerequisites: MATH 131P, and PHYS 112 or MATH elective 104 or higher. Recommended prerequisite: PHYS 130.
Terms: Aut | Units: 3-4 | UG Reqs: GER: DB-NatSci, WAY-FR, WAY-SMA
Instructors: ; Qi, X. (PI)

PHYSICS 112: Mathematical Methods of Physics

Theory of complex variables, complex functions, and complex analysis. Fourier series and Fourier transforms. Special functions such as Laguerre, Legendre, and Hermite polynomials, and Bessel functions. The uses of Green's functions. Covers material of MATH 106 and MATH 132 most pertinent to Physics majors. Prerequisites: MATH 50 or 50H series, and MATH 131P or MATH 173.
Terms: Win | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-FR
Instructors: ; Raghu, S. (PI)

PHYSICS 113: Computational Physics

Numerical methods for solving problems in mechanics, electromagnetism, quantum mechanics, and statistical mechanics. Methods include numerical integration; solutions of ordinary and partial differential equations; solutions of the diffusion equation, Laplace's equation and Poisson's equation with relaxation methods; statistical methods including Monte Carlo techniques; matrix methods and eigenvalue problems. Short introduction to MatLab, used for class examples; class projects may be programmed in any language such as C. Prerequisites: MATH 53 and PHYS 120. Previous programming experience not required.
Terms: Aut | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-AQR, WAY-FR
Instructors: ; Abel, T. (PI)

PHYSICS 120: Intermediate Electricity and Magnetism I

(First in a two-part series: PHYS 120, PHYS 121.) Vector analysis. Electrostatic fields, including boundary-value problems and multipole expansion. Dielectrics, static and variable magnetic fields, magnetic materials. Maxwell's equations. Prerequisites: PHYSICS 43 or PHYS 63; MATH 52 and MATH 53. Pre- or corequisite: MATH 131P or MATH 173. Recommended corequisite: PHYS 112.
Terms: Win | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-FR, WAY-SMA
Instructors: ; Church, S. (PI)

PHYSICS 130: Quantum Mechanics

The origins of quantum mechanics and wave mechanics. Schrödinger equation and solutions for one-dimensional systems. Commutation relations. Generalized uncertainty principle. Time-energy uncertainty principle. Separation of variables and solutions for three-dimensional systems; application to hydrogen atom. Spherically symmetric potentials and angular momentum eigenstates. Spin angular momentum. Addition of angular momentum. Prerequisites: PHYSICS 65 or PHYSICS 70. Pre- or corequisites: PHYSICS 120 and MATH 131P or MATH 173.
Terms: Win | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-FR, WAY-SMA
Instructors: ; Hartnoll, S. (PI)

PSYC 135: Sleep and Dreams (PSYC 235)

Current research on how sleep affects our daily lives. Physiology of non-REM and REM sleep, dreams and dreaming, content, psychophysiological cause, lucid dreaming, sleep need, sleep debt, daytime alertness, and performance; biological clock and circadian rhythms; sleep disorders, insomnia, narcolepsy, sleep apnea, sleepwalking, jet lag, sleeping pills, sleep and mental illness, sleep and memory, and the impact of sleep deprivation and sleep disorders on academic and social life. Multimedia presentations, guest lectures, and projects.
Terms: Win, Spr | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA

PSYCH 30: Introduction to Perception

Behavioral and neural aspects of perception focusing on visual and auditory perception. Topics include: scientific methods for studying perception, anatomy and physiology of the visual and auditiory systems, color vision, depth perception, motion perception, stereopsis, visual recognition, pitch and loudness perception, speech perception, and reorganization of the visual system in the blind. nEnrollment open to incoming freshman.
Terms: Aut | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SI, WAY-SMA

PSYCH 50: Introduction to Cognitive Neuroscience

Survey of topics relating brain activity to cognitive processes and behavior. The course begins with an overview of neurophysiology and techniques to measure brain activity. We then discuss perceptual and motor processes before investigating neural responses related to attention, memory, and cognitive control. The course concludes with a discussion of brain processes related to reward, decision making, and social cognition.
Terms: Win | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-SI, WAY-SMA
Instructors: ; McClure, S. (PI)

PSYCH 120: Cellular Neuroscience: Cell Signaling and Behavior (BIO 153)

Neural interactions underlying behavior. Prerequisites: PSYCH 1 or basic biology.
Terms: Aut | Units: 4 | UG Reqs: GER: DB-NatSci, WAY-SMA

PUBLPOL 122: Biosecurity and Bioterrorism Response

Overview of the most pressing biosecurity issues facing the world today. Guest lecturers have included former Secretary of State Condoleezza Rice, former Special Assistant on BioSecurity to Presidents Clinton and Bush Jr. Dr. Ken Bernard, Chief Medical Officer of the Homeland Security Department Dr. Alex Garza, eminent scientists, innovators and physicians in the field, and leaders of relevant technology companies. How well the US and global healthcare systems are prepared to withstand a pandemic or a bioterrorism attack, how the medical/healthcare field, government, and the technology sectors are involved in biosecurity and pandemic or bioterrorism response and how they interface, the rise of synthetic biology with its promises and threats, global bio-surveillance, making the medical diagnosis, isolation, containment, hospital surge capacity, stockpiling and distribution of countermeasures, food and agriculture biosecurity, new promising technologies for detection of bio-threats and countermeasures. Open to medical, graduate, and undergraduate students. No prior background in biology necessary. 4 units for twice weekly attendance (Mon. and Wed.); additional 1 unit for writing a research paper for 5 units total maximum.
Terms: Spr | Units: 4-5 | UG Reqs: GER: DB-NatSci, GER:EC-GlobalCom
Instructors: ; Trounce, M. (PI)

UGXFER NATSCI: GER DB-NATSCI SUBSTITUTION

| Units: 0-99 | UG Reqs: GER: DB-NatSci | Repeatable for credit

UGXFER GER2A1: GER 2A SUBSTITUTION (1ST)

| Units: 0-99 | UG Reqs: GER: DB-NatSci | Repeatable for credit

UGXFER GER2A2: GER 2A SUBSTITUTION (2ND)

| Units: 0 | UG Reqs: GER: DB-NatSci | Repeatable for credit
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